Page last updated: 2024-09-05

sb 203580 and angiotensin ii

sb 203580 has been researched along with angiotensin ii in 42 studies

Compound Research Comparison

Studies (sb 203580)	Trials (sb 203580)	Recent Studies (post-2010) (sb 203580)	Studies (angiotensin ii)	Trials (angiotensin ii)	Recent Studies (post-2010) (angiotensin ii)
3,489	4	1,137	38,152	1,089	7,413

Protein Interaction Comparison

Protein	Taxonomy	angiotensin ii (IC50)
Atrial natriuretic peptide receptor 3	Homo sapiens (human)	0.002
Type-1A angiotensin II receptor	Rattus norvegicus (Norway rat)	0.002
Type-1B angiotensin II receptor	Rattus norvegicus (Norway rat)	0.0018
Type-1 angiotensin II receptor	Homo sapiens (human)	0.0055
Type-2 angiotensin II receptor	Rattus norvegicus (Norway rat)	0.004
Type-2 angiotensin II receptor	Homo sapiens (human)	0.0011

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (2.38)	18.2507
2000's	25 (59.52)	29.6817
2010's	16 (38.10)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H	1
Beck, FX; Burger-Kentischer, A; Fraek, ML; März, J; Müller, E; Neuhofer, W; Thurau, K	1
Aoki, H; Izumo, S; Richmond, M; Sadoshima, J	1
Giasson, E; Houle, F; Huot, J; Landry, J; Marceau, F; Meloche, S	1
McCulloch, CA; Seth, A; Wang, J	1
Fujii, S; Ichiki, T; Iino, N; Kitabatake, A; Shimokawa, H; Takeda, K; Takeshita, A; Tokunou, T	1
Bobrovskaya, L; Dunkley, PR; Leal, RB; Odell, A	1
Bevilaqua, LR; Cammarota, M; Dunkley, PR; Rostas, JA	1
Ertl, G; Jacobs, M; Scheuren, N; Schorb, W	1
Christoffersen, T; Hege Thoresen, G; Nilssen, LS; Sandnes, D	1
Funakoshi, Y; Ichiki, T; Iino, N; Takeda, K; Takeshita, A; Tokuno, T	1
Blaschke, F; Bruemmer, D; Kintscher, U; Law, RE; Unger, T	1
Griendling, KK; Rocic, P; Seshiah, P	1
Fujita, T; Goto, A; Hirata, Y; Nagai, R; Nishimatsu, H; Oba, S; Omata, M; Satonaka, H; Suzuki, E; Takeda, R	1
Cohen, RA; Hou, X; Jiang, B; Pimentel, DR; Xu, S	1
Ingelfinger, JR; Moini, B; Zhang, SL	1
Cha, DR; Han, DS; Han, KH; Han, SY; Jee, YH; Kang, SW; Kang, YS; Kim, BK; Lee, MH; Park, YG; Song, HK	1
Kawamoto, T; Kita, T; Nakashima, Y; Tanaka, M; Togi, K; Yamauchi, R; Yoshida, Y	1
Hasegawa, K; Hayashi, K; Homma, K; Itoh, H; Kimoto, M; Sugano, N; Tatematsu, S; Wakino, S; Yoshioka, K	1
Agrawal, DK; Cheng, G; Gangahar, DM; Jia, G; Mitra, AK	1
Bae, YM; Kim, B; Lee, CK; Lee, HM; Lee, KY; Lee, SH; Lee, YL; Lim, J; Park, PJ; Park, TK; Roh, HY; Won, KJ	1
Ahn, HY; Chae, YJ; Ha, TS; Hescheler, J; Kim, CH; Sachinidis, A	1
Eley, HL; Russell, ST; Tisdale, MJ	1
Akiyoshi, Y; Miyamoto, S; Morishima, M; Ono, K; Wang, Y	1
Carraro-Lacroix, LR; Girardi, AC; Malnic, G	1
Chan, JY; Chan, SH; Chang, AY; Ho, YH; Wu, CA; Wu, KL	1
Fang, Q; Li, HH; Liu, J; Tian, C; Yang, D; Zeng, Y; Zheng, YH	1
Caldwell, RB; Caldwell, RW; Carneiro, ZN; Chandra, S; Inscho, EW; Romero, MJ; Shatanawi, A; Toque, HA; Tostes, RC; Webb, RC	1
Al Ghouleh, I; Cascino, T; Csanyi, G; Haurani, MJ; Montezano, AC; Pagano, PJ; Touyz, RM	1
Han, C; Li, M; Liu, J; Mao, J; Pang, X; Wang, B	1
Andersen, DC; Christensen, GL; Eskildsen, T; Gammeltoft, S; Hansen, JL; Jensen, HB; Jeppesen, PL; Nossent, AY; Schneider, M; Sheikh, SP	1
Bruemmer, D; Daugherty, A; Golledge, J; Heywood, EB; Subramanian, V	1
Sun, HX; Yu, DJ; Yu, M; Zheng, Y	1
Ciccarelli, C; Desideri, G; Evangelista, S; Ferri, C; Festuccia, C; Grassi, D; Gravina, GL; Lovat, F; Marampon, F; Polidoro, L; Scarsella, L; Zani, BM	1
Ishikawa, M; Kanno, S; Nakagawasai, O; Nemoto, W; Tadano, T; Tan-No, K; Yaoita, F; Yomogida, S	1
Haack, KK; Mitra, AK; Zucker, IH	1
Feng, X; Gao, S; Liu, P; Liu, Z; Wang, J; Xu, S	1
Akamine, EH; Aragão, DS; Carvalho, MH; Casarini, DE; Filgueira, FP; Fortes, ZB; Hagihara, GN; Lobato, NS	1
Hao, J; Jiang, H; Meng, X; Saren, G; Wu, M; Yue, X; Zhang, Q; Zhang, X; Zhang, Y; Zhu, Q	1
Chi, C; Cui, L; Hou, F; Li, C; Liu, R; Liu, X; Wang, Y; Wen, Y; Yin, C; Yu, X	1
Jiang, X; Li, SH; Li, ZH; Liang, JX; Liao, X; Liu, HW; Wu, F; Wu, YD; Xu, Y; Yan, JX	1
