Compounds > sb 203580
Page last updated: 2024-09-05

sb 203580 and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine

sb 203580 has been researched along with 1-hexadecyl-2-acetyl-glycero-3-phosphocholine in 12 studies

Compound Research Comparison

Studies
(sb 203580)		Trials
(sb 203580)		Recent Studies (post-2010)
(sb 203580)		Studies
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)		Trials
(1-hexadecyl-2-acetyl-glycero-3-phosphocholine)		Recent Studies (post-2010) (1-hexadecyl-2-acetyl-glycero-3-phosphocholine)
3,48941,1379,156187552

Protein Interaction Comparison

ProteinTaxonomysb 203580 (IC50)1-hexadecyl-2-acetyl-glycero-3-phosphocholine (IC50)
Platelet-activating factor receptorHomo sapiens (human)0.0003

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's7 (58.33)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hajjar, JJ; Molski, TF; Nagarkatti, D; Sha'afi, RI; Syrbu, SI; Waterman, WH1
Gon, Y; Hashimoto, S; Hayashi, S; Horie, T; Kujime, K; Maruoka, S; Matsumoto, K; Takeshita, I1
Dun, Y; Sun, HY; Zhao, RR; Zhao, ZQ; Zhi, JM1
Huang, XL; Lawrence, M; Madara, P; Nanavaty, UB; Pawliczak, R; Shelhamer, JH1
Biffl, WL; Carnaggio, R; Ciesla, DJ; Johnson, JL; Moore, EE; Silliman, CC1
Bissonnette, SA; Brown, GE; Elia, AE; Stewart, MQ; Wilker, E; Yaffe, MB1
Baker, PR; O'Flaherty, JT; Owen, JS; Samuel, MP; Thomas, MJ; Wooten, RE; Wykle, RL1
Aomatsu, K; Arakawa, T; Fujita, H; Hato, F; Kamata, N; Kato, T; Kitagawa, S; Oshitani, N; Tamura, T1
Behar, J; Biancani, P; Cao, W; Harnett, KM; Ma, J1
Abdel-Al, M; Ditmyer, M; Howard, KM; Patel, N1
Cong, Q; Jiang, W; Li, MJ; Wang, YS; Xu, CJ; Ye, B1
Andrews, MA; Austin, M; Ibe, BO; Lazaro, M; Lustina, J; Raj, JU; Renteria, LS1

Other Studies

12 other study(ies) available for sb 203580 and 1-hexadecyl-2-acetyl-glycero-3-phosphocholine

ArticleYear
Phosphorylation of cytosolic phospholipase A2 and the release of arachidonic acid in human neutrophils.
    Journal of immunology (Baltimore, Md. : 1950), 1999, Feb-15, Volume: 162, Issue:4

    Topics: Acyltransferases; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Cytosol; Flavonoids; Humans; Imidazoles; Lipopolysaccharides; Microsomes; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Activating Factor; Protein Kinase C; Pyridines; Tumor Necrosis Factor-alpha; Tyrosine

1999
p38 MAP kinase regulates TNF alpha-, IL-1 alpha- and PAF-induced RANTES and GM-CSF production by human bronchial epithelial cells.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2000, Volume: 30, Issue:1

    Topics: Animals; Bronchi; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Transformed; Chemokine CCL5; Enzyme Inhibitors; Epithelial Cells; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; Interleukin-1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Pyridines; Rabbits; Tumor Necrosis Factor-alpha

2000
Activated polymorphonuclear leukocytes induce cardiomyocyte apoptosis and the protective effects of carvedilol.
    Methods and findings in experimental and clinical pharmacology, 2002, Volume: 24, Issue:7

    Topics: Animals; Animals, Newborn; Antioxidants; Apoptosis; Carbazoles; Carvedilol; Cells, Cultured; DNA Fragmentation; Enzyme Inhibitors; Flow Cytometry; Imidazoles; In Situ Nick-End Labeling; Microscopy, Electron; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Neutrophils; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Propanolamines; Pyridines; Rats; Signal Transduction

