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sb 203580 and benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone

sb 203580 has been researched along with benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone in 20 studies

Compound Research Comparison

Studies
(sb 203580)
Trials
(sb 203580)
Recent Studies (post-2010)
(sb 203580)
Studies
(benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone)
Trials
(benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone)
Recent Studies (post-2010) (benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone)
3,48941,1371,8970411

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (15.00)18.2507
2000's9 (45.00)29.6817
2010's8 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Biemann, HP; Blenis, J; Davis, RJ; Juo, P; Konz, RF; Kuo, CJ; Raingeaud, J; Reynolds, SE1
Beyaert, R; Carpentier, I; Declercq, W; Fiers, W; Malinin, NL; Wallach, D1
Bushell, M; McKendrick, L; Morley, SJ1
Cohen, GM; Dickens, M; MacFarlane, M1
Lam, CW; Wong, CK; Zhang, JP1
Andreka, P; Bishopric, NH; Dougherty, C; Slepak, TI; Webster, KA; Zang, J1
Arena, S; Benatti, U; Corsaro, A; Damonte, G; Florio, T; Millo, E; Schettini, G; Tagliavini, F; Thellung, S; Villa, V1
Furuhata, M; Mizuguchi, J; Suzuki, J; Takada, E; Toyota, H1
Kim, CH; Kim, JY; Kim, KS; Lee, BJ; Lee, JG; Song, KS; Yoon, JH1
Ayuzawa, R; Eguchi, R; Kaji, K; Miyakaze, S; Ohta, T; Suzuki, A1
Chang, SP; Chao, KC; Chen, YH; Hsu, WL; Li, HY; Sung, YJ; Tsui, KH1
Eguchi, R; Fujimori, Y; Kaji, K; Nakano, T; Ohta, T; Suzuki, A; Toné, S1
Auslender, R; Bitterman, H; Khodalev, O; Lahat, N; Shapiro, S1
Agrawal, M; Bala Bhaskar, AS; Gupta, N; Lakshmana Rao, PV; Ravindran, J1
Furtak, T; Gauthier, ER; Guerin, PJ; Harnett, CC1
Arimura, N; Hisatomi, T; Ishibashi, T; Otsuka, H; Sakamoto, T; Shirasawa, M; Sonoda, S; Terasaki, H; Uchino, E; Yamashita, T1
Cho, SS; Im, HJ; Kim, CS; Kim, DK; Kim, JS; Kim, SG; Lee, SY; Moon, SM; Oh, JS; Park, MR; Yoon, G; You, JS1
Gao, HW; He, YY; Khan, M; Li, YM; Ma, TH; Yang, JB; Yao, M1
Cho, SB; Joo, YE; Lee, WS; Myung, DS; Oh, HH; Park, D; Park, SY; Park, YL; Yu, HM1
Feng, B; Jin, X; Lu, X; Qin, H; Shi, L; Wang, H; Wang, R; Yang, X; Yu, D1

Other Studies

20 other study(ies) available for sb 203580 and benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone

ArticleYear
Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases.
    Molecular and cellular biology, 1997, Volume: 17, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caenorhabditis elegans Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 1; Caspases; Cysteine Endopeptidases; Dactinomycin; Enzyme Activation; Enzyme Inhibitors; Etoposide; fas Receptor; Helminth Proteins; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; MAP Kinase Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Pyridines; Serpins; Signal Transduction; Sorbitol; Transcription, Genetic; Viral Proteins

1997
TRAF2 plays a dual role in NF-kappaB-dependent gene activation by mediating the TNF-induced activation of p38 MAPK and IkappaB kinase pathways.
    FEBS letters, 1998, Mar-27, Volume: 425, Issue:2

    Topics: Amino Acid Chloromethyl Ketones; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Transformed; Cysteine Proteinase Inhibitors; Enzyme Activation; Gene Expression Regulation; HeLa Cells; Humans; I-kappa B Kinase; Imidazoles; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Proteins; Pyridines; Serpins; TNF Receptor-Associated Factor 2; Transcriptional Activation; Tumor Necrosis Factor-alpha; Viral Proteins

1998
Cleavage of translation initiation factor 4G (eIF4G) during anti-Fas IgM-induced apoptosis does not require signalling through the p38 mitogen-activated protein (MAP) kinase.
    FEBS letters, 1998, Oct-30, Volume: 438, Issue:1-2

