salicylic acid and probenecid

salicylic acid has been researched along with probenecid in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19909 (27.27)18.7374
1990's6 (18.18)18.2507
2000's11 (33.33)29.6817
2010's6 (18.18)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Grassl, SM; Holtzman, EJ; Race, JE; Williams, WJ1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Cihlar, T; Ho, ES1
Inui, K; Saito, H; Uwai, Y1
Cha, SH; Endou, H; Fukushima , JI; Goya, T; Kanai, Y; Kobayashi, Y; Sekine, T1
Cha, SH; Endou, H; Hosoyamada, M; Khamdang, S; Kimura, H; Narikawa, S; Sekine, T; Takeda, M1
Hori, S; Kikkawa, T; Mori, S; Ohtsuki, S; Otagiri, M; Takanaga, H; Terasaki, T1
Sweet, DH; Youngblood, GL1
Eraly, SA; Kaler, G; Khandelwal, A; Nagle, M; Nigam, SK; Swaan, PW; Truong, DM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Gozalbes, R; Pineda-Lucena, A1
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Bellman, K; Knegtel, RM; Settimo, L1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Chatton, JY; Roch-Ramel, F3
MacDougall, ML; Wiegmann, TB1
Harnish, PP; Samuel, K1
Roch-Ramel, F; Schild, L1
Bildstein, C; Liu, D; Mamelok, RD; Tse, SS1
Deguchi, Y; Kimura, R; Nozawa, K; Yamada, S; Yokoyama, Y1
Diezi, J; Guisan, B; Roch-Ramel, F1
POULSEN, H1
RENSCHLER, A; SCHOOG, M1
BLANCHARD, KC; MUDGE, GH; WEINER, IM1
BOGER, WP; PITTS, FW1
BOGER, WP; GALLAGHER, ME; PITTS, FW1
Bhattacharya, I; Boje, KM1
Bustamante, P; Escalera, B; Peña, MA; Reíllo, A; Sánchez, AB1

Reviews

1 review(s) available for salicylic acid and probenecid

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

32 other study(ies) available for salicylic acid and probenecid

ArticleYear
Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3).
    Biochemical and biophysical research communications, 1999, Feb-16, Volume: 255, Issue:2

    Topics: Amino Acid Sequence; Animals; Anion Transport Proteins; Biological Transport; Blotting, Northern; Carrier Proteins; Chromosomes, Human, Pair 11; Cloning, Molecular; Humans; Kidney; Mice; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Rats; Sequence Homology, Amino Acid; Xenopus laevis

1999
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Fluorescence-based assay for the interaction of small molecules with the human renal organic anion transporter 1.
    Analytical biochemistry, 2000, Jul-15, Volume: 283, Issue:1

    Topics: Animals; Anion Transport Proteins; Anions; Arylsulfonates; Boron Compounds; Carrier Proteins; CHO Cells; Cricetinae; DNA, Complementary; Dose-Response Relationship, Drug; Fluorescein; Fluoresceins; Fluorescent Dyes; Glutarates; Humans; Inhibitory Concentration 50; Kinetics; Models, Chemical; Spectrometry, Fluorescence; Time Factors; Transfection

2000
Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter.
    European journal of pharmacology, 2000, Dec-01, Volume: 409, Issue:1

    Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Carrier Proteins; Kinetics; Methotrexate; Oocytes; Probenecid; Uricosuric Agents; Xenopus laevis

2000
Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney.
    Molecular pharmacology, 2001, Volume: 59, Issue:5

    Topics: Amino Acid Sequence; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 11; Cloning, Molecular; Gene Library; Humans; Kidney Tubules, Proximal; Molecular Sequence Data; Oocytes; Organic Anion Transporters, Sodium-Independent; Sequence Homology, Amino Acid; Tissue Distribution; Transfection; Xenopus laevis

2001
Characterization of methotrexate transport and its drug interactions with human organic anion transporters.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cells, Cultured; Humans; Indomethacin; Kinetics; Liver-Specific Organic Anion Transporter 1; Methotrexate; Mice; Mice, Transgenic; Nerve Tissue Proteins; Organic Anion Transporters, Sodium-Independent; Phenylbutazone; Potassium Channels; Potassium Channels, Tandem Pore Domain; Probenecid

