sarin and isoflurophate
sarin has been researched along with isoflurophate in 45 studies
Research
Studies (45)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 18 (40.00) | 18.7374 |
1990's | 8 (17.78) | 18.2507 |
2000's | 8 (17.78) | 29.6817 |
2010's | 10 (22.22) | 24.3611 |
2020's | 1 (2.22) | 2.80 |
Authors
Authors | Studies |
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Agnusdei, M; Belinskaya, T; Borriello, M; Brindisi, M; Butini, S; Campiani, G; Catalanotti, B; Fattorusso, C; Fiorini, I; Gemma, S; Nacci, V; Novellino, E; Panico, A; Persico, M; Ros, S; Saxena, A | 1 |
Lanks, KW; Lieske, CN; Papirmeister, B | 1 |
Fiscus, RR; Karczmar, AG; Van Meter, WG | 1 |
Fonnum, F; Lund-Karlsen, R | 1 |
Lebbin, C; Waser, PG | 1 |
Bhattacharya, R; Das Gupta, S; Dube, SN; Husain, K; Jaiswal, DK; Kumar, D; Pandey, KS; Sikder, AK | 1 |
Rosenberg, P; Schupper, H | 1 |
Dewey, WL; Tripathi, HL | 1 |
Das Gupta, S; Deshpande, SB; Warnick, JE | 1 |
Boucher, LJ; Broomfield, CA; Fox-Talbot, MK; Lenz, DE; Little, JS; MacIver, B | 1 |
Hänninen, O; Harri, M; Kajovaara, M; Kaliste-Korhonen, E; Ryhänen, R | 1 |
Haraldsson, S; Lundberg, S; Marchner, H | 1 |
Andersen, RA; Fonnum, F; Malthe-Sørenssen, D; Odden, E | 1 |
Lynch, MR; Rice, MA; Robinson, SE | 1 |
Flynn, CJ; Wecker, L | 1 |
Heath, C; Preston, E | 1 |
Davies, DR; Holland, P | 1 |
Aghajanian, GK; Crowell, EB; Hayes, AH; Ketchum, JS; Sidell, FR | 1 |
Ho, IK; Hoskins, B; Sivam, SP | 1 |
De Bisschop, HC; Vranken, MA; Willems, JL | 1 |
Das Gupta, S; Husain, K; Pant, SC; Raza, SK; Singh, R | 1 |
Hänninen, O; Kaliste-Korhonen, E; Raushel, FM; Tuovinen, K | 1 |
Degenhardt-Langelaan, CE; Kientz, CE | 1 |
Hänninen, O; Kaliste-Korhonen, E; Tuovinen, K | 1 |
Barak, D; Greenblatt, HM; Harel, M; Kryger, G; Millard, CB; Ordentlich, A; Raves, ML; Segall, Y; Shafferman, A; Silman, I; Sussman, JL | 1 |
Maxwell, DM; Sweeney, RE | 1 |
Popov, BN; Xie, Y | 1 |
Barcza, T; Cheng, TC; DeFrank, JJ; Hong, K; Jaing, J; Jaszberenyi, JC; Madec, J; McGuinn, WD; Papahadjopoulos, D; Pei, L; Petrikovics, I; Song, ZH; Sylvester, D; Tamulinas, C; Way, JL; Yin, R | 1 |
FLEISHER, JH; HANSA, J; HARRISON, CS; KILLOS, PJ | 1 |
Le Guével, E; Moutiers, G; Rodriguez-Dafonte, P; Terrier, F | 1 |
Ekström, F; Hörnberg, A; Tunemalm, AK | 1 |
Froment, MT; Li, H; Lockridge, O; Masson, P; Nachon, F; Schopfer, LM | 1 |
Grigoryan, H; Lockridge, O; Masson, P; Schopfer, LM; Terry, AV; Thompson, CM | 1 |
Asojo, O; Carlson, JE; Carr, J; Ding, SJ; Hinrichs, SH; Li, B; Li, Y; Lockridge, O; Masson, P; Nachon, F; Schopfer, LM; Thompson, CM; Tong, L; Xue, W | 1 |
Meyerhoff, ME; Meyeroff, ME; Ramanathan, M; Simonian, AL; Wang, L; Wild, JR | 1 |
Costero, AM; Gil, S; Gotor, R; Martínez-Máñez, R; Parra, M; Sancenón, F | 1 |
Gor, GY; Lee, MT; Neimark, AV; Vishnyakov, A | 1 |
Alamneh, Y; Biggemann, L; Costante, M; Doctor, BP; Garcia, G; Nambiar, MP; Nigam, S; Short, R; Soojhawon, I; Valiyaveettil, M | 1 |
Brewer, KL; Meggs, WJ; Pekman, L; Troendle, MM | 1 |
Field, MJ; Langan, P; Parks, JM; Smith, JC; Wymore, T | 1 |
Estévez, J; França, TC; Komives, E; Mangas, I; Radić, Z; Taylor, P; Vilanova, E | 1 |
Anslyn, EV; Phillips, ST; Reuther, JF; Sun, X | 1 |
Bealer, SL; Dudek, FE; Ekstrand, JJ; Lehmkuhle, MJ; McDonough, JH; Miller-Smith, SM; Scholl, EA | 1 |
Alam, SI; Bhattacharya, BK; Chaubey, K; Singh, L; Srivastava, N; Waghmare, CK | 1 |
Bouknight, KD; Compton, JR; Guelta, MA; Harvey, SP; Jurkouich, KM; Khavrutskii, IV; Legler, PM | 1 |
Other Studies
45 other study(ies) available for sarin and isoflurophate
Article | Year |
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Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors.
