sarcosine and serine

sarcosine has been researched along with serine in 55 studies

Research

Studies (55)

TimeframeStudies, this research(%)All Research%
pre-199021 (38.18)18.7374
1990's0 (0.00)18.2507
2000's14 (25.45)29.6817
2010's17 (30.91)24.3611
2020's3 (5.45)2.80

Authors

AuthorsStudies
Brandsch, M; Gebauer, S; Laug, L; Schäfer, S; Thondorf, I; Voigt, V; Zebisch, K1
Frisell, WR; Lewis, KF; Nemeth, E; Randolph, VM1
Canfield, CJ; McCormick, GJ; Smith, CC1
Benevenga, NJ; Mitchell, AD1
Barbeau, A; Beroniade, V; Breton, G; Geoffroy, G; Lemieux, B; Melançon, S; Shapcott, D1
Braymer, HD; Shinabarger, DL1
Brosnan, JT; Hall, DE; Jois, M1
Mebus, CA; Welsch, F; Working, PK1
Mebus, CA; Welsch, F1
Appling, DR; Barlowe, CK1
Frisell, WR; Randolph, VM2
Mäntsälä, P1
Buchs, S1
Danks, DM; Tippett, P1
Bose, AK; Hungund, BL; Khanchandani, KS1
Damian, AC; MacLeod, MB; Pitts, RF1
Frisell, WR1
Daniels, VG; Newey, H; Smyth, DH1
Efron, ML; Mechanic, GL; Shih, VE1
Herrera, C; Kang, ES; Seyer, J; Todd, TA1
Chen, L; Muhlhauser, M; Yang, CR1
Haradahira, T; Konno, R; Maeda, J; Nishikawa, T; Okauchi, T; Suhara, T; Suzuki, K; Zhang, MR1
Collakova, E; Goyer, A; Hanson, AD; Johnson, TL; Olsen, LJ; Rhodes, D; Shachar-Hill, Y1
Chang, YC; Chiu, CC; Lane, HY; Liu, YC; Tsai, GE1
Deutsch, SI; Long, KD; Manaye, KF; Mastropaolo, J; Rosse, RB1
Hassel, B; Henjum, S1
Chaki, S; Fujita, Y; Hashimoto, K; Ishima, T; Iyo, M1
Chaki, S; Hashimoto, K; Karasawa, J1
Hammonds, MD; Kee, BS; Shim, SS1
Gonnelli, M; Strambini, GB1
Labrie, V; Lipina, T; Roder, JC1
Bauer, I; Braun, S; Hermanns, H; Krug, S; Lipfert, P; Muth-Selbach, U; Werdehausen, R; Williams, R1
Clapcote, SJ; Labrie, V; Roder, JC1
Honda, M; Nakano, T; Ono, H; Tanabe, M1
Chang, YC; Huang, YJ; Lane, HY; Liao, CH; Lin, CH; Tsai, GE1
Chaki, S; Kaku, A; Shimazaki, T1
Ator, MA; Durkin, JT; Flood, DG; Gasior, M; Kopec, K; Marino, MJ; McKenna, BA; Salvino, JM; Schreiber, J; Zuvich, E1
Jeong, HJ; Vandenberg, RJ; Vaughan, CW1
Chang, WT; Cheng, LY; Cherng, CG; Chuang, JY; Kao, GS; Lee, YS; Yang, FY; Yu, L1
de Groat, WC; Funahashi, Y; Oguchi, T; Yoshikawa, S; Yoshimura, N1
Camp, M; Debrouse, L; Grant, SG; Gunduz-Cinar, O; Holmes, A; Hurd, B; Kiselycznyk, C; Mishina, M; Plitt, A; Todaro, A1
Adarakis, G; Ardanaz, E; Boutron-Ruault, MC; Brennan, P; Bueno-de-Mesquita, B; Chirlaque, MD; Chuang, SC; de Magistris, MS; Dossus, L; Ericson, U; Eussen, SJ; Fredriksen, Å; Gallo, V; Grote, VA; Hustad, S; IJssennagger, N; Johansson, M; Meyer, K; Midttun, Ø; Nilsen, RM; Norat, T; Overvad, K; Peeters, PH; Perquier, F; Plada, M; Redondo, ML; Riboli, E; Ros, MM; Schneede, J; Sieri, S; Sonestedt, E; Teucher, B; Trichopoulou, A; Tumino, R; Ueland, PM; Ulvik, A; van Guelpen, B; Vineis, P; Vollset, SE; Wark, PA; Zamora-Ros, R1
Bjørge, T; de Vogel, S; Gregory, JF; Meyer, K; Nygård, O; Tell, GS; Tretli, S; Ueland, PM; Ulvik, A; Vollset, SE1
Aragon, C; Barthel, F; Bauer, I; Brandenburger, T; Eulenburg, V; Hermanns, H; Schlösser, L; Urban, A; Werdehausen, R1
Chaki, S; Hikichi, H; Kaku, A; Kambe, D; Karasawa, J; Kawaura, K; Kinoshita, K; Koike, H1
Berge, RK; Bjørndal, B; Lysne, V; Nordrehaug, JE; Nygård, O; Skorve, J; Vik, R1
Acton, D; Miles, GB1
Avalos, N; Buczynski, MW; Irimia, C; Laredo, SA; Natividad, LA; Parsons, LH1
Iwai, T; Kuraoka, S; Oyama, M; Tanabe, M; Watanabe, S1
Brosnan, JT; Brosnan, ME; Clow, KA; MacMillan, L; Randell, EW; Tingley, G; Young, SK1
Billiras, RI; Dekeyne, A; Fone, KCF; Gobert, A; Millan, MJ; Rivet, JM; Sicard, DI; Watson, DJG1
Juárez-López, D; Schcolnik-Cabrera, A1
Huang, CC; Lane, HY; Wei, IH; Yang, HT1