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Arsenites; Calcium-Calmodulin-Dependent Protein Kinases; Caspase Inhibitors; Cell Survival; Etoposide; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4G; fas Receptor; Humans; Imidazoles; Immunoglobulin M; Jurkat Cells; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Peptide Initiation Factors; Phosphorylation; Poly(A)-Binding Proteins; Protein Biosynthesis; Pyridines; RNA-Binding Proteins; Signal Transduction; Sirolimus

1998
JNK (c-Jun N-terminal kinase) and p38 activation in receptor-mediated and chemically-induced apoptosis of T-cells: differential requirements for caspase activation.
    The Biochemical journal, 2000, May-15, Volume: 348 Pt 1

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; fas Receptor; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Membrane Glycoproteins; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; T-Lymphocytes; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha

2000
Role of caspases in dexamethasone-induced apoptosis and activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase in human eosinophils.
    Clinical and experimental immunology, 2000, Volume: 122, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Anti-Inflammatory Agents; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cells, Cultured; Cysteine Proteinase Inhibitors; Dexamethasone; Enzyme Activation; Enzyme Inhibitors; Eosinophils; Glucocorticoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines

2000
Cytoprotection by Jun kinase during nitric oxide-induced cardiac myocyte apoptosis.
    Circulation research, 2001, Feb-16, Volume: 88, Issue:3

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspase Inhibitors; Caspases; Cells, Cultured; Cyclic GMP; Cysteine Proteinase Inhibitors; DNA Fragmentation; DNA, Recombinant; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glutathione; Imidazoles; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Myocardium; Nitric Oxide; Nitroso Compounds; Plasmids; Protein Serine-Threonine Kinases; Pyridines; S-Nitrosoglutathione; Transfection

2001
p38 MAP kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells.
    Neurobiology of disease, 2002, Volume: 9, Issue:1

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Caspases; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Neuroblastoma; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Prion Diseases; Prions; Pyridines; Tumor Cells, Cultured

2002
Requirement of c-Jun N terminal kinase and P38 mitogen-activated protein kinase for anti-IgM-induced reduction in mitochondrial membrane potential in CH31 B lymphoma cells.
    Immunology letters, 2002, Apr-22, Volume: 81, Issue:2

    Topics: Amino Acid Chloromethyl Ketones; B-Lymphocytes; Caspase Inhibitors; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Imidazoles; Immunoglobulin M; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Lymphoma, B-Cell; Membrane Potentials; Mitochondria; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Tumor Cells, Cultured

2002
Sulindac sulfide-induced apoptosis in sinonasal cancer cells.
    Acta oto-laryngologica, 2005, Volume: 125, Issue:2

    Topics: Amino Acid Chloromethyl Ketones; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma, Squamous Cell; Caspase Inhibitors; Flavonoids; Fluorescence; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Paranasal Sinus Neoplasms; Pyridines; Signal Transduction; Sulindac

2005
Hypoxia-induced apoptosis and tube breakdown are regulated by p38 MAPK but not by caspase cascade in an in vitro capillary model composed of human endothelial cells.
    Journal of cellular physiology, 2007, Volume: 211, Issue:3

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Capillaries; Caspase 3; Caspase Inhibitors; Cell Nucleus; Cells, Cultured; Cysteine Proteinase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Humans; Hypoxia; Imidazoles; In Vitro Techniques; Myocardial Ischemia; p38 Mitogen-Activated Protein Kinases; Pyridines; Signal Transduction; Umbilical Veins

2007
Anti-fas activating antibody enhances trophoblast outgrowth on endometrial epithelial cells by induction of P38 MAPK/JNK-mediated apoptosis.
    Placenta, 2008, Volume: 29, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Anthracenes; Antibodies, Monoclonal; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; Coculture Techniques; Cysteine Proteinase Inhibitors; Embryo Implantation; Endometrium; Epithelial Cells; fas Receptor; Female; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Trophoblasts

2008
Possible involvement of caspase-6 and -7 but not caspase-3 in the regulation of hypoxia-induced apoptosis in tube-forming endothelial cells.
    Experimental cell research, 2009, Jan-15, Volume: 315, Issue:2

