sb 203580 has been researched along with anisomycin in 72 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (anisomycin) | Trials (anisomycin) | Recent Studies (post-2010) (anisomycin) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 1,357 | 0 | 319 |
| Protein | Taxonomy | sb 203580 (IC50) | anisomycin (IC50) |
|---|---|---|---|
| Glucose transporter | Leishmania mexicana | 0.225 | |
| Hexose transporter 1 | Plasmodium falciparum (malaria parasite P. falciparum) | 0.326 | |
| Solute carrier family 2, facilitated glucose transporter member 1 | Homo sapiens (human) | 0.321 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (18.06) | 18.2507 |
| 2000's | 44 (61.11) | 29.6817 |
| 2010's | 14 (19.44) | 24.3611 |
| 2020's | 1 (1.39) | 2.80 |
| Authors | Studies |
|---|---|
| Cohen, P; Cuenda, A; Gould, GW; Thomson, FJ | 1 |
| Barratt, MJ; Cano, E; Cohen, P; Cuenda, A; Hazzalin, CA; Mahadevan, LC | 1 |
| Bokemeyer, D; Dunn, MJ; Sorokin, A | 1 |
| Cohen, MV; Downey, JM; Liu, GS; Weinbrenner, C | 1 |
| Cano, E; Cohen, P; Cuenda, A; Hazzalin, CA; Mahadevan, LC | 1 |
| Fröhli, E; Kessler, R; Klemenz, R; Laursen, NB | 1 |
| Cao, X; Jain, N; Lim, CP | 1 |
| Jaakkola, P; Jalkanen, M; Kauppi, T; Kontusaari, S; Määtä, A | 1 |
| Camp, HS; Leff, T; Tafuri, SR | 1 |
| Cohen, P; Eyers, PA; Goedert, M; Quinlan, RA; van den IJssel, P | 1 |
| Gaestel, M; Kotlyarov, A; Neininger, A; Rolli, M; Sakamoto, KM | 1 |
| Fraser, CS; Morley, SJ; Pain, VM | 1 |
| McNicol, A; Pampolina, C | 1 |
| Szeberényi, J; Törocsik, B | 1 |
| Issinger, OG; Kim, SO; Pelech, SL; Salh, BS; Sayed, M | 1 |
| Gaestel, M; Rolli-Derkinderen, M | 1 |
| Cordis, GA; Das, DK; Maulik, N; Sato, M | 1 |
| Awad, MM; Boylan, JM; Davis, RJ; Enslen, H; Gruppuso, PA | 1 |
| Barth, P; Fillon, S; Gabrysch, S; Lang, F; Waldegger, S | 1 |
| Andersson, K; Sundler, R | 1 |
| Adachi, M; Imai, K; Itoh, F; Nakahata, A; Nakayama, I; Takekawa, M; Taya, Y; Tsukuda, H | 1 |
| Blanis, L; Hampong, M; Pelech, S; Shi, X; Zhang, H | 1 |
| Fennelly, C; Krause, D; Lyons, A; O'Connor, R | 1 |
| Bobrovskaya, L; Dunkley, PR; Leal, RB; Odell, A | 1 |
| Inaguma, Y; Ito, H; Iwamoto, I; Kato, K; Lida, K | 1 |
| Liu, AY; Park, J | 1 |
| Nihei, H; Nitta, K; Ohashi, T; Suzuki, H; Uchida, K; Yumura, W | 1 |
| Kucera, GL; Stadheim, TA | 1 |
| Kandolf, R; Küpper, JH; Meyer, RG; Rodemann, HP | 1 |
| Cohen, MV; Critz, SD; Downey, JM; Qin, Q; Yue, Y | 1 |
| Cohen, P; Haydon, CE; Knebel, A; Morrice, N | 1 |
| Junghae, M; Raynes, JG | 1 |
| Guan, KL; Inoki, K; Li, Y; Vacratsis, P | 1 |
| Akamatsu, S; Hatakeyama, D; Kozawa, O; Oiso, Y; Shibata, T; Tokuda, H | 1 |
| Kurland, JF; McDonnell, TJ; Meyn, RE; Munshi, A; Sah, NK; Su, B | 1 |
| Awasthi, A; Boppana, R; Jain, N; Joshi, BN; Khan, A; Mathur, R; Mitra, D; Saha, B; Sawant, S | 1 |
| Genade, S; Hattingh, S; Huisamen, B; Lochner, A; Marais, E; Moolman, JA | 1 |
| Brandt, E; Bulfone-Paus, S; Kasper, B; Petersen, F | 1 |
| Galiñanes, M; Hassouna, A; Loubani, M | 1 |
| Greene, SM; Headley, VV; Port, JD; Tanveer, R; Zweifach, A | 1 |
| Harada, A; Ishisaki, A; Kanno, Y; Kozawa, O; Takenaka, M; Tokuda, H | 1 |
| Hayashi, T; Kataoka, K; Kusunoki, Y; Kyoizumi, S; MacPhee, DG; Nakachi, K; Ogawa, T; Trosko, JE; Yorioka, N | 1 |
| Hanada, K; Kageyama, K; Suda, T | 1 |
| Dib-Hajj, SD; Hudmon, A; Rush, AM; Waxman, SG; Wittmack, EK | 1 |
| Arthur, JS; Beardmore, VA; Carr, JM; Hajduch, E; Hundal, HS; Sakamoto, K; Turban, S | 1 |
| Cherla, RP; Lee, SY; Mees, PL; Tesh, VL | 1 |
| Cao, X; Dawson, MI; Han, YH; Kolluri, SK; Lin, B; Lin, F; Reed, JC; Stebbins, J; Zhang, XK | 1 |
