Compounds > sb 203580
Page last updated: 2024-09-05

sb 203580 and 3,3',4,5'-tetrahydroxystilbene

sb 203580 has been researched along with 3,3',4,5'-tetrahydroxystilbene in 8 studies

Compound Research Comparison

Studies
(sb 203580)		Trials
(sb 203580)		Recent Studies (post-2010)
(sb 203580)		Studies
(3,3',4,5'-tetrahydroxystilbene)		Trials
(3,3',4,5'-tetrahydroxystilbene)		Recent Studies (post-2010) (3,3',4,5'-tetrahydroxystilbene)
3,48941,137907
3,48941,1375472298

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)3,3',4,5'-tetrahydroxystilbene (IC50)
Tyrosine-protein kinase LckHomo sapiens (human)5
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)0.67
Tyrosine-protein kinase SYKHomo sapiens (human)10
Lactoylglutathione lyaseHomo sapiens (human)0.76
large T antigenBetapolyomavirus macacae16.35

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (87.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Barnes, PJ; Giembycz, MA; Lindsay, MA; Lynch, OT1
Benati, D; Berton, G; Gaino, S; Minuz, P; Ortolani, R; Santonastaso, CL; Tommasoli, RM; Zancanaro, C; Zuliani, V1
Figulla, HR; Foerster, M; Fritzenwanger, M; Krack, A; Kuethe, F; Meusel, K1
Choi, WS; Jeon, BH; Kim, B; Kim, HJ; Lee, CK; Lee, HM; Park, HJ; Park, TK; Roh, HY; Won, KJ1
Kim, B; Kim, HJ; Kim, J; Lee, CK; Lee, HM; Lee, SH; Park, HJ; Roh, HY; Won, KJ1
Bae, YM; Kim, B; Lee, CK; Lee, HM; Lee, KY; Lee, SH; Lee, YL; Lim, J; Park, PJ; Park, TK; Roh, HY; Won, KJ1

Other Studies

8 other study(ies) available for sb 203580 and 3,3',4,5'-tetrahydroxystilbene

ArticleYear
Navigating the kinome.
    Nature chemical biology, 2011, Volume: 7, Issue:4

    Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology

2011
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
Pharmacological comparison of LTB(4)-induced NADPH oxidase activation in adherent and non-adherent guinea-pig eosinophils.
    British journal of pharmacology, 2001, Volume: 134, Issue:4

    Topics: Androstadienes; Animals; Antibodies; Carbazoles; CD18 Antigens; Cell Adhesion; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Eosinophils; Flavonoids; Guinea Pigs; Imidazoles; Indoles; Integrin beta1; Intracellular Signaling Peptides and Proteins; Leukotriene B4; Macrophage-1 Antigen; Male; Maleimides; Mitogen-Activated Protein Kinases; NADPH Oxidases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Pyrimidines; Rats; src-Family Kinases; Stilbenes; Syk Kinase; Time Factors; Wortmannin

2001
Functional role of p38 mitogen activated protein kinase in platelet activation induced by a thromboxane A2 analogue and by 8-iso-prostaglandin F2alpha.
    Thrombosis and haemostasis, 2002, Volume: 87, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Actin Cytoskeleton; Actins; Adult; Antigens, CD; Blood Platelets; Cell Size; Cytochalasin D; Dinoprost; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; F2-Isoprostanes; Humans; Imidazoles; Integrin beta3; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Microscopy, Electron, Scanning; Mitogen-Activated Protein Kinases; P-Selectin; p38 Mitogen-Activated Protein Kinases; Platelet Activation; Platelet Adhesiveness; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Pseudopodia; Pyridines; Stilbenes; Syk Kinase; Thromboxane A2

2002
Cardiotrophin-1 induces interleukin-6 synthesis in human umbilical vein endothelial cells.
    Cytokine, 2006, Volume: 36, Issue:3-4

    Topics: Antibodies, Monoclonal; Cells, Cultured; Cycloheximide; Cytokines; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gene Expression; Humans; Imidazoles; Interleukin-6; Janus Kinase 2; Kinetics; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sesquiterpenes; STAT3 Transcription Factor; Stilbenes; Tyrphostins; Umbilical Cord

2006
Syk contributes to PDGF-BB-mediated migration of rat aortic smooth muscle cells via MAPK pathways.
    Cardiovascular research, 2007, Apr-01, Volume: 74, Issue:1

    Topics: Animals; Aorta; Becaplermin; Cell Movement; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Imidazoles; Immunoblotting; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Myocytes, Smooth Muscle; Phosphorylation; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-sis; Pyridines; Rats; Receptor, Platelet-Derived Growth Factor beta; RNA Interference; RNA, Small Interfering; Stilbenes; Syk Kinase; Transfection

2007
Endothelin-1 induces contraction via a Syk-mediated p38 mitogen-activated protein kinase pathway in rat aortic smooth muscle.
    Journal of pharmacological sciences, 2007, Volume: 103, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Enzyme Inhibitors; Flavonoids; Imidazoles; Immunoblotting; Immunoprecipitation; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Stilbenes; Syk Kinase; Vasoconstriction

2007
p38 mitogen-activated protein kinase contributes to angiotensin II-stimulated migration of rat aortic smooth muscle cells.
    Journal of pharmacological sciences, 2007, Volume: 105, Issue:1

    Topics: Actins; Angiotensin II; Animals; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; Cell Movement; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Imidazoles; Intracellular Signaling Peptides and Proteins; Male; Mitogen-Activated Protein Kinase 1; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Signal Transduction; Stilbenes; Syk Kinase; Vasoconstrictor Agents

2007