Page last updated: 2024-08-18

sarin and pyridostigmine bromide

sarin has been researched along with pyridostigmine bromide in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19904 (13.33)18.7374
1990's9 (30.00)18.2507
2000's14 (46.67)29.6817
2010's2 (6.67)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Anderson, DR; Harris, LW; Koplovitz, I; Lennox, WJ; Stewart, JR1
Bass, KN; Das Gupta, S; Warnick, JE1
Albuquerque, EX; Deshpande, SS; Kauffman, FC; Rickett, DL; Viana, GB1
Albuquerque, EX; Boyne, AF; Deshpande, SS; Meshul, CK1
Inns, RH; Leadbeater, L; Rylands, JM1
Szinicz, L; Worek, F1
Smith, AP1
Das Gupta, S; Husain, K; Kumar, P; Singh, R; Vijayaraghavan, R1
Koplovitz, I; Stewart, JR1
Blank, JA; Menton, RG; Olson, CT1
Henderson, JD; Spencer, PS; Wilson, BW1
Hänninen, O; Kaliste-Korhonen, E; Raushel, FM; Tuovinen, K1
McDonough, JH; Shih, TM1
Abou-Donia, MB; Abu-Qare, AW1
Abou-Donia, MB; Bullman, SL; Dechkovskaia, AM; Goldstein, LB; Khan, WA1
Coatney, EM; Henderson, JD; Nieberg, PS; Spencer, PS; Wilson, BW1
Breton, P; Buée, J; Calvet, JH; Christin, D; Delamanche, S; Taysse, L1
Newmark, J1
Osumi-Sutherland, D1
Husain, K; Somani, SM1
Chialvo, DR; Huynh, L; Jenden, DJ; Roch, M; Scremin, OU; Shih, TM; Sun, W1
Huynh, L; Jenden, DJ; Roch, M; Scremin, OU; Shih, TM; Sun, W1
Adler, M; Albuquerque, EX; Aracava, Y; Fawcett, WP; Hamilton, TA; Kan, RK; Oliveira, M; Pereira, EF; Randall, WR; Romano, JA1
Kellar, KJ1
Abraham, S; Cohen, G; Dachir, S; Gilat, E; Herskovitz, M; Kapon, J; Levy, A; Raveh, L; Teitelbaum, Z1
Dabisch, PA; Davis, EA; Horsmon, MS; Mioduszewski, RJ1
McDonough, JH; O'Donnell, JC; Shih, TM; Skovira, JW1
Kerr, KJ1
Heeren, T; Krengel, MH; Maule, AL; Proctor, SP; Sullivan, KA; Yee, MK; Zundel, CG1

Reviews

2 review(s) available for sarin and pyridostigmine bromide

ArticleYear
Therapy for nerve agent poisoning.
    Archives of neurology, 2004, Volume: 61, Issue:5

    Topics: Antidotes; Atropine; Chemical Warfare Agents; Humans; Neurotoxicity Syndromes; Neurotoxins; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Soman

2004
Gulf War illness: an overview of events, most prevalent health outcomes, exposures, and clues as to pathogenesis.
    Reviews on environmental health, 2015, Volume: 30, Issue:4

    Topics: Australia; Chemical Warfare Agents; Cholinesterase Inhibitors; Environmental Exposure; Europe; Gulf War; Humans; Mustard Gas; Persian Gulf Syndrome; Pesticides; Prevalence; Pyridostigmine Bromide; Sarin; United States; Veterans

2015

Other Studies

28 other study(ies) available for sarin and pyridostigmine bromide

ArticleYear
Reduction by pyridostigmine pretreatment of the efficacy of atropine and 2-PAM treatment of sarin and VX poisoning in rodents.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1992, Volume: 18, Issue:1

    Topics: Acetylcholinesterase; Animals; Atropine; Cholinesterase Inhibitors; Cholinesterase Reactivators; Female; Guinea Pigs; Male; Mice; Mice, Inbred ICR; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin

