salicylic acid and aspirin

salicylic acid has been researched along with aspirin in 503 studies

Research

Studies (503)

TimeframeStudies, this research(%)All Research%
pre-1990192 (38.17)18.7374
1990's112 (22.27)18.2507
2000's90 (17.89)29.6817
2010's86 (17.10)24.3611
2020's23 (4.57)2.80

Authors

AuthorsStudies
Hannah, J; Holtz, WJ; Houser, RA; Jones, H; Kelly, KW; Matzuk, AR; Ruyle, WV; Sarett, LH; Shen, TY; Witzel, BE1
Fordice, MW; Greenwald, RB; Hannah, J; Jacobs, A; Jones, H; Ruyle, WV; Shen, TY; Walford, GL1
Gubernator, K; Kansy, M; Senner, F1
Apiwattanakul, N; Cha, SH; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Tsuda, M1
Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S1
Strassburg, CP; Tukey, RH1
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Carbonneau, MA; Cartron, E; Descomps, B; Fouret, G; Léger, CL1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Faassen, F; Spanings, H; Vogel, G; Vromans, H1
Eraly, SA; Kaler, G; Khandelwal, A; Nagle, M; Nigam, SK; Swaan, PW; Truong, DM1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Biondi, S; Cena, C; Coruzzi, G; Donnola, M; Fruttero, R; Gasco, A; Guaita, E; Lazzarato, L; Marini, E; Morini, G; Ongini, E; Rolando, B1
Bayram, E; Kufrevioglu, OI; Senturk, M; Supuran, CT1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Bandgar, BP; Gacche, RN; Hote, BS; Jalde, SS; Kinkar, SN; Korbad, BL; Patil, SA1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T1
Cena, C; Coruzzi, G; Fruttero, R; Gasco, A; Guaita, E; Guglielmo, S; Lazzarato, L; Lolli, ML; Marini, E; Morini, G; Rolando, B1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Hong, S; Jung, Y; Kang, S; Kim, J; Kim, YM; Yum, S1
Brun, P; Carta, D; Castagliuolo, I; Dean, A; Di Marco, V; Ferlin, MG; Surajit, P1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, X; Fu, J; Hu, Y; Sang, S; Shurlknight, KL; Soroka, DN; Zhu, Y1
Ban, HS; Ishihara, K; Nabeyama, W; Nakamura, H; Wada, H1
Baulard, AR; Biela, A; Blaise, M; Bourbiaux, K; Cantrelle, FX; Déprez, B; Djaout, K; Faïon, L; Flipo, M; Frita, R; Hanoulle, X; Herledan, A; Kremer, L; Leroux, F; Moune, M; Pintiala, C; Piveteau, C; Tanina, A; Vandeputte, A; Willand, N; Wintjens, R1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Asako, H; Granger, DN; Kubes, P; Wallace, J; Wolf, RE1
Davis, MB; Soybel, DI; West, AB1
Gutknecht, J1
Acitores, E; Legaz, ME; Valverde, F1
Becker, WM; Schlaak, M; Schubeler, K; Schulz, KH; Zhu, D1
Chaiyos, N; Itthipanichpong, C; Sirivongs, P; Wittayalertpunya, S1
Fresta, M; Micali, N; Puglisi, G; Villari, A2
Bianchi, A; Bonina, FP; Bousquet, E; Ciampini, N; Montenegro, L; Tirendi, S1
Klimes, J; Sedlácek, J; Sochor, J; Zahradnícek, M1
Belliardo, F; Bruno, G; La Rosa, C; Lucarelli, C; Pelloso, R1
Bock, R; Jurna, I; Spohrer, B1
Mayer, AL; Sitar, DS; Tenenbein, M1
Bromm, B; Rundshagen, I; Scharein, E1
