salicylic acid and diazepam

salicylic acid has been researched along with diazepam in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19905 (15.63)18.7374
1990's7 (21.88)18.2507
2000's11 (34.38)29.6817
2010's8 (25.00)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Andersson, K; Borg, P; Frostell-Karlsson, A; Hämäläinen, M; Karlsson, R; Remaeus, A; Roos, H1
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Caron, G; Ermondi, G1
Abraham, MH; Acree, WE; Ibrahim, A1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Avdeef, A; Tam, KY1
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Cao, Z; Deng, Y; Li, Y; Liu, H; Qiang, X; Song, Q; Tan, Z; Tian, C; Yang, Z1
Carrai, M; Pacifici, GM; Rizzo, G; Viani, A1
Nanbo, T1
Cappiello, M; Pacifici, GM; Viani, A1
Brennan, SO; Galliano, M; Kragh-Hansen, U; Sugita, O1
Kragh-Hansen, U3
Nguyen, P; Pibouin, M; Renouard, A; Tillement, JP; Zini, R1
Cross, SE; Roberts, MS; Wu, Z1
Johnson, JA; Livingston, TN1
Gunaratna, C; Kissinger, PT1
Briñón, MC; Moroni, GN; Quevedo, MA1
Li, J; Sun, X; Wang, N; Xu, F; Yang, C; Zhang, Z1
Abbasnejad, M; Esmaeli-Mahani, S; Moghaddam Dizaj Herik, H; Motaghi, S; Sepehri, G1
Birkhan, J; Haim, S; Heifetz, M1
Kobayashi, K; Toda, Y1

Trials

1 trial(s) available for salicylic acid and diazepam

ArticleYear
Differences between blacks and whites in plasma protein binding of drugs.
    European journal of clinical pharmacology, 1997, Volume: 51, Issue:6

    Topics: Adult; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Anticoagulants; Black People; Blood Proteins; Diazepam; Disopyramide; Female; Humans; Male; Orosomucoid; Protein Binding; Salicylates; Salicylic Acid; Serum Albumin; Warfarin; White People

1997

Other Studies

31 other study(ies) available for salicylic acid and diazepam

ArticleYear
Biosensor analysis of the interaction between immobilized human serum albumin and drug compounds for prediction of human serum albumin binding levels.
    Journal of medicinal chemistry, 2000, May-18, Volume: 43, Issue:10

    Topics: Binding Sites; Biosensing Techniques; Digitoxin; Drug Stability; Humans; Molecular Weight; Naproxen; Orosomucoid; Pharmaceutical Preparations; Protein Binding; Quinine; Rifampin; Ritonavir; Serum Albumin; Solvents; Warfarin

2000
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
Discovery of novel 2,5-dihydroxyterephthalamide derivatives as multifunctional agents for the treatment of Alzheimer's disease.
    Bioorganic & medicinal chemistry, 2018, 12-15, Volume: 26, Issue:23-24

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Butyrylcholinesterase; Chelating Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Humans; Models, Molecular; Molecular Structure; Peptide Fragments; Phthalimides; Protein Aggregates; Structure-Activity Relationship

2018
The effect of ageing on plasma albumin and plasma protein binding of diazepam, salicylic acid and digitoxin in healthy subjects and patients with renal impairment.
    British journal of clinical pharmacology, 1992, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Blood Proteins; Diazepam; Digitoxin; Humans; Kidney Diseases; Middle Aged; Salicylates; Salicylic Acid; Serum Albumin

1992
Disposition kinetics in the rat fetus.
    Reproductive toxicology (Elmsford, N.Y.), 1991, Volume: 5, Issue:5

    Topics: Animals; Diazepam; Female; Fetus; Indomethacin; Kinetics; Maternal-Fetal Exchange; Models, Biological; Pregnancy; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Tissue Distribution

1991
Binding of diazepam, salicylic acid and digitoxin to albumin isolated from fetal and adult serum.
    Developmental pharmacology and therapeutics, 1991, Volume: 17, Issue:1-2

    Topics: Adult; Aging; Binding Sites; Diazepam; Digitoxin; Fetus; Humans; Salicylates; Salicylic Acid; Serum Albumin

1991
Binding of warfarin, salicylate, and diazepam to genetic variants of human serum albumin with known mutations.
    Molecular pharmacology, 1990, Volume: 37, Issue:2

    Topics: Binding Sites; Dialysis; Diazepam; Humans; Mutation; Protein Binding; Radioligand Assay; Salicylates; Salicylic Acid; Serum Albumin; Structure-Activity Relationship; Warfarin