Reviews

3 review(s) available for sarcosine and serine

ArticleYear
Amino acid nutrition of the chick--essentiality of proline and glycine biosynthesis.
    Nutrition reviews, 1971, Volume: 29, Issue:1

    Topics: Amination; Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Chickens; Dealkylation; Dietary Proteins; Glycine; Glyoxylates; Growth; Liver; Male; Nutritional Requirements; Proline; Rats; Sarcosine; Serine; Species Specificity; Time Factors

1971
Potentiation of the NMDA receptor in the treatment of schizophrenia: focused on the glycine site.
    European archives of psychiatry and clinical neuroscience, 2008, Volume: 258, Issue:1

    Topics: Acetamides; Alanine; Antipsychotic Agents; Clozapine; Cognition; Cycloserine; Dopamine Agents; Drug Synergism; Drug Therapy, Combination; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Humans; Monoamine Oxidase Inhibitors; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia; Schizophrenic Psychology; Serine

2008
Dual contribution of the mTOR pathway and of the metabolism of amino acids in prostate cancer.
    Cellular oncology (Dordrecht), 2022, Volume: 45, Issue:5

    Topics: Amino Acids; Arginine; Carbohydrates; Glutamine; Humans; Leucine; Lipids; Male; Proline; Prostatic Neoplasms; Sarcosine; Serine; TOR Serine-Threonine Kinases

2022

Trials

2 trial(s) available for sarcosine and serine

ArticleYear
Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study.
    Archives of general psychiatry, 2005, Volume: 62, Issue:11

    Topics: Acute Disease; Adult; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Placebos; Psychiatric Status Rating Scales; Risperidone; Sarcosine; Schizophrenia; Schizophrenic Psychology; Serine; Stereoisomerism; Treatment Outcome

2005
A randomized, double-blind, placebo-controlled comparison study of sarcosine (N-methylglycine) and D-serine add-on treatment for schizophrenia.
    The international journal of neuropsychopharmacology, 2010, Volume: 13, Issue:4

    Topics: Activities of Daily Living; Adult; Antipsychotic Agents; Chronic Disease; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Placebos; Quality of Life; Sarcosine; Schizophrenia; Schizophrenic Psychology; Serine; Stereoisomerism