Ito, S; Oka, R; Tsuchida, A; Yoshioka, H1
Efstathiou, CE; Ioannou, PC; Konstantianos, DG1
Albrecht, M; Brandt, KD; O'Bryan-Tear, G1
Artaza, MA; Castel, JM; Laporte, JR1
Florey, KG1
Vaara, M1
Umeki, S1
King, RL; Levine, RA; Nandi, J1
Bennett, PN; Notarianni, LJ; Patel, DK1
Cavrini, V; Di Pietra, AM; Gatti, R1
Bennett, PN; Notarianni, LJ; Ogunbona, A; Patel, DK1
Kelly, HW; McWilliams, BC; Vertrees, JE1
Bennett, PN; Hesse, A; Notarianni, LJ; Ogunbona, A; Patel, DK1
Drennen, JK; Lodder, RA1
Ankersen, M; Nielsen, KK; Senning, A1
Catanese, B; Guglielmotti, A; Martinelli, B; Romanelli, L; Valeri, P1
Corna, D; Garattini, S; Gaspari, F; Locatelli, M; Perico, N; Remuzzi, G1
Attardo Parrinello, G; Barzaghi, N; Gatti, G; Perucca, E; Vitiello, B1
Miners, JO1
Barlow, JC; Dillon, EC; Watson, WA; Wilton, JH1
Buyniski, JP; Cavanagh, RL; Schwartz, SE1
Cerletti, C; de Gaetano, G; Dejana, E; Latini, R1
Bull, R; Haug, A; Mazorow, DL; McGroarty, EJ1
Forn, J; García-Rafanell, J; Gomez, L; Ramis, J1
Husney, RM; Sagone, AL1
Buchanan, MR; Butt, RW; Hirsh, J; Markham, BA; Nazir, DJ1
Aihara, H; Higuchi, S; Otomo, S; Shioiri, Y; Tanaka, N1
Amezcua, JL; Favari, L; Mourelle, M1
Schrör, K; Verheggen, R2
Albors, M; De Castellarnau, C; Rutllant, ML; Sancho, MJ; Vila, L1
Bucchi, F; Cerletti, C; Chen, ZM; de Gaetano, G; Gambino, MC; Gori, G; Latini, R; Passaghe, S1
Atkinson, DC; Diamond, J; Zambraski, EJ1
Bochner, F; Lloyd, JV; Morris, PM; Siebert, DM; Williams, DB1
Day, RO; Lam, S; Paull, PD; Swanson, BR; Wade, DN; Williams, KM1
Danesh, JZ; Duncan, A; Mitchell, G; Russell, RI1
Anton, F; Forster, C; Handwerker, HO; Reeh, PW; Weber, E1
Cerletti, C; de Gaetano, G; Dejana, E; Domanin, M; Latini, R; Lauri, D; Lorenzi, G; Marchi, S; Urso, R1
Allen, A; Garner, A; Rowe, PH1
Artaza, MA; Castel, JM; Cusidó, E; Laporte, JR; Vidal, X1
Caveney, S1
Levy, G; Wientjes, MG1
Bourin, M; Kergueris, MF; Larousse, C; Lasserre, MP; Ortega, A1
Anttila, M; Kahela, P; Uotila, P1
Bellido, I; de la Cruz, JP; Pavia, J; Sánchez de la Cuesta, F1
Kay, JD1
Soper, BD; Tepperman, BL1
Helms, RA; Jabbour, JT; Walker, PC; Wall, HP1
Hiura, M; Kasama, T; Mayuzumi, K; Minato, M; Minohara, K; Nakai, M; Ohshiro, K; Sakaguchi, Y1
Buchanan, WW; Darke, AC; Grace, EM; Mewa, AA; Rosenfeld, JM; Sweeney, GD1
Ishihara, N; Kojima, S; Nakagawa, M; Shimokawa, T1
Bochner, F; Cleland, LG; Graham, GG; Imhoff, DM; Polverino, A; Rolan, PE; Tregenza, RA1
Vane, J1
Gaspari, F; Locatelli, M1
Chen, YC; Kuo, TL; Lee, TK1
Beswick, DT; Blake, DR; d'Assis-Fonseca, A; Unsworth, J1
Bianchine, JR; Gerber, N; Kershaw, RA; Mays, DC1
Bochner, F; Siebert, DM1
Ang, A; Chen, YC; Kuo, TL; Lee, TK; Lien, IN; Liu, MC1
Caldwell, J; Hutt, AJ; Smith, RL1
Peeters, PA; Raghoebar, M; van den Berg, WB; van Ginneken, CA1
Cerletti, C; de Gaetano, G; Dejana, E; Galletti, F; Latini, R; Marzot, M; Urso, R1