1992
Interaction of reversible and irreversible cholinesterase inhibitors on the monosynaptic reflex in neonatal rats.
    Toxicology and applied pharmacology, 1989, Jun-01, Volume: 99, Issue:1

    Topics: Animals; Atropine; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Physostigmine; Pregnancy; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Reflex, Monosynaptic; Sarin; Spinal Cord

1989
Effectiveness of physostigmine as a pretreatment drug for protection of rats from organophosphate poisoning.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 6, Issue:3

    Topics: Acetylcholinesterase; Action Potentials; Animals; Atropine; Body Weight; Brain; Brain Chemistry; Cholinesterases; Female; gamma-Aminobutyric Acid; Muscle Contraction; Muscles; Neostigmine; Organophosphate Poisoning; Physostigmine; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Sarin

1986
Comparison of the ultrastructural myopathy induced by anticholinesterase agents at the end plates of rat soleus and extensor muscles.
    Experimental neurology, 1985, Volume: 89, Issue:1

    Topics: Animals; Behavior, Animal; Cholinesterase Inhibitors; Electrophysiology; Female; Microscopy, Electron; Motor Endplate; Muscular Diseases; Nerve Endings; Neuromuscular Junction; Pyridostigmine Bromide; Rats; Rats, Inbred Strains; Sarin; Soman; Time Factors

1985
Treatment of poisoning by soman.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1985, Volume: 5, Issue:6 Pt 2

    Topics: Animals; Antidotes; Atropine; Carbamates; Diazepam; Guinea Pigs; Male; Motor Activity; Organophosphate Poisoning; Parasympatholytics; Phenylpropionates; Physostigmine; Pyridostigmine Bromide; Sarin; Soman; Time Factors

1985
Cardiorespiratory function in nerve agent poisoned and oxime + atropine treated guinea-pigs: effect of pyridostigmine pretreatment.
    Archives of toxicology, 1995, Volume: 69, Issue:5

    Topics: Animals; Atropine; Cholinesterase Inhibitors; Drug Synergism; Female; Guinea Pigs; Heart Function Tests; Organothiophosphorus Compounds; Oximes; Pyridostigmine Bromide; Respiration; Respiratory Function Tests; Sarin

1995
Treatment of nerve gas poisoning.
    The Medical letter on drugs and therapeutics, 1995, May-12, Volume: 37, Issue:948

    Topics: Anticonvulsants; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Gases; Humans; Organophosphate Poisoning; Organophosphates; Organothiophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Respiratory Protective Devices; Sarin; Soman

1995
Long-term effects of the anticholinesterases sarin and soman on latencies of muscle action potentials in mouse diaphragm muscle.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:3

    Topics: Action Potentials; Animals; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diaphragm; Erythrocytes; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Pralidoxime Compounds; Pyridostigmine Bromide; Respiratory Muscles; Sarin; Soman

1993
Influence of pretreatment of carbamates on dynamic pulmonary mechanics in rats exposed to sarin aerosols.
    Indian journal of physiology and pharmacology, 1993, Volume: 37, Issue:3

    Topics: Aerosols; Animals; Carbamates; Male; Physostigmine; Pyridostigmine Bromide; Rats; Rats, Wistar; Respiratory Mechanics; Sarin

1993
A comparison of the efficacy of HI6 and 2-PAM against soman, tabun, sarin, and VX in the rabbit.
    Toxicology letters, 1994, Feb-15, Volume: 70, Issue:3

    Topics: Animals; Antidotes; Atropine; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diazepam; Lethal Dose 50; Male; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Oximes; Poisoning; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Rabbits; Sarin; Soman; Specific Pathogen-Free Organisms

1994
Neuromuscular effects of low level exposures to Sarin, pyridostigmine, DEET, and chlorpyrifos.
    Drug and chemical toxicology, 1998, Volume: 21 Suppl 1

