Page last updated: 2024-08-24

salvin and carnosol

salvin has been researched along with carnosol in 76 studies

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (7.89)18.2507
2000's19 (25.00)29.6817
2010's44 (57.89)24.3611
2020's7 (9.21)2.80

Authors

AuthorsStudies
Korant, BD; Paris, A; Pukl, M; Renko, M; Strukelj, B; Turk, V; Umek, A1
Hosny, M; Johnson, HA; Rosazza, JP; Ueltschy, AK1
Jain, KS; Kathiravan, MK; Shishoo, CJ; Somani, RS1
Fischedick, JT; Johnson, DA; Johnson, JA; Standiford, M1
Connelly, M; Fatima, I; Gautam, LN; González, MA; Ling, T; Miranda-Carboni, G; Rivas, F; Tran, M; Wood, RK1
Atanasov, AG; Kamal, MA; Khan, H; Nabavi, SM; Pervaiz, A; Rengasamy, KRR1
Cai, N; Han, S; Han, X; Li, X; Malwal, SR; Oldfield, E; Xia, Y; Yu, Z; Zhang, Y1
Aeschbach, R; Aruoma, OI; Halliwell, B; Löligers, J1
Schwarz, K; Ternes, W1
Geoffroy, M; Lambelet, P; Richert, P1
Aeschbach, R; Aruoma, OI; Butler, J; Halliwell, B; Khan, A; Mahmood, N; Munoz, A; Murcia, A; Rossi, R; Spencer, JP1
Alegre, L; Munné-Bosch, S; Schwarz, K1
Fiander, H; Schneider, H1
Andrés, LS; Luis, JG; Marrero, JG1
Escuder, B; Faini, F; Labbé, C; Lissi, E; Torres, R1
Cavero, S; Hawthorne, SB; Ibañez, E; Kubátová, A; Reglero, G; Señoráns, FJ1
Benavente-García, O; Castillo, J; del Baño, MJ; del Río, JA; Gerard, D; Lorente, J; Ortuño, A; Quirin, KW1
Kapsokefalou, M; Matsingou, TC; Petrakis, N; Salifoglou, A1
Gibbons, S; Kaatz, GW; Oluwatuyi, M1
Padfield, PJ; Thompson, DG; Visanji, JM1
Albert, K; Exarchou, V; Gerothanassis, IP; Krucker, M; van Beek, TA; Vervoort, J1
Moreno, S; Romano, CS; Scheyer, T; Vojnov, AA1
Acevedo, C; Alcaraz, M; Benavente-García, O; Castillo, J; Del Baño, MJ; Lorente, J; Martín-Gil, R1
Abdel-Tawab, M; Bock, A; Dingermann, T; Meindl, N; Paulke, A; Rau, O; Schubert-Zsilavecz, M; Wurglics, M; Zitzkowski, J1
Cuppett, SL; Wijeratne, SS1
Hatano, T; Horiuchi, K; Kuroda, T; Shiota, S; Tsuchiya, T; Yoshida, T1
Inukai, Y; Itoh, K; Izumi, M; Kitajima, C; Kosaka, K; Nakayama, N; Satoh, T; Shimojo, Y; Shirasawa, T; Tsutsumi, Y; Yokoi, T1
Greiner, C; Hörnig, C; Poeckel, D; Rau, O; Schubert-Zsilavecz, M; Steinhilber, D; Tausch, L; Verhoff, M; Werz, O1
Kosaka, K; Satoh, T; Tabuchi, T; Takahashi, T; Takikawa, Y; Tamaki, Y1
Kosaka, K; Satoh, T; Tabuchi, T; Takahashi, T; Tamaki, Y1
Kurabe, J; Ohkanda, T; Tada, M1
Bernardes, WA; Crotti, AE; Cunha, WR; Filho, AA; Groppo, M; Lucarini, R; Martins, CH; Pauletti, PM; Silva, ML; Souza, MG; Tozatti, MG1
Fliser, E; Knez, Z; Lokar, L; Novak, Z; Sinkovic, A; Skerget, M; Suran, D1
Lin, CY; Tsai, CW; Wang, YJ1
García-Caballero, M; López-Jiménez, A; Medina, MÁ; Quesada, AR1
Kayashima, T; Matsubara, K1
Cheung, S; Hasman, D; Tai, J; Wu, M1
Bauer, J; Koeberle, A; Kuehnl, S; Northoff, H; Rollinger, JM; Scherer, O; Stuppner, H; Werz, O1
Armstrong, DW; Dodbiba, E; Lang, JC; Rangarajan, R; Smuts, JP; Zhang, Y1
Jordán, MJ; Lax, V; Lorán, S; Rota, MC; Sotomayor, JA1
Chae, IG; Chun, KS; Im, NK; Jung, YT; Lee, IS; Lee, J; Yu, MH1
Chen, WY; Chuang, LT; Lien, TJ; Liing, YR; Tsai, PJ; Tsai, TH1
Espín, JC; Flanagan, J; Fromentin, E; García Villalba, R; García-Conesa, MT; Larrosa, M; Roller, M; Romo Vaquero, M; Tomás-Barberán, FA; Yáñez-Gascón, MJ1
Chen, G; Ma, G; Tang, D; Zhang, L1
Bañón, S; Jordán, MJ; Ortuño, J; Serrano, R1
Cifuentes, A; Ferragut, JA; García-Cañas, V; Ibáñez, C; Micol, V; Simó, C; Valdés, A1
Arredondo, S; Calderón, D; Faini, F; Labbé, C; Molina, J1
Apers, S; Charalambous, Z; Exarchou, V; Gekas, V; Goulas, V; Kanetis, L; Pieters, L1
Bily, AC; Birtić, S; Dussort, P; Pierre, FX; Roller, M1
Carvalho, AC; Gomes, AC; Lima, CF; Pereira-Wilson, C1
Dmitrović, S; Filipović, B; Kračun-Kolarević, M; Mišić, D; Perić, M; Simonović, A; Todorović, S1
Chang, SW; Lin, CY; Tsai, CW; Wang, YJ; Wu, CR; Wu, JJ1
Butassi, E; Pertino, MW; Schmeda-Hirschmann, G; Theoduloz, C; Zacchino, S1
Johnson, JJ; Petiwala, SM1
Bañón, S; Ortuño, J; Serrano, R1
Bily, A; Chemat, F; Danguien, M; Fabiano-Tixier, AS; Jacotet-Navarro, M; Rombaut, N1
Fuchino, H; Iida, O; Itoh, Y; Kagawa, M; Kawahara, H; Kawahara, N; Kumagai, A; Kuroi, A; Nagaoka, Y; Sugimura, K; Takemori, H; Watanabe, H; Yamahara, M1
González-Vallinas, M; Ramírez de Molina, A; Reglero, G1
de Oliveira, MR1
da Conceição, EC; de Oliveira, AE; Leles, MI; Oliveira, Gde A1
Bifulco, G; Bisio, A; Cantone, V; Chini, MG; Koeberle, A; Maione, F; Mascolo, N; Pace, S; Pieretti, S; Romussi, G; Werz, O1
Balcke, GU; Božić, D; Brandt, W; Ferrer, A; Henning, A; Kanellis, AK; Lohse, S; Manzano, D; Marillonnet, S; Papaefthimiou, D; Porzel, A; Rothe, K; Scheler, U; Tissier, A1
Artemenko, KA; Bergquist, J; Cifuentes, A; García-Cañas, V; Simó, C; Valdés, A1
Cifuentes, A; García-Cañas, V; Herrero, M; Ibáñez, E; Sánchez-Camargo, AD1
Grace, MH; Lila, MA; Qiang, Y; Sang, S1
Lau, AJ; Seow, CL1
Jacobsen, C; Qiu, X; Sørensen, AM1
Karadas, O; Mese, G; Ozcivici, E1
Li, P; Li, Y; Lin, H; Liu, A; Liu, Z; Xiao, W; Yuan, B; Zhang, S1
Castillo-Sánchez, J; Mira-Sánchez, MD; Morillas-Ruiz, JM1
Bao, TQ; Li, P; Li, Y; Qu, C; Yang, H; Zheng, ZG1
Destandau, E; Lefebvre, T; Lesellier, E1
Johnson, JJ; Nauman, MC; Tocmo, R; Veenstra, JP; Vemu, B1
Asano, T; Fujishiro, M; Hasei, S; Itoga, S; Kushiyama, A; Matsunaga, Y; Nakatsu, Y; Nonaka, Y; Ohata, Y; Sakoda, H; Yamamotoya, T1
Baiamonte, I; Cervelli, C; De Benedetti, L; Lupotto, E; Marchioni, I; Nardo, N; Raffo, A1
Hrebień-Filisińska, AM; Tokarczyk, G1