    Topics: Actins; Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Caspase 6; Caspase 7; Caspase 9; Caspase Inhibitors; Cell Hypoxia; Cell Line; Cell Nucleus; Chromatin; Cysteine Proteinase Inhibitors; DNA Breaks; DNA Breaks, Double-Stranded; Endothelial Cells; Humans; Imidazoles; Lamin Type A; Models, Biological; Neovascularization, Physiologic; Oligopeptides; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Pyridines

2009
Different activation forms of MMP-2 oppositely affect the fate of endothelial cells.
    American journal of physiology. Cell physiology, 2010, Volume: 298, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Caspase Inhibitors; Cell Movement; Cell Shape; Cells, Cultured; Endothelial Cells; Enzyme Inhibitors; Extracellular Matrix; Humans; Imidazoles; Matrix Metalloproteinase 2; p38 Mitogen-Activated Protein Kinases; Pyridines; Signal Transduction

2010
Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.
    Apoptosis : an international journal on programmed cell death, 2011, Volume: 16, Issue:2

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Anthracenes; Apoptosis; Apoptosis Inducing Factor; Blotting, Western; Caspase 3; Caspase 7; Caspase 9; Cell Line, Tumor; Cyclosporins; Cytochromes c; DNA Damage; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glutathione; Humans; Imidazoles; Immunoblotting; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Pyridines; Reactive Oxygen Species; U937 Cells

2011
Control of late apoptotic events by the p38 stress kinase in L-glutamine-deprived mouse hybridoma cells.
    Cell biochemistry and function, 2013, Volume: 31, Issue:5

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; bcl-X Protein; Caspase Inhibitors; Enzyme Activation; Gene Expression Regulation; Glutamine; Hybridomas; Imidazoles; Mice; Mitochondria; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Signal Transduction

2013
TNF-α disrupts morphologic and functional barrier properties of polarized retinal pigment epithelium.
    Experimental eye research, 2013, Volume: 110

    Topics: Amino Acid Chloromethyl Ketones; Animals; Anthracenes; Blood-Retinal Barrier; Blotting, Western; Cell Polarity; Cells, Cultured; Electric Impedance; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Imidazoles; In Situ Nick-End Labeling; Microscopy, Electron, Scanning; p38 Mitogen-Activated Protein Kinases; Pyridines; Recombinant Proteins; Retinal Pigment Epithelium; Swine; Tight Junction Proteins; Tight Junctions; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2013
Licochalcone A induces apoptosis in KB human oral cancer cells via a caspase-dependent FasL signaling pathway.
    Oncology reports, 2014, Volume: 31, Issue:2

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Caspase 8; Caspase Inhibitors; Cell Line, Tumor; Cell Survival; Chalcones; Chromatin; DNA Fragmentation; Extracellular Signal-Regulated MAP Kinases; Fas Ligand Protein; Flavonoids; Humans; Imidazoles; KB Cells; Keratinocytes; Mouth Neoplasms; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Pyridines; Signal Transduction

2014
Tubeimoside-1 induces oxidative stress-mediated apoptosis and G0/G1 phase arrest in human prostate carcinoma cells in vitro.
    Acta pharmacologica Sinica, 2016, Volume: 37, Issue:7

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Anthracenes; Apoptosis; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Cinnamates; Cyclin E; Cyclin-Dependent Kinase 2; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; G1 Phase; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase Kinase 5; Membrane Potential, Mitochondrial; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Pyridines; Reactive Oxygen Species; Resting Phase, Cell Cycle; Saponins; Thiourea; Triterpenes

2016
Malformin A1 treatment alters invasive and oncogenic phenotypes of human colorectal cancer cells through stimulation of the p38 signaling pathway.
    International journal of oncology, 2017, Volume: 51, Issue:3

    Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Survival; Colorectal Neoplasms; DNA Fragmentation; Humans; Imidazoles; MAP Kinase Signaling System; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Peptides, Cyclic; Phosphorylation; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Pyridines; Tumor Suppressor Protein p53; X-Linked Inhibitor of Apoptosis Protein

2017
The natural phenolic peperobtusin A induces apoptosis of lymphoma U937 cells via the Caspase dependent and p38 MAPK signaling pathways.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 102

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Apoptosis; bcl-2-Associated X Protein; Caspases; Cell Cycle Checkpoints; Cell Proliferation; Cell Survival; Chromans; Humans; Imidazoles; Lymphoma; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Reactive Oxygen Species; U937 Cells

2018