| Crisostomo, PR; Meldrum, DR; Morrell, ED; Tsai, BM; Wang, M | 1 |
| Hartley, S; Lochner, A; Marais, E; Moolman, JA; Van Wyk, J | 1 |
| Chen, J; Hai, T; Lu, D | 1 |
| Kuribayashi, F; Nakamura, M; Sakamoto, K; Takeshige, K | 1 |
| Asada, S; Daitoku, H; Fukamizu, A; Iwashita, S; Kako, K; Kasuya, Y; Kishi, T; Matsuzaki, H; Mukai, H; Saito, T; Sudo, T | 1 |
| Black, JA; Choi, JS; Dib-Hajj, SD; Hudmon, A; Rush, AM; Tyrrell, L; Waxman, SG | 1 |
| Cohick, WS; Leibowitz, BJ | 1 |
| Hata, Y; Ichisaka, S; Kaneko, R; Kato, K; Katoh-Semba, R; Kitajima, S; Miyazaki, N; Takahashi, Y; Tsuzuki, M; Yamada, H | 1 |
| Barone, FC; Dreixler, JC; Du, E; Roth, S; Shaikh, AR | 1 |
| Cui, YJ; Fukuda, S; Hirata, T; Ishida, K; Matsumoto, M; Mizukami, Y; Sakabe, T; Yamashita, S | 1 |
| Emery, AM; Ressurreição, M; Rollinson, D; Walker, AJ | 1 |
| Barhod, E; Hemi, R; Kanety, H; Karasik, A; Kasher-Meron, M; Tirosh, A; Yochananov, Y | 1 |
| Cao, W; Gu, H; Guo, H; He, K; Liu, Z; Mei, S; Ward, A; Yang, X | 1 |
| Pierucci-Alves, F; Schultz, BD; Yi, S | 1 |
| Barndt, RJ; Coticchia, CM; Deb, TB; Johnson, MD; Sengupta, S; Zuo, AH | 1 |
| Lei, X; Li, S; Li, Z; Lv, J; Meng, L; Xue, R; Zhang, Y; Zhang, Z | 1 |
| Huang, LJ; Ma, YC; Wang, WT; Wang, YY; Ying, L; Zheng, MX | 1 |
| Bian, Y; Ding, J; Hu, G; Lu, M; Shan, H; Shu, Z; Xiao, M; Zhang, L; Zhu, J | 1 |
| Do, SH; Fan, D; Han, SH; Ryu, JH; Wang, Z; Zuo, Z | 1 |
| Hou, R; Jia, S; Lei, DL; Wang, L; Wu, BL; Yang, XJ; Yang, ZH; Ye, C | 1 |
| Chang, M; Dou, G; Li, J; Liu, J; Liu, Z; Pei, X; Qin, J; Wang, S; Wang, Y; Yan, F; Zhang, B; Zhu, W | 1 |
| Concepcion, FA; D'Ambrosio, R; Fender, J; Jones, TD; Jung, S; Liu, Y; Neumaier, JF; Poolos, NP; Skyrud, DW; Tai, TY; Warner, LN; Williams, AD | 1 |
| Do, SH; Han, SH; Ryu, JH; Zuo, Z | 1 |
| Ewendt, F; Föller, M | 1 |
| Bai, C; Chai, L; Deng, P; Jia, Y; Li, J; Liu, C; Sun, Q; Zhao, X; Zheng, C | 1 |
72 other study(ies) available for sb 203580 and anisomycin
| Article | Year |
|---|---|
The activation of distinct mitogen-activated protein kinase cascades is required for the stimulation of 2-deoxyglucose uptake by interleukin-1 and insulin-like growth factor-1 in KB cells.
Topics: Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Deoxyglucose; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Insulin-Like Growth Factor I; Interleukin-1; KB Cells; Mitogen-Activated Protein Kinases; Monosaccharide Transport Proteins; p38 Mitogen-Activated Protein Kinases; Protein Synthesis Inhibitors; Pyridines; Signal Transduction; Stimulation, Chemical | 1995 |
p38/RK is essential for stress-induced nuclear responses: JNK/SAPKs and c-Jun/ATF-2 phosphorylation are insufficient.
Topics: Activating Transcription Factor 2; Animals; Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mice, Inbred C3H; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins c-jun; Pyridines; RNA, Messenger; Transcription Factors; Ultraviolet Rays | 1996 |
Differential regulation of the dual-specificity protein-tyrosine phosphatases CL100, B23, and PAC1 in mesangial cells.
Topics: Animals; Anisomycin; Cell Cycle Proteins; Cell Line; Dual Specificity Phosphatase 1; Dual Specificity Phosphatase 2; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Glomerular Mesangium; Humans; Imidazoles; Immediate-Early Proteins; Male; Nuclear Proteins; Nucleophosmin; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction | 1997 |
Phosphorylation of tyrosine 182 of p38 mitogen-activated protein kinase correlates with the protection of preconditioning in the rabbit heart.
