sarcosine has been researched along with clozapine in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balla, A; Duncan, L; Javitt, DC; Sershen, H | 1 |
| Javitt, DC | 1 |
| Hertel, P; Jardemark, KE; Konradsson, A; Marcus, MM; Svensson, TH | 1 |
| Chang, YC; Chen, PW; Huang, CL; Lane, HY; Lin, PY; Liu, YC; Tsai, G; Wu, PL | 1 |
| Chaki, S; Hashimoto, K; Karasawa, J | 1 |
| Hammonds, MD; Kee, BS; Shim, SS | 1 |
| Labrie, V; Lipina, T; Roder, JC | 1 |
| Chaki, S; Kaku, A; Shimazaki, T | 1 |
| Singh, SP; Singh, V | 1 |
| Chen, CJ; Chen, YM; Fan, A; Hong, CJ; Hsu, CL; Tsai, TH; Wang, HA; Yang, CP | 1 |
| Chaki, S; Hikichi, H; Kaku, A; Kambe, D; Karasawa, J; Kawaura, K; Kinoshita, K; Koike, H | 1 |
3 review(s) available for sarcosine and clozapine
| Article | Year |
|---|---|
Is the glycine site half saturated or half unsaturated? Effects of glutamatergic drugs in schizophrenia patients.
Topics: Antimetabolites; Antipsychotic Agents; Clozapine; Cycloserine; Drug Therapy, Combination; Glutamic Acid; Glycine; Humans; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia | 2006 |
Potentiation of the NMDA receptor in the treatment of schizophrenia: focused on the glycine site.
Topics: Acetamides; Alanine; Antipsychotic Agents; Clozapine; Cognition; Cycloserine; Dopamine Agents; Drug Synergism; Drug Therapy, Combination; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Humans; Monoamine Oxidase Inhibitors; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia; Schizophrenic Psychology; Serine | 2008 |
Meta-analysis of the efficacy of adjunctive NMDA receptor modulators in chronic schizophrenia.
Topics: Adult; Antipsychotic Agents; Clozapine; Drug Therapy, Combination; Glycine; Humans; Middle Aged; Randomized Controlled Trials as Topic; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia; Treatment Outcome | 2011 |
1 trial(s) available for sarcosine and clozapine
| Article | Year |
|---|---|
Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to clozapine for the treatment of schizophrenia.
Topics: Adult; Antipsychotic Agents; Clozapine; Double-Blind Method; Drug Therapy, Combination; Female; Glycine Plasma Membrane Transport Proteins; Humans; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Sarcosine; Schizophrenia; Time Factors; Treatment Outcome | 2006 |
7 other study(ies) available for sarcosine and clozapine
| Article | Year |
|---|---|
Inhibition of system A-mediated glycine transport in cortical synaptosomes by therapeutic concentrations of clozapine: implications for mechanisms of action.
Topics: Amino Acid Transport System A; Amino Acids; Animals; Antipsychotic Agents; beta-Alanine; Cell Line, Tumor; Cerebral Cortex; Clozapine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glioma; Glycine; Hippocampus; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sarcosine; Synaptosomes; Tritium | 2005 |
Inhibition of the glycine transporter GlyT-1 potentiates the effect of risperidone, but not clozapine, on glutamatergic transmission in the rat medial prefrontal cortex.
Topics: Animals; Biological Transport, Active; Clozapine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Male; Organ Culture Techniques; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Risperidone; Sarcosine; Synaptic Transmission | 2006 |
D-Serine and a glycine transporter inhibitor improve MK-801-induced cognitive deficits in a novel object recognition test in rats.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Clozapine; Cognition; Cognition Disorders; Dizocilpine Maleate; Exploratory Behavior; Glycine Plasma Membrane Transport Proteins; Haloperidol; Male; Nootropic Agents; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Sarcosine; Serine; Statistics, Nonparametric | 2008 |
Mice with reduced NMDA receptor glycine affinity model some of the negative and cognitive symptoms of schizophrenia.
Topics: Animals; Behavior, Animal; Carrier Proteins; Clozapine; Disease Models, Animal; Glycine; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nerve Tissue Proteins; Phenotype; Quinolones; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Sarcosine; Schizophrenia; Schizophrenic Psychology; Serine; Social Behavior; Space Perception | 2008 |
D-Serine and a glycine transporter-1 inhibitor enhance social memory in rats.
Topics: Animals; Antipsychotic Agents; Clozapine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Glycine Plasma Membrane Transport Proteins; Haloperidol; Male; Memory; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Social Behavior; Time Factors | 2010 |
Characterization of the neuropsychological phenotype of glycine N-methyltransferase-/- mice and evaluation of its responses to clozapine and sarcosine treatments.
Topics: Animals; Antipsychotic Agents; Clozapine; Crosses, Genetic; Disease Models, Animal; Gene Expression Regulation; Glycine N-Methyltransferase; Humans; Male; Metencephalon; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Organ Specificity; RNA, Messenger; Sarcosine; Schizophrenia; Signal Transduction | 2012 |
Effects of a glycine transporter-1 inhibitor and D-serine on MK-801-induced immobility in the forced swimming test in rats.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Clozapine; Disease Models, Animal; Dizocilpine Maleate; Glycine; Glycine Plasma Membrane Transport Proteins; Haloperidol; Imipramine; Locomotion; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia; Serine; Swimming | 2015 |