Reviews

7 review(s) available for salvin and carnosol

ArticleYear
The biology and chemistry of hyperlipidemia.
    Bioorganic & medicinal chemistry, 2007, Jul-15, Volume: 15, Issue:14

    Topics: Animals; Atherosclerosis; Biochemical Phenomena; Biochemistry; Disease Progression; Drug Design; Humans; Hyperlipidemias; Lipoproteins

2007
Plant-derived mPGES-1 inhibitors or suppressors: A new emerging trend in the search for small molecules to combat inflammation.
    European journal of medicinal chemistry, 2018, Jun-10, Volume: 153

    Topics: Animals; Anti-Inflammatory Agents; Biological Products; Drug Discovery; Enzyme Inhibitors; Humans; Inflammation; Plants, Medicinal; Prostaglandin-E Synthases

2018
LC-NMR coupling technology: recent advancements and applications in natural products analysis.
    Magnetic resonance in chemistry : MRC, 2005, Volume: 43, Issue:9

    Topics: Abietanes; Biological Products; Chromatography, Liquid; Cinnamates; Depsides; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microchemistry; Phenanthrenes; Plant Extracts; Reproducibility of Results; Rosmarinic Acid; Sensitivity and Specificity

2005
Diterpenes from rosemary (Rosmarinus officinalis): Defining their potential for anti-cancer activity.
    Cancer letters, 2015, Oct-28, Volume: 367, Issue:2

    Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Diterpenes; Humans; Neoplasms; Phytotherapy; Plant Extracts; Plants, Medicinal; Rosmarinus; Signal Transduction

2015
Rosemary (Rosmarinus officinalis L.) Extract as a Potential Complementary Agent in Anticancer Therapy.
    Nutrition and cancer, 2015, Volume: 67, Issue:8

    Topics: Abietanes; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Breast Neoplasms; Cinnamates; Depsides; Drug Interactions; Europe; Humans; Neoplasms; Phytotherapy; Plant Extracts; Rosmarinic Acid; Rosmarinus; Triterpenes; United States; United States Food and Drug Administration; Ursolic Acid

2015
The Dietary Components Carnosic Acid and Carnosol as Neuroprotective Agents: a Mechanistic View.
    Molecular neurobiology, 2016, Volume: 53, Issue:9

    Topics: Abietanes; Animals; Diet; Humans; Neuroglia; Neurons; Neuroprotective Agents

2016
Antidiabetic Effects and Mechanisms of Rosemary (
    The American journal of Chinese medicine, 2020, Volume: 48, Issue:6

