sarpogrelate has been researched along with ketanserin in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (42.86) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishiguro, M; Launay, JM; Manivet, P; Nagatomo, T; Nishio, H; Pratuangdejkul, J; Rajab, M; Rashid, M | 1 |
| Kimura, M; Kinami, J; Nagatomo, T; Shirota, K; Tsuchihashi, H; Yagi, N | 1 |
| Kinami, J; Maruyama, K; Nagatomo, T; Sugita, Y; Sugiyama, E; Takada, Y; Tsuchihashi, H | 1 |
| Pietraszek, MH; Takada, A; Takada, Y; Taminato, A; Watanabe, I; Yoshimi, T | 1 |
| Asazuma, N; Kume, S; Kurota, K; Ozaki, Y; Qi, R; Satoh, K; Yatomi, Y | 1 |
| Anami, Y; Kasho, M; Kobori, S; Matsuda, H; Matsumura, T; Sakai, M; Sasahara, T; Shichiri, M; Takemura, T | 1 |
| Chen, Z; Morimoto, Y; Nakata, Y; Nishio, H; Yoshikawa, S | 1 |
| Asai, F; Fujimoto, K; Goto, R; Hayakawa, M; Ito, R; Ogawa, T; Sugidachi, A; Tanaka, N | 1 |
| Gong, H; Hattori, K; Nagatomo, T; Nakamura, T; Nakazawa, M; Ohnuki, T; Rashid, M; Watanabe, K | 1 |
| Israilova, M; Muramatsu, I; Nagatomo, T; Suzuki, F; Tanaka, T; Taniguchi, T | 1 |
| Fujii, H; Hirai, T; Nishio, H; Nitanda, A; Tokumo, K; Yasunami, N | 1 |
| Kawakami, J; Komiyama, T; Muntasir, HA; Nagatomo, T; Rashid, M | 1 |
| Balsamo, A; Betti, L; Giannaccini, G; Nencetti, S; Orlandini, E; Rapposelli, S | 1 |
| Choi, HS; Jun, DW; Kim, DC; Kim, EK; Kwon, YI; Lee, HL; Lee, KN; Lee, OY; Yoon, BC | 1 |
14 other study(ies) available for sarpogrelate and ketanserin
| Article | Year |
|---|---|
Identification of the binding sites and selectivity of sarpogrelate, a novel 5-HT2 antagonist, to human 5-HT2A, 5-HT2B and 5-HT2C receptor subtypes by molecular modeling.
Topics: Amino Acid Sequence; Binding Sites; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Sequence Data; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Antagonists; Static Electricity; Succinates | 2003 |
Binding characteristics of [3H]ketanserin for serotonin-2 receptor in the rabbit platelet.
Topics: Animals; Blood Platelets; In Vitro Techniques; Ketanserin; Kinetics; Male; Rabbits; Receptors, Adrenergic, alpha; Receptors, Dopamine; Receptors, Histamine; Receptors, Serotonin; Succinates | 1991 |
MCI-9042: high affinity for serotonergic receptors as assessed by radioligand binding assay.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Brain Chemistry; Clonidine; Hippocampus; In Vitro Techniques; Ketanserin; Kinetics; Platelet Aggregation Inhibitors; Prazosin; Propanolamines; Radioligand Assay; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Muscarinic; Receptors, Serotonin; Succinates | 1991 |
The effect of MCI-9042 on serotonin-induced platelet aggregation in type 2 diabetes mellitus.
Topics: Adult; Aged; Collagen; Diabetes Mellitus, Type 2; Female; Humans; Ketanserin; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin; Serotonin Antagonists; Succinates | 1993 |
Quantitative measurement of various 5-HT receptor antagonists on platelet activation induced by serotonin.
Topics: Blood Platelets; Calcium; Cell Separation; Cell Size; Humans; Ketanserin; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Serotonin; Serotonin Antagonists; Succinates | 1996 |
Serotonin enhances the production of type IV collagen by human mesangial cells.
