sb 203580 has been researched along with chelerythrine in 18 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (chelerythrine) | Trials (chelerythrine) | Recent Studies (post-2010) (chelerythrine) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 1,115 | 1 | 269 |
| Protein | Taxonomy | sb 203580 (IC50) | chelerythrine (IC50) |
|---|---|---|---|
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | 1.2 | |
| Cholinesterase | Homo sapiens (human) | 8.58 | |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | 0.55 | |
| Acetylcholinesterase | Homo sapiens (human) | 1.45 | |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | 0.566 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 12 (66.67) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M | 1 |
| Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A | 1 |
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Imura, T; Kageyama, T; Kimura, J; Shimohama, S | 1 |
| Chentoufi, J; Honbo, N; Kacimi, R; Karliner, JS; Long, CS | 1 |
| Caivano, M; Cohen, P; Davies, SP; Reddy, H | 1 |
| Blanquet, PR; Derer, P; Mariani, J | 1 |
| Baker, JE; Eis, AL; Fitzpatrick, CM; Jaquiss, RD; Komorowski, RA; Litwin, SB; Mussatto, K; Ogawa, H; Pritchard, KA; Rafiee, P; Shi, Y; Tweddell, JS | 1 |
| Galiñanes, M; Hassouna, A; Loubani, M | 1 |
| Akazawa-Kudoh, S; Kajinami, K; Kanda, T; Kanemitsu, S; Lin, J; Matsui, S; Okubo, S; Takeda, K; Takekoshi, N; Tsugawa, H | 1 |
| Andreka, P; Bishopric, NH; Evans, WH; Haywood, GA; Martin, PE; Turner, MS; Webster, KA; You, L | 1 |
| Dai, JR; Deretey, E; Foster, JE; Ng, W; Pasternak, A; Redden, PR; Reid, N; Slon-Usakiewicz, JJ; Toledo-Sherman, L | 1 |
| Hoffmann, EK; Marshall, WS; Ossum, CG | 1 |
| Galiñanes, M; Kubal, C; Nadal-Ginard, B; Sheth, K | 1 |
| Binion, DG; Floer, M; Manley, S; Nelson, VM; Rafiee, P; Shaker, R; Wellner, M | 1 |
| Choi, S; Jiao, HY; Jun, JY; Kim, MW; Kim, SW; Lee, MJ; Na, J; Park, CG; Park, IK; Shin, DH; So, I | 1 |
| Al Mamun Bhuyan, A; Cao, H; Lang, F | 1 |
| Almeida-Pereira, G; Antunes-Rodrigues, J; Cognuck, SQ; Coletti, R; Elias, LLK; Silva, HVP; Vilhena-Franco, T | 1 |
18 other study(ies) available for sb 203580 and chelerythrine
| Article | Year |
|---|---|
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases | 2007 |
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase | 2013 |
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Selective induction of glial glutamate transporter GLT-1 by hypertonic stress in C6 glioma cells.
Topics: Alkaloids; Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Benzophenanthridines; Biological Transport; Carrier Proteins; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 3; Flavonoids; Gene Expression Regulation, Neoplastic; Glioma; Glutamate Plasma Membrane Transport Proteins; Hypertonic Solutions; Imidazoles; Kinetics; Mitogen-Activated Protein Kinases; Phenanthridines; Phosphorylation; Pyridines; Rats; Reverse Transcriptase Polymerase Chain Reaction; Symporters; Transcription, Genetic; Tumor Cells, Cultured | 1999 |
Hypoxia differentially regulates stress proteins in cultured cardiomyocytes: role of the p38 stress-activated kinase signaling cascade, and relation to cytoprotection.
