Page last updated: 2024-08-18

sarin and isoflurophate

sarin has been researched along with isoflurophate in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199018 (40.00)18.7374
1990's8 (17.78)18.2507
2000's8 (17.78)29.6817
2010's10 (22.22)24.3611
2020's1 (2.22)2.80

Authors

AuthorsStudies
Agnusdei, M; Belinskaya, T; Borriello, M; Brindisi, M; Butini, S; Campiani, G; Catalanotti, B; Fattorusso, C; Fiorini, I; Gemma, S; Nacci, V; Novellino, E; Panico, A; Persico, M; Ros, S; Saxena, A1
Lanks, KW; Lieske, CN; Papirmeister, B1
Fiscus, RR; Karczmar, AG; Van Meter, WG1
Fonnum, F; Lund-Karlsen, R1
Lebbin, C; Waser, PG1
Bhattacharya, R; Das Gupta, S; Dube, SN; Husain, K; Jaiswal, DK; Kumar, D; Pandey, KS; Sikder, AK1
Rosenberg, P; Schupper, H1
Dewey, WL; Tripathi, HL1
Das Gupta, S; Deshpande, SB; Warnick, JE1
Boucher, LJ; Broomfield, CA; Fox-Talbot, MK; Lenz, DE; Little, JS; MacIver, B1
Hänninen, O; Harri, M; Kajovaara, M; Kaliste-Korhonen, E; Ryhänen, R1
Haraldsson, S; Lundberg, S; Marchner, H1
Andersen, RA; Fonnum, F; Malthe-Sørenssen, D; Odden, E1
Lynch, MR; Rice, MA; Robinson, SE1
Flynn, CJ; Wecker, L1
Heath, C; Preston, E1
Davies, DR; Holland, P1
Aghajanian, GK; Crowell, EB; Hayes, AH; Ketchum, JS; Sidell, FR1
Ho, IK; Hoskins, B; Sivam, SP1
De Bisschop, HC; Vranken, MA; Willems, JL1
Das Gupta, S; Husain, K; Pant, SC; Raza, SK; Singh, R1
Hänninen, O; Kaliste-Korhonen, E; Raushel, FM; Tuovinen, K1
Degenhardt-Langelaan, CE; Kientz, CE1
Hänninen, O; Kaliste-Korhonen, E; Tuovinen, K1
Barak, D; Greenblatt, HM; Harel, M; Kryger, G; Millard, CB; Ordentlich, A; Raves, ML; Segall, Y; Shafferman, A; Silman, I; Sussman, JL1
Maxwell, DM; Sweeney, RE1
Popov, BN; Xie, Y1
Barcza, T; Cheng, TC; DeFrank, JJ; Hong, K; Jaing, J; Jaszberenyi, JC; Madec, J; McGuinn, WD; Papahadjopoulos, D; Pei, L; Petrikovics, I; Song, ZH; Sylvester, D; Tamulinas, C; Way, JL; Yin, R1
FLEISHER, JH; HANSA, J; HARRISON, CS; KILLOS, PJ1
Le Guével, E; Moutiers, G; Rodriguez-Dafonte, P; Terrier, F1
Ekström, F; Hörnberg, A; Tunemalm, AK1
Froment, MT; Li, H; Lockridge, O; Masson, P; Nachon, F; Schopfer, LM1
Grigoryan, H; Lockridge, O; Masson, P; Schopfer, LM; Terry, AV; Thompson, CM1
Asojo, O; Carlson, JE; Carr, J; Ding, SJ; Hinrichs, SH; Li, B; Li, Y; Lockridge, O; Masson, P; Nachon, F; Schopfer, LM; Thompson, CM; Tong, L; Xue, W1
Meyerhoff, ME; Meyeroff, ME; Ramanathan, M; Simonian, AL; Wang, L; Wild, JR1
Costero, AM; Gil, S; Gotor, R; Martínez-Máñez, R; Parra, M; Sancenón, F1
Gor, GY; Lee, MT; Neimark, AV; Vishnyakov, A1
Alamneh, Y; Biggemann, L; Costante, M; Doctor, BP; Garcia, G; Nambiar, MP; Nigam, S; Short, R; Soojhawon, I; Valiyaveettil, M1
Brewer, KL; Meggs, WJ; Pekman, L; Troendle, MM1
Field, MJ; Langan, P; Parks, JM; Smith, JC; Wymore, T1
Estévez, J; França, TC; Komives, E; Mangas, I; Radić, Z; Taylor, P; Vilanova, E1
Anslyn, EV; Phillips, ST; Reuther, JF; Sun, X1
Bealer, SL; Dudek, FE; Ekstrand, JJ; Lehmkuhle, MJ; McDonough, JH; Miller-Smith, SM; Scholl, EA1
Alam, SI; Bhattacharya, BK; Chaubey, K; Singh, L; Srivastava, N; Waghmare, CK1
Bouknight, KD; Compton, JR; Guelta, MA; Harvey, SP; Jurkouich, KM; Khavrutskii, IV; Legler, PM1

