sb 203580 has been researched along with brefeldin a in 8 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (brefeldin a) | Trials (brefeldin a) | Recent Studies (post-2010) (brefeldin a) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 2,600 | 1 | 456 |
| Protein | Taxonomy | sb 203580 (IC50) | brefeldin a (IC50) |
|---|---|---|---|
| major prion protein preproprotein Prp precursor | Homo sapiens (human) | 3.505 | |
| nuclear receptor subfamily 0 group B member 1 | Homo sapiens (human) | 0.1343 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Cruciani, V; Mikalsen, SO | 1 |
| Andreka, P; Bishopric, NH; Evans, WH; Haywood, GA; Martin, PE; Turner, MS; Webster, KA; You, L | 1 |
| Aizu-Yokota, E; Kasahara, T; Murakami, Y; Ohta, S; Sonoda, Y | 1 |
| Choi, KH; Eo, SK; Kim, K; Kim, SM; Lee, KA; Moon, YS; Rhim, BY; Son, YH; Sung, SC | 1 |
| Chae, HJ; Chae, SW; Kim, DS; Kim, HR; Kim, HT; Kim, JH; Lee, GH; Lim, JM | 1 |
| Goto, K; Hozumi, Y; Nakano, T; Wakabayashi, I | 1 |
| Ansorena, E; de Galarreta, MR; Garzón, AG; Iraburu, MJ; López-Zabalza, MJ; Martínez-Irujo, JJ; Mòdol, T; Navarro, A | 1 |
8 other study(ies) available for sb 203580 and brefeldin a
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Mechanisms involved in responses to the poroxisome proliferator WY-14,643 on gap junctional intercellular communication in V79 hamster fibroblasts.
Topics: Acetophenones; Androstadienes; Animals; Benzopyrans; Brefeldin A; Butadienes; Cell Communication; Cells, Cultured; Cricetinae; Cricetulus; Enzyme Inhibitors; Flavonoids; Gap Junctions; Imidazoles; Indoles; Maleimides; Mesocricetus; Mitogen-Activated Protein Kinases; Nitriles; Peroxisome Proliferators; Protein Kinase C; Protein Synthesis Inhibitors; Pyridines; Pyrimidines; Signal Transduction; Sirolimus; Wortmannin | 2002 |
Reversible connexin 43 dephosphorylation during hypoxia and reoxygenation is linked to cellular ATP levels.
Topics: Adenosine Triphosphate; Alkaloids; Aminoimidazole Carboxamide; Animals; Antimycin A; Benzophenanthridines; Brefeldin A; Carbazoles; Cell Hypoxia; Cells, Cultured; Connexin 43; Cycloheximide; Deoxyglucose; Flavonoids; Imidazoles; Indoles; JNK Mitogen-Activated Protein Kinases; Maleimides; Myocardial Contraction; Myocytes, Cardiac; Okadaic Acid; Ouabain; Phenanthridines; Phosphorylation; Potassium Cyanide; Protein Processing, Post-Translational; Pyridines; Pyrroles; Rats; Recombinant Fusion Proteins; Ribonucleotides; Staurosporine; Tacrolimus; Tetradecanoylphorbol Acetate | 2004 |
Suppression of endoplasmic reticulum stress-induced caspase activation and cell death by the overexpression of Bcl-xL or Bcl-2.
Topics: Animals; Anthracenes; Apoptosis; bcl-X Protein; Brefeldin A; Caspase 2; Caspase 9; Cytochromes c; Endoplasmic Reticulum; Enzyme Activation; Imidazoles; JNK Mitogen-Activated Protein Kinases; NFI Transcription Factors; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Pyridines; Rats; Transfection | 2007 |
7-Ketocholesterol upregulates interleukin-6 via mechanisms that are distinct from those of tumor necrosis factor-alpha, in vascular smooth muscle cells.
Topics: Animals; Anthracenes; Brefeldin A; CCAAT-Enhancer-Binding Proteins; Cells, Cultured; Dactinomycin; ELAV Proteins; Humans; Imidazoles; Interleukin-6; Ketocholesterols; Muscle, Smooth, Vascular; NF-kappa B; Pyridines; Rats; RNA, Messenger; Tumor Necrosis Factor-alpha; Up-Regulation | 2009 |
p38 Mitogen-activated protein kinase is involved in endoplasmic reticulum stress-induced cell death and autophagy in human gingival fibroblasts.
Topics: Autophagy; Brefeldin A; Cell Death; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Fibroblasts; Gingiva; Heat-Shock Proteins; Humans; Imidazoles; Microtubule-Associated Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Synthesis Inhibitors; Pyridines; Thapsigargin; Transcription Factor CHOP; Tunicamycin | 2010 |
Involvement of diacylglycerol kinase γ in modulation of iNOS synthesis in Golgi apparatus of vascular endothelial cells.
Topics: Animals; Aorta, Thoracic; Blotting, Western; Brefeldin A; Diacylglycerol Kinase; Endothelial Cells; Enzyme Inhibitors; Golgi Apparatus; Imidazoles; Immunohistochemistry; Interleukin-1beta; Isoenzymes; Male; Nitric Oxide Synthase Type II; Nocodazole; Piperidines; Protein Synthesis Inhibitors; Pyridines; Quinazolinones; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; RNA, Messenger | 2012 |
Unfolded protein response induced by Brefeldin A increases collagen type I levels in hepatic stellate cells through an IRE1α, p38 MAPK and Smad-dependent pathway.
Topics: Animals; Brefeldin A; Cell Line; Collagen Type I; Endoplasmic Reticulum Stress; Endoribonucleases; Fibrosis; Gene Expression Regulation; Hepatic Stellate Cells; Imidazoles; MAP Kinase Signaling System; Multienzyme Complexes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Pyridines; Rats; RNA, Messenger; Smad3 Protein; Unfolded Protein Response | 2016 |