Topics: Cells, Cultured; Collagen; Diabetic Nephropathies; Glomerular Mesangium; Humans; Ketanserin; Kinetics; Protein Kinase C; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Succinates; Transforming Growth Factor beta | 1998 |
Binding affinity of sarpogrelate to 5-HT(2A) receptor ligand recognition sites in rat renal cortical and mesangial cells in culture.
Topics: Animals; Binding Sites; Binding, Competitive; Cells, Cultured; Cerebral Cortex; DOM 2,5-Dimethoxy-4-Methylamphetamine; Glomerular Mesangium; Ketanserin; Kidney Cortex; Male; Membranes; Radioligand Assay; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Subcellular Fractions; Succinates; Tritium | 1999 |
[2-(omega-phenylalkyl)phenoxy]alkylamines.II: Synthesis and selective serotonin-2 receptor binding.
Topics: Animals; Blood Platelets; Blood Vessels; Humans; In Vitro Techniques; Ketanserin; Phenyl Ethers; Piperidines; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrroles; Rats; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Structure-Activity Relationship; Succinates; Vasoconstriction | 2000 |
A novel 5-HT(2) antagonist, sarpogrelate hydrochloride, shows inhibitory effects on both contraction and relaxation mediated by 5-HT receptor subtypes in porcine coronary arteries.
Topics: Animals; Coronary Vessels; Ergonovine; In Vitro Techniques; Ketanserin; Muscle Contraction; Muscle Relaxation; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Succinates; Swine | 2000 |
Binding and functional affinity of sarpogrelate, its metabolite m-1 and ketanserin for human recombinant alpha-1-adrenoceptor subtypes.
Topics: Adrenergic alpha-Agonists; Animals; Binding, Competitive; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Gene Expression; Humans; Ketanserin; Phenylephrine; Prazosin; Propanolamines; Receptors, Adrenergic, alpha-1; Serotonin Antagonists; Succinates; Tritium | 2002 |
Contribution of the peripheral 5-HT 2A receptor to mechanical hyperalgesia in a rat model of neuropathic pain.
Topics: Animals; Binding Sites; Binding, Competitive; Denervation; Disease Models, Animal; Drug Interactions; Hyperalgesia; Ketanserin; Ligation; Male; Neuralgia; Pain Threshold; Peripheral Nerves; Peripheral Nervous System Diseases; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Sciatic Neuropathy; Sensory Receptor Cells; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Succinates | 2005 |
Identification of amino acid residues important for sarpogrelate binding to the human 5-hydroxytryptamine2A serotonin receptor.
Topics: Amino Acids; Animals; Binding, Competitive; Blotting, Western; Cell Line; Cells, Cultured; Chlorocebus aethiops; COS Cells; DNA; Humans; Inositol Phosphates; Ketanserin; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Receptor, Serotonin, 5-HT2A; Serotonin Antagonists; Serotonin Receptor Agonists; Succinates; Transfection | 2006 |
Synthesis and 5-HT2A, 5-HT1A and alpha1-binding affinities of 2-[2-Hydroxy-3-(pyridin-3-yl-methyl)amino]-, 2-[2-hydroxy-3-(2-pyridin-2-yl-ethyl)amino]- and 2-[2-hydroxy-3-(4-N-methyl-piperazin-1-yl)-amino]propoxybenzaldehyde-O-(substituted) benzyl oximes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Cerebral Cortex; In Vitro Techniques; Ketanserin; Ligands; Molecular Structure; Oximes; Piperazines; Prazosin; Protein Binding; Pyridines; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-1; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Succinates | 2007 |
5-HT2A receptor antagonists inhibit hepatic stellate cell activation and facilitate apoptosis.
Topics: Actins; Animals; Apoptosis; Cell Line; Cell Survival; Collagen Type I; Dose-Response Relationship, Drug; Hepatic Stellate Cells; Humans; Ketanserin; Liver Cirrhosis, Experimental; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Serotonin, 5-HT2A; Ritanserin; RNA, Messenger; Serotonin 5-HT2 Receptor Antagonists; Smad2 Protein; Smad3 Protein; Succinates; Thioacetamide; Time Factors; Transforming Growth Factor beta; Wound Healing | 2013 |