Page last updated: 2024-09-05

sb 203580 and 3,4-dihydro-2(1h)-quinolinone

sb 203580 has been researched along with 3,4-dihydro-2(1h)-quinolinone in 2 studies

Compound Research Comparison

Studies (sb 203580)	Trials (sb 203580)	Recent Studies (post-2010) (sb 203580)	Studies (3,4-dihydro-2(1h)-quinolinone)	Trials (3,4-dihydro-2(1h)-quinolinone)	Recent Studies (post-2010) (3,4-dihydro-2(1h)-quinolinone)
3,489	4	1,137	19	0	10

Protein Interaction Comparison

Protein	Taxonomy	3,4-dihydro-2(1h)-quinolinone (IC50)
Mitogen-activated protein kinase 13	Homo sapiens (human)	0.0007
Mitogen-activated protein kinase 12	Homo sapiens (human)	0.0007
Mitogen-activated protein kinase 11	Homo sapiens (human)	0.0007
Mitogen-activated protein kinase 14	Homo sapiens (human)	0.0007

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Domeyer, DM; Hauser, DR; Kammerer, B; Laufer, SA; Scior, T	1
Barlow, DJ; Ehrman, TM; Hylands, PJ	1

Other Studies

2 other study(ies) available for sb 203580 and 3,4-dihydro-2(1h)-quinolinone

Article	Year
Synthesis, biological testing, and binding mode prediction of 6,9-diarylpurin-8-ones as p38 MAP kinase inhibitors. Journal of medicinal chemistry, 2007, May-03, Volume: 50, Issue:9 Topics: Adenosine Triphosphate; Binding Sites; Drug Design; Hydrophobic and Hydrophilic Interactions; p38 Mitogen-Activated Protein Kinases; Protein Binding; Purinones; Structure-Activity Relationship; Thermodynamics	2007
In silico search for multi-target anti-inflammatories in Chinese herbs and formulas. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Anti-Inflammatory Agents; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Databases, Factual; Drug Design; Drugs, Chinese Herbal; Enzyme Inhibitors; JNK Mitogen-Activated Protein Kinases; Medicine, Chinese Traditional; Models, Chemical; Models, Molecular; Molecular Conformation; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase 4 Inhibitors; Structure-Activity Relationship	2010

Article

Year

Synthesis, biological testing, and binding mode prediction of 6,9-diarylpurin-8-ones as p38 MAP kinase inhibitors.

Journal of medicinal chemistry, 2007, May-03, Volume: 50, Issue:9

Topics: Adenosine Triphosphate; Binding Sites; Drug Design; Hydrophobic and Hydrophilic Interactions; p38 Mitogen-Activated Protein Kinases; Protein Binding; Purinones; Structure-Activity Relationship; Thermodynamics

2007

In silico search for multi-target anti-inflammatories in Chinese herbs and formulas.

Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

Topics: Anti-Inflammatory Agents; Crystallography, X-Ray; Cyclooxygenase 1; Cyclooxygenase 2; Databases, Factual; Drug Design; Drugs, Chinese Herbal; Enzyme Inhibitors; JNK Mitogen-Activated Protein Kinases; Medicine, Chinese Traditional; Models, Chemical; Models, Molecular; Molecular Conformation; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase 4 Inhibitors; Structure-Activity Relationship

2010