Topics: Acetylcholinesterase; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Computational Biology; Crystallography, X-Ray; Drug Design; Humans; Models, Molecular; Protein Conformation; Structure-Activity Relationship; Tacrine | 2008 |
Spontaneous reactivation of acetylcholinesterase following organophosphate inhibition. II. Characterization of the reactivating components.
Topics: Acetylcholinesterase; Animals; Electrophorus; Enzyme Activation; Isoflurophate; Kinetics; Molecular Weight; Organophosphorus Compounds; Phenylacetates; Sarin; Soman | 1977 |
CNS effects of anticholinesterases in the presence of inhibited cholinesterases.
Topics: Animals; Atropine; Brain; Cholinesterase Inhibitors; Cholinesterases; Electroencephalography; Electrophysiology; Isoflurophate; Male; Physostigmine; Rabbits; Sarin | 1978 |
The effect of locally applied cholinesterase inhibitors and oximes on the acetylcholinesterase activity in different parts of the guinea-pig eye.
Topics: Acetylcholinesterase; Animals; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Eye; Guinea Pigs; Isoflurophate; Obidoxime Chloride; Oculomotor Muscles; Oximes; Paraoxon; Sarin | 1976 |
Studies about the specificity of the histochemical localization of choline acetyltransferase.
Topics: Acetone; Acetyl Coenzyme A; Acetylcholinesterase; Acetyltransferases; Animals; Buffers; Central Nervous System; Choline; Choline O-Acetyltransferase; Frozen Sections; Histocytochemistry; Isoflurophate; Lead; Mice; Physostigmine; Sarin | 1975 |
The 3,3'-bis-pyridinium mono-oximes as antidotes against organophosphorous intoxication.
Topics: Animals; Antidotes; Brain Chemistry; Cholinesterases; Isoflurophate; Male; Mice; Neuromuscular Junction; Oximes; Pyridinium Compounds; Sarin | 1992 |
Effects of diisopropyl phosphofluoridate, sarin and soman on the accessibility of proteins, in the electroplax membrane, to lactoperoxidase-catalyzed iodination.
Topics: Animals; Cell Membrane Permeability; Cholinesterases; Electrophoresis, Polyacrylamide Gel; Electrophorus; In Vitro Techniques; Iodine Radioisotopes; Isoflurophate; Lactoperoxidase; Lipid Bilayers; Macromolecular Substances; Membrane Proteins; Molecular Weight; Proteins; Sarin; Soman | 1991 |
Comparison of the effects of diisopropylfluorophosphate, sarin, soman, and tabun on toxicity and brain acetylcholinesterase activity in mice.
Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Isoflurophate; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Organophosphates; Organophosphorus Compounds; Sarin; Soman | 1989 |
Segmental synaptic depression caused by diisopropylphosphorofluoridate and sarin is reversed by thyrotropin-releasing hormone in the neonatal rat spinal cord.
Topics: Animals; Animals, Newborn; Atropine; Cholinesterases; Isoflurophate; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Thyrotropin-Releasing Hormone; Reflex, Monosynaptic; Sarin; Spinal Cord; Thyrotropin-Releasing Hormone | 1988 |
Partial characterization of an enzyme that hydrolyzes sarin, soman, tabun, and diisopropyl phosphorofluoridate (DFP).
Topics: Animals; Hydrolases; Hydrolysis; Isoflurophate; Kinetics; Liver; Magnesium; Male; Organophosphates; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Sarin; Soman; Stereoisomerism | 1989 |
Physical exercise affects cholinesterases and organophosphate response.