Almeida-Pereira, G; Antunes-Rodrigues, J; Cognuck, SQ; Coletti, R; Elias, LLK; Silva, HVP; Vilhena-Franco, T	1

Other Studies

42 other study(ies) available for sb 203580 and angiotensin ii

Article	Year
Identifying off-target effects and hidden phenotypes of drugs in human cells. Nature chemical biology, 2006, Volume: 2, Issue:6 Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship	2006
Possible involvement of heat shock protein 25 in the angiotensin II-induced glomerular mesangial cell contraction via p38 MAP kinase. Journal of cellular physiology, 1999, Volume: 181, Issue:3 Topics: Angiotensin II; Animals; Cell Line; Enzyme Inhibitors; Glomerular Mesangium; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Imidazoles; Mice; Mitogen-Activated Protein Kinases; Molecular Chaperones; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; RNA, Messenger	1999
Specific role of the extracellular signal-regulated kinase pathway in angiotensin II-induced cardiac hypertrophy in vitro. The Biochemical journal, 2000, Apr-01, Volume: 347 Pt 1 Topics: Angiotensin II; Animals; Animals, Newborn; Cardiomegaly; Cells, Cultured; Enzyme Inhibitors; Heart; Heart Ventricles; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Cardiovascular; Myocardium; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; Recombinant Proteins; Signal Transduction; Transfection	2000
p38 MAP kinase pathway regulates angiotensin II-induced contraction of rat vascular smooth muscle. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:2 Topics: Angiotensin II; Animals; Aorta; Aorta, Thoracic; Calcium; Cells, Cultured; Egtazic Acid; Enzyme Inhibitors; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Imidazoles; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; Muscle Contraction; Muscle, Smooth, Vascular; Neoplasm Proteins; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Rats; Reactive Oxygen Species; Signal Transduction; Time Factors; Vasoconstriction	2000
Force regulates smooth muscle actin in cardiac fibroblasts. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:6 Topics: Actins; Angiotensin II; Animals; Antihypertensive Agents; Cells, Cultured; Colchicine; Enzyme Inhibitors; Fibroblasts; Gene Expression; Imidazoles; Losartan; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocardium; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Stress, Mechanical; Vasoconstrictor Agents	2000
Critical role of Rho-kinase and MEK/ERK pathways for angiotensin II-induced plasminogen activator inhibitor type-1 gene expression. Arteriosclerosis, thrombosis, and vascular biology, 2001, Volume: 21, Issue:5 Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Imidazoles; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Plasminogen Activator Inhibitor 1; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; RNA Processing, Post-Transcriptional; RNA, Messenger; Up-Regulation	2001
Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of MAPKs after angiotensin II stimulation. Journal of neurochemistry, 2001, Volume: 78, Issue:3 Topics: Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anisomycin; Antihypertensive Agents; Butadienes; Cattle; Chromaffin Cells; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Flavonoids; Imidazoles; Immunoblotting; Losartan; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Phosphoserine; Protein Synthesis Inhibitors; Pyridines; Receptors, Angiotensin; Time Factors; Tyrosine 3-Monooxygenase	2001
Angiotensin II promotes the phosphorylation of cyclic AMP-responsive element binding protein (CREB) at Ser133 through an ERK1/2-dependent mechanism. Journal of neurochemistry, 2001, Volume: 79, Issue:6 Topics: Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzylamines; Butadienes; Cattle; Cells, Cultured; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Enzyme Inhibitors; Imidazoles; Isoquinolines; Losartan; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Phosphoserine; Protein Processing, Post-Translational; Proto-Oncogene Proteins pp60(c-src); Pyridines; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Ribosomal Protein S6 Kinases; src-Family Kinases; Sulfonamides	2001