Topics: Animals; Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Densitometry; Enzyme Activation; Enzyme Inhibitors; Heart; Hemodynamics; Imidazoles; Ischemic Preconditioning, Myocardial; Mitogen-Activated Protein Kinases; Models, Statistical; Myocardial Ischemia; Myocardium; Osmotic Pressure; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Synthesis Inhibitors; Pyridines; Rabbits; Tyrosine | 1997 |
Effects of the inhibition of p38/RK MAP kinase on induction of five fos and jun genes by diverse stimuli.
Topics: Animals; Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; Gene Expression Regulation; Genes, fos; Genes, jun; Imidazoles; Mice; Okadaic Acid; Pyridines; Transcriptional Activation; Tumor Necrosis Factor-alpha; Ultraviolet Rays | 1997 |
Effects of ras transformation on the induction of the IL-1 receptor related T1 gene in response to mitogens, anisomycin, IL-1 and TNFalpha.
Topics: 3T3 Cells; Animals; Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Cycloheximide; Enzyme Inhibitors; Gene Expression Regulation; Genes, ras; Imidazoles; Interleukin-1; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mitogens; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Pyridines; Receptors, Interleukin-1; Signal Transduction; Stimulation, Chemical; Transcriptional Activation; Transformation, Genetic; Tumor Necrosis Factor-alpha | 1998 |
Stress-induced immediate-early gene, egr-1, involves activation of p38/JNK1.
Topics: 3T3 Cells; Animals; Anisomycin; Arsenites; Calcium-Calmodulin-Dependent Protein Kinases; DNA; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Enzyme Inhibitors; ets-Domain Protein Elk-1; Gene Expression Regulation; Heat-Shock Response; Humans; Imidazoles; Immediate-Early Proteins; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Proto-Oncogene Proteins; Pyridines; RNA, Messenger; Sodium Compounds; Transcription Factors; Ultraviolet Rays | 1998 |
Wound reepithelialization activates a growth factor-responsive enhancer in migrating keratinocytes.
Topics: Animals; Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; Cell Movement; Enhancer Elements, Genetic; Enzyme Inhibitors; Epithelium; Fibroblast Growth Factors; Flavonoids; Gene Expression Regulation; Genistein; Imidazoles; In Vitro Techniques; Keratinocytes; Membrane Glycoproteins; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Proteoglycans; Pyridines; Receptors, Growth Factor; Skin Physiological Phenomena; Suramin; Syndecan-1; Syndecans; Transcriptional Activation; Wound Healing | 1998 |
c-Jun N-terminal kinase phosphorylates peroxisome proliferator-activated receptor-gamma1 and negatively regulates its transcriptional activity.
Topics: Animals; Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Inhibitors; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Transcription, Genetic; Ultraviolet Rays | 1999 |
Use of a drug-resistant mutant of stress-activated protein kinase 2a/p38 to validate the in vivo specificity of SB 203580.
Topics: Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Mutagenesis; p38 Mitogen-Activated Protein Kinases; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-raf; Pyridines; Ultraviolet Rays | 1999 |
Stress-induced stimulation of early growth response gene-1 by p38/stress-activated protein kinase 2 is mediated by a cAMP-responsive promoter element in a MAPKAP kinase 2-independent manner.
Topics: Activating Transcription Factor 1; Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP; Cyclic AMP Response Element Modulator; Cyclic AMP Response Element-Binding Protein; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Imidazoles; Immediate-Early Proteins; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Mitogen-Activated Protein Kinases; Mutation; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Pyridines; Regulatory Sequences, Nucleic Acid; Repressor Proteins; Ribosomal Protein S6 Kinases, 90-kDa; Transcription Factors | 1999 |
Cellular stress in xenopus kidney cells enhances the phosphorylation of eukaryotic translation initiation factor (eIF)4E and the association of eIF4F with poly(A)-binding protein.
Topics: Animals; Anisomycin; Arsenites; Cells, Cultured; Chromones; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Eukaryotic Initiation Factor-4F; Hot Temperature; Imidazoles; Kidney; Mitogen-Activated Protein Kinases; Morpholines; p38 Mitogen-Activated Protein Kinases; Peptide Initiation Factors; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Poly(A)-Binding Proteins; Protein Kinases; Pyridines; RNA-Binding Proteins; Sirolimus; TOR Serine-Threonine Kinases; Xenopus laevis | 1999 |
Anisomycin does not activate p38MAPK in human platelets.
Topics: Animals; Anisomycin; Blood Platelets; Collagen; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activation; Platelet Aggregation; Pyridines; Rabbits; Thrombin | 1999 |
Anisomycin uses multiple mechanisms to stimulate mitogen-activated protein kinases and gene expression and to inhibit neuronal differentiation in PC12 phaeochromocytoma cells.
Topics: Animals; Anisomycin; Cell Differentiation; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Imidazoles; Immediate-Early Proteins; JNK Mitogen-Activated Protein Kinases; Macromolecular Substances; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Models, Biological; Neoplasm Proteins; Nerve Growth Factor; Neurites; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyridines; ras Proteins; Rats; Reactive Oxygen Species; Receptor, Nerve Growth Factor; Receptor, trkA; Transcription Factors | 2000 |
Stress-induced activation of protein kinase CK2 by direct interaction with p38 mitogen-activated protein kinase.
