sandoz-21-009 has been researched along with bopindolol in 6 studies
| Studies (sandoz-21-009) | Trials (sandoz-21-009) | Recent Studies (post-2010) (sandoz-21-009) | Studies (bopindolol) | Trials (bopindolol) | Recent Studies (post-2010) (bopindolol) |
|---|---|---|---|---|---|
| 19 | 0 | 0 | 131 | 49 | 11 |
| Protein | Taxonomy | sandoz-21-009 (IC50) | bopindolol (IC50) |
|---|---|---|---|
| Beta-2 adrenergic receptor | Homo sapiens (human) | 0.02 | |
| Beta-1 adrenergic receptor | Homo sapiens (human) | 0.047 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 5.4764 | |
| Beta-3 adrenergic receptor | Homo sapiens (human) | 0.458 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.267 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 1.581 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.267 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 1.523 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brasch, H; Dominiak, P | 1 |
| Akashi, H; Hosohata, Y; Kinami, J; Nagatomo, T; Sakuma, N; Tsuchihashi, H | 1 |
| Chin, WP; Imai, S; Kawada, T; Sun, HT | 1 |
| Bobik, A; Jackman, GP; Oddie, CJ | 1 |
| Aniya, Y; Fong, KF; Naito, A; Sakanashi, M | 1 |
| Hosohata, Y; Karakisawa, Y; Maruyama, K; Nagatomo, T; Sasaki, K; Suzuki, M; Tsuchihashi, H | 1 |
6 other study(ies) available for sandoz-21-009 and bopindolol
| Article | Year |
|---|---|
Beta-adrenoceptor blocking effects of two bopindolol metabolites in isolated guinea-pig atria.
Topics: Adrenergic beta-Antagonists; Animals; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Pindolol; Stimulation, Chemical | 1992 |
Beta-blocking potency and selectivity of bopindolol and its two metabolites for beta 1- and beta 2-adrenergic receptors as assessed by radioligand binding assay.
Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Brain; Guinea Pigs; Heart Rate; In Vitro Techniques; Iodocyanopindolol; Kinetics; Muscle Contraction; Myocardium; Pindolol; Propanolamines; Radioligand Assay; Rats; Receptors, Adrenergic, beta; Trachea | 1991 |
[Beta-blocking actions and the partial agonist activity of bopindolol, a new beta-adrenoceptor antagonist, and its two metabolites].
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Myocardial Contraction; Pindolol; Stimulation, Chemical | 1989 |
Analysis of bopindolol and its active metabolite 18-502 in human plasma by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Hypertension; Pindolol; Time Factors | 1983 |
Antioxidative action of the beta-adrenoceptor antagonist bopindolol and its metabolite 18-502.
Topics: Adrenergic beta-Antagonists; Animals; Antioxidants; Dose-Response Relationship, Drug; Lipid Peroxidation; Liver; Male; Microsomes; Pindolol; Propranolol; Rats; Rats, Sprague-Dawley; Signal Transduction; Time Factors | 1995 |
Alpha-1 and beta-adrenergic receptor blocking potencies of bopindolol and its two metabolites (18-502 and 20-785) as assessed by radioligand binding assay methods.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Cattle; Dogs; Heart; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Myocardium; Phenylephrine; Pindolol; Radioligand Assay; Rats; Spleen; Trachea | 1995 |