Page last updated: 2024-09-05

sb 203580 and bay 11-7082

sb 203580 has been researched along with bay 11-7082 in 36 studies

Compound Research Comparison

Studies (sb 203580)	Trials (sb 203580)	Recent Studies (post-2010) (sb 203580)	Studies (bay 11-7082)	Trials (bay 11-7082)	Recent Studies (post-2010) (bay 11-7082)
3,489	4	1,137	570	1	383

Protein Interaction Comparison

Protein	Taxonomy	bay 11-7082 (IC50)
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	0.82
Nuclear factor NF-kappa-B p105 subunit	Homo sapiens (human)	2
Nuclear factor NF-kappa-B p100 subunit	Homo sapiens (human)	2
Transcription factor p65	Homo sapiens (human)	2.5

Research

Studies (36)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	14 (38.89)	29.6817
2010's	19 (52.78)	24.3611
2020's	3 (8.33)	2.80

Authors

Authors	Studies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H	1
Kato, E; Sasaki, Y; Takahashi, N	1
Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A	1
Chokchaisiri, R; Chuprajob, T; Lin, Y; Lu, X; Shen, X; Sornkaew, N; Suksamrarn, A; Wang, F; Wang, P; Wongkrajang, K; Yang, L; Yang, N; Zhang, G; Zhou, Z	1
Chi, DS; Fitzgerald, SM; Hall, HK; Krishnaswamy, G; Lee, SA	1
Ip, WK; Lam, CW; Tian, YP; Wang, CB; Wong, CK	1
Cheung, PF; Ip, WK; Lam, CW; Wong, CK	1
Balakrishnan, A; Malladi, V; Puthenedam, M; Williams, PH	1
Khatri, M; Sharma, JM	1
Beales, IL; Ogunwobi, OO	1
Bae, YS; Baek, SH; Jo, EJ; Jo, SH; Kim, MK; Kim, SD; Lee, C; Lee, HY; Lee, YN; Park, KS; Shin, EH	1
Ip, WK; Lam, CW; Li, ML; Tian, YP; Wang, CB; Wong, CK	1
Alexis, NE; Bromberg, PA; Chen, X; Peden, DB; Wu, W	1
Guo, JH; Wu, ZL; Xiong, Y; Zhao, YT; Zhou, WL	1
An, L; Han, Y; Li, W; Niu, M	1
Huang, W; Li, JJ; Liang, XT; Liu, WL; Pan, K; Sun, JC; Wang, H; Weng, DS; Xia, JC; Zhang, HK; Zhou, J	1
Chen, HM; Cheng, SJ; Chiang, CP; Deng, YT; Kuo, MY	1
Raddatzc, D; Ramadori, G; Sunil, Y	1
He, SZ; Jian, CX; Li, CJ; Liu, XC; Liu, XF	1
Haar, L; Huber, N; Noel, G; Ogle, CK; Pritts, TA; Shan, Y; Wang, Q	1
Chen, M; Hu, DN; Li, SS; Yao, L	1
Baumgrass, R; Frischbutter, S; Pätzel, M; Radbruch, A; Schultheis, K	1
Cooper, PR; He, W; Huang, P; Smith, AJ; Wang, ZH; Yu, Q; Zhang, J; Zhu, QL	1
Cui, B; Gao, X; Jiao, Y; Sun, W; Xia, Y; Zhao, Y	1
Hou, YQ; Huang, L; Li, QH; Wang, J; Xu, K; Xu, P	1
Cao, J; Fang, L; Fu, J; Ge, D; Li, X; Liu, Z; Ran, J; Ran, Y; Shi, Q; Wang, L; Zhang, H; Zhao, H; Zheng, X; Zhou, Y	1
Gao, FG; Huang, XB; Jiang, YN; Ke, SZ; Li, J; Wang, YN; Yan, HQ; Zhang, YH	1
Geng, M; Holmdahl, R; Jiang, C; Lu, S; Ma, J; Meng, L; Sun, J; Wu, X; Xu, J; Zhu, W	1
Chen, W; Dai, J; Gao, F; Guo, J; Li, K; Sheng, J; Wang, G; Zhao, X	1
Wang, W; Wu, L; Yu, G; Zhang, X; Zhao, X	1
Cao, J; Fan, Y; Gao, L; Wang, C; Wang, Y; Xie, Y; Xu, Z; Yin, Z	1
Arumugam, TV; Baik, SH; Chen, CL; Cheng, YL; Chunduri, P; Dheen, ST; Drummond, GR; Fann, DY; Jo, DG; Lim, YA; Lok, KZ; Sobey, CG	1
Guo, JJ; Guo, Y; Li, XL; Qiu, LH; Yang, D; Yu, YQ	1
Jiang, Y; Mu, F; Wu, H; You, Q; Zhang, N	1
Gong, SJ; Hu, YY; Li, WB; Sun, YW; Xian, XH; Zhang, JG; Zhang, LY; Zhang, M	1
Bhavan, PS; Chung, CL; Hou, SM; Hsia, CH; Hsia, CW; Huang, WC; Jayakumar, T; Sheu, JR; Wu, MP	1