Topics: Amino Acid Sequence; Anisomycin; Arsenites; Casein Kinase II; Enzyme Activation; Glutathione Transferase; HeLa Cells; Humans; Imidazoles; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; Recombinant Fusion Proteins; Tumor Necrosis Factor-alpha | 2000 |
p38/SAPK2-dependent gene expression in Jurkat T cells.
Topics: Anisomycin; Blotting, Northern; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Humans; Imidazoles; Jurkat Cells; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines; RNA, Messenger | 2000 |
SAPKs regulation of ischemic preconditioning.
Topics: Animals; Anisomycin; Curcumin; Enzyme Inhibitors; Heart; Imidazoles; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-jun; Pyridines; Rats; Rats, Sprague-Dawley | 2000 |
Growth regulation via p38 mitogen-activated protein kinase in developing liver.
Topics: Aging; Animals; Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Embryonic and Fetal Development; Enzyme Inhibitors; Fetus; Gestational Age; Hepatocytes; Imidazoles; Kinetics; Liver; MAP Kinase Kinase 6; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Transfection | 2000 |
h-sgk serine-threonine protein kinase as transcriptional target of p38/MAP kinase pathway in HepG2 human hepatoma cells.
Topics: Anisomycin; Cell Size; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Imidazoles; Immediate-Early Proteins; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nuclear Proteins; Osmotic Pressure; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; RNA, Messenger; Sodium Chloride; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Signalling to translational activation of tumour necrosis factor-alpha expression in human THP-1 cells.
Topics: Anisomycin; Blotting, Northern; Blotting, Western; Butadienes; Calcium; Cell Line; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Ionophores; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Monocytes; Nitriles; p38 Mitogen-Activated Protein Kinases; Protein Biosynthesis; Protein Synthesis Inhibitors; Pyridines; RNA, Messenger; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tumor Necrosis Factor-alpha | 2000 |
p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation.
Topics: Animals; Anisomycin; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Northern; Cell Nucleus; COS Cells; DNA Damage; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Gamma Rays; Glutathione Transferase; Humans; Hydrogen Peroxide; Imidazoles; Luciferases; Methyl Methanesulfonate; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Proteins; Plasmids; Precipitin Tests; Pyridines; Recombinant Fusion Proteins; Serine; Serine Proteinase Inhibitors; Signal Transduction; Threonine; Time Factors; Transfection; Tumor Suppressor Protein p53; Ultraviolet Rays | 2000 |
Stress-induced inhibition of ERK1 and ERK2 by direct interaction with p38 MAP kinase.
Topics: Animals; Anisomycin; Brain; Chromatography, Affinity; Cloning, Molecular; DNA, Complementary; Enzyme Activation; Glutathione Transferase; HeLa Cells; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Pyridines; Rats; Recombinant Fusion Proteins; Stress, Physiological | 2001 |
Transient activation of Jun N-terminal kinases and protection from apoptosis by the insulin-like growth factor I receptor can be suppressed by dicumarol.
Topics: Anisomycin; Apoptosis; Blotting, Western; Cell Line; Cell Survival; Cytoskeleton; Dicumarol; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Insulin Receptor Substrate Proteins; Interleukin-3; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Mutation; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Pyridines; Receptor, IGF Type 1; Recombinant Proteins; Time Factors; Transfection; Tumor Cells, Cultured; Tyrosine | 2001 |
Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of MAPKs after angiotensin II stimulation.
Topics: Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anisomycin; Antihypertensive Agents; Butadienes; Cattle; Chromaffin Cells; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Flavonoids; Imidazoles; Immunoblotting; Losartan; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Phosphoserine; Protein Synthesis Inhibitors; Pyridines; Receptors, Angiotensin; Time Factors; Tyrosine 3-Monooxygenase | 2001 |
Protein kinase inhibitors can suppress stress-induced dissociation of Hsp27.
Topics: Anisomycin; Arsenites; Butadienes; Cadmium Chloride; Carcinogens; Dithiothreitol; Enzyme Inhibitors; Flavonoids; Glioma; Heat-Shock Proteins; Humans; Hydrogen Peroxide; Imidazoles; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nitriles; Osmotic Pressure; Oxidants; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Synthesis Inhibitors; Pyridines; Sodium Compounds; Sorbitol; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
JNK phosphorylates the HSF1 transcriptional activation domain: role of JNK in the regulation of the heat shock response.
Topics: Animals; Anisomycin; Binding Sites; Cysteine Endopeptidases; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Heat Shock Transcription Factors; HeLa Cells; Hot Temperature; HSP70 Heat-Shock Proteins; Humans; Imidazoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Leupeptins; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Phosphorylation; Promoter Regions, Genetic; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Protein Structure, Tertiary; Pyridines; Rabbits; Recombinant Fusion Proteins; Signal Transduction; Stress, Physiological; Transcription Factors; Transcriptional Activation; Transfection | 2001 |
Involvement of MAP kinase cascades in Smad7 transcriptional regulation.
Topics: Animals; Anisomycin; Base Sequence; Cell Nucleus; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Flavonoids; Genes, Dominant; Imidazoles; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Molecular Sequence Data; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; Pyridines; Rats; RNA, Messenger; Smad7 Protein; Time Factors; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Transforming Growth Factor beta | 2001 |
c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for mitoxantrone- and anisomycin-induced apoptosis in HL-60 cells.