2010

Other Studies

50 other study(ies) available for sarcosine and serine

ArticleYear
Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1).
    Bioorganic & medicinal chemistry, 2011, Nov-01, Volume: 19, Issue:21

    Topics: Amino Acid Transport Systems; Caco-2 Cells; Endocytosis; Humans; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters

2011
Oxidation of one-carbon compounds to formate and carbon dioxide in rat liver mitochondria.
    Archives of biochemistry and biophysics, 1978, Jan-30, Volume: 185, Issue:2

    Topics: Animals; Carbon Dioxide; Diphosphates; Edetic Acid; Formates; Formyltetrahydrofolates; Glycine; Magnesium; Mitochondria, Liver; Phosphates; Rats; S-Adenosylmethionine; Sarcosine; Serine

1978
Plasmodium knowlesi: in vitro biosynthesis of methionine and thymidylic acid.
    Experimental parasitology, 1977, Volume: 43, Issue:1

    Topics: Animals; Betaine; Cells, Cultured; Choline; Erythrocytes; Folic Acid; Formaldehyde; Formyltetrahydrofolates; Haplorhini; Histidine; Homocysteine; Macaca mulatta; Methionine; Plasmodium; Sarcosine; Serine; Thymidine Monophosphate; Thymine Nucleotides

1977
Importance of sarcosine formation in methionine methyl carbon oxidation in the rat.
    The Journal of nutrition, 1976, Volume: 106, Issue:12

    Topics: Acetates; Animals; Carbon Dioxide; Dose-Response Relationship, Drug; Glycine; Liver; Male; Methionine; Oxidation-Reduction; Rats; Sarcosine; Serine; Urine

1976
Amino acid metabolism in Friedreich's ataxia.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1976, Volume: 3, Issue:4

    Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Friedreich Ataxia; Glycine; Histidine; Humans; Isoleucine; Ornithine; Phenylalanine; Phosphatidylethanolamines; Sarcosine; Serine; Taurine; Tyrosine; Valine

1976
Glyphosate catabolism by Pseudomonas sp. strain PG2982.
    Journal of bacteriology, 1986, Volume: 168, Issue:2

    Topics: Adenine; Bacterial Proteins; Formaldehyde; Formates; Glycine; Glyphosate; Guanine; Methionine; Oxidoreductases, N-Demethylating; Pseudomonas; Sarcosine; Sarcosine Oxidase; Serine

1986
Serine synthesis by the rat kidney.
    Contributions to nephrology, 1988, Volume: 63

    Topics: Animals; Glycine; In Vitro Techniques; Kidney; Rats; Sarcosine; Serine

1988
Attenuation of 2-methoxyethanol-induced testicular toxicity in the rat by simple physiological compounds.
    Toxicology and applied pharmacology, 1989, Jun-01, Volume: 99, Issue:1

    Topics: Animals; Drug Interactions; Ethylene Glycols; Glucose; Glycine; Male; Organ Size; Rats; Rats, Inbred F344; Sarcosine; Serine; Spermatogenesis; Testis

1989
The possible role of one-carbon moieties in 2-methoxyethanol and 2-methoxyacetic acid-induced developmental toxicity.
    Toxicology and applied pharmacology, 1989, Jun-01, Volume: 99, Issue:1

    Topics: Abnormalities, Drug-Induced; Acetates; Animals; Carbon; Ethylene Glycols; Female; Humans; Male; Mice; Oxidation-Reduction; Pregnancy; Sarcosine; Serine; Solvents; Toes

1989
In vitro evidence for the involvement of mitochondrial folate metabolism in the supply of cytoplasmic one-carbon units.
    BioFactors (Oxford, England), 1988, Volume: 1, Issue:2

    Topics: Animals; Cytosol; Folic Acid; Formates; Hypoxanthine; Hypoxanthines; Kinetics; Liver; Mitochondria, Liver; Rats; Rats, Inbred Strains; Sarcosine; Serine; Submitochondrial Particles