Other Studies

36 other study(ies) available for sb 203580 and bay 11-7082

Article	Year
Identifying off-target effects and hidden phenotypes of drugs in human cells. Nature chemical biology, 2006, Volume: 2, Issue:6 Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship	2006
Sodium dl-α-tocopheryl-6-O-phosphate inhibits PGE₂ production in keratinocytes induced by UVB, IL-1β and peroxidants. Bioorganic & medicinal chemistry, 2011, Nov-01, Volume: 19, Issue:21 Topics: alpha-Tocopherol; Anti-Inflammatory Agents; Blotting, Western; Cyclooxygenase 2; Dinoprostone; Humans; In Vitro Techniques; Interleukin-1beta; Keratinocytes; Oxidants; p38 Mitogen-Activated Protein Kinases; Radiation-Protective Agents; Real-Time Polymerase Chain Reaction; RNA, Messenger; Skin; Ultraviolet Rays	2011
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery. The Biochemical journal, 2013, Apr-15, Volume: 451, Issue:2 Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase	2013
Discovery of diarylheptanoids that activate α7 nAchR-JAK2-STAT3 signaling in macrophages with anti-inflammatory activity in vitro and in vivo. Bioorganic & medicinal chemistry, 2022, 07-15, Volume: 66 Topics: Animals; Anti-Inflammatory Agents; Diarylheptanoids; Janus Kinase 2; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Sepsis; STAT3 Transcription Factor	2022
Human lung fibroblasts express interleukin-6 in response to signaling after mast cell contact. American journal of respiratory cell and molecular biology, 2004, Volume: 30, Issue:4 Topics: Anti-Inflammatory Agents; Cells, Cultured; Coculture Techniques; Dexamethasone; Enzyme Inhibitors; Fibroblasts; Humans; Imidazoles; Interleukin-6; Lung; Mast Cells; Mitogen-Activated Protein Kinases; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyridines; Signal Transduction; Sulfones	2004
Role of p38 MAPK and NF-kB for chemokine release in coculture of human eosinophils and bronchial epithelial cells. Clinical and experimental immunology, 2005, Volume: 139, Issue:1 Topics: Bronchi; Cells, Cultured; Chemokine CCL2; Chemokine CCL5; Chemokine CXCL10; Chemokine CXCL9; Chemokines; Chemokines, CXC; Coculture Techniques; Enzyme Inhibitors; Eosinophils; Epithelial Cells; Fixatives; Formaldehyde; Gene Expression Regulation; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Interleukin-8; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Polymers; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Sulfones	2005
Interleukin-25-induced chemokines and interleukin-6 release from eosinophils is mediated by p38 mitogen-activated protein kinase, c-Jun N-terminal kinase, and nuclear factor-kappaB. American journal of respiratory cell and molecular biology, 2005, Volume: 33, Issue:2 Topics: Anthracenes; Base Sequence; Chemokines; DNA, Complementary; Eosinophils; Humans; Imidazoles; In Vitro Techniques; Intercellular Adhesion Molecule-1; Interleukin-17; Interleukin-6; Interleukins; JNK Mitogen-Activated Protein Kinases; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptors, Interleukin; Recombinant Proteins; Sulfones	2005
Enteropathogenic Escherichia coli outer membrane proteins induce iNOS by activation of NF-kappaB and MAP kinases. Inflammation, 2004, Volume: 28, Issue:6 Topics: Bacterial Outer Membrane Proteins; Caco-2 Cells; Electrophoretic Mobility Shift Assay; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Escherichia coli; Flavonoids; Humans; Imidazoles; Luminescent Measurements; Mitogen-Activated Protein Kinases; NF-kappa B; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitriles; Nitrites; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfones	2004