Topics: Anisomycin; Antineoplastic Agents; Apoptosis; Blotting, Western; DNA, Neoplasm; Flavonoids; HL-60 Cells; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Leukemia, Myeloid; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitoxantrone; p38 Mitogen-Activated Protein Kinases; Precipitin Tests; Protein Synthesis Inhibitors; Pyridines; Transfection | 2002 |
Early growth response-1 gene (Egr-1) promoter induction by ionizing radiation in U87 malignant glioma cells in vitro.
Topics: Androstadienes; Anisomycin; Blotting, Western; Colforsin; DNA-Binding Proteins; Early Growth Response Protein 1; Epidermal Growth Factor; Flavonoids; Glioma; Humans; Imidazoles; Immediate-Early Proteins; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Pyridines; Suramin; Transcription Factors; Wortmannin | 2002 |
The relative order of mK(ATP) channels, free radicals and p38 MAPK in preconditioning's protective pathway in rat heart.
Topics: Animals; Anisomycin; Decanoic Acids; Diazoxide; Enzyme Activators; Enzyme Inhibitors; Free Radical Scavengers; Free Radicals; Hydroxy Acids; Imidazoles; Ischemic Preconditioning, Myocardial; Male; Mitochondria, Heart; Mitogen-Activated Protein Kinases; Myocardial Infarction; p38 Mitogen-Activated Protein Kinases; Perfusion; Potassium Channel Blockers; Potassium Channels; Pyridines; Rats; Rats, Wistar; Signal Transduction; Tiopronin; Vitamin K 3 | 2002 |
Stress-induced regulation of eukaryotic elongation factor 2 kinase by SB 203580-sensitive and -insensitive pathways.
Topics: Amino Acid Sequence; Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Elongation Factor 2 Kinase; Enzyme Inhibitors; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinase 11; Mitogen-Activated Protein Kinase 13; Mitogen-Activated Protein Kinases; Molecular Sequence Data; p38 Mitogen-Activated Protein Kinases; Peptide Elongation Factor 2; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Serine; Signal Transduction; Stress, Physiological; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Activation of p38 mitogen-activated protein kinase attenuates Leishmania donovani infection in macrophages.
Topics: Animals; Anisomycin; Antiprotozoal Agents; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; In Vitro Techniques; Leishmania donovani; Leishmaniasis, Visceral; Lipopolysaccharides; Macrophages; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction | 2002 |
The p38 and MK2 kinase cascade phosphorylates tuberin, the tuberous sclerosis 2 gene product, and enhances its interaction with 14-3-3.
Topics: 14-3-3 Proteins; Amino Acid Sequence; Androstadienes; Anisomycin; Binding Sites; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Genes, Dominant; Glutathione Transferase; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Mass Spectrometry; Mitogen-Activated Protein Kinases; Models, Biological; Molecular Sequence Data; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; Recombinant Fusion Proteins; Repressor Proteins; Sequence Homology, Amino Acid; Serine; Time Factors; Tuberous Sclerosis; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins; Tyrosine 3-Monooxygenase; Wortmannin | 2003 |
p38 MAP kinase regulates BMP-4-stimulated VEGF synthesis via p70 S6 kinase in osteoblasts.
Topics: Animals; Anisomycin; Anti-Bacterial Agents; Blotting, Western; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Butadienes; Cell Line; Chromones; Endothelial Growth Factors; Enzyme-Linked Immunosorbent Assay; Flavonoids; Imidazoles; Intercellular Signaling Peptides and Proteins; Lymphokines; Mice; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Biosynthesis; Protein Synthesis Inhibitors; Proteins; Pyridines; Ribosomal Protein S6 Kinases, 70-kDa; Sirolimus; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase.
Topics: Activating Transcription Factor 2; Anisomycin; Apoptosis; Apoptosis Regulatory Proteins; Curcumin; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Genetic Vectors; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase Kinase 2; MAP Kinase Kinase Kinases; Membrane Glycoproteins; Mitogen-Activated Protein Kinases; Peptide Fragments; Prostatic Neoplasms; Protein Biosynthesis; Protein Synthesis Inhibitors; Pyridines; TNF-Related Apoptosis-Inducing Ligand; Transcription Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2003 |
CD40 signaling is impaired in L. major-infected macrophages and is rescued by a p38MAPK activator establishing a host-protective memory T cell response.
Topics: Animals; Anisomycin; CD40 Antigens; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Imidazoles; Leishmania major; Leishmaniasis, Cutaneous; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinases; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Protein Synthesis Inhibitors; Pyridines; Signal Transduction; Th1 Cells | 2003 |
Comparison between ischaemic and anisomycin-induced preconditioning: role of p38 MAPK.
Topics: Animals; Anisomycin; Anthracenes; Cardiac Output; Coronary Circulation; Disease Models, Animal; Enzyme Activation; Heart Rate; Imidazoles; Ischemic Preconditioning, Myocardial; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Myocardial Infarction; Myocardial Ischemia; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Wistar | 2003 |
Platelet factor 4 (PF-4)-induced neutrophil adhesion is controlled by src-kinases, whereas PF-4-mediated exocytosis requires the additional activation of p38 MAP kinase and phosphatidylinositol 3-kinase.