Other Studies

45 other study(ies) available for sarin and isoflurophate

ArticleYear
Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors.
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Acetylcholinesterase; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Computational Biology; Crystallography, X-Ray; Drug Design; Humans; Models, Molecular; Protein Conformation; Structure-Activity Relationship; Tacrine

2008
Spontaneous reactivation of acetylcholinesterase following organophosphate inhibition. II. Characterization of the reactivating components.
    Biochimica et biophysica acta, 1977, Aug-11, Volume: 483, Issue:2

    Topics: Acetylcholinesterase; Animals; Electrophorus; Enzyme Activation; Isoflurophate; Kinetics; Molecular Weight; Organophosphorus Compounds; Phenylacetates; Sarin; Soman

1977
CNS effects of anticholinesterases in the presence of inhibited cholinesterases.
    Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 231, Issue:2

    Topics: Animals; Atropine; Brain; Cholinesterase Inhibitors; Cholinesterases; Electroencephalography; Electrophysiology; Isoflurophate; Male; Physostigmine; Rabbits; Sarin

1978
The effect of locally applied cholinesterase inhibitors and oximes on the acetylcholinesterase activity in different parts of the guinea-pig eye.
    Acta pharmacologica et toxicologica, 1976, Volume: 38, Issue:4

    Topics: Acetylcholinesterase; Animals; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Eye; Guinea Pigs; Isoflurophate; Obidoxime Chloride; Oculomotor Muscles; Oximes; Paraoxon; Sarin

1976
Studies about the specificity of the histochemical localization of choline acetyltransferase.
    Histochemistry, 1975, Dec-19, Volume: 45, Issue:4

    Topics: Acetone; Acetyl Coenzyme A; Acetylcholinesterase; Acetyltransferases; Animals; Buffers; Central Nervous System; Choline; Choline O-Acetyltransferase; Frozen Sections; Histocytochemistry; Isoflurophate; Lead; Mice; Physostigmine; Sarin

1975
The 3,3'-bis-pyridinium mono-oximes as antidotes against organophosphorous intoxication.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:12

    Topics: Animals; Antidotes; Brain Chemistry; Cholinesterases; Isoflurophate; Male; Mice; Neuromuscular Junction; Oximes; Pyridinium Compounds; Sarin

1992
Effects of diisopropyl phosphofluoridate, sarin and soman on the accessibility of proteins, in the electroplax membrane, to lactoperoxidase-catalyzed iodination.
    Biochemical pharmacology, 1991, Sep-12, Volume: 42, Issue:7

    Topics: Animals; Cell Membrane Permeability; Cholinesterases; Electrophoresis, Polyacrylamide Gel; Electrophorus; In Vitro Techniques; Iodine Radioisotopes; Isoflurophate; Lactoperoxidase; Lipid Bilayers; Macromolecular Substances; Membrane Proteins; Molecular Weight; Proteins; Sarin; Soman

1991
Comparison of the effects of diisopropylfluorophosphate, sarin, soman, and tabun on toxicity and brain acetylcholinesterase activity in mice.
    Journal of toxicology and environmental health, 1989, Volume: 26, Issue:4

    Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Isoflurophate; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Organophosphates; Organophosphorus Compounds; Sarin; Soman

1989
Segmental synaptic depression caused by diisopropylphosphorofluoridate and sarin is reversed by thyrotropin-releasing hormone in the neonatal rat spinal cord.
    Toxicology and applied pharmacology, 1988, Sep-30, Volume: 95, Issue:3

    Topics: Animals; Animals, Newborn; Atropine; Cholinesterases; Isoflurophate; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Reflex, Monosynaptic; Sarin; Spinal Cord; Thyrotropin-Releasing Hormone

1988
Partial characterization of an enzyme that hydrolyzes sarin, soman, tabun, and diisopropyl phosphorofluoridate (DFP).
    Biochemical pharmacology, 1989, Jan-01, Volume: 38, Issue:1

    Topics: Animals; Hydrolases; Hydrolysis; Isoflurophate; Kinetics; Liver; Magnesium; Male; Organophosphates; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Sarin; Soman; Stereoisomerism

1989
Physical exercise affects cholinesterases and organophosphate response.
    General pharmacology, 1988, Volume: 19, Issue:6

    Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Cholinesterases; Diaphragm; In Vitro Techniques; Isoflurophate; Male; Organophosphorus Compounds; Physical Conditioning, Animal; Rats; Rats, Inbred F344; Sarin

1988
Organophosphorus anticholinesterases do not mediate analgesia through inhibition of enkephalin degradation.
    Life sciences, 1986, Apr-07, Volume: 38, Issue:14

    Topics: Acetylcholinesterase; Aminopeptidases; Analgesia; Animals; Brain; Cholinesterase Inhibitors; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalin, Leucine; Enkephalins; Isoflurophate; Male; Neprilysin; Organophosphates; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Sarin; Soman; Synaptosomes

1986
Effects of organophosphates on presynaptic events in the vascularly perfused phrenic nerve-hemidiaphragm preparation from the rat.
    Biochemical pharmacology, 1987, Apr-01, Volume: 36, Issue:7

    Topics: Acetylcholine; Animals; Cholinesterase Inhibitors; Diaphragm; Electric Stimulation; Female; In Vitro Techniques; Isoflurophate; Male; Muscles; Organophosphorus Compounds; Organothiophosphorus Compounds; Perfusion; Phrenic Nerve; Rats; Rats, Inbred Strains; Sarin; Soman; Synapses

1987
Dissociation of locomotor depression and ChE activity after DFP, soman and sarin.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:4

    Topics: Animals; Brain; Brain Mapping; Cholinergic Fibers; Cholinesterases; Corpus Striatum; Isoflurophate; Male; Motor Activity; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Sarin; Soman

1986
Elevated choline levels in brain. A non-cholinergic component of organophosphate toxicity.
    Biochemical pharmacology, 1986, Sep-15, Volume: 35, Issue:18

    Topics: Acetylcholinesterase; Animals; Brain; Choline; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Isoflurophate; Male; Microwaves; Paraoxon; Rats; Rats, Inbred Strains; Sarin; Soman

1986
Atropine-insensitive vasodilatation and hypotension in the organophosphate-poisoned rabbit.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 200, Issue:2

    Topics: Animals; Atropine; Blood Pressure; Blood Vessels; Cholinesterase Inhibitors; Forelimb; Heart Rate; Hypotension; Isoflurophate; Organophosphate Poisoning; Rabbits; Respiration, Artificial; Sarin; Soman; Vascular Resistance; Vasodilator Agents

1972
Effect of oximes and atropine upon the development of delayed neurotoxic signs in chickens following poisoning by DFP and sarin.
    Biochemical pharmacology, 1972, Dec-01, Volume: 21, Issue:23

    Topics: Animals; Atropine; Chickens; Cholinesterase Inhibitors; Isoflurophate; Lethal Dose 50; Neurons; Organophosphorus Compounds; Oximes; Sarin; Time Factors

1972
Atropine, scopolamine, and ditran: comparative pharmacology and antagonists in man.
    Psychopharmacologia, 1973, Jan-01, Volume: 28, Issue:2