    Topics: Abietanes; Animals; Anti-Inflammatory Agents; Antioxidants; Cinnamates; Depsides; Diabetes Mellitus; Glucose; Humans; Lipid Metabolism; Phenols; Phytotherapy; Plant Extracts; Rosmarinic Acid; Rosmarinus

2020

Other Studies

69 other study(ies) available for salvin and carnosol

ArticleYear
Inhibitory effect of carnosic acid on HIV-1 protease in cell-free assays [corrected].
    Journal of natural products, 1993, Volume: 56, Issue:8

    Topics: Abietanes; Animals; Cathepsin D; Cattle; Cell-Free System; HIV Protease Inhibitors; HIV-1; Humans; Pepsin A; Phenanthrenes; Plants, Medicinal; Virus Replication

1993
Oxidation, reduction, and methylation of carnosic acid by Nocardia.
    Journal of natural products, 2002, Volume: 65, Issue:9

    Topics: Abietanes; Antioxidants; Biphenyl Compounds; Cyclization; Diterpenes; Free Radical Scavengers; Mass Spectrometry; Methylation; Molecular Structure; Nocardia; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Picrates; Plant Extracts; Rosmarinus; Structure-Activity Relationship

2002
Structure activity relationship of phenolic diterpenes from Salvia officinalis as activators of the nuclear factor E2-related factor 2 pathway.
    Bioorganic & medicinal chemistry, 2013, May-01, Volume: 21, Issue:9

    Topics: Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Diterpenes; Dose-Response Relationship, Drug; Hydrogen Peroxide; Mice; Molecular Structure; Neurons; NF-E2-Related Factor 2; Oxidative Stress; Phenols; Plant Extracts; Salvia officinalis; Structure-Activity Relationship

2013
(+)-Dehydroabietylamine derivatives target triple-negative breast cancer.
    European journal of medicinal chemistry, 2015, Sep-18, Volume: 102

    Topics: Abietanes; Antineoplastic Agents, Phytogenic; Apoptosis; Biological Products; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Female; Humans; MCF-7 Cells; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Triple Negative Breast Neoplasms

2015
Farnesyl Pyrophosphate Synthase as a Target for Drug Development: Discovery of Natural-Product-Derived Inhibitors and Their Activity in Pancreatic Cancer Cells.
    Journal of medicinal chemistry, 2019, 12-12, Volume: 62, Issue:23

    Topics: Antineoplastic Agents; Binding Sites; Biological Products; Cell Line, Tumor; Cell Survival; Computational Biology; Geranyltranstransferase; Humans; Pancreatic Neoplasms; Protein Conformation

2019
Antioxidant and pro-oxidant properties of active rosemary constituents: carnosol and carnosic acid.
    Xenobiotica; the fate of foreign compounds in biological systems, 1992, Volume: 22, Issue:2

    Topics: Abietanes; Antioxidants; Bleomycin; Carnosine; Deoxyribose; Diterpenes; DNA Damage; Free Radical Scavengers; Free Radicals; Horseradish Peroxidase; Hydrogen Peroxide; Hypochlorous Acid; Lipid Peroxidation; Magnoliopsida; Oxidants; Phenanthrenes; Plant Extracts; Superoxides

1992
Antioxidative constituents of Rosmarinus officinalis and Salvia officinalis. II. Isolation of carnosic acid and formation of other phenolic diterpenes.
    Zeitschrift fur Lebensmittel-Untersuchung und -Forschung, 1992, Volume: 195, Issue:2

    Topics: Abietanes; Antioxidants; Carnosine; Chromatography, High Pressure Liquid; Diterpenes; Magnetic Resonance Spectroscopy; Magnoliopsida; Mass Spectrometry; Oxidation-Reduction; Phenanthrenes; Plant Extracts; Spectrophotometry, Infrared

1992
Radical intermediates and antioxidants: an ESR study of radicals formed on carnosic acid in the presence of oxidized lipids.
    Free radical research, 1994, Volume: 21, Issue:4

    Topics: Abietanes; Antioxidants; Diterpenes; Electron Spin Resonance Spectroscopy; Free Radicals; Lipids; Oleic Acids; Phenanthrenes; Plant Extracts; Spices

1994
An evaluation of the antioxidant and antiviral action of extracts of rosemary and Provençal herbs.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1996, Volume: 34, Issue:5

    Topics: Abietanes; Antioxidants; Antiviral Agents; Biological Assay; Diterpenes; DNA Damage; Evaluation Studies as Topic; HIV-1; Humans; Lipid Peroxidation; Liposomes; Lymphoma, T-Cell; Magnoliopsida; Phenanthrenes; Plant Extracts; Spices; T-Lymphocytes; Tumor Cells, Cultured

1996
Response of abietane diterpenes to stress in Rosmarinus officinalis L.: new insights into the function of diterpenes in plants.
    Free radical research, 1999, Volume: 31 Suppl

    Topics: Abietanes; Antioxidants; Climate; Diterpenes; Lamiaceae; Mediterranean Region; Oxidative Stress; Phenanthrenes; Plant Extracts

1999
Dietary ortho phenols that induce glutathione S-transferase and increase the resistance of cells to hydrogen peroxide are potential cancer chemopreventives that act by two mechanisms: the alleviation of oxidative stress and the detoxification of mutagenic
    Cancer letters, 2000, Aug-11, Volume: 156, Issue:2

    Topics: Abietanes; Anticarcinogenic Agents; Antioxidants; Diet; Diterpenes; Enzyme Induction; Flavonoids; Flavonols; Glutathione Transferase; Humans; Hydrogen Peroxide; Inactivation, Metabolic; Inhibitory Concentration 50; Isomerism; Mutagens; Oxidative Stress; Phenanthrenes; Phenols; Plant Extracts; Structure-Activity Relationship; Tumor Cells, Cultured