Topics: Alkaloids; Analysis of Variance; Animals; Benzophenanthridines; Cell Hypoxia; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Imidazoles; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase Kinases; Myocardium; Oxidative Phosphorylation; Phenanthridines; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Rats; Receptors, Estrogen; RNA, Messenger; Signal Transduction; Tyrphostins | 2000 |
Specificity and mechanism of action of some commonly used protein kinase inhibitors.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Amides; Animals; Benzamides; Benzophenanthridines; Benzopyrans; Butadienes; Cell Line; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Indoles; Inhibitory Concentration 50; Isoquinolines; Lithium; Magnesium; Nitriles; Phenanthridines; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Sirolimus; Substrate Specificity; Sulfonamides | 2000 |
A calcium/calmodulin kinase pathway connects brain-derived neurotrophic factor to the cyclic AMP-responsive transcription factor in the rat hippocampus.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Androstadienes; Animals; Antibodies; Benzophenanthridines; Benzopyrans; Blotting, Western; Brain-Derived Neurotrophic Factor; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Carbazoles; Cell Nucleus; Chromones; Cyclic AMP Response Element-Binding Protein; Cytosol; Enzyme Inhibitors; Flavonoids; Hippocampus; Imidazoles; Immunohistochemistry; In Vitro Techniques; Indoles; Intracellular Signaling Peptides and Proteins; Male; Morpholines; Naphthalenes; Phenanthridines; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Rats; Signal Transduction; Time Factors; Tyrphostins; Wortmannin | 2003 |
Cellular redistribution of inducible Hsp70 protein in the human and rabbit heart in response to the stress of chronic hypoxia: role of protein kinases,.
Topics: Alkaloids; Animals; Benzophenanthridines; Blotting, Western; Curcumin; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Female; Heart; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Hypoxia; Imidazoles; Immunohistochemistry; Infant; Infant, Newborn; Ischemia; Male; MAP Kinase Signaling System; Membrane Proteins; Myocardium; Phenanthridines; Protein Kinase C; Pyridines; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors | 2003 |
Delayed preconditioning of the human myocardium: signal transduction and clinical implications.
Topics: Acetylcholine; Aged; Alkaloids; Anisomycin; Antihypertensive Agents; Benzophenanthridines; Culture Techniques; Decanoic Acids; Diazoxide; Enzyme Activation; Enzyme Inhibitors; Female; Heart Atria; Humans; Hydroxy Acids; Imidazoles; Ischemic Preconditioning, Myocardial; Male; Middle Aged; Mitogen-Activated Protein Kinases; Myocardial Ischemia; Myocardium; p38 Mitogen-Activated Protein Kinases; Phenanthridines; Phenylephrine; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Pyridines; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 2004 |
Transient glucose deprivation causes upregulation of heme oxygenase-1 and cyclooxygenase-2 expression in cardiac fibroblasts.
Topics: Alkaloids; Animals; Antioxidants; Benzophenanthridines; Cells, Cultured; Cyclooxygenase 2; Enzyme Activation; Fibroblasts; Glucose; Heat-Shock Proteins; Heme Oxygenase (Decyclizing); Imidazoles; Isoenzymes; Myocardium; Oxygenases; p38 Mitogen-Activated Protein Kinases; Phenanthridines; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Transport; Pyridines; Rats; Reactive Oxygen Species; RNA, Messenger; Up-Regulation | 2004 |
Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels.
Topics: Adenosine Triphosphate; Alkaloids; Aminoimidazole Carboxamide; Animals; Antimycin A; Benzophenanthridines; Brefeldin A; Carbazoles; Cell Hypoxia; Cells, Cultured; Connexin 43; Cycloheximide; Deoxyglucose; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Myocardial Contraction; Myocytes, Cardiac; Okadaic Acid; Ouabain; Phenanthridines; Phosphorylation; Potassium Cyanide; Protein Processing, Post-Translational; Pyridines; Pyrroles; Rats; Recombinant Fusion Proteins; Ribonucleotides; Staurosporine; Tacrolimus; Tetradecanoylphorbol Acetate | 2004 |
Global kinase screening. Applications of frontal affinity chromatography coupled to mass spectrometry in drug discovery.