1988
Effect of adenine nucleotides on the oxidation of methyl groups in liver mitochondria.
    Biochimica et biophysica acta, 1973, Feb-22, Volume: 292, Issue:2

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Animals; Carbon Dioxide; Dinitrophenols; Folic Acid; Formaldehyde; Formates; Glycine; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methylation; Mitochondria, Liver; Mitochondrial Swelling; NAD; NADP; Oxygen Consumption; Rats; Rotenone; Sarcosine; Semicarbazides; Serine

1973
Correlations between pantothenate uptake, phospholipid synthesis and pantothenate-binding protein formation in Pseudomonas fluorescens P-2.
    Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1974, Volume: 28, Issue:1

    Topics: Carbon Radioisotopes; Cell Membrane; Chloramphenicol; Choline; Chromatography, Gel; Chromatography, Thin Layer; Depression, Chemical; Dialysis; Ethanolamines; Glucose; Glycerol; Glyoxylates; Pantothenic Acid; Phospholipids; Phosphorus; Phosphorus Radioisotopes; Protein Biosynthesis; Protoplasts; Pseudomonas fluorescens; Sarcosine; Serine; Time Factors

1974
N-methyl oxidation in liver mitochondria of triiodothyronine-treated and thyroidectomized rats.
    Biochimica et biophysica acta, 1974, May-22, Volume: 347, Issue:2

    Topics: Adenosine Diphosphate; Animals; Carbon Radioisotopes; Choline; Electron Transport; Formaldehyde; Glycerophosphates; Mitochondria, Liver; Oxidative Phosphorylation; Oxidoreductases, N-Demethylating; Oxygen Consumption; Sarcosine; Serine; Succinates; Thyroid Gland; Thyroidectomy; Time Factors; Triiodothyronine

1974
[Why does the gastric mucosa secrete pepsins and hydrochloric acid? (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Volume: 99, Issue:8

    Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Carbohydrate Metabolism; Cholecystokinin; Dogs; Feedback; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Glycine; Hydrogen-Ion Concentration; Hydrolysis; In Vitro Techniques; Lipid Metabolism; Pepsin A; Peptide Hydrolases; Peptides; Proteins; Sarcosine; Serine; Stimulation, Chemical; Time Factors; Transfer RNA Aminoacylation; Trypsin

1974
The clinical and biochemical findings in three cases of hypersarcosinemia and one case of transient hypersarcosinuria associated with folic acid deficiency.
    Helvetica paediatrica acta, 1974, Volume: 29, Issue:3

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Anemia, Macrocytic; Electrophoresis; Female; Folic Acid Deficiency; Glycine; Humans; Infant; Intellectual Disability; Malabsorption Syndromes; Male; Sarcosine; Serine

1974
The role of glycine in the biosynthesis of a terpene.
    Experientia, 1971, Dec-15, Volume: 27, Issue:12

    Topics: Acetates; Autoradiography; Carbon Isotopes; Formates; Fungi; Glycine; Methionine; Sarcosine; Serine; Terpenes

1971
Synthesis of serine by rat kidney in vivo and in vitro.
    The American journal of physiology, 1970, Volume: 219, Issue:3

    Topics: Animals; Carbon Isotopes; Chromatography; Glucose; Glutamates; Glutamine; Glycerol; Glycine; In Vitro Techniques; Kidney; Male; Rats; Sarcosine; Serine; Time Factors; Transferases

1970
One-carbon metabolism in microorganisms. I. Oxidative demethylation in a sarcosine-utilizing bacterium.
    Archives of biochemistry and biophysics, 1971, Volume: 142, Issue:1

    Topics: Bacteria; Carbon Dioxide; Carbon Isotopes; Cytochromes; Electron Transport; Flavins; Fluorescence; Formaldehyde; Glycine; Hydrolases; Imines; Iron; Oxidation-Reduction; Oxidoreductases; Phenazines; Pigments, Biological; Quaternary Ammonium Compounds; Quinones; Sarcosine; Serine; Soil Microbiology; Spectrophotometry; Sulfates; Ultracentrifugation; Vibration