    Topics: Animals; Behavior, Animal; Chlorpyrifos; DEET; Drug Interactions; Haplorhini; Nervous System Diseases; Pyridostigmine Bromide; Rats; Sarin

1998
Clinical effects of low-level exposures to chemical warfare agents in mice and chickens.
    Drug and chemical toxicology, 1998, Volume: 21 Suppl 1

    Topics: Animals; Chemical Warfare; Chickens; Drug Interactions; Mice; Nervous System Diseases; Neuromuscular Junction; Pyridostigmine Bromide; Sarin; Time Factors

1998
Success of pyridostigmine, physostigmine, eptastigmine and phosphotriesterase treatments in acute sarin intoxication.
    Toxicology, 1999, Jun-15, Volume: 134, Issue:2-3

    Topics: Animals; Antidotes; Aryldialkylphosphatase; Esterases; Lethal Dose 50; Male; Mice; Physostigmine; Pyridostigmine Bromide; Sarin

1999
Efficacy of biperiden and atropine as anticonvulsant treatment for organophosphorus nerve agent intoxication.
    Archives of toxicology, 2000, Volume: 74, Issue:3

    Topics: Animals; Anticonvulsants; Atropine; Biperiden; Cholinesterase Inhibitors; Cholinesterase Reactivators; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Guinea Pigs; Lethal Dose 50; Male; Organophosphates; Organophosphorus Compounds; Pralidoxime Compounds; Pyridostigmine Bromide; Sarin; Seizures; Soman

2000
Combined exposure to sarin and pyridostigmine bromide increased levels of rat urinary 3-nitrotyrosine and 8-hydroxy-2'-deoxyguanosine, biomarkers of oxidative stress.
    Toxicology letters, 2001, Aug-06, Volume: 123, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Biomarkers; Calibration; Chemical Warfare Agents; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Deoxyguanosine; Oxidative Stress; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Sarin; Tyrosine

2001
Sensorimotor deficit and cholinergic changes following coexposure with pyridostigmine bromide and sarin in rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 66, Issue:1

    Topics: Acetylcholinesterase; Animals; Behavior, Animal; Binding, Competitive; Brain; Brain Stem; Butyrylcholinesterase; Cerebral Cortex; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Male; Psychomotor Performance; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic; Sarin

2002
Actions of pyridostigmine and organophosphate agents on chick cells, mice, and chickens.
    Drug and chemical toxicology, 2002, Volume: 25, Issue:2

    Topics: Acetylcholinesterase; Animals; Brain; Cells, Cultured; Chemical Warfare Agents; Chick Embryo; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Combinations; Mice; Neurons; Pyridostigmine Bromide; Sarin

2002
Comparative efficacy of diazepam and avizafone against sarin-induced neuropathology and respiratory failure in guinea pigs: influence of atropine dose.
    Toxicology, 2003, Jun-30, Volume: 188, Issue:2-3

    Topics: Animals; Anticonvulsants; Atropine; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Diazepam; Dipeptides; Drug Interactions; Electroencephalography; Guinea Pigs; Histocytochemistry; Muscarinic Antagonists; Nervous System Diseases; Pralidoxime Compounds; Prodrugs; Pyridostigmine Bromide; Respiratory Insufficiency; Sarin; Seizures

2003
Sick veterans pin hopes on Gulf War inquiry.
    Nature, 2004, Aug-19, Volume: 430, Issue:7002

    Topics: Diarrhea; Headache; Humans; Male; Memory Disorders; Pyridostigmine Bromide; Sarin; Syndrome; Veterans; Warfare

2004
Persistent/delayed toxic effects of low-dose sarin and pyridostigmine under physical stress (exercise) in mice.
    Indian journal of physiology and pharmacology, 2004, Volume: 48, Issue:2

    Topics: Animals; Lipid Peroxidation; Male; Mice; Physical Exertion; Pyridostigmine Bromide; Sarin; Stress, Physiological; Time Factors