Topics: Acetylcholinesterase; Animals; Brain; Cholinesterase Inhibitors; Cholinesterases; Diaphragm; In Vitro Techniques; Isoflurophate; Male; Organophosphorus Compounds; Physical Conditioning, Animal; Rats; Rats, Inbred F344; Sarin | 1988 |
Organophosphorus anticholinesterases do not mediate analgesia through inhibition of enkephalin degradation.
Topics: Acetylcholinesterase; Aminopeptidases; Analgesia; Animals; Brain; Cholinesterase Inhibitors; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Enkephalin, Leucine; Enkephalins; Isoflurophate; Male; Neprilysin; Organophosphates; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Sarin; Soman; Synaptosomes | 1986 |
Effects of organophosphates on presynaptic events in the vascularly perfused phrenic nerve-hemidiaphragm preparation from the rat.
Topics: Acetylcholine; Animals; Cholinesterase Inhibitors; Diaphragm; Electric Stimulation; Female; In Vitro Techniques; Isoflurophate; Male; Muscles; Organophosphorus Compounds; Organothiophosphorus Compounds; Perfusion; Phrenic Nerve; Rats; Rats, Inbred Strains; Sarin; Soman; Synapses | 1987 |
Dissociation of locomotor depression and ChE activity after DFP, soman and sarin.
Topics: Animals; Brain; Brain Mapping; Cholinergic Fibers; Cholinesterases; Corpus Striatum; Isoflurophate; Male; Motor Activity; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Sarin; Soman | 1986 |
Elevated choline levels in brain. A non-cholinergic component of organophosphate toxicity.
Topics: Acetylcholinesterase; Animals; Brain; Choline; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Isoflurophate; Male; Microwaves; Paraoxon; Rats; Rats, Inbred Strains; Sarin; Soman | 1986 |
Atropine-insensitive vasodilatation and hypotension in the organophosphate-poisoned rabbit.
Topics: Animals; Atropine; Blood Pressure; Blood Vessels; Cholinesterase Inhibitors; Forelimb; Heart Rate; Hypotension; Isoflurophate; Organophosphate Poisoning; Rabbits; Respiration, Artificial; Sarin; Soman; Vascular Resistance; Vasodilator Agents | 1972 |
Effect of oximes and atropine upon the development of delayed neurotoxic signs in chickens following poisoning by DFP and sarin.
Topics: Animals; Atropine; Chickens; Cholinesterase Inhibitors; Isoflurophate; Lethal Dose 50; Neurons; Organophosphorus Compounds; Oximes; Sarin; Time Factors | 1972 |
Atropine, scopolamine, and ditran: comparative pharmacology and antagonists in man.
Topics: Acridines; Adult; Atropine; Behavior; Blood Pressure; Central Nervous System; Delirium; Glycolates; Heart Rate; Human Experimentation; Humans; Isoflurophate; Male; Memory; Methylphenidate; Neostigmine; Parasympatholytics; Physostigmine; Piperidines; Respiration; Sarin; Scopolamine | 1973 |
An assessment of comparative acute toxicity of diisopropyl-fluorophosphate, tabun, sarin, and soman in relation to cholinergic and GABAergic enzyme activities in rats.
Topics: 4-Aminobutyrate Transaminase; Animals; Choline O-Acetyltransferase; Cholinesterase Inhibitors; Corpus Striatum; Erythrocytes; gamma-Aminobutyric Acid; In Vitro Techniques; Isoflurophate; Lethal Dose 50; Male; Organophosphates; Organophosphorus Compounds; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Sarin; Soman | 1984 |
"In vitro" inhibition of neurotoxic esterase by organophosphorus nerve agents.
Topics: Animals; Brain; Carboxylic Ester Hydrolases; Chickens; Isoflurophate; Nervous System Diseases; Organophosphorus Compounds; Sarin | 1982 |
A comparative study of delayed neurotoxicity in hens following repeated administration of organophosphorus compounds.
Topics: Animals; Ataxia; Blood Platelets; Brain; Carboxylic Ester Hydrolases; Central Nervous System; Chickens; Cholinesterase Inhibitors; Female; Isoflurophate; Parathion; Sarin; Spinal Cord; Structure-Activity Relationship | 1995 |
Protection of organophosphate-inactivated esterases with phosphotriesterase.
Topics: Animals; Aryldialkylphosphatase; Biological Availability; Brain; Cholinesterase Inhibitors; Drug Antagonism; Esterases; Isoflurophate; Lung; Male; Mice; Sarin; Soman; Time Factors | 1996 |
Capillary gas chromatographic analysis of nerve agents using large volume injections.
