Page last updated: 2024-09-03

salvinorin a and 9-(benzoyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2h-naphtho(2,1-c)pyran-7-carboxylic acid methyl ester

salvinorin a has been researched along with 9-(benzoyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2h-naphtho(2,1-c)pyran-7-carboxylic acid methyl ester in 11 studies

Compound Research Comparison

Studies (salvinorin a)	Trials (salvinorin a)	Recent Studies (post-2010) (salvinorin a)	Studies (9-(benzoyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2h-naphtho(2,1-c)pyran-7-carboxylic acid methyl ester)	Trials (9-(benzoyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2h-naphtho(2,1-c)pyran-7-carboxylic acid methyl ester)	Recent Studies (post-2010) (9-(benzoyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2h-naphtho(2,1-c)pyran-7-carboxylic acid methyl ester)
247	7	128	20	0	12

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (54.55)	29.6817
2010's	5 (45.45)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Butelman, ER; Byrd, N; Cobb, H; Dersch, CM; Harding, WW; Prisinzano, TE; Rothman, RB; Tidgewell, K	1
Cobb, H; Dersch, CM; Deschamps, JR; Harding, WW; Kannan, P; Lozama, A; Parrish, D; Prisinzano, TE; Rothman, RB; Shah, K; Tidgewell, K	1
Bohn, LM; Dersch, CM; Groer, CE; Harding, WW; Hiemstra, J; Lozama, A; Marquam, A; Partilla, JS; Prisinzano, TE; Rothman, RB; Schmidt, M; Tidgewell, K	1
Fujii, H; Hirayama, S; Hirono, S; Iwai, T; Kuroda, N; Nagase, H; Wada, N; Yamaotsu, N	1
Biscaia, M; Crowley, RS; Filizola, M; Groer, CE; Kivell, BM; Paton, K; Prisinzano, TE; Provasi, D; Riley, AP; Schneider, S; Sherwood, AM; Shivaperumal, N	1
Holden, KG; Marquam, A; Navarro, H; Prisinzano, TE; Rothman, RB; Tidgewell, K	1
Butelman, ER; Kreek, MJ; Prisinzano, TE; Rus, S; Simpson, DS; Wolf, A	1
Benaderet, TS; Bishop-Mathis, K; Dersch, CM; Partilla, JS; Prisinzano, TE; Rothman, RB; Simpson, DS; Wang, X; Xu, H	1
Armstead, WM; Ji, F; Liu, R; Ma, N; Riley, J; Wang, Z	1
Prisinzano, TE	1
Bartuzi, D; Kaczor, AA; Matosiuk, D	1

Reviews

1 review(s) available for salvinorin a and 9-(benzoyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2h-naphtho(2,1-c)pyran-7-carboxylic acid methyl ester

Article	Year
Neoclerodanes as atypical opioid receptor ligands. Journal of medicinal chemistry, 2013, May-09, Volume: 56, Issue:9 Topics: Animals; Diterpenes; Diterpenes, Clerodane; Drug Discovery; Furans; Humans; Ligands; Pyrones; Receptors, Opioid	2013

Other Studies

10 other study(ies) available for salvinorin a and 9-(benzoyloxy)-2-(3-furanyl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2h-naphtho(2,1-c)pyran-7-carboxylic acid methyl ester

Article	Year
Neoclerodane diterpenes as a novel scaffold for mu opioid receptor ligands. Journal of medicinal chemistry, 2005, Jul-28, Volume: 48, Issue:15 Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Diterpenes; Diterpenes, Clerodane; Furans; Humans; Ligands; Pyrones; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Salvia; Stereoisomerism; Structure-Activity Relationship	2005
Synthesis of salvinorin A analogues as opioid receptor probes. Journal of natural products, 2006, Volume: 69, Issue:6 Topics: Crystallography, X-Ray; Diterpenes; Diterpenes, Clerodane; Molecular Conformation; Molecular Structure; Plants, Medicinal; Receptors, Opioid; Salvia; Structure-Activity Relationship	2006
Herkinorin analogues with differential beta-arrestin-2 interactions. Journal of medicinal chemistry, 2008, Apr-24, Volume: 51, Issue:8 Topics: Arrestins; beta-Arrestin 2; beta-Arrestins; Cell Line; Diterpenes; Diterpenes, Clerodane; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Radioligand Assay; Receptors, Opioid, kappa; Receptors, Opioid, mu	2008
Synthesis of a novel universal opioid receptor agonist with the 1,3,5-trioxazatriquinane skeleton and its pharmacologies. Bioorganic & medicinal chemistry letters, 2014, Oct-15, Volume: 24, Issue:20 Topics: Animals; Dose-Response Relationship, Drug; Guinea Pigs; Heterocyclic Compounds, 4 or More Rings; Humans; Mice; Molecular Conformation; Receptors, Opioid, kappa; Structure-Activity Relationship	2014
Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Identification of a Potent and Centrally Acting μ Opioid Analgesic with Reduced Abuse Liability. Journal of medicinal chemistry, 2016, 12-22, Volume: 59, Issue:24 Topics: Analgesics, Opioid; Animals; Cells, Cultured; CHO Cells; Cricetulus; Diterpenes; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Male; Molecular Structure; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Salvia; Structure-Activity Relationship	2016
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: exploration of the 1-position. Bioorganic & medicinal chemistry letters, 2007, Nov-15, Volume: 17, Issue:22 Topics: Binding, Competitive; Diterpenes; Diterpenes, Clerodane; Drug Evaluation, Preclinical; Furans; Humans; Molecular Structure; Pyrones; Receptors, Opioid, mu; Recombinant Proteins; Salvia; Structure-Activity Relationship	2007
The effects of herkinorin, the first mu-selective ligand from a salvinorin A-derived scaffold, in a neuroendocrine biomarker assay in nonhuman primates. The Journal of pharmacology and experimental therapeutics, 2008, Volume: 327, Issue:1 Topics: Animals; Biomarkers; Diterpenes, Clerodane; Dose-Response Relationship, Drug; Female; Furans; Loperamide; Macaca mulatta; Male; Naltrexone; Prolactin; Pyrones; Receptors, Opioid, mu	2008
Differential effects of opioid agonists on G protein expression in CHO cells expressing cloned human opioid receptors. Brain research bulletin, 2008, Sep-05, Volume: 77, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Benzamides; Blotting, Western; CHO Cells; Cricetinae; Cricetulus; Diterpenes, Clerodane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Etorphine; Female; Furans; Gene Expression; GTP-Binding Protein alpha Subunits, G12-G13; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Morphine; Oligopeptides; Piperazines; Pyrones; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	2008
Herkinorin dilates cerebral vessels via kappa opioid receptor and cyclic adenosine monophosphate (cAMP) in a piglet model. Brain research, 2013, Jan-15, Volume: 1490 Topics: Animals; Animals, Newborn; Binding Sites; Cell Line; Cerebral Arteries; Cerebrovascular Circulation; Cyclic AMP; Diterpenes, Clerodane; Female; Furans; Humans; Male; Models, Molecular; Psychotropic Drugs; Pyrones; Receptors, Opioid, kappa; Receptors, Opioid, mu; Swine; Vasodilator Agents	2013
Activation and Allosteric Modulation of Human μ Opioid Receptor in Molecular Dynamics. Journal of chemical information and modeling, 2015, Nov-23, Volume: 55, Issue:11 Topics: Allosteric Regulation; Allosteric Site; Diterpenes, Clerodane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Furans; Humans; Ligands; Molecular Docking Simulation; Molecular Dynamics Simulation; Morphine; Pyrones; Receptors, Opioid, mu; Salvia	2015