satavaptan has been researched along with relcovaptan in 19 studies
| Studies (satavaptan) | Trials (satavaptan) | Recent Studies (post-2010) (satavaptan) | Studies (relcovaptan) | Trials (relcovaptan) | Recent Studies (post-2010) (relcovaptan) |
|---|---|---|---|---|---|
| 95 | 11 | 30 | 120 | 9 | 40 |
| Protein | Taxonomy | satavaptan (IC50) | relcovaptan (IC50) |
|---|---|---|---|
| Vasopressin V1a receptor | Homo sapiens (human) | 0.013 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (31.58) | 18.2507 |
| 2000's | 9 (47.37) | 29.6817 |
| 2010's | 4 (21.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishii, N; Kusayama, T; Saito, M; Sugimoto, T; Tahara, A; Tanaka, A; Tomura, Y; Tsukada, J; Uchida, W; Wada, K; Yatsu, T | 1 |
| Akerlund, M; Bossmar, T; Brouard, R; Kostrzewska, A; Laudanski, T; Lemancewicz, A; Serradeil-Le Gal, C; Steinwall, M | 1 |
| Aumelas, A; Balestre, MN; Barberis, C; Cotte, N; Durroux, T; Hibert, M; Mahé, E; Manning, M; Morin, D; Mouillac, B; Phalipou, S | 1 |
| Double-Cazanave, E; Garcia, C; Guillon, G; Maffrand, JP; Pascal, M; Raufaste, D; Serradeil-Le Gal, C | 1 |
| Ishii, N; Kusayama, T; Tahara, A; Tanaka, A; Taniguchi, N; Tomura, Y; Tsukada, J; Uchida, W; Yatsu, T | 1 |
| Arnaudguilhem, C; Bouyssiere, B; Cantel, S; Cheignon, C; Cordeau, E; Enjalbal, C; Martinez, J; Prache, N; Subra, G | 1 |
| Ishii, N; Kusayama, T; Saito, M; Tahara, A; Tanaka, A; Tomura, Y; Tsukada, J; Uchida, W; Wada, K; Yatsu, T | 1 |
| Dayanithi, G; Gouzénes, L; Moos, FC; Richard, P; Sabatier, N | 1 |
| Dayanithi, G; Gouzènes, L; Moos, FC | 1 |
| Cros, G; Laurent, F; Méchaly, I; Portet, K; Serrano, J | 1 |
| Chevaleyre, V; Dayanithi, G; Desarmenien, MG; Moos, FC | 1 |
| Abe, K; Furuichi, K; Saito, M; Sugimoto, T; Tahara, A | 1 |
| Chevaleyre, V; Desarménien, MG; Moos, FC | 1 |
| Deen, PM; Knoers, NV; Robben, JH; Sze, M | 1 |
| Abassi, ZA; Abu-Saleh, N; Azzam, ZS; Bishara, B; Hoffman, A; Karram, T; Nitecki, S; Rubinstein, I; Shiekh, H; Winaver, J | 1 |
| Haass, M | 1 |
| Abassi, Z; Azzam, ZS; Berger, G; Bishara, B; Guetta, J; Ismael-Badarneh, R; Klorin, G; Sabo, E; Tal, R | 1 |
| Krieg, SM; Plesnila, N; Sonanini, S; Trabold, R | 1 |
| Erdem Tuncdemir, B; Mergen, H; Saglar Ozer, E | 1 |
1 review(s) available for satavaptan and relcovaptan
| Article | Year |
|---|---|
[Vasopressin receptor antagonists and heart failure].
Topics: Administration, Oral; Aged; Antidiuretic Hormone Receptor Antagonists; Azepines; Benzamides; Benzazepines; Controlled Clinical Trials as Topic; Female; Follow-Up Studies; Furosemide; Heart Failure; Hormone Antagonists; Humans; Hyponatremia; Indoles; Male; Morpholines; Platelet Aggregation Inhibitors; Pyrroles; Pyrrolidines; Sodium Potassium Chloride Symporter Inhibitors; Spiro Compounds; Time Factors; Tolvaptan | 2009 |
18 other study(ies) available for satavaptan and relcovaptan
| Article | Year |
|---|---|
Pharmacological characterization of the human vasopressin receptor subtypes stably expressed in Chinese hamster ovary cells.