Topics: Chemical Warfare Agents; Cholinesterase Inhibitors; Chromatography, Gas; Hydrogen-Ion Concentration; Isoflurophate; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Soman; Water | 1996 |
Gender differences in activities of mouse esterase and sensitivities to DFP and sarin toxicity.
Topics: Animals; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Cholinesterases; Esterases; Female; Isoflurophate; Male; Mice; Mice, Inbred Strains; Nerve Tissue Proteins; Sarin; Sex Characteristics | 1997 |
Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level.
Topics: Acetylcholinesterase; Acetylthiocholine; Acylation; Animals; Binding Sites; Butyrylthiocholine; Chemical Warfare Agents; Cholinesterase Inhibitors; Crystallography, X-Ray; Enzyme Activation; Humans; Hydrolysis; Isoflurophate; Kinetics; Models, Molecular; Sarin; Soman; Torpedo | 1999 |
A theoretical model of the competition between hydrolase and carboxylesterase in protection against organophosphorus poisoning.
Topics: Acetylcholinesterase; Animals; Aryldialkylphosphatase; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Dichlorvos; Esterases; Isoflurophate; Lethal Dose 50; Models, Biological; Organophosphates; Organophosphorus Compounds; Organothiophosphorus Compounds; Rats; Sarin; Soman | 1999 |
Catalyzed hydrolysis of nerve gases by metal chelate compounds and potentiometric detection of the byproducts.
Topics: Catalysis; Chelating Agents; Chemical Warfare Agents; Cholinesterase Inhibitors; Copper; Hydrolysis; Isoflurophate; Potentiometry; Sarin; Soman | 2000 |
Long circulating liposomes encapsulating organophosphorus acid anhydrolase in diisopropylfluorophosphate antagonism.
Topics: Animals; Aryldialkylphosphatase; Cholinesterase Inhibitors; Drug Carriers; Esterases; Isoflurophate; Lethal Dose 50; Liposomes; Male; Mice; Mice, Inbred BALB C; Sarin; Soman; Substrate Specificity | 2000 |
Effects of 1,1'-trimethylene bis(4-formylpyridinium bromide) dioxime (TMB-4) on cholinesterase activity and neuromuscular block following poisoning with sarin and DEP.
Topics: Bromides; Cholinesterase Inhibitors; Cyclopropanes; Isoflurophate; Neuromuscular Blockade; Neuromuscular Junction; Phosphates; Pyridines; Pyrrolidines; Sarin; Trimedoxime | 1960 |
Revisiting the reactivity of oximate alpha-nucleophiles with electrophilic phosphorus centers. Relevance to detoxification of sarin, soman and DFP under mild conditions.
Topics: Hydrogen-Ion Concentration; Isoflurophate; Kinetics; Organophosphonates; Organophosphorus Compounds; Oximes; Phenols; Sarin; Soman | 2006 |
Crystal structures of acetylcholinesterase in complex with organophosphorus compounds suggest that the acyl pocket modulates the aging reaction by precluding the formation of the trigonal bipyramidal transition state.
Topics: Acetylcholinesterase; Amino Acid Sequence; Animals; Cholinesterase Inhibitors; Histidine; Isoflurophate; Mice; Models, Molecular; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin | 2007 |
Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry.
Topics: Butyrylcholinesterase; Catalytic Domain; Chemical Warfare Agents; Cholinesterase Inhibitors; Deuterium Oxide; Dichlorvos; Echothiophate Iodide; Enzyme Stability; Humans; Insecticides; Isoflurophate; Malathion; Molecular Structure; Peptide Mapping; Sarin; Serine; Soman; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Trypsin | 2007 |
Mass spectrometry identifies covalent binding of soman, sarin, chlorpyrifos oxon, diisopropyl fluorophosphate, and FP-biotin to tyrosines on tubulin: a potential mechanism of long term toxicity by organophosphorus agents.
Topics: Binding Sites; Biotin; Chlorpyrifos; Cholinesterase Inhibitors; Isoflurophate; Organophosphorus Compounds; Sarin; Soman; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tubulin; Tyrosine | 2008 |
Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin.
Topics: Albumins; Biotin; Chlorpyrifos; Chromatography, Liquid; Crystallography, X-Ray; Dichlorvos; Humans; Hydrogen-Ion Concentration; Isoflurophate; Models, Molecular; Molecular Structure; Organophosphorus Compounds; Reproducibility of Results; Sarin; Serine; Soman; Staining and Labeling; Tandem Mass Spectrometry; Tyrosine | 2008 |
Monitoring of diisopropyl fluorophosphate hydrolysis by fluoride-selective polymeric films using absorbance spectroscopy.