Cyclooxygenase-2 in myocardium stimulation by angiotensin-II in cultured cardiac fibroblasts and role at acute myocardial infarction. Journal of molecular and cellular cardiology, 2002, Volume: 34, Issue:1 Topics: Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Egg Proteins; Enzyme Inhibitors; Female; Fibroblasts; Flavonoids; Imidazoles; Immunoblotting; Immunoenzyme Techniques; Immunohistochemistry; Isoenzymes; Lactones; Macrophages; Membrane Glycoproteins; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Myocardium; Necrosis; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyridines; Rats; Rats, Wistar; Receptors, Cell Surface; Sulfones; Time Factors; Vimentin; Zona Pellucida Glycoproteins	2002
Differential role of MAP kinases in stimulation of hepatocyte growth by EGF and G-protein-coupled receptor agonists. Biochemical and biophysical research communications, 2002, Mar-01, Volume: 291, Issue:3 Topics: Angiotensin II; Animals; Cell Division; Dinoprost; DNA; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Hepatocytes; Heterotrimeric GTP-Binding Proteins; Imidazoles; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Norepinephrine; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Wistar; Receptors, Cell Surface; Vasopressins	2002
Critical role of cAMP-response element-binding protein for angiotensin II-induced hypertrophy of vascular smooth muscle cells. The Journal of biological chemistry, 2002, May-24, Volume: 277, Issue:21 Topics: Angiotensin II; Animals; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Flavonoids; Imidazoles; Muscle, Smooth, Vascular; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Transcription, Genetic	2002
p38 MAP kinase negatively regulates angiotensin II-mediated effects on cell cycle molecules in human coronary smooth muscle cells. Biochemical and biophysical research communications, 2003, Jun-06, Volume: 305, Issue:3 Topics: Angiotensin II; Cell Cycle; Cells, Cultured; Cyclin D1; DNA; Enzyme Inhibitors; Humans; Imidazoles; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocardium; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Retinoblastoma Protein; Thiazoles	2003
Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells. The Journal of biological chemistry, 2003, Sep-19, Volume: 278, Issue:38 Topics: Acetylcysteine; Angiotensin II; Animals; Aorta; Azoles; Blotting, Western; Carrier Proteins; Cells, Cultured; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Genes, Dominant; Imidazoles; Intracellular Signaling Peptides and Proteins; Isoindoles; Muscle, Smooth, Vascular; Okadaic Acid; Onium Compounds; Organoselenium Compounds; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Protein Phosphatase 2; Pyridines; Rats; Reactive Oxygen Species; Serine; Threonine; Time Factors	2003
Calcineurin promotes the expression of monocyte chemoattractant protein-1 in vascular myocytes and mediates vascular inflammation. Circulation research, 2004, Mar-19, Volume: 94, Issue:5 Topics: Angiotensin II; Animals; Calcineurin; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomyopathy, Hypertrophic; Cells, Cultured; Chemokine CCL2; Cyclosporine; Femoral Artery; Gene Expression Regulation; Humans; Hyperplasia; Imidazoles; Macrophages; MAP Kinase Kinase 6; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Promoter Regions, Genetic; Protein Biosynthesis; Proteins; Pyridines; Rats; Recombinant Fusion Proteins; RNA, Messenger; Signal Transduction; Tetrazoles; Transcription, Genetic; Tunica Intima; Valine; Valsartan; Vasculitis	2004