Topics: Animals; Benzazepines; Binding, Competitive; Calcium; CHO Cells; Cricetinae; Cyclic AMP; Humans; Indoles; Morpholines; Piperidines; Pyrrolidines; Quinolones; Receptors, Vasopressin; Spiro Compounds; Transfection; Tritium | 1998 |
Receptor binding of oxytocin and vasopressin antagonists and inhibitory effects on isolated myometrium from preterm and term pregnant women.
Topics: Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Cell Line; Cesarean Section; Female; Hormone Antagonists; Humans; Indoles; Morpholines; Myometrium; Obstetric Labor, Premature; Oxytocin; Pregnancy; Pyrrolidines; Receptors, Oxytocin; Spiro Compounds; Vasopressins | 1999 |
Conserved aromatic residues in the transmembrane region VI of the V1a vasopressin receptor differentiate agonist vs. antagonist ligand binding.
Topics: Amino Acid Sequence; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Binding Sites; Cell Membrane; Conserved Sequence; COS Cells; Humans; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Receptors, Vasopressin | 2000 |
Binding properties of a selective tritiated vasopressin V2 receptor antagonist, [H]-SR 121463.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Binding, Competitive; Cattle; CHO Cells; Cricetinae; Dogs; Haplorhini; Homeostasis; Humans; Kidney; Kinetics; Morpholines; Rabbits; Radioligand Assay; Rats; Spiro Compounds; Swine; Tritium; Vasopressins; Water-Electrolyte Balance | 2000 |
Effects of YM471, a nonpeptide AVP V(1A) and V(2) receptor antagonist, on human AVP receptor subtypes expressed in CHO cells and oxytocin receptors in human uterine smooth muscle cells.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Azepines; Binding, Competitive; Calcium; Cell Membrane; CHO Cells; Cricetinae; Cyclic AMP; Dose-Response Relationship, Drug; Female; Humans; Indoles; Morpholines; Muscle, Smooth; Oxytocin; Piperidines; Pyrrolidines; Radioligand Assay; Receptors, Oxytocin; Receptors, Vasopressin; Spiro Compounds; Tritium; Uterus | 2001 |
Receptor-Ligand Interaction Measured by Inductively Coupled Plasma Mass Spectrometry and Selenium Labeling.
Topics: Animals; CHO Cells; Cricetulus; Isotope Labeling; Ligands; Mass Spectrometry; Peptides; Protein Binding; Receptor, Cholecystokinin B; Selenium; Vasopressins | 2018 |
Vasopressin increases vascular endothelial growth factor secretion from human vascular smooth muscle cells.
Topics: Antidiuretic Hormone Receptor Antagonists; Benzazepines; Cell Line; Dose-Response Relationship, Drug; Endothelial Growth Factors; Humans; Indoles; Lymphokines; Morpholines; Muscle, Smooth, Vascular; Pyrrolidines; Spiro Compounds; Time Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasoconstrictor Agents; Vasopressins | 1999 |
V1a- and V2-type vasopressin receptors mediate vasopressin-induced Ca2+ responses in isolated rat supraoptic neurones.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Calcium; Deamino Arginine Vasopressin; In Vitro Techniques; Indoles; Kinetics; Male; Morpholines; Neurons; Pyrrolidines; Rats; Rats, Wistar; Receptors, Vasopressin; Spiro Compounds; Supraoptic Nucleus; Transcription, Genetic; Vasoconstrictor Agents; Vasopressins | 1999 |
Vasopressin(4-9) fragment activates V1a-type vasopressin receptor in rat supraoptic neurones.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Calcium; Fluorescent Dyes; Fura-2; Hormone Antagonists; In Vitro Techniques; Indoles; Male; Morpholines; Neurons; Peptide Fragments; Pyrrolidines; Rats; Rats, Wistar; Receptors, Vasopressin; Spiro Compounds; Supraoptic Nucleus | 1999 |
Vasopressin V2 (SR121463A) and V1a (SR49059) receptor antagonists both inhibit desmopressin vasorelaxing activity.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Aorta; Arginine Vasopressin; Deamino Arginine Vasopressin; Endothelium, Vascular; Hemostatics; Hormone Antagonists; Indoles; Male; Morpholines; Pyrrolidines; Rats; Rats, Wistar; Spiro Compounds | 1999 |
Developmental regulation of a local positive autocontrol of supraoptic neurons.
