salvianolic-acid-B has been researched along with cholesteryl-ester-hydroperoxide* in 1 studies
1 other study(ies) available for salvianolic-acid-B and cholesteryl-ester-hydroperoxide
| Article | Year |
|---|---|
Comparison of the inhibitory effect against copper ion-induced oxidation in rat plasma after oral administration of salvianolic acid B and its decocted solutions.
The effects of salvianolic acid B (Sal B) decoction on antioxidative activities were evaluated. The 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging activity, Fe(2+)-chelating activity, reducing power, and total phenolic content of the Sal B-decocted solutions did not change significantly after decoction in an aqueous solution. However, the formation of cholesteryl ester hydroperoxide (CE-OOH) in rat blood plasma containing the Sal B-decocted solutions was more effectively inhibited than that of plasma containing the Sal B solution, regardless of the decoction time. In addition, the accumulation of CE-OOH in rat plasma after oral administration of the Sal B-decocted solutions was more effectively suppressed than when the Sal B solution was administered, considering the lag time. It is likely that the decoction was partly responsible for the increased antioxidant activity in blood plasma. Therefore, the Sal B-decocted solution may contribute more to antioxidant defense in blood than a Sal B solution that is not decocted. Topics: Administration, Oral; Animals; Antioxidants; Benzofurans; Biphenyl Compounds; Chelating Agents; Cholesterol Esters; Copper; Ions; Male; Oxidation-Reduction; Phenols; Picrates; Plant Extracts; Plant Preparations; Rats; Rats, Sprague-Dawley; Salvia | 2013 |