Angiotensin II differentially regulates interleukin-1-beta-inducible NO synthase (iNOS) and vascular cell adhesion molecule-1 (VCAM-1) expression: role of p38 MAPK. The Journal of biological chemistry, 2004, May-07, Volume: 279, Issue:19 Topics: Adenoviridae; Androstadienes; Angiotensin II; Animals; Blotting, Western; Cells, Cultured; Cyclooxygenase 2; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Imidazoles; Inflammation; Interleukin-1; Isoenzymes; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Models, Biological; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Time Factors; Vascular Cell Adhesion Molecule-1; Wortmannin	2004
Angiotensin II increases Pax-2 expression in fetal kidney cells via the AT2 receptor. Journal of the American Society of Nephrology : JASN, 2004, Volume: 15, Issue:6 Topics: Angiotensin II; Animals; Anthracenes; Blotting, Western; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Flavonoids; Genistein; Imidazoles; Kidney; Losartan; Mice; Microscopy, Fluorescence; Onium Compounds; PAX2 Transcription Factor; Phosphorylation; Plasmids; Pyridines; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Transcription Factors; Tyrphostins; Up-Regulation	2004
Angiotensin II stimulates the synthesis of vascular endothelial growth factor through the p38 mitogen activated protein kinase pathway in cultured mouse podocytes. Journal of molecular endocrinology, 2006, Volume: 36, Issue:2 Topics: Angiotensin II; Animals; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Electrophoretic Mobility Shift Assay; Enzyme Activation; Imidazoles; MAP Kinase Kinase 3; MAP Kinase Kinase 6; MAP Kinase Signaling System; Mice; p38 Mitogen-Activated Protein Kinases; Podocytes; Protein Kinase Inhibitors; Pyridines; Response Elements; RNA, Messenger; Transcriptional Activation; Up-Regulation; Vascular Endothelial Growth Factor A	2006
Endothelin-1 activates Homer 1alpha expression via mitogen-activated protein kinase in cardiac myocytes. International journal of molecular medicine, 2006, Volume: 18, Issue:1 Topics: Angiotensin II; Animals; Animals, Newborn; Blotting, Northern; Carrier Proteins; Cells, Cultured; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression; Homer Scaffolding Proteins; Imidazoles; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Protein Isoforms; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Time Factors	2006
Role of asymmetric dimethylarginine in vascular injury in transgenic mice overexpressing dimethylarginie dimethylaminohydrolase 2. Circulation research, 2007, Jul-20, Volume: 101, Issue:2 Topics: Amidohydrolases; Amlodipine; Angiotensin II; Animals; Arginine; Blood Pressure; Coronary Circulation; Coronary Vessels; Creatine Kinase, MB Form; Enzyme Activation; Enzyme Inhibitors; Fibrosis; Heart Diseases; Imidazoles; Mice; Mice, Transgenic; Myocardium; Nitric Oxide; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptidyl-Dipeptidase A; Pyridines; Time Factors; Tunica Media; Up-Regulation; Vasodilator Agents	2007
Angiotensin II and IGF-1 regulate connexin43 expression via ERK and p38 signaling pathways in vascular smooth muscle cells of coronary artery bypass conduits. The Journal of surgical research, 2007, Volume: 142, Issue:1 Topics: Aged; Angiotensin II; Cell Proliferation; Cells, Cultured; Connexin 43; Coronary Vessels; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Insulin-Like Growth Factor I; Male; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Pyridines; RNA, Messenger; Signal Transduction; Vasoconstrictor Agents	2007
p38 mitogen-activated protein kinase contributes to angiotensin II-stimulated migration of rat aortic smooth muscle cells. Journal of pharmacological sciences, 2007, Volume: 105, Issue:1 Topics: Actins; Angiotensin II; Animals; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Cell Movement; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Imidazoles; Intracellular Signaling Peptides and Proteins; Male; Mitogen-Activated Protein Kinase 1; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes; Syk Kinase; Vasoconstrictor Agents	2007
