Page last updated: 2024-09-05

sb 203580 and 7-hydroxystaurosporine

sb 203580 has been researched along with 7-hydroxystaurosporine in 2 studies

Compound Research Comparison

Studies (sb 203580)	Trials (sb 203580)	Recent Studies (post-2010) (sb 203580)	Studies (7-hydroxystaurosporine)	Trials (7-hydroxystaurosporine)	Recent Studies (post-2010) (7-hydroxystaurosporine)
3,489	4	1,137	322	20	51

Protein Interaction Comparison

Protein	Taxonomy	sb 203580 (IC50)	7-hydroxystaurosporine (IC50)
Serine/threonine-protein kinase Chk1	Homo sapiens (human)		0.0099
3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)		0.0055

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Castedo, M; Criollo, A; Galluzzi, L; Kroemer, G; Senovilla, L; Vitale, I; Vivet, S	1
Kayamori, T; Miyamoto, A; Murayama, C; Shimizu, T	1

Other Studies

2 other study(ies) available for sb 203580 and 7-hydroxystaurosporine

Article	Year
Chk1 inhibition activates p53 through p38 MAPK in tetraploid cancer cells. Cell cycle (Georgetown, Tex.), 2008, Jul-01, Volume: 7, Issue:13 Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Checkpoint Kinase 1; Down-Regulation; Enzyme Inhibitors; HCT116 Cells; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Polyploidy; Protein Kinase Inhibitors; Protein Kinases; Pyridines; RNA, Small Interfering; Staurosporine; Transfection; Tumor Suppressor Protein p53	2008
Bone morphogenetic protein (BMP)-4 and BMP-7 suppress granulosa cell apoptosis via different pathways: BMP-4 via PI3K/PDK-1/Akt and BMP-7 via PI3K/PDK-1/PKC. Biochemical and biophysical research communications, 2012, Jan-13, Volume: 417, Issue:2 Topics: Animals; Apoptosis; Bone Morphogenetic Protein 4; Bone Morphogenetic Protein 7; Cattle; Cells, Cultured; Chromones; Enzyme Inhibitors; Female; Granulosa Cells; Humans; Imidazoles; Morpholines; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyridines; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Staurosporine	2012

Article

Year

Chk1 inhibition activates p53 through p38 MAPK in tetraploid cancer cells.

Cell cycle (Georgetown, Tex.), 2008, Jul-01, Volume: 7, Issue:13

Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Checkpoint Kinase 1; Down-Regulation; Enzyme Inhibitors; HCT116 Cells; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Polyploidy; Protein Kinase Inhibitors; Protein Kinases; Pyridines; RNA, Small Interfering; Staurosporine; Transfection; Tumor Suppressor Protein p53

2008

Bone morphogenetic protein (BMP)-4 and BMP-7 suppress granulosa cell apoptosis via different pathways: BMP-4 via PI3K/PDK-1/Akt and BMP-7 via PI3K/PDK-1/PKC.

Biochemical and biophysical research communications, 2012, Jan-13, Volume: 417, Issue:2

Topics: Animals; Apoptosis; Bone Morphogenetic Protein 4; Bone Morphogenetic Protein 7; Cattle; Cells, Cultured; Chromones; Enzyme Inhibitors; Female; Granulosa Cells; Humans; Imidazoles; Morpholines; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Pyridines; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Staurosporine

2012