Topics: Absorption; Biocatalysis; Chemical Warfare Agents; Fluorides; Hydrolysis; Isoflurophate; Phosphoric Monoester Hydrolases; Polymers; Sarin; Soman; Spectrophotometry, Ultraviolet | 2010 |
A molecular probe for the highly selective chromogenic detection of DFP, a mimic of Sarin and Soman nerve agents.
Topics: Chemical Warfare Agents; Cholinesterase Inhibitors; Chromogenic Compounds; Isoflurophate; Molecular Probes; Molecular Structure; Sarin; Soman | 2011 |
Interactions of phosphororganic agents with water and components of polyelectrolyte membranes.
Topics: Electrolytes; Hydrogen Bonding; Isoflurophate; Lipid Bilayers; Models, Chemical; Organophosphorus Compounds; Polystyrenes; Sarin; Solvents; Soman; Thermodynamics; Water | 2011 |
Hydrolysis potential of recombinant human skin and kidney prolidase against diisopropylfluorophosphate and sarin by in vitro analysis.
Topics: Acetylcholinesterase; Chemical Warfare Agents; Cholinesterase Inhibitors; Dipeptidases; Humans; Hydrolysis; Isoflurophate; Kidney; Liver; Organophosphates; Organothiophosphorus Compounds; Recombinant Proteins; Sarin; Skin | 2012 |
Naltrexone prevents delayed encephalopathy in rats poisoned with the sarin analogue diisopropylflurophosphate.
Topics: Animals; Brain Diseases; Central Nervous System Agents; Cholinesterase Inhibitors; Female; Injections, Intraperitoneal; Isoflurophate; Learning; Memory; Naltrexone; Neurotoxicity Syndromes; Rats; Rats, Long-Evans; Sarin | 2013 |
Hydrolysis of DFP and the nerve agent (S)-sarin by DFPase proceeds along two different reaction pathways: implications for engineering bioscavengers.
Topics: Animals; Chemical Warfare Agents; Hydrolysis; Isoflurophate; Loligo; Models, Molecular; Phosphoric Triester Hydrolases; Protein Conformation; Protein Engineering; Sarin; Thermodynamics | 2014 |
Resolving pathways of interaction of mipafox and a sarin analog with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches.
Topics: Acetylcholinesterase; Amino Acid Sequence; Catalytic Domain; Cholinesterase Inhibitors; Cholinesterase Reactivators; Humans; Isoflurophate; Kinetics; Models, Molecular; Molecular Sequence Data; Organophosphorus Compounds; Oximes; Paraoxon; Phosphorylation; Protein Conformation; Sarin; Serine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2016 |
Coupling Activity-Based Detection, Target Amplification, Colorimetric and Fluorometric Signal Amplification, for Quantitative Chemosensing of Fluoride Generated from Nerve Agents.
Topics: Colorimetry; Fluorescent Dyes; Fluorides; Isoflurophate; Nerve Agents; Organophosphorus Compounds; Oximes; Phosphates; Sarin; Soman; Spectrometry, Fluorescence | 2017 |
Age-dependent behaviors, seizure severity and neuronal damage in response to nerve agents or the organophosphate DFP in immature and adult rats.
Topics: Animals; Behavior, Animal; Brain; Female; Isoflurophate; Male; Nerve Agents; Organophosphorus Compounds; Organothiophosphorus Compounds; Sarin; Seizures | 2018 |
Differential proteome analysis of rat plasma after diisopropyl fluorophosphate (DFP) intoxication, a surrogate of nerve agent sarin.
Topics: Animals; Blood Proteins; Cholinesterase Inhibitors; Cholinesterases; Homeostasis; Injections, Subcutaneous; Iron; Isoflurophate; Male; Nerve Agents; Neurotoxicity Syndromes; Oxidative Stress; Rats, Wistar; Reproducibility of Results; Sarin | 2019 |
Structural and kinetic evidence of aging after organophosphate inhibition of human Cathepsin A.
Topics: Acetylcholinesterase; Binding Sites; Cathepsin A; Cell Line; Chemical Warfare Agents; Cholinesterase Inhibitors; Crystallography, X-Ray; Gene Expression; GPI-Linked Proteins; HEK293 Cells; Humans; Isoflurophate; Kinetics; Models, Molecular; Organophosphorus Compounds; Organothiophosphorus Compounds; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; Sarin; Soman; Substrate Specificity; Time Factors | 2020 |