sb 203580 has been researched along with N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide in 3 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide) | Trials (N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide) | Recent Studies (post-2010) (N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 6 | 0 | 3 |
| Protein | Taxonomy | sb 203580 (IC50) | N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide (IC50) |
|---|---|---|---|
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | 1.5 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Angell, RM; Bamborough, P; Cleasby, A; Cockerill, SG; Jones, KL; Mooney, CJ; Somers, DO; Walker, AL | 1 |
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Astolfi, A; Barreca, ML; Brea, J; Cannalire, R; Cecchetti, F; Cecchetti, V; Fallarino, F; Felicetti, T; Kudolo, M; Laufer, SA; Loza, MI; Manfroni, G; Manni, G; Massari, S; Palazzotti, D; Sabatini, S; Tabarrini, O | 1 |
3 other study(ies) available for sb 203580 and N-(3-cyanophenyl)-2'-methyl-5'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxamide
| Article | Year |
|---|---|
Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode.
Topics: Amides; Biphenyl Compounds; Crystallography, X-Ray; Models, Molecular; Molecular Conformation; p38 Mitogen-Activated Protein Kinases; Protein Binding; Protein Kinase Inhibitors; Structure-Activity Relationship | 2008 |
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Discovery of potent p38α MAPK inhibitors through a funnel like workflow combining in silico screening and in vitro validation.
Topics: Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Healthy Volunteers; Humans; Mitogen-Activated Protein Kinase 14; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Structure-Activity Relationship | 2019 |