Epigallocatechin-3-O-gallate inhibits the angiotensin II-induced adhesion molecule expression in human umbilical vein endothelial cell via inhibition of MAPK pathways. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2007, Volume: 20, Issue:6 Topics: Angiotensin II; Catechin; Cell Membrane; Endothelial Cells; Enzyme Activation; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines; Umbilical Veins; Vascular Cell Adhesion Molecule-1	2007
Mechanism of attenuation of muscle protein degradation induced by tumor necrosis factor-alpha and angiotensin II by beta-hydroxy-beta-methylbutyrate. American journal of physiology. Endocrinology and metabolism, 2008, Volume: 295, Issue:6 Topics: Angiotensin II; Animals; Caspase 3; Caspase 8; Cells, Cultured; Down-Regulation; Drug Evaluation, Preclinical; Enzyme Inhibitors; Imidazoles; Interferon-gamma; Metabolic Networks and Pathways; Mice; Models, Biological; Muscle Fibers, Skeletal; Muscle Proteins; Muscular Atrophy; p38 Mitogen-Activated Protein Kinases; Phenylalanine; Protein Processing, Post-Translational; Pyridines; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Valerates	2008
Telmisartan, an angiotensin II type 1 receptor antagonist, attenuates T-type Ca2+ channel expression in neonatal rat cardiomyocytes. European journal of pharmacology, 2009, May-01, Volume: 609, Issue:1-3 Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Benzimidazoles; Benzoates; Calcium Channels, T-Type; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Extracellular Signal-Regulated MAP Kinases; F-Box Proteins; Flavonoids; Gene Expression Regulation; Heart Rate; Imidazoles; JNK Mitogen-Activated Protein Kinases; Membrane Potentials; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Patch-Clamp Techniques; Pyridines; Rats; Rats, Wistar; RNA, Messenger; Telmisartan; Tetrazoles; Time Factors; Valine; Valsartan; Zebrafish Proteins	2009
Long-term regulation of vacuolar H(+)-ATPase by angiotensin II in proximal tubule cells. Pflugers Archiv : European journal of physiology, 2009, Volume: 458, Issue:5 Topics: Ammonium Chloride; Androstadienes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Buffers; Cell Line, Transformed; Cell Membrane; Cycloheximide; Dactinomycin; Epithelial Cells; Gene Expression; Genistein; Hydrogen-Ion Concentration; Imidazoles; Kidney Tubules, Proximal; Losartan; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Protein Subunits; Protein Transport; Protein-Tyrosine Kinases; Pyridines; Rats; Time Factors; Up-Regulation; Vacuolar Proton-Translocating ATPases; Wortmannin	2009
Transcriptional upregulation of mitochondrial uncoupling protein 2 protects against oxidative stress-associated neurogenic hypertension. Circulation research, 2009, Oct-23, Volume: 105, Issue:9 Topics: Adenosine Triphosphate; Angiotensin II; Animals; Antioxidants; Blood Pressure; Blood Vessels; Catalase; Cell Respiration; Cyclic N-Oxides; Disease Models, Animal; Enzyme Inhibitors; Homeostasis; Humans; Hydrogen Peroxide; Hypertension; Imidazoles; Ion Channels; Male; Medulla Oblongata; Microinjections; Mitochondria; Mitochondrial Proteins; NADPH Oxidases; Onium Compounds; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation; PPAR gamma; Pyridines; Rats; Rats, Sprague-Dawley; RNA-Binding Proteins; Rosiglitazone; Spin Labels; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides; Sympathetic Nervous System; Thiazolidinediones; Time Factors; Transcription Factors; Transcriptional Activation; Transduction, Genetic; Uncoupling Protein 2; Up-Regulation	2009
Epigallocatechin gallate inhibits angiotensin II-induced endothelial barrier dysfunction via inhibition of the p38 MAPK/HSP27 pathway. Acta pharmacologica Sinica, 2010, Volume: 31, Issue:10 Topics: Angiotensin II; Catechin; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; HSP27 Heat-Shock Proteins; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; Stress Fibers; Umbilical Veins	2010