    Topics: Acridines; Adult; Atropine; Behavior; Blood Pressure; Central Nervous System; Delirium; Glycolates; Heart Rate; Human Experimentation; Humans; Isoflurophate; Male; Memory; Methylphenidate; Neostigmine; Parasympatholytics; Physostigmine; Piperidines; Respiration; Sarin; Scopolamine

1973
An assessment of comparative acute toxicity of diisopropyl-fluorophosphate, tabun, sarin, and soman in relation to cholinergic and GABAergic enzyme activities in rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1984, Volume: 4, Issue:4

    Topics: 4-Aminobutyrate Transaminase; Animals; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Corpus Striatum; Erythrocytes; gamma-Aminobutyric Acid; In Vitro Techniques; Isoflurophate; Lethal Dose 50; Male; Organophosphates; Organophosphorus Compounds; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Sarin; Soman

1984
"In vitro" inhibition of neurotoxic esterase by organophosphorus nerve agents.
    Archives internationales de pharmacodynamie et de therapie, 1982, Volume: 260, Issue:2

    Topics: Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Isoflurophate; Nervous System Diseases; Organophosphorus Compounds; Sarin

1982
A comparative study of delayed neurotoxicity in hens following repeated administration of organophosphorus compounds.
    Indian journal of physiology and pharmacology, 1995, Volume: 39, Issue:1

    Topics: Animals; Ataxia; Blood Platelets; Brain; Carboxylic Ester Hydrolases; Central Nervous System; Chickens; Cholinesterase Inhibitors; Female; Isoflurophate; Parathion; Sarin; Spinal Cord; Structure-Activity Relationship

1995
Protection of organophosphate-inactivated esterases with phosphotriesterase.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1996, Volume: 31, Issue:2

    Topics: Animals; Aryldialkylphosphatase; Biological Availability; Brain; Cholinesterase Inhibitors; Drug Antagonism; Esterases; Isoflurophate; Lung; Male; Mice; Sarin; Soman; Time Factors

1996
Capillary gas chromatographic analysis of nerve agents using large volume injections.
    Journal of chromatography. A, 1996, Feb-02, Volume: 723, Issue:1

    Topics: Chemical Warfare Agents; Cholinesterase Inhibitors; Chromatography, Gas; Hydrogen-Ion Concentration; Isoflurophate; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Soman; Water

1996
Gender differences in activities of mouse esterase and sensitivities to DFP and sarin toxicity.
    General pharmacology, 1997, Volume: 29, Issue:3

    Topics: Animals; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Cholinesterases; Esterases; Female; Isoflurophate; Male; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Sarin; Sex Characteristics

1997
Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level.
    Biochemistry, 1999, Jun-01, Volume: 38, Issue:22

    Topics: Acetylcholinesterase; Acetylthiocholine; Acylation; Animals; Binding Sites; Butyrylthiocholine; Chemical Warfare Agents; Cholinesterase Inhibitors; Crystallography, X-Ray; Enzyme Activation; Humans; Hydrolysis; Isoflurophate; Kinetics; Models, Molecular; Sarin; Soman; Torpedo

1999
A theoretical model of the competition between hydrolase and carboxylesterase in protection against organophosphorus poisoning.
    Mathematical biosciences, 1999, Volume: 160, Issue:2

    Topics: Acetylcholinesterase; Animals; Aryldialkylphosphatase; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Dichlorvos; Esterases; Isoflurophate; Lethal Dose 50; Models, Biological; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Rats; Sarin; Soman

1999
Catalyzed hydrolysis of nerve gases by metal chelate compounds and potentiometric detection of the byproducts.
    Analytical chemistry, 2000, May-01, Volume: 72, Issue:9

    Topics: Catalysis; Chelating Agents; Chemical Warfare Agents; Cholinesterase Inhibitors; Copper; Hydrolysis; Isoflurophate; Potentiometry; Sarin; Soman

2000
Long circulating liposomes encapsulating organophosphorus acid anhydrolase in diisopropylfluorophosphate antagonism.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 57, Issue:1

