salvinorin a has been researched along with cocaine in 12 studies
| Studies (salvinorin a) | Trials (salvinorin a) | Recent Studies (post-2010) (salvinorin a) | Studies (cocaine) | Trials (cocaine) | Recent Studies (post-2010) (cocaine) |
|---|---|---|---|---|---|
| 247 | 7 | 128 | 32,461 | 1,096 | 9,400 |
| Protein | Taxonomy | salvinorin a (IC50) | cocaine (IC50) |
|---|---|---|---|
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.338 | |
| Fatty acid-binding protein, heart | Homo sapiens (human) | 0.367 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0855 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0855 | |
| D | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.2861 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.4321 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0855 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.5442 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.8885 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.3796 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 5.541 | |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | 0.2 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.05 | |
| Transporter | Rattus norvegicus (Norway rat) | 3.2277 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Carlezon, WA; Chartoff, EH; Cohen, BM; Damez-Werno, D; Potter, D | 1 |
| Chefer, VI; Gehrke, BJ; Shippenberg, TS | 1 |
| Kivell, B; Morani, AS; Prisinzano, TE; Schenk, S | 1 |
| Carlezon, WA; Chartoff, EH; Cohen, BM; Damez-Werno, D; Potter, DN | 1 |
| Cheng, K; Morrissey, E; Negus, SS; O'Connell, R; Rice, KC | 1 |
| Kivell, BM; Morani, AS; Prisinzano, TE; Schenk, S | 1 |
| Ewald, A; Kivell, BM; Morani, AS; Prevatt-Smith, KM; Prisinzano, TE | 1 |
| Freeman, KB; Naylor, JE; Prisinzano, TE; Woolverton, WL | 1 |
| Baker, PM; Chartoff, EH; Ebner, SR; Potter, D; Ragozzino, ME; Roitman, MF; Sparrow, A | 1 |
| Biggerstaff, A; Crowley, RS; Culverhouse, A; Kivell, BM; Kumar, N; Morani, AS; Paton, KF; Prisinzano, TE; Shepherd, A; Welsh, SA | 1 |
| Freeman, KB; Huskinson, SL; Naylor, JE; Prisinzano, TE; Townsend, EA; Zamarripa, CA | 1 |
| Butelman, ER; Ewald, A; Kivell, BM; Kornberger, L; McElroy, BD; Prisinzano, TE; van de Wetering, R; Welsh, S; Williamson, SE | 1 |
12 other study(ies) available for salvinorin a and cocaine
| Article | Year |
|---|---|
Exposure to the selective kappa-opioid receptor agonist salvinorin A modulates the behavioral and molecular effects of cocaine in rats.
Topics: Animals; Cocaine; Diterpenes, Clerodane; Genes, fos; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Salvia | 2008 |
Effects of acute and repeated administration of salvinorin A on dopamine function in the rat dorsal striatum.
Topics: Animals; Brain Mapping; Cocaine; Corpus Striatum; Diterpenes, Clerodane; Dopamine; Drug Administration Schedule; Drug Interactions; Hallucinogens; Injections, Intraperitoneal; Male; Microdialysis; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa | 2008 |
Effect of kappa-opioid receptor agonists U69593, U50488H, spiradoline and salvinorin A on cocaine-induced drug-seeking in rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Behavior, Addictive; Benzeneacetamides; Cocaine; Diterpenes, Clerodane; Male; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Self Administration | 2009 |
Repeated exposure to the κ-opioid receptor agonist salvinorin A modulates extracellular signal-regulated kinase and reward sensitivity.
Topics: Animals; Cocaine; Cyclic AMP Response Element-Binding Protein; Diterpenes, Clerodane; Drug Interactions; Extracellular Signal-Regulated MAP Kinases; Male; Naltrexone; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reward; Self Stimulation; Signal Transduction; Time Factors | 2011 |
Effects of peripherally restricted κ opioid receptor agonists on pain-related stimulation and depression of behavior in rats.
Topics: Animals; Behavior, Animal; Cocaine; Diterpenes, Clerodane; Flupenthixol; Ketoprofen; Male; Oligopeptides; Pain; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Self Stimulation | 2012 |
A single injection of a novel κ opioid receptor agonist salvinorin A attenuates the expression of cocaine-induced behavioral sensitization in rats.
Topics: Animals; Avoidance Learning; Central Nervous System Sensitization; Cocaine; Conditioning, Psychological; Diterpenes, Clerodane; Immobility Response, Tonic; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Stereotyped Behavior | 2012 |
The 2-methoxy methyl analogue of salvinorin A attenuates cocaine-induced drug seeking and sucrose reinforcements in rats.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Depression; Diterpenes, Clerodane; Drug-Seeking Behavior; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Sucrose; Swimming | 2013 |
Assessment of the kappa opioid agonist, salvinorin A, as a punisher of drug self-administration in monkeys.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Choice Behavior; Cocaine; Conditioning, Operant; Diterpenes, Clerodane; Macaca mulatta; Male; Piperidines; Punishment; Receptors, Opioid, kappa; Remifentanil; Self Administration | 2014 |
Relative Timing Between Kappa Opioid Receptor Activation and Cocaine Determines the Impact on Reward and Dopamine Release.
Topics: Affect; Animals; Cocaine; Diterpenes, Clerodane; Dopamine; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reward; Self Stimulation; Time Factors; Ventral Tegmental Area | 2016 |
Kappa Opioid Receptor Agonist Mesyl Sal B Attenuates Behavioral Sensitization to Cocaine with Fewer Aversive Side-Effects than Salvinorin A in Rodents.
Topics: Animals; Anxiety; Behavior, Animal; Cocaine; Cocaine-Related Disorders; Diterpenes; Diterpenes, Clerodane; Learning; Male; Mesylates; Mice; Motor Activity; Nociception; Pain; Rats; Receptors, Opioid, kappa; Recognition, Psychology | 2018 |
Kappa opioid agonists reduce oxycodone self-administration in male rhesus monkeys.
Topics: Analgesics, Opioid; Animals; Behavior, Addictive; Cocaine; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Macaca mulatta; Male; Morphinans; Naltrexone; Narcotic Antagonists; Oxycodone; Receptors, Opioid, kappa; Reinforcement, Psychology; Self Administration; Spiro Compounds | 2020 |
The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors.
Topics: Animals; Anxiety; Cocaine; HEK293 Cells; Humans; Locomotion; Mice; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Reward | 2023 |