sb 203580 has been researched along with 7-n-butyl-6-(4'-hydroxyphenyl)-5h-pyrrolo(2,3b)pyrazine in 2 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (7-n-butyl-6-(4'-hydroxyphenyl)-5h-pyrrolo(2,3b)pyrazine) | Trials (7-n-butyl-6-(4'-hydroxyphenyl)-5h-pyrrolo(2,3b)pyrazine) | Recent Studies (post-2010) (7-n-butyl-6-(4'-hydroxyphenyl)-5h-pyrrolo(2,3b)pyrazine) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 9 | 0 | 3 |
| Protein | Taxonomy | sb 203580 (IC50) | 7-n-butyl-6-(4'-hydroxyphenyl)-5h-pyrrolo(2,3b)pyrazine (IC50) |
|---|---|---|---|
| Glycogen synthase kinase-3 beta | Sus scrofa (pig) | 0.65 | |
| [Tau protein] kinase | Sus scrofa (pig) | 0.65 | |
| G2/mitotic-specific cyclin-B2 | Homo sapiens (human) | 0.15 | |
| G1/S-specific cyclin-E2 | Homo sapiens (human) | 0.4 | |
| Cyclin-dependent kinase 1 | Saccharomyces cerevisiae S288C | 2.5 | |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | 0.15 | |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | 0.15 | |
| G2/mitotic-specific cyclin-B | Marthasterias glacialis (spiny starfish) | 0.3333 | |
| Glycogen synthase kinase-3 beta | Rattus norvegicus (Norway rat) | 0.3333 | |
| Cyclin-A2 | Homo sapiens (human) | 0.12 | |
| G1/S-specific cyclin-E1 | Homo sapiens (human) | 0.4 | |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | 0.26 | |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | 3.3 | |
| Mitogen-activated protein kinase 9 | Homo sapiens (human) | 3.3 | |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | 0.8239 | |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | 0.9326 | |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | 3.3 | |
| Cyclin-A1 | Homo sapiens (human) | 0.12 | |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | 0.245 | |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | 0.245 | |
| G2/mitotic-specific cyclin-B3 | Homo sapiens (human) | 0.15 | |
| Cyclin-dependent kinase 1 | Oryzias latipes (Japanese medaka) | 0.3333 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M | 1 |
| Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A | 1 |
2 other study(ies) available for sb 203580 and 7-n-butyl-6-(4'-hydroxyphenyl)-5h-pyrrolo(2,3b)pyrazine
| Article | Year |
|---|---|
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases | 2007 |
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase | 2013 |