Infectious bursal disease virus infection induces macrophage activation via p38 MAPK and NF-kappaB pathways. Virus research, 2006, Volume: 118, Issue:1-2 Topics: Animals; Cells, Cultured; Chickens; Cyclooxygenase 2; Enzyme Inhibitors; Gene Expression Regulation; Imidazoles; Immunohistochemistry; Infectious bursal disease virus; Interleukin-8; Macrophage Activation; Macrophages; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfones	2006
Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells. Regulatory peptides, 2006, May-15, Volume: 134, Issue:2-3 Topics: Adiponectin; Cell Proliferation; Chemokine CCL2; Cytokines; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Granulocyte-Macrophage Colony-Stimulating Factor; HT29 Cells; Humans; Imidazoles; Indoles; Interleukin-1; Interleukin-8; Intestinal Mucosa; Isoquinolines; Maleimides; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Sulfonamides; Sulfones	2006
Serum amyloid A induces contrary immune responses via formyl peptide receptor-like 1 in human monocytes. Molecular pharmacology, 2006, Volume: 70, Issue:1 Topics: Animals; Blotting, Western; Cell Line, Tumor; Chromones; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; Interleukin-10; Monocytes; Morpholines; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pyridines; Receptors, Formyl Peptide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serum Amyloid A Protein; Sulfones; Tumor Necrosis Factor-alpha	2006
House dust mite allergen Der p 1 elevates the release of inflammatory cytokines and expression of adhesion molecules in co-culture of human eosinophils and bronchial epithelial cells. International immunology, 2006, Volume: 18, Issue:8 Topics: Antigens, Dermatophagoides; Arthropod Proteins; Asthma; Bronchi; Cell Adhesion Molecules; Coculture Techniques; Curcumin; Cysteine Endopeptidases; Cytokines; Dermatophagoides pteronyssinus; Enzyme Activation; Eosinophils; Epithelial Cells; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyroglyphidae; Sulfones; Th2 Cells; Transcription Factor AP-1	2006
Involvement of mitogen-activated protein kinases and NFkappaB in LPS-induced CD40 expression on human monocytic cells. Toxicology and applied pharmacology, 2008, Apr-15, Volume: 228, Issue:2 Topics: Animals; Anthracenes; Butadienes; CD40 Antigens; Cell Line; Cell Line, Tumor; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Flow Cytometry; Humans; Imidazoles; Immunoblotting; Leupeptins; Mitogen-Activated Protein Kinases; Monocytes; NF-kappa B; Nitriles; Phosphorylation; Polysaccharides, Bacterial; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Sulfones; Time Factors; Toll-Like Receptor 4	2008
Innate immune responses of epididymal epithelial cells to Staphylococcus aureus infection. Immunology letters, 2008, Aug-15, Volume: 119, Issue:1-2 Topics: Animals; Cell Culture Techniques; Epididymis; Epithelial Cells; Gene Expression Regulation; Genital Diseases, Male; Imidazoles; Immunity, Innate; Interleukin-1beta; Intracellular Signaling Peptides and Proteins; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Nitriles; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Staphylococcal Infections; Staphylococcus aureus; Sulfones; Tumor Necrosis Factor-alpha	2008
Upregulation of proinflammatory cytokines and NO production in BV-activated avian macrophage-like cell line (HD11) requires MAPK and NF-kappaB pathways. International immunopharmacology, 2009, Volume: 9, Issue:7-8 Topics: Animals; Anthracenes; Birds; Cell Line; DNA Virus Infections; Imidazoles; Immunity, Innate; Interferon-gamma; Interleukin-12 Subunit p40; Macrophage Activation; Macrophages; MAP Kinase Kinase 4; MAP Kinase Signaling System; Moths; Nitric Oxide; Nitriles; Nucleopolyhedroviruses; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Sulfones; Virulence	2009
