Page last updated: 2024-09-03

salvinorin a and naloxone

salvinorin a has been researched along with naloxone in 3 studies

Compound Research Comparison

Studies
(salvinorin a)
Trials
(salvinorin a)
Recent Studies (post-2010)
(salvinorin a)
Studies
(naloxone)
Trials
(naloxone)
Recent Studies (post-2010) (naloxone)
247712820,1341,2573,321

Protein Interaction Comparison

ProteinTaxonomysalvinorin a (IC50)naloxone (IC50)
Cytochrome P450 2D6Homo sapiens (human)2
Delta-type opioid receptorMus musculus (house mouse)0.043
Delta-type opioid receptorRattus norvegicus (Norway rat)0.0219
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0019
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0019
Mu-type opioid receptorHomo sapiens (human)0.0397
Delta-type opioid receptorHomo sapiens (human)0.1896
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.05
Kappa-type opioid receptorHomo sapiens (human)0.0795
Mu-type opioid receptorMus musculus (house mouse)0.0154
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.0089
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0055

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Che, T; Kalinin, DV; Loser, K; Mykicki, N; Schepmann, D; Ständer, S; Tangherlini, G; Wünsch, B1
Fantegrossi, WE; Koreeda, M; Kugle, KM; Valdes, LJ; Woods, JH1
Bai, Y; Li, C; Lu, X; Zhang, Y; Zhang, Z; Zhou, Y1

Other Studies

3 other study(ies) available for salvinorin a and naloxone

ArticleYear
Development of Novel Quinoxaline-Based κ-Opioid Receptor Agonists for the Treatment of Neuroinflammation.
    Journal of medicinal chemistry, 2019, 01-24, Volume: 62, Issue:2

    Topics: Animals; Antineoplastic Agents; Binding Sites; Encephalomyelitis, Autoimmune, Experimental; HEK293 Cells; Humans; Interferon-gamma; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Docking Simulation; Protein Structure, Tertiary; Quinoxalines; Receptors, Opioid, kappa; Signal Transduction; Structure-Activity Relationship; Th1 Cells

2019
Kappa-opioid receptor-mediated effects of the plant-derived hallucinogen, salvinorin A, on inverted screen performance in the mouse.
    Behavioural pharmacology, 2005, Volume: 16, Issue:8

    Topics: Analgesics, Opioid; Animals; Behavior, Animal; Benzeneacetamides; Diterpenes; Diterpenes, Clerodane; Hallucinogens; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Piperidines; Psychotropic Drugs; Pyrrolidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Remifentanil

2005
Investigation of the Effects of Opioids on Microglial Nitrite and Nitric Oxide Synthase (iNOS) Production and Phagocytosis during Inflammation.
    Combinatorial chemistry & high throughput screening, 2023, Volume: 26, Issue:10

    Topics: Analgesics, Opioid; Animals; Buprenorphine; Inflammation; Interferon-gamma; Lipopolysaccharides; Mice; Microglia; Naloxone; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Phagocytosis

2023