1971
Stereochemical specificity of neutral amino acid transfer systems in rat small intestine.
    Biochimica et biophysica acta, 1969, Volume: 183, Issue:3

    Topics: Alanine; Amino Acids; Animals; Biological Transport; Carbon Isotopes; Cysteine; Hydroxyproline; Ileum; Intestine, Small; Jejunum; Leucine; Methionine; Pipecolic Acids; Proline; Rats; Sarcosine; Serine; Stereoisomerism

1969
Rapid short-column chromatography of amino acids. A method for blood and urine specimens in the diagnosis and treatment of metabolic disease.
    Analytical biochemistry, 1967, Volume: 20, Issue:2

    Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Aminobutyrates; Autoanalysis; Buffers; Chromatography, Ion Exchange; Citrates; Cysteine; Cystine; Glutamates; Glutamine; Glycine; Humans; Hydrogen-Ion Concentration; Hydroxyproline; Isoleucine; Phenylalanine; Proline; Sarcosine; Serine; Threonine; Tyrosine; Valine

1967
Variability in the phenotypic expression of abnormal sarcosine metabolism in a family.
    Human genetics, 1983, Volume: 64, Issue:1

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Child, Preschool; Female; Genetic Variation; Glycine; Humans; Intellectual Disability; Male; Phenotype; Sarcosine; Serine

1983
Glycine tranporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo.
    Journal of neurophysiology, 2003, Volume: 89, Issue:2

    Topics: Amino Acid Transport Systems, Neutral; Animals; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; Glycine Plasma Membrane Transport Proteins; Iontophoresis; Male; N-Methylaspartate; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Prefrontal Cortex; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine

2003
Effects of endogenous agonists, glycine and D-serine, on in vivo specific binding of [11C]L-703,717, a PET radioligand for the glycine-binding site of NMDA receptors.
    Synapse (New York, N.Y.), 2003, Volume: 50, Issue:2

    Topics: Amino Acid Transport Systems, Neutral; Animals; Binding Sites; Binding, Competitive; Carbon Radioisotopes; Cerebellum; D-Amino-Acid Oxidase; Extracellular Fluid; Glycine; Glycine Plasma Membrane Transport Proteins; Hydroxyquinolines; Ligands; Male; Mice; Mice, Knockout; Neurons; Quinolones; Radioligand Assay; Radionuclide Imaging; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Stereoisomerism; Synaptic Transmission; Up-Regulation

2003
Characterization and metabolic function of a peroxisomal sarcosine and pipecolate oxidase from Arabidopsis.
    The Journal of biological chemistry, 2004, Apr-23, Volume: 279, Issue:17

    Topics: Amino Acid Sequence; Arabidopsis; Cucurbita; Cysteine; DNA, Complementary; Escherichia coli; Formaldehyde; Gas Chromatography-Mass Spectrometry; Glycine; Hydrogen Peroxide; Mass Spectrometry; Microbodies; Models, Chemical; Molecular Sequence Data; Nitrogen; Oxidoreductases Acting on CH-NH Group Donors; Oxygen; Peroxisomes; Protein Structure, Tertiary; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; RNA, Messenger; Sarcosine; Sequence Homology, Amino Acid; Serine; Spectrometry, Mass, Electrospray Ionization; Tetrahydrofolates

2004
Modulatory effects of d-serine and sarcosine on NMDA receptor-mediated neurotransmission are apparent after stress in the genetically inbred BALB/c mouse strain.
    Brain research bulletin, 2006, May-31, Volume: 69, Issue:6

    Topics: Analysis of Variance; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Excitatory Amino Acid Antagonists; Male; Mice; Mice, Inbred BALB C; Receptors, N-Methyl-D-Aspartate; Sarcosine; Seizures; Serine; Stress, Physiological; Synaptic Transmission

2006
High-affinity glycine and glutamate transport in pig forebrain white and gray matter: a quantitative study.
    Neurochemistry international, 2007, Volume: 50, Issue:5