Topics: Anisomycin; Blotting, Western; Cell Adhesion; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Exocytosis; Humans; Imidazoles; Lactoferrin; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Platelet Factor 4; Precipitin Tests; Pyridines; Signal Transduction; src-Family Kinases; Time Factors | 2004 |
Delayed preconditioning of the human myocardium: signal transduction and clinical implications.
Topics: Acetylcholine; Aged; Alkaloids; Anisomycin; Antihypertensive Agents; Benzophenanthridines; Culture Techniques; Decanoic Acids; Diazoxide; Enzyme Activation; Enzyme Inhibitors; Female; Heart Atria; Humans; Hydroxy Acids; Imidazoles; Ischemic Preconditioning, Myocardial; Male; Middle Aged; Mitogen-Activated Protein Kinases; Myocardial Ischemia; Myocardium; p38 Mitogen-Activated Protein Kinases; Phenanthridines; Phenylephrine; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Pyridines; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors | 2004 |
Reciprocal regulation of beta-adrenergic receptor mRNA stability by mitogen activated protein kinase activation and inhibition.
Topics: 3' Untranslated Regions; Animals; Anisomycin; Anthracenes; Butadienes; Cell Line; Cricetinae; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Heterogeneous-Nuclear Ribonucleoproteins; Imidazoles; Mitogen-Activated Protein Kinase Kinases; Nitriles; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Pyridines; Receptors, Adrenergic, beta; RNA Stability; Signal Transduction | 2004 |
Interleukin (IL)-17 enhances tumor necrosis factor-alpha-stimulated IL-6 synthesis via p38 mitogen-activated protein kinase in osteoblasts.
Topics: Animals; Anisomycin; Cell Line; Dose-Response Relationship, Drug; Imidazoles; Interleukin-17; Interleukin-6; Lysophospholipids; Mice; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Sphingosine; Tumor Necrosis Factor-alpha | 2004 |
Anisomycin downregulates gap-junctional intercellular communication via the p38 MAP-kinase pathway.
Topics: Animals; Anisomycin; Blotting, Western; Connexin 43; Densitometry; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Fluorescence Recovery After Photobleaching; Fluorescent Antibody Technique, Indirect; Imidazoles; Immunoblotting; Immunohistochemistry; MAP Kinase Signaling System; Microscopy, Confocal; Microscopy, Fluorescence; p38 Mitogen-Activated Protein Kinases; Phosphates; Phosphorylation; Protein Synthesis Inhibitors; Pyridines; Rats; Rats, Inbred F344; Signal Transduction; Time Factors | 2004 |
Regulation of corticotropin-releasing factor receptor type 2beta mRNA by mitogen-activated protein kinases in aortic smooth muscle cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anisomycin; Aorta; Cell Line; Corticotropin-Releasing Hormone; Down-Regulation; Flavonoids; Gene Expression Regulation; Imidazoles; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Receptors, Corticotropin-Releasing Hormone; Ribonucleases; Up-Regulation; Urocortins | 2005 |
Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase.
Topics: Amino Acid Substitution; Animals; Anisomycin; Brain Chemistry; Cell Line; Enzyme Activation; Humans; Imidazoles; Ion Transport; Kidney; Male; Mice; Mutagenesis, Site-Directed; NAV1.6 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Neurons; p38 Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Phosphorylation; Phosphoserine; Protein Interaction Mapping; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Purkinje Cells; Pyridines; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Sodium; Sodium Channels; Tetrodotoxin; Transfection | 2005 |
Insulin-stimulated glucose uptake does not require p38 mitogen-activated protein kinase in adipose tissue or skeletal muscle.
Topics: Adipose Tissue; Animals; Anisomycin; Biological Transport; Blood Glucose; Body Weight; Gene Deletion; Glucose; Imidazoles; Insulin; Mice; Muscle, Skeletal; Myocardium; p38 Mitogen-Activated Protein Kinases; Pyridines; Signal Transduction | 2005 |
Shiga toxin 1-induced cytokine production is mediated by MAP kinase pathways and translation initiation factor eIF4E in the macrophage-like THP-1 cell line.
Topics: Aniline Compounds; Anisomycin; Anthracenes; Cell Line, Tumor; Cytokines; Dose-Response Relationship, Drug; Eukaryotic Initiation Factor-4E; Flavonoids; Humans; Imidazoles; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphorylation; Purines; Pyridines; RNA, Messenger; Shiga Toxin 1; Time Factors | 2006 |
Regulation of Nur77 nuclear export by c-Jun N-terminal kinase and Akt.
Topics: Adamantane; Anisomycin; Apoptosis; Cell Line, Tumor; Cell Nucleus; Cinnamates; DNA-Binding Proteins; Enzyme Activation; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 7; MAP Kinase Kinase Kinase 1; Mutagenesis, Site-Directed; Nuclear Receptor Subfamily 4, Group A, Member 1; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyridines; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Recombinant Fusion Proteins; Tetradecanoylphorbol Acetate; Transcription Factors | 2006 |
p38 mitogen-activated protein kinase mediates the sustained phase of hypoxic pulmonary vasoconstriction and plays a role in phase I vasodilation.
Topics: Animals; Anisomycin; Enzyme Activation; Enzyme Inhibitors; Hypoxia; Imidazoles; Isometric Contraction; Lung Diseases; Male; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Pulmonary Artery; Pyridines; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation | 2006 |
Inhibition of myocardial apoptosis by ischaemic and beta-adrenergic preconditioning is dependent on p38 MAPK.
