Page last updated: 2024-09-05

sb 203580 and 2-methoxyestradiol

sb 203580 has been researched along with 2-methoxyestradiol in 2 studies

Compound Research Comparison

Studies (sb 203580)	Trials (sb 203580)	Recent Studies (post-2010) (sb 203580)	Studies (2-methoxyestradiol)	Trials (2-methoxyestradiol)	Recent Studies (post-2010) (2-methoxyestradiol)
3,489	4	1,137	779	11	315

Protein Interaction Comparison

Protein	Taxonomy	2-methoxyestradiol (IC50)
Tubulin alpha-1A chain	Sus scrofa (pig)	2.2
Tubulin beta chain	Sus scrofa (pig)	2.2
Tubulin beta-2B chain	Bos taurus (cattle)	3.48
Similar to alpha-tubulin isoform 1	Bos taurus (cattle)	3.0667
Similar to alpha-tubulin isoform 1	Bos taurus (cattle)	3.9

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1
Adyshev, D; Bogatcheva, NV; Mambetsariev, B; Moldobaeva, N; Verin, AD	1

Other Studies

2 other study(ies) available for sb 203580 and 2-methoxyestradiol

Article	Year
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013
Involvement of microtubules, p38, and Rho kinases pathway in 2-methoxyestradiol-induced lung vascular barrier dysfunction. American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 292, Issue:2 Topics: 2-Methoxyestradiol; Actomyosin; Amides; Blood-Air Barrier; Cell Membrane Permeability; Endothelial Cells; Estradiol; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Microelectrodes; Microtubules; Models, Biological; Myosin-Light-Chain Kinase; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Protein Serine-Threonine Kinases; Pulmonary Artery; Pyridines; rho-Associated Kinases; Tubulin	2007

Article

Year

Identification of potent Yes1 kinase inhibitors using a library screening approach.

Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013

Involvement of microtubules, p38, and Rho kinases pathway in 2-methoxyestradiol-induced lung vascular barrier dysfunction.

American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 292, Issue:2

Topics: 2-Methoxyestradiol; Actomyosin; Amides; Blood-Air Barrier; Cell Membrane Permeability; Endothelial Cells; Estradiol; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Microelectrodes; Microtubules; Models, Biological; Myosin-Light-Chain Kinase; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Protein Serine-Threonine Kinases; Pulmonary Artery; Pyridines; rho-Associated Kinases; Tubulin

2007