    Topics: Animals; Biological Transport; Excitatory Amino Acid Transporter 2; Glutamate-Ammonia Ligase; Glutamic Acid; Glutaminase; Glutamine; Glutathione; Glycine; Glycine Hydroxymethyltransferase; Glycine Plasma Membrane Transport Proteins; Kainic Acid; Prosencephalon; Sarcosine; Serine; Swine

2007
Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the glycine transporter-1 inhibitor NFPS and D-serine.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2008, Volume: 18, Issue:6

    Topics: Animals; Brain; Brain Chemistry; Cognition Disorders; Disease Models, Animal; Drug Administration Schedule; Drug Interactions; Gene Expression Regulation; Glycine Plasma Membrane Transport Proteins; Male; Mice; Mice, Inbred ICR; Microdialysis; Neuropsychological Tests; Pattern Recognition, Visual; Polycyclic Compounds; Sarcosine; Serine

2008
D-Serine and a glycine transporter inhibitor improve MK-801-induced cognitive deficits in a novel object recognition test in rats.
    Behavioural brain research, 2008, Jan-10, Volume: 186, Issue:1

    Topics: Analysis of Variance; Animals; Antipsychotic Agents; Clozapine; Cognition; Cognition Disorders; Dizocilpine Maleate; Exploratory Behavior; Glycine Plasma Membrane Transport Proteins; Haloperidol; Male; Nootropic Agents; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Sarcosine; Serine; Statistics, Nonparametric

2008
Singular efficacy of trimethylamine N-oxide to counter protein destabilization in ice.
    Biochemistry, 2008, Mar-18, Volume: 47, Issue:11

    Topics: Azurin; Betaine; Cysteine; Freeze Drying; Ice; Methylamines; Osmolar Concentration; Oxidants; Protein Denaturation; Protein Folding; Pseudomonas aeruginosa; Sarcosine; Serine; Solutions; Thermodynamics

2008
Mice with reduced NMDA receptor glycine affinity model some of the negative and cognitive symptoms of schizophrenia.
    Psychopharmacology, 2008, Volume: 200, Issue:2

    Topics: Animals; Behavior, Animal; Carrier Proteins; Clozapine; Disease Models, Animal; Glycine; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nerve Tissue Proteins; Phenotype; Quinolones; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Sarcosine; Schizophrenia; Schizophrenic Psychology; Serine; Social Behavior; Space Perception

2008
Differential effects of spinally applied glycine transporter inhibitors on nociception in a rat model of neuropathic pain.
    Neuroscience letters, 2008, Nov-21, Volume: 445, Issue:3

    Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Functional Laterality; Glycine Plasma Membrane Transport Proteins; Injections, Spinal; Male; Pain Measurement; Rats; Reaction Time; Sarcosine; Sciatica; Serine

2008
Mutant mice with reduced NMDA-NR1 glycine affinity or lack of D-amino acid oxidase function exhibit altered anxiety-like behaviors.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 91, Issue:4

    Topics: Animals; Antipsychotic Agents; Anxiety; Carrier Proteins; D-Amino-Acid Oxidase; Female; Glycine; Male; Maze Learning; Mice; Mice, Inbred C57BL; Motor Activity; Mutation; Nerve Tissue Proteins; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Social Behavior; Space Perception

2009
Glycine transporter blockade ameliorates motor ataxia in a mouse model of spinocerebellar atrophy.
    Journal of pharmacological sciences, 2009, Volume: 109, Issue:3

    Topics: Animals; Binding Sites; Cytarabine; Disease Models, Animal; Dose-Response Relationship, Drug; Glycine; Glycine Plasma Membrane Transport Proteins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Spinocerebellar Ataxias

2009
D-Serine and a glycine transporter-1 inhibitor enhance social memory in rats.
    Psychopharmacology, 2010, Volume: 209, Issue:3

    Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Glycine Plasma Membrane Transport Proteins; Haloperidol; Male; Memory; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Social Behavior; Time Factors