The pivotal role of p38 and NF-kappaB signal pathways in the maturation of human monocyte-derived dendritic cells stimulated by streptococcal agent OK-432. Immunobiology, 2009, Volume: 214, Issue:5 Topics: B7-1 Antigen; Cell Differentiation; Cells, Cultured; Chemokine CXCL10; Dendritic Cells; Humans; Imidazoles; Interleukin-12; Lymphocyte Activation; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Picibanil; Pyridines; Signal Transduction; Streptococcus; Sulfones; T-Lymphocytes; Tumor Necrosis Factor-alpha	2009
Arecoline-stimulated connective tissue growth factor production in human buccal mucosal fibroblasts: Modulation by curcumin. Oral oncology, 2009, Volume: 45, Issue:9 Topics: Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Arecoline; Cheek; Cholinergic Agonists; Connective Tissue Growth Factor; Curcumin; Endothelial Cells; Epithelial Cells; Fibroblasts; Flavonoids; Humans; Imidazoles; Mouth Mucosa; Nitriles; Oral Submucous Fibrosis; Pyridines; Sulfones	2009
Influence of NFkappaB inhibitors on IL-1beta-induced chemokine CXCL8 and -10 expression levels in intestinal epithelial cell lines: glucocorticoid ineffectiveness and paradoxical effect of PDTC. International journal of colorectal disease, 2010, Volume: 25, Issue:3 Topics: Caco-2 Cells; Chemokine CXCL10; Dexamethasone; Epithelial Cells; Flavonoids; Gene Expression Regulation, Neoplastic; Genes, Reporter; Glucocorticoids; HT29 Cells; Humans; Imidazoles; Interleukin-1beta; Interleukin-8; Intestines; NF-kappa B; Nitriles; Pyridines; Pyrrolidines; Receptors, Glucocorticoid; RNA, Messenger; Sulfones; Thiocarbamates	2010
IL-33 is induced by amyloid-β stimulation and regulates inflammatory cytokine production in retinal pigment epithelium cells. Inflammation, 2012, Volume: 35, Issue:2 Topics: Amyloid beta-Peptides; Anthracenes; Butadienes; Cell Line; Humans; Imidazoles; Inflammation; Interleukin-1 Receptor-Like 1 Protein; Interleukin-1beta; Interleukin-33; Interleukin-6; Interleukin-8; Interleukins; JNK Mitogen-Activated Protein Kinases; Macular Degeneration; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Nitriles; Peptide Fragments; Pyridines; Receptors, Cell Surface; Retinal Pigment Epithelium; Sulfones; Tumor Necrosis Factor-alpha	2012
NF-κΒ inhibition is ineffective in blocking cytokine-induced IL-8 production but P38 and STAT1 inhibitors are effective. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2012, Volume: 61, Issue:9 Topics: Caco-2 Cells; Catechin; Cell Line; Cytokines; Genes, Reporter; Humans; Imidazoles; NF-kappa B; Nitric Oxide; Nitriles; p38 Mitogen-Activated Protein Kinases; Proline; Protein Kinase Inhibitors; Pyridines; STAT1 Transcription Factor; Sulfones; Thiocarbamates	2012
Subtoxic levels hydrogen peroxide-induced expression of interleukin-6 by epidermal melanocytes. Archives of dermatological research, 2012, Volume: 304, Issue:10 Topics: Anthracenes; Cells, Cultured; Epidermis; Extracellular Signal-Regulated MAP Kinases; Humans; Hydrogen Peroxide; Imidazoles; Interleukin-6; Melanocytes; NF-kappa B; Nitriles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyridines; Sulfones; Up-Regulation; Vitiligo	2012
Evaluation of calcineurin/NFAT inhibitor selectivity in primary human Th cells using bar-coding and phospho-flow cytometry. Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2012, Volume: 81, Issue:11 Topics: Arachidonic Acids; Calcineurin Inhibitors; Drug Evaluation, Preclinical; Electronic Data Processing; Flow Cytometry; Fluorescence; Genes, Reporter; Humans; Imidazoles; Inhibitory Concentration 50; MAP Kinase Signaling System; NFATC Transcription Factors; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Sulfones; T-Lymphocytes, Helper-Inducer; Transcription Factor RelA	2012
