sb 203580 has been researched along with 1-tert-butyl-3-naphthalen-1-ylmethyl-1h-pyrazolo(3,4-d)pyrimidin-4-ylemine in 2 studies
| Studies (sb 203580) | Trials (sb 203580) | Recent Studies (post-2010) (sb 203580) | Studies (1-tert-butyl-3-naphthalen-1-ylmethyl-1h-pyrazolo(3,4-d)pyrimidin-4-ylemine) | Trials (1-tert-butyl-3-naphthalen-1-ylmethyl-1h-pyrazolo(3,4-d)pyrimidin-4-ylemine) | Recent Studies (post-2010) (1-tert-butyl-3-naphthalen-1-ylmethyl-1h-pyrazolo(3,4-d)pyrimidin-4-ylemine) |
|---|---|---|---|---|---|
| 3,489 | 4 | 1,137 | 15 | 0 | 7 |
| Protein | Taxonomy | sb 203580 (IC50) | 1-tert-butyl-3-naphthalen-1-ylmethyl-1h-pyrazolo(3,4-d)pyrimidin-4-ylemine (IC50) |
|---|---|---|---|
| Receptor-interacting serine/threonine-protein kinase 2 | Homo sapiens (human) | 0.13 | |
| Serine/threonine-protein kinase D3 | Homo sapiens (human) | 0.616 | |
| Tyrosine-protein kinase ABL1 | Homo sapiens (human) | 1.76 | |
| Proto-oncogene tyrosine-protein kinase Src | Gallus gallus (chicken) | 0.62 | |
| Proto-oncogene tyrosine-protein kinase LCK | Mus musculus (house mouse) | 0.46 | |
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | 1 | |
| cAMP-dependent protein kinase catalytic subunit alpha | Homo sapiens (human) | 0.5 | |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | 0.005 | |
| Tyrosine-protein kinase CSK | Homo sapiens (human) | 0.51 | |
| Mitogen-activated protein kinase 8 | Homo sapiens (human) | 0.195 | |
| Serine/threonine-protein kinase D1 | Homo sapiens (human) | 0.6315 | |
| Serine/threonine-protein kinase D2 | Homo sapiens (human) | 0.786 | |
| Cyclin-dependent kinase 12 | Homo sapiens (human) | 0.1 | |
| Calcium/calmodulin-dependent protein kinase type II subunit alpha | Homo sapiens (human) | 0.008 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N | 1 |
| Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A | 1 |
2 other study(ies) available for sb 203580 and 1-tert-butyl-3-naphthalen-1-ylmethyl-1h-pyrazolo(3,4-d)pyrimidin-4-ylemine
| Article | Year |
|---|---|
The selectivity of protein kinase inhibitors: a further update.
Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera | 2007 |
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase | 2013 |