Page last updated: 2024-09-05

sb 203580 and buthionine sulfoximine

sb 203580 has been researched along with buthionine sulfoximine in 8 studies

Compound Research Comparison

Studies
(sb 203580)
Trials
(sb 203580)
Recent Studies (post-2010)
(sb 203580)
Studies
(buthionine sulfoximine)
Trials
(buthionine sulfoximine)
Recent Studies (post-2010) (buthionine sulfoximine)
3,48941,1372,4608408

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (75.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asai, Y; Gon, Y; Hashimoto, S; Horie, T; Machino, T; Matsumoto, K; Takeshita, I1
Ho, YS; Lee, HM; Lin, CH; Thum, WY; Wu, CH1
Cederbaum, A; Wu, D1
Arai, F; Hirao, A; Hosokawa, K; Ikeda, Y; Ito, K; Matsuoka, S; Miyamoto, K; Naka, K; Ohmura, M; Suda, T; Takubo, K1
Ito, Y; Nagasawa, T; Nishizawa, N; Oumi, S1
Fanjul-Moles, ML; Gonsebatt, ME; Hernández, NA; Limón-Pacheco, JH1
Haddad, JJ1
Kayama, T; Kitanaka, C; Narita, Y; Okada, M; Sato, A; Seino, S; Shibui, S; Shibuya, K; Watanabe, E1

Other Studies

8 other study(ies) available for sb 203580 and buthionine sulfoximine

ArticleYear
Regulation by intracellular glutathione of TNF-alpha-induced p38 MAP kinase activation and RANTES production by human pulmonary vascular endothelial cells.
    Allergy, 2000, Volume: 55, Issue:5

    Topics: Acetylcysteine; Buthionine Sulfoximine; Cells, Cultured; Chemokine CCL5; Endothelium, Vascular; Glutathione; Humans; Imidazoles; Immunoblotting; Lung; Mitogen-Activated Protein Kinases; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Pyridines; Time Factors; Tumor Necrosis Factor-alpha

2000
Involvement of p38 mitogen-activated protein kinase in PLL-AGE-induced cyclooxgenase-2 expression.
    European journal of pharmacology, 2002, Mar-08, Volume: 438, Issue:3

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cell Line; Cyclooxygenase 1; Cyclooxygenase 2; Dose-Response Relationship, Drug; Enzyme Activation; Genistein; Glycation End Products, Advanced; Imidazoles; Isoenzymes; Lipopolysaccharides; Mitogen-Activated Protein Kinases; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Polylysine; Polymyxin B; Prostaglandin-Endoperoxide Synthases; Pyridines; Reactive Oxygen Species

2002
Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-kappaB DNA binding activity.
    Molecular pharmacology, 2004, Volume: 66, Issue:3

    Topics: Animals; Buthionine Sulfoximine; Cells, Cultured; Cytochrome P-450 CYP2E1; DNA; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Glutathione; Hepatocytes; Humans; Imidazoles; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Reactive Oxygen Species

2004
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells.
    Nature medicine, 2006, Volume: 12, Issue:4

    Topics: Animals; Buthionine Sulfoximine; Cell Culture Techniques; Cell Line; Cellular Senescence; Coculture Techniques; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Free Radical Scavengers; Hematopoietic Stem Cells; Imidazoles; Immunohistochemistry; Mice; Mice, Congenic; Mice, Inbred C57BL; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Up-Regulation

2006
Oxidative stress induces phosphoenolpyruvate carboxykinase expression in H4IIE cells.
    Bioscience, biotechnology, and biochemistry, 2006, Volume: 70, Issue:9

    Topics: Animals; Blotting, Northern; Buthionine Sulfoximine; Cell Line, Tumor; Ferric Compounds; Flow Cytometry; Gene Expression Regulation, Enzymologic; Glucose; Imidazoles; Liver; Male; MAP Kinase Signaling System; Nitrilotriacetic Acid; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peroxides; Phosphoenolpyruvate Carboxykinase (ATP); Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; RNA, Messenger; Thiobarbituric Acid Reactive Substances

2006
Glutathione depletion activates mitogen-activated protein kinase (MAPK) pathways that display organ-specific responses and brain protection in mice.
    Free radical biology & medicine, 2007, Nov-01, Volume: 43, Issue:9

    Topics: Acetylcysteine; Activating Transcription Factor 2; Animals; Antioxidants; Brain; Butadienes; Buthionine Sulfoximine; Glutathione; Imidazoles; Kidney; Liver; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; NF-kappa B; Nitriles; Oxidative Stress; Proto-Oncogene Proteins c-jun; Pyridines; Reactive Oxygen Species; Sulfhydryl Compounds

2007
A redox microenvironment is essential for MAPK-dependent secretion of pro-inflammatory cytokines: modulation by glutathione (GSH/GSSG) biosynthesis and equilibrium in the alveolar epithelium.
    Cellular immunology, 2011, Volume: 270, Issue:1

    Topics: Acetylcysteine; Alveolar Epithelial Cells; Buthionine Sulfoximine; Cells, Cultured; Enzyme Activation; Glutamate-Cysteine Ligase; Glutathione Disulfide; Humans; Imidazoles; Interleukin-1beta; Interleukin-6; MAP Kinase Signaling System; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pulmonary Alveoli; Pyridines; Tumor Necrosis Factor-alpha

2011
Pivotal role for ROS activation of p38 MAPK in the control of differentiation and tumor-initiating capacity of glioma-initiating cells.
    Stem cell research, 2014, Volume: 12, Issue:1

    Topics: Acetylcysteine; Animals; Brain Neoplasms; Buthionine Sulfoximine; Cell Differentiation; Down-Regulation; Forkhead Box Protein O3; Forkhead Transcription Factors; Glioma; Humans; Hydrogen Peroxide; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 7; Neoplastic Stem Cells; p38 Mitogen-Activated Protein Kinases; Pyridines; Reactive Oxygen Species; RNA Interference; Transplantation, Heterologous

2014