CpG ODN-induced matrix metalloproteinase-13 expression is mediated via activation of the ERK and NF-κB signalling pathways in odontoblast cells. International endodontic journal, 2013, Volume: 46, Issue:7 Topics: Animals; Anthracenes; Cell Line; Chloroquine; CpG Islands; Dental Pulp; Extracellular Signal-Regulated MAP Kinases; I-kappa B Proteins; Imidazoles; MAP Kinase Signaling System; Matrix Metalloproteinase 13; Mice; Mitogen-Activated Protein Kinases; Myeloid Differentiation Factor 88; NF-kappa B; Nitriles; Odontoblasts; Oligodeoxyribonucleotides; Phosphorylation; Pyridines; Pyrrolidines; Real-Time Polymerase Chain Reaction; Signal Transduction; Sulfones; Thiocarbamates; Toll-Like Receptor 9; Tosylphenylalanyl Chloromethyl Ketone; Transcription Factor RelA	2013
Immune complexes activate human endothelium involving the cell-signaling HMGB1-RAGE axis in the pathogenesis of lupus vasculitis. Laboratory investigation; a journal of technical methods and pathology, 2013, Volume: 93, Issue:6 Topics: Antigen-Antibody Complex; Cell Survival; Cytokines; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Flavonoids; HMGB1 Protein; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Lupus Vasculitis, Central Nervous System; Monocytes; Nitriles; Pyridines; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Signal Transduction; Sulfones; Transcription Factor RelA; Transendothelial and Transepithelial Migration; U937 Cells; Up-Regulation; Vascular Cell Adhesion Molecule-1	2013
Pancreatitis-associated ascitic fluid induces proinflammatory cytokine expression in THP-1 cells by inhibiting anti-inflammatory signaling. Pancreas, 2013, Volume: 42, Issue:5 Topics: Acute Disease; Apoptosis; Ascitic Fluid; Blotting, Western; Cell Line, Tumor; Cell Survival; Culture Media; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression; Humans; Imidazoles; Inflammation Mediators; Interleukin-6; Leukemia, Monocytic, Acute; Nitriles; p38 Mitogen-Activated Protein Kinases; Pancreatitis; Phosphorylation; PPAR gamma; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sulfones; Transcription Factor RelA; Tumor Necrosis Factor-alpha	2013
Geniposide suppresses LPS-induced nitric oxide, PGE2 and inflammatory cytokine by downregulating NF-κB, MAPK and AP-1 signaling pathways in macrophages. International immunopharmacology, 2014, Volume: 20, Issue:2 Topics: Animals; Anti-Inflammatory Agents; Butadienes; Cell Line; Cyclooxygenase 2; Dinoprostone; Extracellular Signal-Regulated MAP Kinases; Gardenia; Imidazoles; Inflammation Mediators; Interleukin-6; Iridoids; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred Strains; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Nitriles; Pyridines; Signal Transduction; Sulfones; Transcription Factor AP-1; Tumor Necrosis Factor-alpha	2014
Interleukin 6 augments lung cancer chemotherapeutic resistance via ataxia-telangiectasia mutated/NF-kappaB pathway activation. Cancer science, 2014, Volume: 105, Issue:9 Topics: Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; bcl-X Protein; Camptothecin; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Interleukin-6; Lung Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Pyridines; Sulfones	2014
Pristane primed rat T cells enhance TLR3 expression of fibroblast-like synoviocytes via TNF-α initiated p38 MAPK and NF-κB pathways. Clinical immunology (Orlando, Fla.), 2015, Volume: 156, Issue:2 Topics: Animals; Arthritis, Experimental; CD4-Positive T-Lymphocytes; Cell Line; Culture Media, Conditioned; Enzyme Inhibitors; Humans; Imidazoles; Immunosuppressive Agents; Interferon-gamma; Interleukin-17; Interleukin-6; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; RNA, Messenger; Sulfones; Synovial Membrane; Terpenes; Toll-Like Receptor 3; Tumor Necrosis Factor-alpha; Up-Regulation	2015
Tumor necrosis factor-α enhances voltage-gated Na⁺ currents in primary culture of mouse cortical neurons. Journal of neuroinflammation, 2015, Jun-26, Volume: 12 Topics: Action Potentials; Animals; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Imidazoles; Mice; Mice, Inbred C57BL; Models, Animal; Neurons; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Pyridines; Signal Transduction; Sulfones; Time Factors; Tumor Necrosis Factor-alpha; Voltage-Gated Sodium Channels	2015