p38 Mitogen-activated protein kinase (MAPK) increases arginase activity and contributes to endothelial dysfunction in corpora cavernosa from angiotensin-II-treated mice. The journal of sexual medicine, 2010, Volume: 7, Issue:12 Topics: Angiotensin II; Animals; Arginase; Blood Pressure; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; Male; Mice; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Nitric Oxide Synthase; p38 Mitogen-Activated Protein Kinases; Penis; Phenylephrine; Phosphorylation; Pyridines; Vasoconstrictor Agents	2010
Adventitia-derived hydrogen peroxide impairs relaxation of the rat carotid artery via smooth muscle cell p38 mitogen-activated protein kinase. Antioxidants & redox signaling, 2011, Sep-15, Volume: 15, Issue:6 Topics: Angiotensin II; Animals; Carotid Arteries; Catalase; Connective Tissue; Disease Models, Animal; Hydrogen Peroxide; Imidazoles; Male; Muscle Relaxation; Myocytes, Smooth Muscle; Myography; p38 Mitogen-Activated Protein Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Pyridines; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vascular Diseases	2011
Angiotensin II induces the expression of c-reactive protein via MAPK-dependent signal pathway in U937 macrophages. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2011, Volume: 27, Issue:1 Topics: Acetylcysteine; Angiotensin II; Antihypertensive Agents; C-Reactive Protein; Flavonoids; Humans; Imidazoles; Losartan; Macrophages; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proline; Pyridines; Thiocarbamates; U937 Cells	2011
Angiotensin II type 1 receptor signalling regulates microRNA differentially in cardiac fibroblasts and myocytes. British journal of pharmacology, 2011, Volume: 164, Issue:2 Topics: Angiotensin II; Anthracenes; Butadienes; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Gene Expression Profiling; Gene Expression Regulation; GTP-Binding Protein alpha Subunits, Gq-G11; HEK293 Cells; Humans; Imidazoles; MicroRNAs; Myocytes, Cardiac; Nitriles; Pyridines; Receptor, Angiotensin, Type 1; Signal Transduction	2011
Regulation of peroxisome proliferator-activated receptor-γ by angiotensin II via transforming growth factor-β1-activated p38 mitogen-activated protein kinase in aortic smooth muscle cells. Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:2 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Cells, Cultured; Enzyme Inhibitors; Histone Deacetylases; Imidazoles; Losartan; Male; Mice; Mice, Inbred C57BL; Models, Animal; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; PPAR gamma; Pyridines; Receptor, Angiotensin, Type 1; RNA, Messenger; RNA, Small Interfering; Transforming Growth Factor beta1	2012
Inhibitory effects of enalaprilat on rat cardiac fibroblast proliferation via ROS/P38MAPK/TGF-β1 signaling pathway. Molecules (Basel, Switzerland), 2012, Mar-06, Volume: 17, Issue:3 Topics: Acetylcysteine; Active Transport, Cell Nucleus; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cell Proliferation; Cell Survival; Cells, Cultured; Enalaprilat; Fibroblasts; Gene Expression; Imidazoles; MAP Kinase Signaling System; Myocardium; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Plant Extracts; Pyridines; Rats; Rats, Inbred WKY; Reactive Oxygen Species; Transforming Growth Factor beta1	2012
Angiotensin-converting-enzyme inhibition counteracts angiotensin II-mediated endothelial cell dysfunction by modulating the p38/SirT1 axis. Journal of hypertension, 2013, Volume: 31, Issue:10 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Apoptosis; Captopril; Cell Nucleus; Cell Survival; Endothelial Cells; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; MAP Kinase Kinase 6; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyridines; Reactive Oxygen Species; Sirtuin 1; Superoxides	2013