2002
Oxidative stress induces arachidonate release from human lung cells through the epithelial growth factor receptor pathway.
    American journal of respiratory cell and molecular biology, 2002, Volume: 27, Issue:6

    Topics: Antineoplastic Agents; Arachidonic Acid; Calcium; Cells, Cultured; Cytosol; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Humans; Hydrogen Peroxide; Imidazoles; Ionophores; Lung; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Oxidants; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phosphorylation; Platelet Activating Factor; Protein Serine-Threonine Kinases; Pyridines; Quinazolines; ras Proteins; RNA, Messenger; Tumor Necrosis Factor-alpha; Tyrosine; Tyrphostins

2002
Clinically relevant hypertonicity prevents stored blood- and lipid-mediated delayed neutrophil apoptosis independent of p38 MAPK or caspase-3 activation.
    Surgery, 2003, Volume: 134, Issue:1

    Topics: Apoptosis; Blood Preservation; Caspase 3; Caspase Inhibitors; Caspases; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; In Vitro Techniques; Lysophosphatidylcholines; Mitogen-Activated Protein Kinases; Multiple Organ Failure; Neutrophils; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Pyridines; Saline Solution, Hypertonic

2003
Distinct ligand-dependent roles for p38 MAPK in priming and activation of the neutrophil NADPH oxidase.
    The Journal of biological chemistry, 2004, Jun-25, Volume: 279, Issue:26

    Topics: Animals; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; Ligands; Luminescent Measurements; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; NADPH Oxidases; Neutrophil Activation; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Platelet Activating Factor; Pyridines; Reactive Oxygen Species; Swine; Tumor Necrosis Factor-alpha; Zymosan

2004
Stress-induced platelet-activating factor synthesis in human neutrophils.
    Biochimica et biophysica acta, 2005, Apr-15, Volume: 1733, Issue:2-3

    Topics: Acetyltransferases; Chromatography, Liquid; Dimethyl Sulfoxide; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Imidazoles; Mass Spectrometry; Neutrophils; Osmotic Pressure; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Pyridines

2005
Toll-like receptor agonists stimulate human neutrophil migration via activation of mitogen-activated protein kinases.
    Immunology, 2008, Volume: 123, Issue:2

    Topics: Butadienes; Chemotaxis, Leukocyte; Dose-Response Relationship, Immunologic; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; Imidazoles; Lipopolysaccharides; Lipoproteins; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Pyridines; Toll-Like Receptors

2008
Signaling in TRPV1-induced platelet activating factor (PAF) in human esophageal epithelial cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:2

    Topics: Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Capsaicin; Cells, Cultured; Enzyme Inhibitors; Epithelial Cells; Esophagus; Humans; Imidazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Sensory System Agents; Signal Transduction; TRPV Cation Channels

2010
Lipopolysaccharide and platelet-activating factor stimulate expression of platelet-activating factor acetylhydrolase via distinct signaling pathways.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2011, Volume: 60, Issue:8

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Azepines; Cell Line; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Imidazoles; Lipopolysaccharides; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, G-Protein-Coupled; RNA, Messenger; Triazoles

2011
[Effects and mechanisms of platelet-activating factor on the invasiveness of ovarian cancer cells in vitro].
    Zhonghua fu chan ke za zhi, 2011, Volume: 46, Issue:12

    Topics: Blood Platelets; Blotting, Western; Carcinoma, Ovarian Epithelial; Cell Migration Assays; Cyclic AMP Response Element-Binding Protein; Female; Humans; Imidazoles; In Vitro Techniques; Matrix Metalloproteinase 2; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, G-Protein-Coupled; Time Factors

2011
RhoA-Rho kinase and platelet-activating factor stimulation of ovine foetal pulmonary vascular smooth muscle cell proliferation.
    Cell proliferation, 2013, Volume: 46, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Cell Hypoxia; Cell Proliferation; Cells, Cultured; Flavonoids; Imidazoles; Lung; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth, Vascular; Mutation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pyridines; Receptors, G-Protein-Coupled; rho-Associated Kinases; rhoA GTP-Binding Protein; Sheep

2013