2000
Semisynthesis of rosmanol and its derivatives. Easy access to abietatriene diterpenes isolated from the genus Salvia with biological activities.
    Journal of natural products, 2002, Volume: 65, Issue:7

    Topics: Abietanes; Catalysis; Diterpenes; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Phenanthrenes; Plant Extracts; Plant Leaves; Plants, Medicinal; Salvia

2002
Antioxidant capacity of abietanes from Sphacele salviae.
    Natural product letters, 2002, Volume: 16, Issue:4

    Topics: Abietanes; Antioxidants; Biphenyl Compounds; Butylated Hydroxytoluene; Chile; Diterpenes; Dose-Response Relationship, Drug; Lamiaceae; Medicine, Traditional; Phenanthrenes; Picrates; Plant Extracts; Plant Leaves; Plants, Medicinal; Structure-Activity Relationship; Time Factors; Vitamin E

2002
Subcritical water extraction of antioxidant compounds from rosemary plants.
    Journal of agricultural and food chemistry, 2003, Jan-15, Volume: 51, Issue:2

    Topics: Abietanes; Antioxidants; Chromatography, High Pressure Liquid; Chromatography, Liquid; Diterpenes; Flavonoids; Mass Spectrometry; Molecular Structure; Phenanthrenes; Plant Extracts; Plant Leaves; Rosmarinus; Temperature; Water

2003
Phenolic diterpenes, flavones, and rosmarinic acid distribution during the development of leaves, flowers, stems, and roots of Rosmarinus officinalis. Antioxidant activity.
    Journal of agricultural and food chemistry, 2003, Jul-16, Volume: 51, Issue:15

    Topics: Abietanes; Antioxidants; Cinnamates; Depsides; Diterpenes; Flavonoids; Flowers; Phenanthrenes; Phenols; Plant Extracts; Plant Leaves; Plant Roots; Plant Stems; Polymers; Rosmarinic Acid; Rosmarinus

2003
Antioxidant activity of organic extracts from aqueous infusions of sage.
    Journal of agricultural and food chemistry, 2003, Nov-05, Volume: 51, Issue:23

    Topics: Abietanes; Antioxidants; Caffeic Acids; Chromatography, High Pressure Liquid; Diterpenes; Flavonoids; Phenanthrenes; Phenols; Plant Extracts; Polyphenols; Salvia officinalis; Water

2003
Antibacterial and resistance modifying activity of Rosmarinus officinalis.
    Phytochemistry, 2004, Volume: 65, Issue:24

    Topics: Abietanes; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Phenanthrenes; Plant Extracts; Rosmarinus; Staphylococcus aureus

2004
Induction of G2/M phase cell cycle arrest by carnosol and carnosic acid is associated with alteration of cyclin A and cyclin B1 levels.
    Cancer letters, 2006, Jun-08, Volume: 237, Issue:1

    Topics: Abietanes; Antineoplastic Agents; Antioxidants; Caco-2 Cells; Cell Division; Cell Proliferation; Cyclin A; Cyclin B; Cyclin B1; Down-Regulation; G2 Phase; Humans; Inhibitory Concentration 50; Phenanthrenes; Plant Extracts

2006
Antioxidant and antimicrobial activities of rosemary extracts linked to their polyphenol composition.
    Free radical research, 2006, Volume: 40, Issue:2

    Topics: Abietanes; Anti-Infective Agents; Antioxidants; Bacteria; Biphenyl Compounds; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Flavonoids; Free Radicals; Indicators and Reagents; Phenanthrenes; Phenols; Picrates; Plant Extracts; Polyphenols; Rosmarinic Acid; Rosmarinus; Saccharomyces cerevisiae

2006
Radioprotective-antimutagenic effects of rosemary phenolics against chromosomal damage induced in human lymphocytes by gamma-rays.
    Journal of agricultural and food chemistry, 2006, Mar-22, Volume: 54, Issue:6

    Topics: Abietanes; Antimutagenic Agents; Cell Nucleus; Cinnamates; Depsides; DNA Damage; Gamma Rays; Lymphocytes; Phenanthrenes; Plant Extracts; Radiation-Protective Agents; Rosmarinic Acid; Rosmarinus

2006
Carnosic acid and carnosol, phenolic diterpene compounds of the labiate herbs rosemary and sage, are activators of the human peroxisome proliferator-activated receptor gamma.
    Planta medica, 2006, Volume: 72, Issue:10

    Topics: Abietanes; Animals; Chlorocebus aethiops; COS Cells; Genes, Reporter; Humans; Phenanthrenes; Plant Extracts; PPAR gamma; Recombinant Fusion Proteins; Rosmarinus; Salvia officinalis

2006
Potential of rosemary (Rosemarinus officinalis L.) diterpenes in preventing lipid hydroperoxide-mediated oxidative stress in Caco-2 cells.
    Journal of agricultural and food chemistry, 2007, Feb-21, Volume: 55, Issue:4

    Topics: Abietanes; Antioxidants; Caco-2 Cells; Humans; Lipid Peroxides; Oxidative Stress; Phenanthrenes; Plant Extracts; Rosmarinus

2007
Potentiation of antimicrobial activity of aminoglycosides by carnosol from Salvia officinalis.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:2

    Topics: Abietanes; Aminoglycosides; Anti-Bacterial Agents; Drug Synergism; Enterococcus faecalis; Enterococcus faecium; Methicillin Resistance; Microbial Sensitivity Tests; Phenanthrenes; Plant Extracts; Plant Leaves; Pseudomonas aeruginosa; Salvia officinalis; Serratia marcescens; Staphylococcus aureus; Vancomycin Resistance