    Topics: Animals; Aryldialkylphosphatase; Cholinesterase Inhibitors; Drug Carriers; Esterases; Isoflurophate; Lethal Dose 50; Liposomes; Male; Mice; Mice, Inbred BALB C; Sarin; Soman; Substrate Specificity

2000
Effects of 1,1'-trimethylene bis(4-formylpyridinium bromide) dioxime (TMB-4) on cholinesterase activity and neuromuscular block following poisoning with sarin and DEP.
    The Journal of pharmacology and experimental therapeutics, 1960, Volume: 130

    Topics: Bromides; Cholinesterase Inhibitors; Cyclopropanes; Isoflurophate; Neuromuscular Blockade; Neuromuscular Junction; Phosphates; Pyridines; Pyrrolidines; Sarin; Trimedoxime

1960
Revisiting the reactivity of oximate alpha-nucleophiles with electrophilic phosphorus centers. Relevance to detoxification of sarin, soman and DFP under mild conditions.
    Organic & biomolecular chemistry, 2006, Dec-07, Volume: 4, Issue:23

    Topics: Hydrogen-Ion Concentration; Isoflurophate; Kinetics; Organophosphonates; Organophosphorus Compounds; Oximes; Phenols; Sarin; Soman

2006
Crystal structures of acetylcholinesterase in complex with organophosphorus compounds suggest that the acyl pocket modulates the aging reaction by precluding the formation of the trigonal bipyramidal transition state.
    Biochemistry, 2007, Apr-24, Volume: 46, Issue:16

    Topics: Acetylcholinesterase; Amino Acid Sequence; Animals; Cholinesterase Inhibitors; Histidine; Isoflurophate; Mice; Models, Molecular; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin

2007
Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 100, Issue:1

    Topics: Butyrylcholinesterase; Catalytic Domain; Chemical Warfare Agents; Cholinesterase Inhibitors; Deuterium Oxide; Dichlorvos; Echothiophate Iodide; Enzyme Stability; Humans; Insecticides; Isoflurophate; Malathion; Molecular Structure; Peptide Mapping; Sarin; Serine; Soman; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Trypsin

2007
Mass spectrometry identifies covalent binding of soman, sarin, chlorpyrifos oxon, diisopropyl fluorophosphate, and FP-biotin to tyrosines on tubulin: a potential mechanism of long term toxicity by organophosphorus agents.
    Chemico-biological interactions, 2008, Sep-25, Volume: 175, Issue:1-3

    Topics: Binding Sites; Biotin; Chlorpyrifos; Cholinesterase Inhibitors; Isoflurophate; Organophosphorus Compounds; Sarin; Soman; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tubulin; Tyrosine

2008
Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin.
    Chemical research in toxicology, 2008, Volume: 21, Issue:9

    Topics: Albumins; Biotin; Chlorpyrifos; Chromatography, Liquid; Crystallography, X-Ray; Dichlorvos; Humans; Hydrogen-Ion Concentration; Isoflurophate; Models, Molecular; Molecular Structure; Organophosphorus Compounds; Reproducibility of Results; Sarin; Serine; Soman; Staining and Labeling; Tandem Mass Spectrometry; Tyrosine

2008
Monitoring of diisopropyl fluorophosphate hydrolysis by fluoride-selective polymeric films using absorbance spectroscopy.
    Analytica chimica acta, 2010, May-14, Volume: 667, Issue:1-2

    Topics: Absorption; Biocatalysis; Chemical Warfare Agents; Fluorides; Hydrolysis; Isoflurophate; Phosphoric Monoester Hydrolases; Polymers; Sarin; Soman; Spectrophotometry, Ultraviolet

2010
A molecular probe for the highly selective chromogenic detection of DFP, a mimic of Sarin and Soman nerve agents.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2011, Oct-17, Volume: 17, Issue:43

    Topics: Chemical Warfare Agents; Cholinesterase Inhibitors; Chromogenic Compounds; Isoflurophate; Molecular Probes; Molecular Structure; Sarin; Soman

2011
Interactions of phosphororganic agents with water and components of polyelectrolyte membranes.
    The journal of physical chemistry. B, 2011, Nov-24, Volume: 115, Issue:46

