sb 203580 has been researched along with afimoxifene in 5 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (afimoxifene) | Trials (afimoxifene) | Recent Studies (post-2010) (afimoxifene) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 1,255 | 10 | 325 |
| Protein | Taxonomy | sb 203580 (IC50) | afimoxifene (IC50) |
|---|---|---|---|
| Phospholipase D2 | Homo sapiens (human) | 6.5 | |
| Estrogen receptor | Homo sapiens (human) | 0.0105 | |
| Estrogen-related receptor gamma | Homo sapiens (human) | 0.0084 | |
| Phospholipase D1 | Homo sapiens (human) | 6.5 | |
| Estrogen receptor beta | Homo sapiens (human) | 0.0102 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shapiro, DJ; Zhang, CC | 1 |
| Bai, W; Jiang, F; Lee, H; Nicosia, SV; Su, B; Wang, Q; Yang, J | 1 |
| Balmanno, K; Cook, SJ; Garner, AP; Todd, DE; Weston, CR | 1 |
| Gutiérrez-Sagal, R; Herrera-Muñoz, J; Pasapera Limón, AM; Ulloa-Aguirre, A | 1 |
| Cheng, J; Shapiro, DJ; Yu, DV; Zhou, JH | 1 |
5 other study(ies) available for sb 203580 and afimoxifene
| Article | Year |
|---|---|
Activation of the p38 mitogen-activated protein kinase pathway by estrogen or by 4-hydroxytamoxifen is coupled to estrogen receptor-induced apoptosis.
Topics: Apoptosis; Breast Neoplasms; Cell Transformation, Neoplastic; Enzyme Induction; Estradiol; Female; HeLa Cells; Humans; Imidazoles; MAP Kinase Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein-Tyrosine Kinases; Pyridines; Receptors, Estrogen; Recombinant Proteins; Tamoxifen | 2000 |
MEKK1 activation of human estrogen receptor alpha and stimulation of the agonistic activity of 4-hydroxytamoxifen in endometrial and ovarian cancer cells.
Topics: Endometrial Neoplasms; Enzyme Activation; Enzyme Inhibitors; Estrogen Antagonists; Estrogen Receptor alpha; Female; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinase 2; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Pyridines; Receptors, Estrogen; Tamoxifen; Transcription, Genetic; Tumor Cells, Cultured | 2000 |
Delta MEKK3:ER* activation induces a p38 alpha/beta 2-dependent cell cycle arrest at the G2 checkpoint.
Topics: Animals; Aphidicolin; Apoptosis; CDC2 Protein Kinase; CDC2-CDC28 Kinases; Cells, Cultured; Cricetinae; Cyclin A; Cyclin B; Cyclin B1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; DNA Methylation; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; G1 Phase; G2 Phase; Gene Silencing; Genes, Synthetic; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 3; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase 11; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; Rats; Receptors, Estrogen; Recombinant Fusion Proteins; Sequence Deletion; Tamoxifen | 2002 |
The phosphatidylinositol 3-kinase inhibitor LY294002 binds the estrogen receptor and inhibits 17beta-estradiol-induced transcriptional activity of an estrogen sensitive reporter gene.
Topics: Animals; Binding Sites; Binding, Competitive; Cells, Cultured; Chromones; Enzyme Inhibitors; Estradiol; Female; Gene Expression Regulation; Genes, Reporter; Genetic Vectors; HeLa Cells; Humans; Imidazoles; Isoquinolines; L Cells; Mice; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Plasmids; Pyridines; Receptors, Estrogen; Sulfonamides; Tamoxifen; Transcription, Genetic | 2003 |
Delayed and persistent ERK1/2 activation is required for 4-hydroxytamoxifen-induced cell death.
Topics: Caspase 3; Caspase 9; Cell Death; Enzyme Activation; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Flavonoids; Fulvestrant; HeLa Cells; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptors, Estrogen; Tamoxifen; Time Factors | 2007 |