2007
Carnosic acid protects neuronal HT22 Cells through activation of the antioxidant-responsive element in free carboxylic acid- and catechol hydroxyl moieties-dependent manners.
    Neuroscience letters, 2008, Apr-04, Volume: 434, Issue:3

    Topics: Abietanes; Adaptor Proteins, Signal Transducing; Animals; Antioxidants; Carboxylic Acids; Catechols; Cell Line; Cytoprotection; Cytoskeletal Proteins; Drug Evaluation, Preclinical; Esterases; Gene Expression Regulation; Glutathione; Hydroxyl Radical; Kelch-Like ECH-Associated Protein 1; Membrane Lipids; Mice; Molecular Structure; Neurons; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Phenanthrenes; Plant Extracts; Response Elements; Steroids

2008
Carnosic acid and carnosol potently inhibit human 5-lipoxygenase and suppress pro-inflammatory responses of stimulated human polymorphonuclear leukocytes.
    Biochemical pharmacology, 2008, Jul-01, Volume: 76, Issue:1

    Topics: Abietanes; Calcium; Homeostasis; Humans; Lipoxygenase Inhibitors; Neutrophils; Plant Extracts; Reactive Oxygen Species

2008
Carnosic acid and carnosol inhibit adipocyte differentiation in mouse 3T3-L1 cells through induction of phase2 enzymes and activation of glutathione metabolism.
    Biochemical and biophysical research communications, 2009, May-08, Volume: 382, Issue:3

    Topics: 3T3-L1 Cells; Abietanes; Active Transport, Cell Nucleus; Adipocytes; Adipogenesis; Animals; Enzymes; G2 Phase; Gene Expression; Glutathione; Mice; NF-E2-Related Factor 2; Oligonucleotide Array Sequence Analysis; Plant Extracts; Response Elements

2009
Activated glutathione metabolism participates in protective effects of carnosic acid against oxidative stress in neuronal HT22 cells.
    Planta medica, 2010, Volume: 76, Issue:7

    Topics: Abietanes; Animals; Antioxidants; Cell Line; Drug Evaluation, Preclinical; Gene Expression Profiling; Glutathione; Mice; Neuroprotective Agents; Oligonucleotide Array Sequence Analysis; Plant Extracts; Rosmarinus

2010
Syntheses of carnosic acid and carnosol, anti-oxidants in Rosemary, from pisiferic acid, the major constituent of Sawara.
    Chemical & pharmaceutical bulletin, 2010, Volume: 58, Issue:1

    Topics: Abietanes; Anti-Bacterial Agents; Antioxidants; Chamaecyparis; Diterpenes; Plant Extracts; Propionibacterium acnes; Rosmarinus; Staphylococcus aureus

2010
Antimicrobial activity of Rosmarinus officinalis against oral pathogens: relevance of carnosic acid and carnosol.
    Chemistry & biodiversity, 2010, Volume: 7, Issue:7

    Topics: Abietanes; Anti-Infective Agents; Dental Caries; Enterococcus faecalis; Microbial Sensitivity Tests; Plant Extracts; Plant Leaves; Plant Stems; Rosmarinus; Streptococcus

2010
Rosemary extracts improve flow-mediated dilatation of the brachial artery and plasma PAI-1 activity in healthy young volunteers.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:3

    Topics: Abietanes; Administration, Oral; Adult; Brachial Artery; Cinnamates; Depsides; Endothelium, Vascular; Female; Humans; Male; Plant Extracts; Plasminogen Activator Inhibitor 1; Prospective Studies; Rosmarinic Acid; Rosmarinus; Ultrasonography; Vasodilation; Vasodilator Agents

2011
Carnosic acid induces the NAD(P)H: quinone oxidoreductase 1 expression in rat clone 9 cells through the p38/nuclear factor erythroid-2 related factor 2 pathway.
    The Journal of nutrition, 2011, Volume: 141, Issue:12

    Topics: Abietanes; Animals; Anticarcinogenic Agents; Antioxidants; Blotting, Western; Cell Nucleus; Cells, Cultured; Dose-Response Relationship, Drug; Gene Silencing; Liver; Luciferases; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Extracts; Plasmids; Rats; Response Elements; RNA, Messenger; Signal Transduction; Transcription, Genetic; Transfection; Up-Regulation

2011
Anti-angiogenic properties of carnosol and carnosic acid, two major dietary compounds from rosemary.
    European journal of nutrition, 2013, Volume: 52, Issue:1

    Topics: Abietanes; Angiogenesis Inhibitors; Animals; Antioxidants; Apoptosis; Cattle; Cell Movement; Cells, Cultured; Collagen; Drug Combinations; HL-60 Cells; Human Umbilical Vein Endothelial Cells; Humans; Laminin; Matrix Metalloproteinase 2; Plant Extracts; Plant Leaves; Proteoglycans; Rosmarinus; Vascular Endothelial Growth Factor Receptor-2

2013
Antiangiogenic effect of carnosic acid and carnosol, neuroprotective compounds in rosemary leaves.
    Bioscience, biotechnology, and biochemistry, 2012, Volume: 76, Issue:1

    Topics: Abietanes; Angiogenesis Inhibitors; Animals; Aorta; Human Umbilical Vein Endothelial Cells; Humans; In Vitro Techniques; Male; Neovascularization, Physiologic; Neuroprotective Agents; Plant Extracts; Plant Leaves; Rats; Rats, Wistar; Rosmarinus

2012
Antiproliferation effect of Rosemary (Rosmarinus officinalis) on human ovarian cancer cells in vitro.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2012, Mar-15, Volume: 19, Issue:5