2010
Glycine transporter (GlyT1) inhibitors with reduced residence time increase prepulse inhibition without inducing hyperlocomotion in DBA/2 mice.
    Biochemical pharmacology, 2010, Nov-01, Volume: 80, Issue:9

    Topics: Animals; Glycine; Glycine Plasma Membrane Transport Proteins; Male; Mice; Mice, Inbred DBA; Motor Activity; Neural Inhibition; Sarcosine; Serine; Strychnine; Time Factors

2010
N-arachidonyl-glycine modulates synaptic transmission in superficial dorsal horn.
    British journal of pharmacology, 2010, Volume: 161, Issue:4

    Topics: Animals; Arachidonic Acids; Glycine; Inhibitory Postsynaptic Potentials; Miniature Postsynaptic Potentials; N-Methylaspartate; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Sarcosine; Serine; Spinal Cord; Synaptic Transmission

2010
D-cycloserine, sarcosine and D-serine diminish the expression of cocaine-induced conditioned place preference.
    Journal of psychopharmacology (Oxford, England), 2013, Volume: 27, Issue:6

    Topics: Animals; Behavior, Animal; Cocaine; Conditioning, Psychological; Cycloserine; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Memory; Mice; Mice, Inbred C57BL; Sarcosine; Serine; Time Factors

2013
Glycine transporter type 2 (GlyT2) inhibitor ameliorates bladder overactivity and nociceptive behavior in rats.
    European urology, 2012, Volume: 62, Issue:4

    Topics: Animals; Diterpenes; Female; Freezing Reaction, Cataleptic; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Nociceptive Pain; Pain; Rats; Rats, Sprague-Dawley; Sarcosine; Serine; Spinal Cord; Strychnine; Urinary Bladder, Overactive; Urination

2012
Probing the modulation of acute ethanol intoxication by pharmacological manipulation of the NMDAR glycine co-agonist site.
    Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:2

    Topics: Alcoholic Intoxication; Animals; Ataxia; Cycloserine; Disease Models, Animal; Disks Large Homolog 4 Protein; Dizocilpine Maleate; Drug Therapy, Combination; Glycine Plasma Membrane Transport Proteins; Guanylate Kinases; Hypothermia; Kynurenic Acid; Magnesium; Male; Membrane Proteins; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Quinolones; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex, Righting; Sarcosine; Serine

2013
North-south gradients in plasma concentrations of B-vitamins and other components of one-carbon metabolism in Western Europe: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study.
    The British journal of nutrition, 2013, Jul-28, Volume: 110, Issue:2

    Topics: Adult; Aged; Alcohol Drinking; Chronic Disease; Ethnicity; Europe; Female; Folic Acid; Glycine; Health Behavior; Humans; Life Style; Male; Middle Aged; Prospective Studies; Sarcosine; Serine; Sex Factors; Smoking; Vitamin B 12

2013
Sarcosine and other metabolites along the choline oxidation pathway in relation to prostate cancer--a large nested case-control study within the JANUS cohort in Norway.
    International journal of cancer, 2014, Jan-01, Volume: 134, Issue:1

    Topics: Betaine; Biomarkers, Tumor; Case-Control Studies; Choline; Chromatography, Liquid; Cohort Studies; Glycine; Humans; Male; Mass Spectrometry; Middle Aged; Norway; Oxidation-Reduction; Prostatic Neoplasms; Sarcosine; Serine

2014
Long-term application of glycine transporter inhibitors acts antineuropathic and modulates spinal N-methyl-D-aspartate receptor subunit NR-1 expression in rats.
    Anesthesiology, 2014, Volume: 121, Issue:1

    Topics: Animals; Behavior, Animal; Blotting, Western; Constriction, Pathologic; Dose-Response Relationship, Drug; Glycine Plasma Membrane Transport Proteins; Hyperalgesia; Male; Neuralgia; Pain Measurement; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Spinal Cord

2014
Effects of a glycine transporter-1 inhibitor and D-serine on MK-801-induced immobility in the forced swimming test in rats.
    Behavioural brain research, 2015, Feb-01, Volume: 278