1990
Evidence for a large and flexible region of human serum albumin possessing high affinity binding sites for salicylate, warfarin, and other ligands.
    Molecular pharmacology, 1988, Volume: 34, Issue:2

    Topics: Apazone; Binding Sites; Binding, Competitive; Chlorpropamide; Diazepam; Humans; Iopanoic Acid; Kinetics; Ligands; Phenylbutazone; Protein Binding; Salicylates; Salicylic Acid; Serum Albumin; Sulfathiazole; Sulfathiazoles; Warfarin

1988
Binding of 8-methoxypsoralen to human serum proteins and red blood cells.
    The British journal of dermatology, 1987, Volume: 117, Issue:2

    Topics: Binding Sites; Blister; Blood Proteins; Diazepam; Erythrocytes; Erythromycin; Humans; Indomethacin; Methoxsalen; Protein Binding; Salicylates; Salicylic Acid; Warfarin

1987
Relations between high-affinity binding sites of markers for binding regions on human serum albumin.
    The Biochemical journal, 1985, Feb-01, Volume: 225, Issue:3

    Topics: Binding Sites; Diazepam; Digitoxin; Humans; Models, Chemical; Phenolsulfonphthalein; Protein Binding; Salicylates; Salicylic Acid; Serum Albumin; Ultrafiltration; Warfarin

1985
Relations between high-affinity binding sites for L-tryptophan, diazepam, salicylate and Phenol Red on human serum albumin.
    The Biochemical journal, 1983, Jan-01, Volume: 209, Issue:1

    Topics: Binding Sites; Diazepam; Humans; Ligands; Models, Chemical; Phenolphthaleins; Phenolsulfonphthalein; Protein Binding; Salicylates; Salicylic Acid; Serum Albumin; Tryptophan

1983
The effect of protein binding on the deep tissue penetration and efflux of dermally applied salicylic acid, lidocaine and diazepam in the perfused rat hindlimb.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:1

    Topics: Administration, Cutaneous; Animals; Diazepam; Hindlimb; Lidocaine; Male; Perfusion; Protein Binding; Rats; Rats, Wistar; Salicylates; Salicylic Acid; Skin Absorption

1996
Application of microdialysis to study the in vitro metabolism of drugs in liver microsomes.
    Journal of pharmaceutical and biomedical analysis, 1997, Volume: 16, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Diazepam; Ibuprofen; Kinetics; Microdialysis; Microsomes, Liver; Nordazepam; Rats; Salicylates; Salicylic Acid; Temazepam

1997
Human serum albumin binding of novel antiretroviral nucleoside derivatives of AZT.
    Biochemical and biophysical research communications, 2001, Nov-09, Volume: 288, Issue:4

    Topics: Binding, Competitive; Chromatography, Gel; Decanoic Acids; Diazepam; Entropy; Humans; Models, Molecular; Prodrugs; Protein Binding; Protein Structure, Secondary; Reproducibility of Results; Salicylic Acid; Serum Albumin; Spectrophotometry, Ultraviolet; Substrate Specificity; Temperature; Ultrafiltration; Zidovudine

2001
Simultaneous determination of dipyridamole and salicylic acid in human plasma by high performance liquid chromatography-mass spectrometry.
    Biomedical chromatography : BMC, 2008, Volume: 22, Issue:2

    Topics: Chromatography, High Pressure Liquid; Diazepam; Dipyridamole; Humans; Reproducibility of Results; Rosiglitazone; Salicylic Acid; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Thiazolidinediones

2008
The anxiolytic effect of salicylic acid is mediated via the GABAergic system in the fear potentiated plus maze behavior in rats.
    Molecular biology reports, 2022, Volume: 49, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Anxiety Disorders; Behavior, Animal; Diazepam; Fear; GABAergic Neurons; Hippocampus; Male; Maze Learning; Rats; Rats, Wistar; Salicylic Acid

2022
Diffuse cutaneous scleroderma: an anaesthetic problem.
    Anaesthesia, 1972, Volume: 27, Issue:1

    Topics: Adolescent; Anesthesia, General; Diazepam; Eyelids; Halothane; Humans; Injections, Intravenous; Male; Nitrous Oxide; Scalp; Scleroderma, Systemic

1972
[Electrophysiology of intractable childhood epilepsy].
    No to hattatsu = Brain and development, 2014, Volume: 46, Issue:3

    Topics: Brain; Child; Child, Preschool; Diazepam; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Humans; Infant; Scalp; Sleep; Spasms, Infantile

2014