    Topics: Abietanes; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cinnamates; Cisplatin; Depsides; Drug Therapy, Combination; Female; Gene Expression Regulation, Neoplastic; Humans; Ovarian Neoplasms; Plant Extracts; Plant Leaves; Rosmarinic Acid; Rosmarinus

2012
Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 342, Issue:1

    Topics: Abietanes; Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Humans; Intramolecular Oxidoreductases; Microsomes; Plant Extracts; Plant Leaves; Prostaglandin-E Synthases; Prostaglandins; Salvia officinalis

2012
Degradation study of carnosic acid, carnosol, rosmarinic acid, and rosemary extract (Rosmarinus officinalis L.) assessed using HPLC.
    Journal of agricultural and food chemistry, 2012, Sep-12, Volume: 60, Issue:36

    Topics: Abietanes; Antioxidants; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Kinetics; Plant Extracts; Rosmarinic Acid; Rosmarinus; Temperature

2012
Relevance of carnosic acid, carnosol, and rosmarinic acid concentrations in the in vitro antioxidant and antimicrobial activities of Rosmarinus officinalis (L.) methanolic extracts.
    Journal of agricultural and food chemistry, 2012, Sep-26, Volume: 60, Issue:38

    Topics: Abietanes; Anti-Bacterial Agents; Antioxidants; Cinnamates; Depsides; Listeria monocytogenes; Methanol; Plant Extracts; Rosmarinic Acid; Rosmarinus; Staphylococcus aureus

2012
Effect of Rosemarinus officinalis L. on MMP-9, MCP-1 levels, and cell migration in RAW 264.7 and smooth muscle cells.
    Journal of medicinal food, 2012, Volume: 15, Issue:10

    Topics: Abietanes; Animals; Anti-Inflammatory Agents; Atherosclerosis; Blotting, Western; Cell Line; Cell Movement; Chemokine CCL2; Chromatography, High Pressure Liquid; Matrix Metalloproteinase 9; Mice; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Plant Extracts; Rosmarinus; Tumor Necrosis Factor-alpha

2012
Rosmarinus officinalis extract suppresses Propionibacterium acnes-induced inflammatory responses.
    Journal of medicinal food, 2013, Volume: 16, Issue:4

    Topics: Abietanes; Acne Vulgaris; Animals; Anti-Inflammatory Agents; Cinnamates; Cytokines; Depsides; Humans; Inflammation; Inflammation Mediators; Male; Mice; Mice, Inbred ICR; Phytotherapy; Plant Extracts; Propionibacterium acnes; RNA, Messenger; Rosmarinic Acid; Rosmarinus; Signal Transduction

2013
Bioavailability of the major bioactive diterpenoids in a rosemary extract: metabolic profile in the intestine, liver, plasma, and brain of Zucker rats.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:10

    Topics: Abietanes; Animals; Biological Availability; Brain; Chromatography, Liquid; Diterpenes; Female; Glucuronides; Intestinal Mucosa; Intestines; Liver; Metabolome; Oils, Volatile; Plant Extracts; Rats; Rats, Zucker; Rosmarinus; Tandem Mass Spectrometry

2013
Graphene-epoxy composite electrode fabricated by in situ polycondensation for enhanced amperometric detection in capillary electrophoresis.
    Journal of chromatography. A, 2013, Nov-05, Volume: 1316

    Topics: Abietanes; Electrodes; Electrophoresis, Capillary; Epoxy Resins; Graphite; Models, Chemical; Plant Extracts; Rosmarinus

2013
Shelf life of meat from lambs given essential oil-free rosemary extract containing carnosic acid plus carnosol at 200 or 400 mg kg⁻¹.
    Meat science, 2014, Volume: 96, Issue:4

    Topics: Abietanes; Animal Feed; Animals; Anti-Infective Agents; Antioxidants; Color; Dietary Supplements; Food Microbiology; Food Preservation; Humans; Lipid Peroxidation; Meat; Odorants; Plant Extracts; Rosmarinus; Sheep, Domestic

2014
Comprehensive foodomics study on the mechanisms operating at various molecular levels in cancer cells in response to individual rosemary polyphenols.
    Analytical chemistry, 2014, Oct-07, Volume: 86, Issue:19

    Topics: Abietanes; Antineoplastic Agents, Phytogenic; Biological Transport; Cell Proliferation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glutathione; HT29 Cells; Humans; Inactivation, Metabolic; Metabolomics; Plant Extracts; Polyphenols; Putrescine; Reactive Oxygen Species; Rosmarinus; Signal Transduction; Transcription, Genetic

2014
Variations of carnosic acid and carnosol concentrations in ethanol extracts of wild Lepechinia salviae in Spring (2008-2011).
    Natural product communications, 2014, Volume: 9, Issue:10

    Topics: Abietanes; Antineoplastic Agents; Antioxidants; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Ethanol; Humans; Lamiaceae; Picrates; Plant Extracts; Plant Leaves

2014
HPLC-SPE-NMR characterization of major metabolites in Salvia fruticosa Mill. extract with antifungal potential: relevance of carnosic acid, carnosol, and hispidulin.
    Journal of agricultural and food chemistry, 2015, Jan-21, Volume: 63, Issue:2

    Topics: Abietanes; Antifungal Agents; Chromatography, High Pressure Liquid; Flavones; Fungi; Magnetic Resonance Spectroscopy; Plant Extracts; Salvia

2015
Carnosic acid.
    Phytochemistry, 2015, Volume: 115

    Topics: Abietanes; Animals; Anti-Infective Agents; Antioxidants; Chromatography, High Pressure Liquid; Humans; Mice; Molecular Structure; Plant Leaves; Rats; Rosmarinus; Salvia; Sheep