Topics: Action Potentials; Animals; Electrophysiology; Homeostasis; Hormone Antagonists; In Vitro Techniques; Indoles; Male; Morpholines; Neurons; Oxytocin; Pyrrolidines; Rats; Rats, Wistar; Spiro Compounds; Supraoptic Nucleus; Synapses; Vasopressins | 2000 |
Evidence that atypical vasopressin V(2) receptor in inner medulla of kidney is V(1B) receptor.
Topics: Animals; Benzazepines; Calcium; CHO Cells; Cricetinae; Deamino Arginine Vasopressin; Dose-Response Relationship, Drug; Humans; Indoles; Inositol Phosphates; Kidney Medulla; Morpholines; Pyrrolidines; Rats; Receptors, Vasopressin; Renal Agents; RNA, Messenger; Spiro Compounds; Vasopressins | 2000 |
Interplay between presynaptic and postsynaptic activities is required for dendritic plasticity and synaptogenesis in the supraoptic nucleus.
Topics: Animals; Arginine Vasopressin; Calcium; Dendrites; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Hormone Antagonists; In Vitro Techniques; Indoles; Microinjections; Morpholines; N-Methylaspartate; Neuronal Plasticity; Neurons; Oxytocin; Presynaptic Terminals; Pyrrolidines; Rats; Receptors, N-Methyl-D-Aspartate; Spiro Compounds; Supraoptic Nucleus; Synapses; Synaptic Transmission | 2002 |
Functional rescue of vasopressin V2 receptor mutants in MDCK cells by pharmacochaperones: relevance to therapy of nephrogenic diabetes insipidus.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Antigens, Surface; Binding, Competitive; Blotting, Western; Cell Line; Cell Membrane; Cyclic AMP; Diabetes Insipidus, Nephrogenic; Dogs; Electrophoresis, Polyacrylamide Gel; Green Fluorescent Proteins; Immunohistochemistry; Indoles; Kidney; Molecular Chaperones; Morpholines; Mutation; Pyrrolidines; Receptors, Vasopressin; Spiro Compounds; Transfection | 2007 |
Effects of novel vasopressin receptor antagonists on renal function and cardiac hypertrophy in rats with experimental congestive heart failure.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Body Weight; Cardiomegaly; Disease Models, Animal; Diuresis; Drug Administration Schedule; Heart Failure; Indoles; Kidney Function Tests; Male; Morpholines; Organ Size; Osmolar Concentration; Pyrrolidines; Rats; Rats, Sprague-Dawley; Sodium; Spiro Compounds; Vasoconstriction | 2008 |
Vasopressin-2 receptor antagonist attenuates the ability of the lungs to clear edema in an experimental model.
Topics: Alveolar Epithelial Cells; Amiloride; Animals; Antidiuretic Hormone Receptor Antagonists; Cells, Cultured; Colchicine; In Vitro Techniques; Indoles; Male; Morpholines; Ouabain; Permeability; Pulmonary Alveoli; Pulmonary Edema; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin; Sodium-Potassium-Exchanging ATPase; Spiro Compounds; Vasopressins | 2012 |
Effect of small molecule vasopressin V1a and V2 receptor antagonists on brain edema formation and secondary brain damage following traumatic brain injury in mice.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Brain Edema; Brain Injuries; Disease Models, Animal; Indoles; Male; Mice; Mice, Inbred C57BL; Morpholines; Pyrrolidines; Receptors, Vasopressin; Spiro Compounds | 2015 |
Evaluation of pharmacochaperone-mediated rescue of mutant V2 receptor proteins.
Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Chlorocebus aethiops; COS Cells; Cyclic AMP; Hormone Antagonists; Indoles; Morpholines; Mutation; Pyrrolidines; Receptors, Vasopressin; Spiro Compounds | 2019 |