Topics: Adrenergic beta-Agonists; Animals; Anisomycin; Apoptosis; Enzyme Activators; Imidazoles; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Isoproterenol; Models, Animal; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Necrosis; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines; Rats | 2006 |
The regulation of ATF3 gene expression by mitogen-activated protein kinases.
Topics: Activating Transcription Factor 3; Animals; Anisomycin; Chlorocebus aethiops; COS Cells; Enzyme Activation; Enzyme Induction; Flavonoids; Gene Expression Regulation; HeLa Cells; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 7; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines; Transcription Factors | 2007 |
Involvement of p38 MAP kinase in not only activation of the phagocyte NADPH oxidase induced by formyl-methionyl-leucyl-phenylalanine but also determination of the extent of the activity.
Topics: Anisomycin; Cytochalasin B; Enzyme Activation; Humans; Imidazoles; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Phagocytes; Pyridines; Superoxides | 2006 |
Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1.
Topics: Animals; Anisomycin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Inhibitors; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation, Enzymologic; Genes, Reporter; Humans; Imidazoles; Luciferases; Mice; NIH 3T3 Cells; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Synthesis Inhibitors; Pyridines | 2007 |
Phosphorylation of sodium channel Na(v)1.8 by p38 mitogen-activated protein kinase increases current density in dorsal root ganglion neurons.
Topics: Action Potentials; Animals; Anisomycin; Cells, Cultured; Electric Stimulation; Electroporation; Enzyme Activation; Ganglia, Spinal; Imidazoles; Immunoprecipitation; Male; Models, Biological; NAV1.8 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Neurons; p38 Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Phosphorylation; Protein Structure, Tertiary; Protein Synthesis Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Serine; Sodium Channels | 2008 |
Endogenous IGFBP-3 is required for both growth factor-stimulated cell proliferation and cytokine-induced apoptosis in mammary epithelial cells.
Topics: Animals; Anisomycin; Anthracenes; Apoptosis; Cattle; Cell Line; Cell Proliferation; DNA Replication; Enzyme Activation; Epithelial Cells; Female; Imidazoles; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; JNK Mitogen-Activated Protein Kinases; Mammary Glands, Animal; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines; RNA Interference; RNA, Messenger; RNA, Small Interfering; Time Factors; Tumor Necrosis Factor-alpha; Up-Regulation | 2009 |
Activation of p38 mitogen-activated protein kinase is required for in vivo brain-derived neurotrophic factor production in the rat hippocampus.
Topics: Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Anisomycin; Brain-Derived Neurotrophic Factor; Calcium Channel Blockers; Calcium Channels, N-Type; Enzyme Activation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hippocampus; Imidazoles; Male; Neurons; p38 Mitogen-Activated Protein Kinases; Protein Synthesis Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Riluzole; Up-Regulation | 2009 |
Mitogen-activated protein kinase p38alpha and retinal ischemic preconditioning.
Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Anisomycin; Diazoxide; Disease Models, Animal; Electroretinography; Enzyme Activators; Imidazoles; Intraocular Pressure; Ischemia; Ischemic Preconditioning; Mitogen-Activated Protein Kinase 14; Phosphorylation; Potassium Channels; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Reperfusion Injury; Retinal Neurons; Retinal Vessels; RNA Interference; Signal Transduction; Time Factors | 2009 |
Repeated preconditioning with hyperbaric oxygen induces neuroprotection against forebrain ischemia via suppression of p38 mitogen activated protein kinase.
Topics: Analysis of Variance; Animals; Anisomycin; Blotting, Western; Brain Ischemia; CA1 Region, Hippocampal; Cell Count; Cell Survival; Cytoprotection; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Hyperbaric Oxygenation; Imidazoles; Ischemic Preconditioning; Male; Memory, Short-Term; Neurons; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prosencephalon; Protein Synthesis Inhibitors; Pyridines; Rats; Rats, Wistar | 2009 |
A role for p38 MAPK in the regulation of ciliary motion in a eukaryote.
Topics: Amino Acid Sequence; Animals; Anisomycin; Cilia; Imidazoles; Larva; Molecular Sequence Data; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Schistosoma mansoni; Sequence Alignment | 2011 |
p38 mitogen-activated protein kinase-dependent transactivation of ErbB receptor family: a novel common mechanism for stress-induced IRS-1 serine phosphorylation and insulin resistance.
Topics: Animals; Anisomycin; Cell Line, Tumor; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Hep G2 Cells; Humans; Imidazoles; Immunoblotting; Immunoprecipitation; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, ErbB-3; Serine; Sphingomyelin Phosphodiesterase; Tumor Necrosis Factors | 2011 |
p38 mitogen-activated protein kinase (MAPK) promotes cholesterol ester accumulation in macrophages through inhibition of macroautophagy.
Topics: Anisomycin; Autophagy; Autophagy-Related Protein-1 Homolog; Cell Line; Cholesterol Esters; Enzyme Activation; Enzyme Activators; Gene Expression Regulation; Green Fluorescent Proteins; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Lipid Mobilization; Lipoproteins, LDL; Lysosomes; Macrophages; Microtubule-Associated Proteins; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; Recombinant Fusion Proteins | 2012 |
Transforming growth factor-β1 impairs CFTR-mediated anion secretion across cultured porcine vas deferens epithelial monolayer via the p38 MAPK pathway.
