salvianolic-acid-c and salvianolic-acid-B

Since December 2019, the new coronavirus (also known as severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2, 2019-nCoV])-induced disease, COVID-19, has spread rapidly worldwide. Studies have reported that the traditional Chinese medicine Salvia miltiorrhiza possesses remarkable antiviral properties; however, the anti-coronaviral activity of its main components, salvianolic acid A (SAA), salvianolic acid B (SAB), and salvianolic acid C (SAC) is still debated. In this study, we used Cell Counting Kit-8 staining and flow cytometry to evaluate the toxicity of SAA, SAB, and SAC on ACE2 (angiotensin-converting enzyme 2) high-expressing HEK293T cells (ACE2

Topics: Alkenes; Angiotensin-Converting Enzyme 2; Benzofurans; Caffeic Acids; Cell Survival; COVID-19 Drug Treatment; HEK293 Cells; Humans; Lactates; Molecular Structure; Polyphenols; Protein Binding; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Virus Internalization