Compounds > sb 203580
Page last updated: 2024-09-05

sb 203580 and bay 11-7085

sb 203580 has been researched along with bay 11-7085 in 7 studies

Compound Research Comparison

Studies
(sb 203580)		Trials
(sb 203580)		Recent Studies (post-2010)
(sb 203580)		Studies
(bay 11-7085)		Trials
(bay 11-7085)		Recent Studies (post-2010) (bay 11-7085)
3,48941,137125050

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)bay 11-7085 (IC50)
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 20.84
D(1A) dopamine receptorHomo sapiens (human)4.412
D(3) dopamine receptorHomo sapiens (human)3.46
C-C chemokine receptor type 2Homo sapiens (human)4.177

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (57.14)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Babbin, BA; Bryington, M; Dangsupa, A; Hu, X; Janssen, WE; Moscinski, LC; Rezai-Zadeh, N; Zuckerman, KS1
Baizabal-Aguirre, VM; Barriga-Rivera, JG; Bravo-Patiño, A; Cajero-Juárez, M; Cárabez-Trejo, A; Oviedo-Boyso, J; Valdez-Alarcón, JJ1
Baizabal-Aguirre, VM; Bravo-Patiño, A; Cajero-Juárez, M; Oviedo-Boyso, J; Valdez-Alarcón, JJ1
Botez, GM; Sima, AV; Simionescu, M; Stancu, CS; Toma, L1
Chung, SW; Hwang, N; Kang, YH; Kwon, MY; Shin, DY; Woo, JM1
Chen, Y; Dai, SM; He, ZW; Qin, YH; Shen, Q; Wang, ZW1
Lee, CS; Nam, YJ1

Other Studies

7 other study(ies) available for sb 203580 and bay 11-7085

ArticleYear
An IkappaBalpha inhibitor causes leukemia cell death through a p38 MAP kinase-dependent, NF-kappaB-independent mechanism.
    Cancer research, 2001, Aug-15, Volume: 61, Issue:16

    Topics: Activating Transcription Factor 2; Anti-Infective Agents; Apoptosis; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; I-kappa B Proteins; Imidazoles; Leukemia, Myeloid; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinases; Necrosis; NF-kappa B; NF-KappaB Inhibitor alpha; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Sulfones; Transcription Factors; Tumor Cells, Cultured; U937 Cells

2001
Internalization of Staphylococcus aureus by bovine endothelial cells is associated with the activity state of NF-kappaB and modulated by the pro-inflammatory cytokines TNF-alpha and IL-1beta.
    Scandinavian journal of immunology, 2008, Volume: 67, Issue:2

    Topics: Animals; Anthracenes; Cattle; Colony Count, Microbial; Endothelial Cells; Enzyme Inhibitors; Female; Imidazoles; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Mastitis, Bovine; Microscopy, Electron; NF-kappa B; Nitriles; Peptides; Pyridines; Staphylococcal Infections; Staphylococcus aureus; Sulfones; Tumor Necrosis Factor-alpha

2008
TNF-alpha reduces the level of Staphylococcus epidermidis internalization by bovine endothelial cells.
    FEMS microbiology letters, 2009, Volume: 292, Issue:1

    Topics: Animals; Anthracenes; Cattle; Colony Count, Microbial; Cytoplasm; Endothelial Cells; Imidazoles; Immunologic Factors; MAP Kinase Kinase 4; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Peptides; Pyridines; Staphylococcus epidermidis; Sulfones; Tumor Necrosis Factor-alpha

2009
Irreversibly glycated LDL induce oxidative and inflammatory state in human endothelial cells; added effect of high glucose.
    Biochemical and biophysical research communications, 2009, Dec-18, Volume: 390, Issue:3

    Topics: Cell Line; Cell Proliferation; Chemokine CCL2; Endothelium, Vascular; Gene Expression; Glucose; Glycation End Products, Advanced; Humans; Hyperglycemia; Imidazoles; Inflammation; Lipoproteins, LDL; NADPH Oxidase 4; NADPH Oxidases; Nitriles; Pyridines; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Sulfones

2009
Human retinal pigment epithelial cells express the long pentraxin PTX3.
    Molecular vision, 2013, Volume: 19

    Topics: Anthracenes; Butadienes; C-Reactive Protein; Cell Line; Cytokines; Gene Expression; Humans; Imidazoles; Inflammation Mediators; Interferon-gamma; Interleukin-1beta; MAP Kinase Signaling System; NF-kappa B; Nitriles; Pyridines; Retinal Pigment Epithelium; RNA, Messenger; Serum Amyloid P-Component; Signal Transduction; Sulfones; Tumor Necrosis Factor-alpha

2013
HMGB1 acts in synergy with lipopolysaccharide in activating rheumatoid synovial fibroblasts via p38 MAPK and NF-κB signaling pathways.
    Mediators of inflammation, 2013, Volume: 2013

    Topics: Adult; Aged; Arthritis, Rheumatoid; Cell Proliferation; Fibroblasts; Gene Expression Regulation; HMGB1 Protein; Humans; Imidazoles; Interleukin-6; Lipopolysaccharides; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; Middle Aged; NF-kappa B p50 Subunit; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Messenger; Signal Transduction; Sulfones; Synovial Membrane; Toll-Like Receptor 4

2013
Protocatechuic acid inhibits Toll-like receptor-4-dependent activation of NF-κB by suppressing activation of the Akt, mTOR, JNK and p38-MAPK.
    International immunopharmacology, 2018, Volume: 55

    Topics: Acetylcysteine; Anthracenes; Anti-Inflammatory Agents; Cell Line, Transformed; Cytokines; Humans; Hydroxybenzoates; Imidazoles; Keratinocytes; Lipopolysaccharides; MAP Kinase Kinase 4; Nitriles; Oncogene Protein v-akt; p38 Mitogen-Activated Protein Kinases; Pyridines; Signal Transduction; Sulfones; TOR Serine-Threonine Kinases

2018