Topics: Animals; Anions; Anisomycin; Benzamides; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Dioxoles; Enzyme Inhibitors; Epithelial Cells; Imidazoles; Infertility, Male; Male; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Protein Synthesis Inhibitors; Pyridines; RNA, Messenger; Swine; Transforming Growth Factor beta1; Vas Deferens | 2013 |
PTEN-mediated ERK1/2 inhibition and paradoxical cellular proliferation following Pnck overexpression.
Topics: Anisomycin; Calcium-Calmodulin-Dependent Protein Kinase Type 1; Cell Line; Cell Proliferation; Enzyme Activation; Enzyme Activators; Epidermal Growth Factor; ErbB Receptors; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; PTEN Phosphohydrolase; Pyridines; ras Proteins | 2014 |
Baicalein reduces the invasion of glioma cells via reducing the activity of p38 signaling pathway.
Topics: Anisomycin; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Movement; Drug Synergism; Flavanones; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Microglia; p38 Mitogen-Activated Protein Kinases; Plant Extracts; Protein Kinase Inhibitors; Pyridines; Scutellaria baicalensis; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2 | 2014 |
[Expression of KATP in pulmonary artery smooth muscle cells under hypoxia-hypercapnia condition and the relationship with p38 MAPK pathway].
Topics: Animals; Anisomycin; Cell Hypoxia; Cells, Cultured; Hypercapnia; Imidazoles; KATP Channels; Male; MAP Kinase Signaling System; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Pulmonary Artery; Pyridines; Rats; Rats, Sprague-Dawley; Sulfonylurea Receptors | 2014 |
Fluoxetine protects against IL-1β-induced neuronal apoptosis via downregulation of p53.
Topics: Animals; Anisomycin; Apoptosis; bcl-2-Associated X Protein; Brain Ischemia; Cell Line, Tumor; Disease Models, Animal; Enzyme Inhibitors; Fluoxetine; Gene Expression; Imidazoles; Interleukin-1beta; MAP Kinase Signaling System; Mice, Inbred C57BL; Neuroimmunomodulation; Neurons; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Pyridines; Stroke; Tumor Suppressor Protein p53 | 2016 |
Isoflurane attenuates mouse microglial engulfment induced by lipopolysaccharide and interferon-γ possibly by inhibition of p38 mitogen-activated protein kinase.
Topics: Anesthetics; Animals; Animals, Newborn; Anisomycin; Calcium-Binding Proteins; Cells, Cultured; Cerebellum; Imidazoles; Interferon-gamma; Isoflurane; Lipopolysaccharides; Mice; Microfilament Proteins; Microglia; p38 Mitogen-Activated Protein Kinases; Protein Synthesis Inhibitors; Pyridines | 2016 |
Targeting P38 Pathway Regulates Bony Formation
Topics: Animals; Anisomycin; Bone Regeneration; Enzyme Inhibitors; Imidazoles; Male; Mandible; MAP Kinase Signaling System; Mesenchymal Stem Cells; Osteogenesis; Osteogenesis, Distraction; p38 Mitogen-Activated Protein Kinases; Pyridines; Random Allocation; Rats; Rats, Sprague-Dawley; X-Ray Microtomography | 2016 |
Connexin 32-mediated cell-cell communication is essential for hepatic differentiation from human embryonic stem cells.
Topics: Anisomycin; Biomarkers; Boron Compounds; Cell Communication; Cell Differentiation; Cell Line; Cell Lineage; Connexins; Cytochrome P-450 Enzyme System; Gap Junction beta-1 Protein; Gap Junctions; Gene Expression Regulation; Hepatocytes; Human Embryonic Stem Cells; Humans; Imidazoles; Liver; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Vitamin K 2 | 2016 |
Antiepileptic action of c-Jun N-terminal kinase (JNK) inhibition in an animal model of temporal lobe epilepsy.
Topics: Animals; Anisomycin; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Disease Models, Animal; Epilepsy, Temporal Lobe; Imidazoles; JNK Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Rats, Sprague-Dawley; Signal Transduction | 2017 |
Morphine reduces mouse microglial engulfment induced by lipopolysaccharide and interferon-γ via δ opioid receptor and p38 mitogen-activated protein kinase.
Topics: Analgesics, Opioid; Animals; Animals, Newborn; Anisomycin; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activators; Enzyme Inhibitors; Imidazoles; Interferon-gamma; Lipopolysaccharides; Mice; Microglia; Morphine; Naloxone; Narcotic Antagonists; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptors, Opioid, delta | 2018 |
p38MAPK controls fibroblast growth factor 23 (FGF23) synthesis in UMR106-osteoblast-like cells and in IDG-SW3 osteocytes.
Topics: Animals; Anisomycin; Cell Line; Enzyme Inhibitors; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Flavanones; Gene Expression Regulation; Imidazoles; Mice; NF-kappa B; Osteoblasts; Osteocytes; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Signal Transduction; Withanolides | 2019 |
Lipoxin A4-Mediated p38 MAPK Signaling Pathway Protects Mice Against Collagen-Induced Arthritis.
Topics: Animals; Anisomycin; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Proliferation; Collagen; Female; Imidazoles; Inflammation; Lipoxins; MAP Kinase Signaling System; Mice; Mice, Inbred DBA; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyridines; Signal Transduction; Synovial Membrane | 2021 |