    Topics: Electrolytes; Hydrogen Bonding; Isoflurophate; Lipid Bilayers; Models, Chemical; Organophosphorus Compounds; Polystyrenes; Sarin; Solvents; Soman; Thermodynamics; Water

2011
Hydrolysis potential of recombinant human skin and kidney prolidase against diisopropylfluorophosphate and sarin by in vitro analysis.
    Toxicology in vitro : an international journal published in association with BIBRA, 2012, Volume: 26, Issue:1

    Topics: Acetylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Dipeptidases; Humans; Hydrolysis; Isoflurophate; Kidney; Liver; Organophosphates; Organothiophosphorus Compounds; Recombinant Proteins; Sarin; Skin

2012
Naltrexone prevents delayed encephalopathy in rats poisoned with the sarin analogue diisopropylflurophosphate.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:4

    Topics: Animals; Brain Diseases; Central Nervous System Agents; Cholinesterase Inhibitors; Female; Injections, Intraperitoneal; Isoflurophate; Learning; Memory; Naltrexone; Neurotoxicity Syndromes; Rats; Rats, Long-Evans; Sarin

2013
Hydrolysis of DFP and the nerve agent (S)-sarin by DFPase proceeds along two different reaction pathways: implications for engineering bioscavengers.
    The journal of physical chemistry. B, 2014, May-01, Volume: 118, Issue:17

    Topics: Animals; Chemical Warfare Agents; Hydrolysis; Isoflurophate; Loligo; Models, Molecular; Phosphoric Triester Hydrolases; Protein Conformation; Protein Engineering; Sarin; Thermodynamics

2014
Resolving pathways of interaction of mipafox and a sarin analog with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches.
    Archives of toxicology, 2016, Volume: 90, Issue:3

    Topics: Acetylcholinesterase; Amino Acid Sequence; Catalytic Domain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Humans; Isoflurophate; Kinetics; Models, Molecular; Molecular Sequence Data; Organophosphorus Compounds; Oximes; Paraoxon; Phosphorylation; Protein Conformation; Sarin; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2016
Coupling Activity-Based Detection, Target Amplification, Colorimetric and Fluorometric Signal Amplification, for Quantitative Chemosensing of Fluoride Generated from Nerve Agents.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Mar-17, Volume: 23, Issue:16

    Topics: Colorimetry; Fluorescent Dyes; Fluorides; Isoflurophate; Nerve Agents; Organophosphorus Compounds; Oximes; Phosphates; Sarin; Soman; Spectrometry, Fluorescence

2017
Age-dependent behaviors, seizure severity and neuronal damage in response to nerve agents or the organophosphate DFP in immature and adult rats.
    Neurotoxicology, 2018, Volume: 66

    Topics: Animals; Behavior, Animal; Brain; Female; Isoflurophate; Male; Nerve Agents; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Seizures

2018
Differential proteome analysis of rat plasma after diisopropyl fluorophosphate (DFP) intoxication, a surrogate of nerve agent sarin.
    Chemico-biological interactions, 2019, Jan-25, Volume: 298

    Topics: Animals; Blood Proteins; Cholinesterase Inhibitors; Cholinesterases; Homeostasis; Injections, Subcutaneous; Iron; Isoflurophate; Male; Nerve Agents; Neurotoxicity Syndromes; Oxidative Stress; Rats, Wistar; Reproducibility of Results; Sarin

2019
Structural and kinetic evidence of aging after organophosphate inhibition of human Cathepsin A.
    Biochemical pharmacology, 2020, Volume: 177

    Topics: Acetylcholinesterase; Binding Sites; Cathepsin A; Cell Line; Chemical Warfare Agents; Cholinesterase Inhibitors; Crystallography, X-Ray; Gene Expression; GPI-Linked Proteins; HEK293 Cells; Humans; Isoflurophate; Kinetics; Models, Molecular; Organophosphorus Compounds; Organothiophosphorus Compounds; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; Sarin; Soman; Substrate Specificity; Time Factors

2020
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