2004
Low-dose cholinesterase inhibitors do not induce delayed effects on cerebral blood flow and metabolism.
    Pharmacology, biochemistry, and behavior, 2005, Volume: 80, Issue:4

    Topics: Animals; Autoradiography; Blood Gas Analysis; Blood Pressure; Body Temperature; Brain Chemistry; Cerebrovascular Circulation; Cholinesterase Inhibitors; Cholinesterases; Erythrocytes; Glucose; Hydrogen-Ion Concentration; Male; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Regression Analysis; Sarin

2005
Cerebral acetylcholine and choline contents and turnover following low-dose acetylcholinesterase inhibitors treatment in rats.
    Archives of toxicology, 2006, Volume: 80, Issue:11

    Topics: Acetylcholine; Animals; Brain; Choline; Cholinesterase Inhibitors; Male; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Sarin

2006
Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Aug-29, Volume: 103, Issue:35

    Topics: Acetylcholinesterase; Alkaloids; Animals; Atropine; Behavior, Animal; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Therapy, Combination; Galantamine; Guinea Pigs; Insecticides; Lethal Dose 50; Neurons; Organophosphate Poisoning; Organophosphorus Compounds; Paraoxon; Poisoning; Pyridostigmine Bromide; Sarin; Sesquiterpenes; Soman; Time Factors

2006
Overcoming inhibitions.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Sep-05, Volume: 103, Issue:36

    Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Benzodiazepines; Blood-Brain Barrier; Brain; Chemical Warfare Agents; Cholinesterase Inhibitors; Drug Therapy, Combination; Galantamine; Guinea Pigs; Insecticides; Neurons; Neurotransmitter Agents; Organophosphate Poisoning; Organophosphates; Organophosphorus Compounds; Paraoxon; Pralidoxime Compounds; Pyridostigmine Bromide; Receptors, Cholinergic; Receptors, Muscarinic; Sarin; Seizures; Soman; Time Factors

2006
Extrapolating from animal studies to the efficacy in humans of a pretreatment combination against organophosphate poisoning.
    Archives of toxicology, 2007, Volume: 81, Issue:5

    Topics: Animals; Chemical Warfare Agents; Cholinergic Antagonists; Cyclopentanes; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Infusions, Parenteral; Lethal Dose 50; Male; Metabolic Clearance Rate; Organophosphate Poisoning; Organophosphates; Papio anubis; Poisoning; Pyridostigmine Bromide; Sarin; Species Specificity; Treatment Outcome

2007
Development of miotic cross-tolerance between pyridostigmine and sarin vapor.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2006, Volume: 22, Issue:5

    Topics: Animals; Chemical Warfare Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Tolerance; Male; Miosis; Miotics; Premedication; Pupil; Pyridostigmine Bromide; Rats; Rats, Sprague-Dawley; Sarin

2006
Treatment with tertiary oximes prevents seizures and improves survival following sarin intoxication.
    Journal of molecular neuroscience : MN, 2010, Volume: 40, Issue:1-2

    Topics: Acetylcholinesterase; Animals; Atropine; Brain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Diacetyl; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Guinea Pigs; Injections, Intramuscular; Male; Muscarinic Antagonists; Oximes; Pralidoxime Compounds; Pyridinium Compounds; Pyridostigmine Bromide; Sarin; Seizures; Treatment Outcome; Up-Regulation

2010
Longitudinal Assessment of Health Symptoms in Relation to Neurotoxicant Exposures in 1991 Gulf War Veterans: The Ft. Devens Cohort.
    Journal of occupational and environmental medicine, 2020, Volume: 62, Issue:9

    Topics: Cohort Studies; Gulf War; Humans; Longitudinal Studies; Neurotoxins; Occupational Exposure; Persian Gulf Syndrome; Pyridostigmine Bromide; Sarin; Veterans

2020