2015
Redox-dependent induction of antioxidant defenses by phenolic diterpenes confers stress tolerance in normal human skin fibroblasts: Insights on replicative senescence.
    Free radical biology & medicine, 2015, Volume: 83

    Topics: Abietanes; Adult; Antioxidants; Apoptosis; Blotting, Western; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cellular Senescence; Female; Fibroblasts; Humans; Immunoenzyme Techniques; NF-E2-Related Factor 2; Oxidation-Reduction; Oxidative Stress; Plant Extracts; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin

2015
Influence of sodium salicylate on rosmarinic acid, carnosol and carnosic acid accumulation by Salvia officinalis L. shoots grown in vitro.
    Biotechnology letters, 2015, Volume: 37, Issue:8

    Topics: Abietanes; Cinnamates; Culture Media; Depsides; Plant Development; Plant Shoots; Rosmarinic Acid; Salvia officinalis; Sodium Salicylate

2015
Induction of the pi class of glutathione S-transferase by carnosic acid in rat Clone 9 cells via the p38/Nrf2 pathway.
    Food & function, 2015, Volume: 6, Issue:6

    Topics: Abietanes; Active Transport, Cell Nucleus; Animals; Anticarcinogenic Agents; Clone Cells; Electrophoretic Mobility Shift Assay; Enhancer Elements, Genetic; Enzyme Induction; Enzyme Inhibitors; Genes, Reporter; Glutathione S-Transferase pi; Hepatocytes; Imidazoles; Membrane Glycoproteins; NF-E2-Related Factor 2; Pyridines; Rats; Recombinant Proteins; RNA Interference; Rosmarinus; Signal Transduction; Up-Regulation

2015
Synthesis, antiproliferative and antifungal activities of 1,2,3-triazole-substituted carnosic Acid and carnosol derivatives.
    Molecules (Basel, Switzerland), 2015, May-14, Volume: 20, Issue:5

    Topics: Abietanes; Antifungal Agents; Candida albicans; Cell Line, Tumor; Cell Proliferation; Click Chemistry; Cryptococcus neoformans; Fibroblasts; Humans; Microbial Sensitivity Tests; Neoplasms; Plant Extracts; Structure-Activity Relationship; Triazoles

2015
Antioxidant and antimicrobial effects of dietary supplementation with rosemary diterpenes (carnosic acid and carnosol) vs vitamin E on lamb meat packed under protective atmosphere.
    Meat science, 2015, Volume: 110

    Topics: Abietanes; Animals; Anti-Infective Agents; Antioxidants; Bacteria; Color; Dietary Supplements; Female; Food Microbiology; Food Packaging; Food Preservation; Food Storage; Humans; Male; Meat; Muscles; Odorants; Plant Extracts; Rosmarinus; Sheep; Vitamin E

2015
Ultrasound versus microwave as green processes for extraction of rosmarinic, carnosic and ursolic acids from rosemary.
    Ultrasonics sonochemistry, 2015, Volume: 27

    Topics: Abietanes; Chemical Fractionation; Cinnamates; Depsides; Green Chemistry Technology; Microwaves; Rosmarinic Acid; Rosmarinus; Terpenes; Triterpenes; Ultrasonic Waves; Ursolic Acid

2015
Callicarpa longissima extract, carnosol-rich, potently inhibits melanogenesis in B16F10 melanoma cells.
    Journal of natural medicines, 2016, Volume: 70, Issue:1

    Topics: Abietanes; Animals; Callicarpa; Cell Differentiation; Cell Line, Tumor; Chromatography, Liquid; Gene Expression; Humans; Mass Spectrometry; Melanins; Melanoma, Experimental; Mice; Microphthalmia-Associated Transcription Factor; Plant Extracts; Skin Lightening Preparations; Skin Pigmentation

2016
Multiresponse optimization of an extraction procedure of carnosol and rosmarinic and carnosic acids from rosemary.
    Food chemistry, 2016, Nov-15, Volume: 211

    Topics: Abietanes; Antioxidants; Cinnamates; Depsides; Plant Extracts; Powders; Rosmarinic Acid; Rosmarinus

2016
Anti-inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions.
    British journal of pharmacology, 2017, Volume: 174, Issue:11

    Topics: Abietanes; Analgesics; Animals; Anti-Inflammatory Agents; Computer Simulation; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inflammation; Lipoxygenase Inhibitors; Male; Mice; Molecular Docking Simulation; Monocytes; Neutrophils; Pain; Prostaglandin-E Synthases; Salvia

2017
Elucidation of the biosynthesis of carnosic acid and its reconstitution in yeast.
    Nature communications, 2016, 10-05, Volume: 7

    Topics: Abietanes; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Escherichia coli; Genetic Vectors; Humans; Magnetic Resonance Spectroscopy; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Oxidants; Oxygen; Phylogeny; Rosmarinus; Saccharomyces cerevisiae; Salvia; Spectrometry, Mass, Electrospray Ionization

2016
Nano-liquid Chromatography-orbitrap MS-based Quantitative Proteomics Reveals Differences Between the Mechanisms of Action of Carnosic Acid and Carnosol in Colon Cancer Cells.
    Molecular & cellular proteomics : MCP, 2017, Volume: 16, Issue:1

    Topics: Abietanes; Chromatography, Liquid; Colonic Neoplasms; Endoplasmic Reticulum Stress; Gene Expression Regulation, Neoplastic; Homeostasis; HT29 Cells; Humans; Isotope Labeling; Proteasome Endopeptidase Complex; Proteomics; Signal Transduction; Tandem Mass Spectrometry; Unfolded Protein Response