Angiotensin II produces nociceptive behavior through spinal AT1 receptor-mediated p38 mitogen-activated protein kinase activation in mice. Molecular pain, 2013, Jul-31, Volume: 9 Topics: Angiotensin II; Animals; Imidazoles; Losartan; Male; MAP Kinase Signaling System; Mice; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptor, Angiotensin, Type 1; Spinal Cord	2013
NF-κB and CREB are required for angiotensin II type 1 receptor upregulation in neurons. PloS one, 2013, Volume: 8, Issue:11 Topics: Angiotensin II; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cyclic AMP Response Element-Binding Protein; ets-Domain Protein Elk-1; Humans; Imidazoles; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptor, Angiotensin, Type 1; Up-Regulation; Vasoconstrictor Agents	2013
Tumor suppressor gene ING3 induces cardiomyocyte hypertrophy via inhibition of AMPK and activation of p38 MAPK signaling. Archives of biochemistry and biophysics, 2014, Nov-15, Volume: 562 Topics: AMP-Activated Protein Kinases; Angiotensin II; Animals; Animals, Newborn; Aorta, Abdominal; Cardiomegaly; Cell Membrane; Imidazoles; Isoproterenol; Male; MAP Kinase Signaling System; Myocardium; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Phenylephrine; Plasmids; Pyridines; Rats; Rats, Sprague-Dawley; RNA Interference; Tumor Suppressor Proteins	2014
Upregulation of ERK1/2-eNOS via AT2 receptors decreases the contractile response to angiotensin II in resistance mesenteric arteries from obese rats. PloS one, 2014, Volume: 9, Issue:8 Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blotting, Western; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Male; Mesenteric Arteries; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Obesity; Phosphorylation; Pyridines; Rats, Wistar; Receptor, Angiotensin, Type 2; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents	2014
Angiotensin II upregulates endothelial lipase expression via the NF-kappa B and MAPK signaling pathways. PloS one, 2014, Volume: 9, Issue:9 Topics: Angiotensin II; Blotting, Western; Cell Proliferation; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Lipase; MAP Kinase Signaling System; Microscopy, Fluorescence; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrrolidines; Thiocarbamates; Time Factors; Transcription Factor RelA	2014
Angiotensin-converting enzyme 2-angiotensin (1-7)-Mas axis prevents pancreatic acinar cell inflammatory response via inhibition of the p38 mitogen-activated protein kinase/nuclear factor-κB pathway. International journal of molecular medicine, 2018, Volume: 41, Issue:1 Topics: Acinar Cells; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Humans; Imidazoles; Inflammation; Mice; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pancreas; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Receptors, G-Protein-Coupled; Signal Transduction	2018
A novel role of angiotensin II in epidermal cell lineage determination: Angiotensin II promotes the differentiation of mesenchymal stem cells into keratinocytes through the p38 MAPK, JNK and JAK2 signalling pathways. Experimental dermatology, 2019, Volume: 28, Issue:1 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Anthracenes; Bone Marrow Cells; Cell Differentiation; Cell Lineage; Cell Movement; Imidazoles; Janus Kinase 2; Janus Kinases; Keratinocytes; Losartan; Male; MAP Kinase Signaling System; Mesenchymal Stem Cells; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tyrphostins	2019
17β-Estradiol attenuates p38MAPK activity but not PKCα induced by angiotensin II in the brain. The Journal of endocrinology, 2019, 02-01, Volume: 240, Issue:2 Topics: Angiotensin II; Animals; Benzophenanthridines; Brain; Drinking; Drug Interactions; Estradiol; Female; Homeostasis; Imidazoles; MAP Kinase Signaling System; Ovariectomy; Oxytocin; p38 Mitogen-Activated Protein Kinases; Protein Kinase C-alpha; Pyridines; Rats, Wistar; Vasopressins	2019