Topics: Alkaloids; Animals; Benzophenanthridines; Binding Sites; Binding, Competitive; Catalytic Domain; Chromatography, Affinity; Drug Evaluation, Preclinical; Humans; Imidazoles; Mass Spectrometry; Mice; Molecular Structure; Peptides; Phosphorylation; Protein Binding; Protein Kinase C-alpha; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Quinazolines; Receptor, EphB2; Recombinant Proteins | 2005 |
Hypotonic shock mediation by p38 MAPK, JNK, PKC, FAK, OSR1 and SPAK in osmosensing chloride secreting cells of killifish opercular epithelium.
Topics: Alkaloids; Animals; Benzophenanthridines; Blotting, Western; Chlorides; Cyclic AMP-Dependent Protein Kinases; Electrophoresis, Polyacrylamide Gel; Electrophysiology; Epithelium; Focal Adhesion Protein-Tyrosine Kinases; Fundulidae; Imidazoles; Immunohistochemistry; Ion Channels; Isoquinolines; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Models, Biological; Nova Scotia; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phenanthridines; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; Saline Solution, Hypertonic; Sulfonamides; Tamoxifen; Water-Electrolyte Balance | 2005 |
Bone marrow cells have a potent anti-ischemic effect against myocardial cell death in humans.
Topics: Alkaloids; Apoptosis; Benzophenanthridines; Bone Marrow Cells; Cell Death; Heart; Heart Atria; Humans; Imidazoles; In Vitro Techniques; Models, Cardiovascular; Myocardial Ischemia; Myocardium; Necrosis; p38 Mitogen-Activated Protein Kinases; Phosphotransferases; Protein Kinase C; Protein Kinase Inhibitors; Pyridines | 2006 |
Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-kappaB.
Topics: Anthracenes; Anti-Inflammatory Agents; Benzophenanthridines; Cell Line; Curcumin; Enzyme Activation; Epithelial Cells; Esophagus; Flavonoids; Humans; Hydrogen-Ion Concentration; Imidazoles; Interleukin-6; Interleukin-8; Mitogen-Activated Protein Kinases; Mucous Membrane; NF-kappa B; Peptides; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Telomerase; Time Factors; Transcription, Genetic; Up-Regulation | 2009 |
Regulatory Roles of Endogenous Mitogen-Activated Protein Kinases and Tyrosine Kinases in the Pacemaker Activity of Colonic Interstitial Cells of Cajal.
Topics: Animals; Anthracenes; Benzophenanthridines; Cells, Cultured; Chromones; Colon; Flavonoids; Genistein; Imidazoles; Interstitial Cells of Cajal; Intestine, Small; Membrane Potentials; Mice; Mitogen-Activated Protein Kinases; Morpholines; Naphthalenes; Protein-Tyrosine Kinases; Pyridines; Rifabutin | 2015 |
Triggering of Eryptosis, the Suicidal Erythrocyte Death by Mammalian Target of Rapamycin (mTOR) inhibitor Temsirolimus.
Topics: Aniline Compounds; Annexin A5; Antineoplastic Agents; Benzamides; Benzophenanthridines; Calcium; Casein Kinase I; Caspases; Ceramides; Eryptosis; Erythrocytes; Fluoresceins; Gene Expression Regulation; Hemolysis; Humans; Imidazoles; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Phosphatidylserines; Primary Cell Culture; Protein Kinase Inhibitors; Pyridines; Reactive Oxygen Species; Signal Transduction; Sirolimus; Staurosporine; TOR Serine-Threonine Kinases; Xanthenes | 2017 |
17β-Estradiol attenuates p38MAPK activity but not PKCα induced by angiotensin II in the brain.
Topics: Angiotensin II; Animals; Benzophenanthridines; Brain; Drinking; Drug Interactions; Estradiol; Female; Homeostasis; Imidazoles; MAP Kinase Signaling System; Ovariectomy; Oxytocin; p38 Mitogen-Activated Protein Kinases; Protein Kinase C-alpha; Pyridines; Rats, Wistar; Vasopressins | 2019 |