2017
Comparative Study of Green Sub- and Supercritical Processes to Obtain Carnosic Acid and Carnosol-Enriched Rosemary Extracts with in Vitro Anti-Proliferative Activity on Colon Cancer Cells.
    International journal of molecular sciences, 2016, Dec-07, Volume: 17, Issue:12

    Topics: Abietanes; Biphenyl Compounds; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Colonic Neoplasms; Gas Chromatography-Mass Spectrometry; HCT116 Cells; HT29 Cells; Humans; Mass Spectrometry; Picrates; Plant Extracts; Rosmarinus

2016
One-step isolation of carnosic acid and carnosol from rosemary by centrifugal partition chromatography.
    Journal of separation science, 2017, Volume: 40, Issue:5

    Topics: Abietanes; Chromatography; Plant Extracts; Rosmarinus

2017
Differential activation of pregnane X receptor by carnosic acid, carnosol, ursolic acid, and rosmarinic acid.
    Pharmacological research, 2017, Volume: 120

    Topics: Abietanes; Animals; Cell Line; Cinnamates; Depsides; Gene Expression Regulation; Hep G2 Cells; Humans; Mice; Plant Extracts; Pregnane X Receptor; Rats; Receptors, Steroid; Rosmarinic Acid; Rosmarinus; Triterpenes; Ursolic Acid

2017
The effect of rosemary (Rosmarinus officinalis L.) extract on the oxidative stability of lipids in cow and soy milk enriched with fish oil.
    Food chemistry, 2018, Oct-15, Volume: 263

    Topics: Abietanes; Animals; Antioxidants; Fish Oils; Food Storage; Food, Fortified; Lipids; Milk; Oxidation-Reduction; Plant Extracts; Rosmarinus; Soy Milk

2018
Cytotoxic Tolerance of Healthy and Cancerous Bone Cells to Anti-microbial Phenolic Compounds Depend on Culture Conditions.
    Applied biochemistry and biotechnology, 2019, Volume: 188, Issue:2

    Topics: Abietanes; Animals; Anti-Infective Agents; Anticarcinogenic Agents; Bone Neoplasms; Cell Culture Techniques; Cell Line; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Humans; Limb Salvage; Mesenchymal Stem Cells; Mice; Osteosarcoma; Tissue Engineering

2019
Development and Validation of an Analytical Method Based on HPLC-ELSD for the Simultaneous Determination of Rosmarinic Acid, Carnosol, Carnosic Acid, Oleanolic Acid and Ursolic Acid in Rosemary.
    Molecules (Basel, Switzerland), 2019, Jan-17, Volume: 24, Issue:2

    Topics: Abietanes; Calibration; Chromatography, High Pressure Liquid; Cinnamates; Depsides; Limit of Detection; Oleanolic Acid; Reproducibility of Results; Rosmarinic Acid; Scattering, Radiation; Triterpenes; Ursolic Acid

2019
Comparative study of rosemary extracts and several synthetic and natural food antioxidants. Relevance of carnosic acid/carnosol ratio.
    Food chemistry, 2020, Mar-30, Volume: 309

    Topics: Abietanes; Antioxidants; Ascorbic Acid; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Food Additives; Plant Extracts; Rosmarinus; Tocopherols

2020
Sequential extraction of carnosic acid, rosmarinic acid and pigments (carotenoids and chlorophylls) from Rosemary by online supercritical fluid extraction-supercritical fluid chromatography.
    Journal of chromatography. A, 2021, Feb-22, Volume: 1639

    Topics: Abietanes; Antioxidants; Carotenoids; Chlorophyll; Chromatography, High Pressure Liquid; Chromatography, Supercritical Fluid; Cinnamates; Depsides; Kinetics; Plant Extracts; Reference Standards; Rosmarinic Acid; Rosmarinus

2021
Pharmacokinetic Analysis of Carnosic Acid and Carnosol in Standardized Rosemary Extract and the Effect on the Disease Activity Index of DSS-Induced Colitis.
    Nutrients, 2021, Feb-27, Volume: 13, Issue:3

    Topics: Abietanes; Administration, Oral; Animals; Colitis; Dextran Sulfate; Gene Expression Regulation; HT29 Cells; Humans; Male; Mice; Plant Extracts; Rosmarinus; Zonula Occludens-1 Protein

2021
Carnosic Acid and Carnosol Activate AMPK, Suppress Expressions of Gluconeogenic and Lipogenic Genes, and Inhibit Proliferation of HepG2 Cells.
    International journal of molecular sciences, 2021, Apr-14, Volume: 22, Issue:8

    Topics: Abietanes; AMP-Activated Protein Kinases; Animals; Apoptosis; Cell Proliferation; Fatty Acids; Gene Expression Regulation; Gluconeogenesis; HEK293 Cells; Hep G2 Cells; Humans; Lipogenesis; Mice; Oxidation-Reduction; Phosphorylation; Plant Extracts; Rosmarinus; Tumor Suppressor Protein p53; Up-Regulation

2021
Exploring volatile aroma and non-volatile bioactive compounds diversity in wild populations of rosemary (Salvia rosmarinus Schleid.).
    Food chemistry, 2023, Mar-15, Volume: 404, Issue:Pt A

    Topics: Odorants; Plant Breeding; Rosmarinus; Salvia; Volatile Organic Compounds

2023
The Use of Ultrasound-Assisted Maceration for the Extraction of Carnosic Acid and Carnosol from Sage (
    Molecules (Basel, Switzerland), 2023, Aug-16, Volume: 28, Issue:16

    Topics: Fish Oils; Methanol; Postmortem Changes; Salvia officinalis

2023