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Clozapine; Disease Models, Animal; Dizocilpine Maleate; Glycine; Glycine Plasma Membrane Transport Proteins; Haloperidol; Imipramine; Locomotion; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia; Serine; Swimming

2015
A Protein Extract from Chicken Reduces Plasma Homocysteine in Rats.
    Nutrients, 2015, Jun-04, Volume: 7, Issue:6

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Caseins; Chickens; Choline; Cystathionine gamma-Lyase; Cysteine; Dietary Proteins; Folic Acid; Glycine; Homocysteine; Liver; Male; Meat; Methionine; Rats; Rats, Wistar; Riboflavin; RNA, Messenger; Sarcosine; Serine; Vitamin B 12; Vitamin B 6

2015
Differential regulation of NMDA receptors by d-serine and glycine in mammalian spinal locomotor networks.
    Journal of neurophysiology, 2017, 05-01, Volume: 117, Issue:5

    Topics: 2-Amino-5-phosphonovalerate; Animals; Efferent Pathways; Glycine; Interneurons; Kynurenic Acid; Mice; Mice, Inbred C57BL; Motor Activity; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Spinal Nerve Roots; Synapses

2017
Dysregulated Glycine Signaling Contributes to Increased Impulsivity during Protracted Alcohol Abstinence.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017, 02-15, Volume: 37, Issue:7

    Topics: Alcohol Abstinence; Alcohol Drinking; Animals; Central Nervous System Depressants; Choice Behavior; Disease Models, Animal; Ethanol; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Glycine; Impulsive Behavior; Male; Neurotransmitter Agents; Photic Stimulation; Quinolones; Rats; Rats, Wistar; Reaction Time; Sarcosine; Serine; Signal Transduction

2017
Electrophysiological evidence of increased glycine receptor-mediated phasic and tonic inhibition by blockade of glycine transporters in spinal superficial dorsal horn neurons of adult mice.
    Journal of pharmacological sciences, 2017, Volume: 133, Issue:3

    Topics: Animals; Glycine Plasma Membrane Transport Proteins; Inhibitory Postsynaptic Potentials; Male; Mice; Posterior Horn Cells; Sarcosine; Serine

2017
Cobalamin Deficiency Results in Increased Production of Formate Secondary to Decreased Mitochondrial Oxidation of One-Carbon Units in Rats.
    The Journal of nutrition, 2018, 03-01, Volume: 148, Issue:3

    Topics: Animals; Carbon; Carbon Dioxide; Cytosol; Folic Acid; Formates; Glycine; Liver; Male; Mitochondria, Liver; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Random Allocation; Rats, Sprague-Dawley; S-Adenosylmethionine; Sarcosine; Serine; Vitamin B 12; Vitamin B 12 Deficiency

2018
Comparative Pro-cognitive and Neurochemical Profiles of Glycine Modulatory Site Agonists and Glycine Reuptake Inhibitors in the Rat: Potential Relevance to Cognitive Dysfunction and Its Management.
    Molecular neurobiology, 2020, Volume: 57, Issue:5

    Topics: Amino Acids; Animals; Autism Spectrum Disorder; Cognition; Cognition Disorders; Cycloserine; Dose-Response Relationship, Drug; Freezing Reaction, Cataleptic; Glycine; Glycine Agents; Male; Memory, Short-Term; Motor Activity; Neurotransmitter Uptake Inhibitors; Nootropic Agents; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Sarcosine; Schizophrenia; Scopolamine; Serine; Social Behavior

2020
Determination of D-serine and D-alanine Tissue Levels in the Prefrontal Cortex and Hippocampus of Rats After a Single Dose of Sodium Benzoate, a D-Amino Acid Oxidase Inhibitor, with Potential Antipsychotic and Antidepressant Properties.
    Neurochemical research, 2023, Volume: 48, Issue:7

    Topics: Alanine; Animals; Antidepressive Agents; Antipsychotic Agents; D-Amino-Acid Oxidase; Hippocampus; Oxidoreductases; Prefrontal Cortex; Rats; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Sodium Benzoate

2023