2002
Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:3

    Topics: Animals; Biological Transport; Blood-Brain Barrier; Capillaries; Disease Models, Animal; Estrone; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Osteosclerosis; Penicillin G; RNA, Messenger

2004
Identification and functional assessment of the novel murine organic anion transporter Oat5 (Slc22a19) expressed in kidney.
    American journal of physiology. Renal physiology, 2004, Volume: 287, Issue:2

    Topics: 2,4-Dichlorophenoxyacetic Acid; Amino Acid Sequence; Animals; Dose-Response Relationship, Drug; Electrochemistry; Estrone; Female; Glutarates; Kidney; Mice; Molecular Sequence Data; Mycotoxins; Ochratoxins; Oocytes; Organic Anion Transporters; Potassium; Rats; RNA, Messenger; Salicylates; Tissue Distribution; Xenopus laevis

2004
Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.
    The Journal of biological chemistry, 2007, Aug-17, Volume: 282, Issue:33

    Topics: Binding Sites; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Structure; Organic Anion Transport Protein 1; Organic Anion Transporters; Static Electricity; Substrate Specificity

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Transport of salicylic acid through monolayers of a kidney epithelial cell line (LLC-PK1).
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:2

    Topics: Biological Transport; Cell Line; Cell Membrane Permeability; Hydrogen-Ion Concentration; Kidney; Probenecid; Salicylates; Salicylic Acid

1992
Nonionic diffusion of salicylic acid through MDCK cell monolayers.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:3

    Topics: Animals; Cell Membrane Permeability; Cells, Cultured; Diffusion; Dogs; Hydrogen-Ion Concentration; Kidney Cortex; Probenecid; Salicylates; Salicylic Acid

1992
Passive permeability of salicylic acid in renal proximal S2 and S3 tubules.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:3

    Topics: Absorption; Animals; Carbon Radioisotopes; Drug Interactions; Female; Hydrogen-Ion Concentration; Kidney Tubules, Proximal; Male; Permeability; Probenecid; Rabbits; Salicylates; Salicylic Acid

1991
Urate excretion by the isolated perfused rat kidney and modification by drugs.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1989, Volume: 192, Issue:3

    Topics: Animals; Furosemide; Glomerular Filtration Rate; Kidney; Natriuresis; Oxonic Acid; Perfusion; Probenecid; Pyrazinamide; Rats; Salicylates; Salicylic Acid; Uric Acid

1989
Pharmacologic manipulation of the flushing action of cerebrospinal fluid. Effect on CSF diatrizoate levels.
    Investigative radiology, 1988, Volume: 23, Issue:12

    Topics: Acetazolamide; Aminophylline; Animals; Bucladesine; Carbachol; Cerebrospinal Fluid; Dexamethasone; Diatrizoate; Digoxin; Furosemide; Male; Premedication; Probenecid; Rats; Rats, Inbred Strains; Ritodrine; Salicylates; Salicylic Acid

1988
Transport of salicylate in proximal tubule (S2 segment) isolated from rabbit kidney.
    The American journal of physiology, 1988, Volume: 254, Issue:4 Pt 2

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Carbon Radioisotopes; Female; In Vitro Techniques; Kidney Tubules, Proximal; Kinetics; Male; Ouabain; Probenecid; Rabbits; Reference Values; Salicylates; Salicylic Acid

1988
Effects of analogs of salicylate on p-aminohippurate uptake into basal-lateral membranous vesicles.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:3

    Topics: Aminohippuric Acids; Animals; Basement Membrane; Benzoates; Biological Transport, Active; Kidney Cortex; Mersalyl; Organomercury Compounds; p-Aminohippuric Acid; Probenecid; Rabbits; Salicylates; Salicylic Acid; Sulfhydryl Compounds; Thimerosal

1984
Quantitative evaluation of brain distribution and blood-brain barrier efflux transport of probenecid in rats by microdialysis: possible involvement of the monocarboxylic acid transport system.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2

