Compounds > sb 203580
Page last updated: 2024-09-05

sb 203580 and alprostadil

sb 203580 has been researched along with alprostadil in 4 studies

Compound Research Comparison

Studies
(sb 203580)		Trials
(sb 203580)		Recent Studies (post-2010)
(sb 203580)		Studies
(alprostadil)		Trials
(alprostadil)		Recent Studies (post-2010) (alprostadil)
3,48941,1377,136864761

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)alprostadil (IC50)
Multidrug resistance-associated protein 4Homo sapiens (human)2.3
Solute carrier organic anion transporter family member 2B1Rattus norvegicus (Norway rat)0.0358

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Itoh, M; Kakita, A; Miura, Y; Oiso, Y; Ono, Y; Suzuki, A1
Ishisaki, A; Kanno, Y; Kozawa, O; Nakajima, K; Numata, O; Shibata, T; Tokuda, H1
Abramson, SB; Apsel, B; Chan, ES; Chang, LF; Clancy, R; Dinsell, V; Gomez, P; Marjanovic, N; Pillinger, MH; Tolani, SN1
Birnbaumer, L; Edwards, RA; Hoang, B; Trinh, A1

Other Studies

4 other study(ies) available for sb 203580 and alprostadil

ArticleYear
Possible involvement of p38 MAP kinase in prostaglandin E1-induced ALP activity in osteoblast-like cells.
    Prostaglandins, leukotrienes, and essential fatty acids, 2004, Volume: 70, Issue:5

    Topics: Adenylyl Cyclases; Alkaline Phosphatase; Alprostadil; Animals; Bucladesine; Cell Differentiation; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Imidazoles; Isoquinolines; Mice; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Sulfonamides

2004
Involvement of SAPK/JNK in prostaglandin E(1)-induced VEGF synthesis in osteoblast-like cells.
    Molecular and cellular endocrinology, 2004, May-31, Volume: 220, Issue:1-2

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alprostadil; Animals; Anthracenes; Cell Line; Colforsin; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-jun; Pyridines; Vascular Endothelial Growth Factor A

2004
Regulation of metalloproteinases and NF-kappaB activation in rabbit synovial fibroblasts via E prostaglandins and Erk: contrasting effects of nabumetone and 6MNA.
    British journal of pharmacology, 2004, Volume: 142, Issue:6

    Topics: Alprostadil; Analysis of Variance; Animals; Butadienes; Butanones; Cell Line; Cell Survival; Cyclooxygenase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Imidazoles; Interleukin-1; Matrix Metalloproteinase 1; Metalloendopeptidases; Nabumetone; Naphthaleneacetic Acids; NF-kappa B; Nitric Oxide; Nitriles; Phosphorylation; Prostaglandins E; Pyridines; Rabbits; Synovial Membrane; Tumor Necrosis Factor-alpha

2004
Decreased MAPK- and PGE2-dependent IL-11 production in Gialpha2-/- colonic myofibroblasts.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:6

    Topics: 16,16-Dimethylprostaglandin E2; Alprostadil; Animals; Cells, Cultured; Colon; Cyclic AMP; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; GTP-Binding Protein alpha Subunit, Gi2; Imidazoles; Interleukin-11; Interleukin-1beta; Intestine, Small; Methyl Ethers; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta

2007