Anti-HBV activity and mechanism of marine-derived polyguluronate sulfate (PGS) in vitro. Carbohydrate polymers, 2016, Jun-05, Volume: 143 Topics: Antiviral Agents; Aquatic Organisms; Butadienes; DNA Replication; DNA, Viral; Hep G2 Cells; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Imidazoles; Interferon-beta; Lamivudine; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Polysaccharides; Protein Kinase Inhibitors; Pyridines; RNA, Viral; Sulfones; Virus Replication	2016
Artemisinin inhibits monocyte adhesion to HUVECs through the NF-κB and MAPK pathways in vitro. International journal of molecular medicine, 2016, Volume: 37, Issue:6 Topics: Anti-Inflammatory Agents; Artemisinins; Butadienes; Cell Adhesion; Cell Line; Coculture Techniques; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Intercellular Adhesion Molecule-1; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Monocytes; NF-kappa B; Nitriles; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Sulfones; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1	2016
Evidence that NF-κB and MAPK Signaling Promotes NLRP Inflammasome Activation in Neurons Following Ischemic Stroke. Molecular neurobiology, 2018, Volume: 55, Issue:2 Topics: Adaptor Proteins, Signal Transducing; Animals; Anthracenes; Apoptosis Regulatory Proteins; Brain; Brain Ischemia; Butadienes; Extracellular Signal-Regulated MAP Kinases; Imidazoles; Inflammasomes; Mice; Neurons; NF-kappa B; Nitriles; NLR Family, Pyrin Domain-Containing 3 Protein; Pyridines; Signal Transduction; Stroke; Sulfones	2018
[Effect of lipopolysaccharides from Porphyromonas endodontalis on the expression of interleukin-34 in mouse osteoblasts]. Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2017, Volume: 26, Issue:1 Topics: Animals; Carbazoles; Imidazoles; Interleukin-6; Interleukins; Lipopolysaccharides; Mice; NF-kappa B; Nitriles; Osteoblasts; Porphyromonas endodontalis; Pyridines; RNA, Messenger; Signal Transduction; Sulfones	2017
Gentiopicrin exerts anti-rheumatic effect in human fibroblast-like synoviocytes via inhibition of p38MAPK/NF-κB pathway. Cellular and molecular biology (Noisy-le-Grand, France), 2019, Aug-05, Volume: 65, Issue:6 Topics: Arthritis, Rheumatoid; Cell Survival; Cells, Cultured; Fibroblasts; Humans; Imidazoles; Interleukin-1beta; Interleukin-6; Iridoid Glucosides; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Plant Extracts; Pyridines; RNA, Messenger; Signal Transduction; Sulfones; Synoviocytes; Transcription Factor RelA; Tumor Necrosis Factor-alpha	2019
The p38 MAPK/NF-κB pathway mediates GLT-1 up-regulation during cerebral ischemic preconditioning-induced brain ischemic tolerance in rats. Brain research bulletin, 2021, Volume: 175 Topics: Animals; Brain Ischemia; CA1 Region, Hippocampal; Excitatory Amino Acid Transporter 2; Imidazoles; Ischemic Preconditioning; Kainic Acid; Male; MAP Kinase Signaling System; Neuroprotection; NF-kappa B; NF-kappa B p50 Subunit; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Wistar; Sulfones; Transcription Factor RelA	2021
Decreased Human Platelet Activation and Mouse Pulmonary Thrombosis by Rutaecarpine and Comparison of the Relative Effectiveness with BAY11-7082: Crucial Signals of p38-NF-κB. Molecules (Basel, Switzerland), 2022, Jan-12, Volume: 27, Issue:2 Topics: Animals; Disease Models, Animal; Fibrinolytic Agents; Free Radical Scavengers; Free Radicals; Humans; I-kappa B Kinase; Imidazoles; Indole Alkaloids; Male; Mice, Inbred ICR; NF-kappa B; Nitriles; P-Selectin; p38 Mitogen-Activated Protein Kinases; Platelet Activation; Protein Kinase Inhibitors; Pulmonary Embolism; Pyridines; Quinazolines; Sulfones; Thrombosis; Transcription Factor RelA	2022