    Topics: Animals; Anion Transport Proteins; beta-Alanine; Blood-Brain Barrier; Brain; Carrier Proteins; Ethylmaleimide; Kinetics; Male; Metabolic Clearance Rate; Microdialysis; Probenecid; Rats; Rats, Wistar; Salicylates; Salicylic Acid; Tissue Distribution

1997
Effects of uricosuric and antiuricosuric agents on urate transport in human brush-border membrane vesicles.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2

    Topics: Aged; Benzbromarone; Biological Transport; Biphenyl Compounds; Carbon Radioisotopes; Diuretics; Ethambutol; Humans; Imidazoles; Kidney Cortex; Kidney Neoplasms; Kinetics; Losartan; Microvilli; Middle Aged; Probenecid; Pyrazinamide; Salicylates; Salicylic Acid; Sulfinpyrazone; Tetrazoles; Ticrynafen; Uric Acid; Uricosuric Agents

1997
Inhibition of uric acid excretion in rabbits given probenecid or salicylic acid.
    Acta pharmacologica et toxicologica, 1955, Volume: 11, Issue:3

    Topics: Animals; Biological Transport; Body Fluids; Humans; Kidney; Lagomorpha; Probenecid; Rabbits; Salicylic Acid; Uric Acid

1955
[Blocking of salicylic acid excretion by benemid].
    Zeitschrift fur Haut- und Geschlechtskrankheiten, 1957, Aug-01, Volume: 23, Issue:3

    Topics: Body Fluids; Humans; Probenecid; Salicylic Acid

1957
FACTORS INFLUENCING RENAL EXCRETION OF FOREIGN ORGANIC ACIDS.
    The American journal of physiology, 1964, Volume: 207

    Topics: Acetates; Anilides; Animals; Benzoates; Benzothiadiazines; Bicarbonates; Dinitrophenols; Dogs; Fluids and Secretions; Gentisates; Hydrogen-Ion Concentration; Kidney; Kidney Tubules; Metabolism; Nitrobenzenes; p-Aminohippuric Acid; Phenylbutazone; Probenecid; Quinolines; Renal Elimination; Research; Salicylic Acid; Succinates; Sulfinpyrazone; Uricosuric Agents; Urine

1964
Influence of p-(di-n-propylsulfamyl)-benzoic acid, "benemid", on para-aminosalicylic acid (PAS) plasma concentrations.
    American review of tuberculosis, 1950, Volume: 61, Issue:6

    Topics: Amino Acids; Aminosalicylic Acid; Benzoic Acid; Leadership; Probenecid; Salicylic Acid

1950
Benemid and carinamide: comparison of effect on para-aminosalicylic acid (PAS) plasma concentrations.
    The Journal of laboratory and clinical medicine, 1950, Volume: 36, Issue:2

    Topics: Amino Acids; Aminosalicylic Acid; Probenecid; Salicylic Acid; Sulfonamides

1950
Potential gamma-hydroxybutyric acid (GHB) drug interactions through blood-brain barrier transport inhibition: a pharmacokinetic simulation-based evaluation.
    Journal of pharmacokinetics and pharmacodynamics, 2006, Volume: 33, Issue:5

    Topics: Administration, Oral; Animals; Area Under Curve; Biological Transport; Blood-Brain Barrier; Brain; Carrier Proteins; Computer Simulation; Dose-Response Relationship, Drug; Drug Interactions; Humans; Hydroxybutyrates; Injections, Intraperitoneal; Injections, Intravenous; Male; Models, Biological; Pilot Projects; Probenecid; Rats; Rats, Sprague-Dawley; Reflex; Reproducibility of Results; Salicylic Acid

2006
Thermodynamics of cosolvent action: phenacetin, salicylic acid and probenecid.
    Journal of pharmaceutical sciences, 2009, Volume: 98, Issue:3

    Topics: Calorimetry, Differential Scanning; Phenacetin; Probenecid; Salicylic Acid; Solubility; Solvents; Temperature; Thermodynamics

2009