Amidon, GL; Fleisher, D; Lui, CY; Oberle, R1
Abernethy, DR; Boxenbaum, HG; Greenblatt, DJ; Harmatz, JS; Matlis, R; Ochs, HR; Shader, RI1
Chang, CW; Lau, AH; Schlesinger, PK1
Birkett, DJ; Grgurinovich, N; Miners, JO; Robson, RA; Whitehead, AG1
Brandt, JL; Chapron, DJ; Feig, PU; Gomolin, IH; Kramer, PA; Sweeney, KR1
Gryglewski, RJ; Marcinkiewicz, E; Michalska, Z; Radomski, M1
Abrams, WB; Conner, DP; Mojaverian, P; Rocci, ML; Vlasses, PH1
Cerletti, C; Costantini, V; De Amicis, G; de Gaetano, G; Dejana, E; Lorenzi, G1
Danon, A; Telias, ID; Zvi, ZB1
Hiraga, K; Takahashi, O1
Geday, E; Husted, SE; Mogensen, CE; Nielsen, HK; Petersen, T1
Clark, L; Cohen, MM; McCready, DR; Sevelius, H1
Ganguli, S; Miller, JD; Sperling, MA1
Drack, E; Halter, F; Scheurer, U1
Buchanan, MR; Butt, RW; Hirsh, J; Magas, Z; Nazir, DJ; van Ryn, J1
Hansen, D; Salmon, JA; Whittle, BJ1
Cerletti, C1
Lobeck, F; Spigiel, RW1
Chalmers, IM; Hunter, T; Sitar, DS1
Clark, JH; Fitzgerald, JF; Nagamori, K1
Breddin, HK; Mutschler, E; Rehders, K; Simrock, R; Spahn, H1
Cerletti, C; de Gaetano, G; Dejana, E; Garattini, S; Latini, R; Tognoni, G1
Bourne, DW; Heazlewood, VJ; Ho, PC; Triggs, EJ1
Mamolo, MG; Maurich, V; Vio, L1
Danesh, B; Omile, CI; Tebbett, IR1
Brandon, RA; Eadie, MJ; Smith, MT1
Altmayer, P; Cattarius-Korb, S; Krüger, B; Lang, E; Mutschler, E; Sörgel, F; Spahn, H1
Attarchi, F; Carstensen, JT; Hou, XP1
Feigal, D; Jang, H; Pollet, S; White, RH; Yim, CW1
Rácz, I; Ujhelyi, G1
Cerletti, C; de Gaetano, G; Dejana, E; Del Maschio, A; Galletti, F; Latini, R1
Shastri, RA1
Loftsson, T1
Igarashi, T; Kitagawa, H; Misawa, M; Nishimura, T; Sato, T; Ueno, K; Yanaura, S1
Jankowski, A; Skublicki, S; Szymański, W; Wichliński, LM1
Brantmark, B; Hedner, U; Melander, A; Wåhlin-Boll, E1
Alam, AS; Gregoriades, D; Imondi, AR1
Mazzeo, P; Quaglia, MG; Segnalini, F1
Alpsten, M; Bogentoft, C; Ekenved, G1
Frawley, VL; Ou, CN1
Hanley, SP; Hughes, J1
Bruce, IJ; Wilkie, D1
Thiessen, JJ2
Ellis, RP; Knight, AP; Lucas, MJ; Morris, CJ; Phillips, RW; Wise, CM1
Cerletti, C; De Gaetano, G; Doni, MG; Livio, M1
Hoak, JC1
Harding, PL; Krausse, EJ; Lolle, SJ; Morris, GP; Wallace, JL1
Gray, DA; Langrieger, N; Reschmaier, J; Simon, E1
O'Kruk, RJ; Paul, ML; Philp, RB1
Block, LH; Rhyner, K; Stenger, M1
Berlet, G; Chemnitius, KH; Schröber, R; Traeger, A; Zaumseil, J1
Cossum, PA; McLeod, LJ; Roberts, MS; Vial, JH1
Barary, MH; Korany, MA; Wahbi, AM1
Hozumi, K; Kitamura, K; Takagi, M1
Mason, WD1
Lee, CP; Martens, ME1
Brantmark, B; Forshell, GP; Fredholm, B; Hedner, U; Melander, A; Nitelius, E; Wåhlin-Boll, E1
Flouvat, B; Henry, JF; Rocher, I1
Koren, G; MacLeod, SM1
Neuvonen, PJ; Olkkola, KT1
Adams, MA; O'Kruk, RJ; Philp, RB1
Badcock, NR; Everett, DS; Penna, AC; Sansom, LN1
Beach, CA; Bianchine, JR; Gerber, N; Kershaw, RA; Mays, DC; Sharp, DE1
Isler, H; Jerusalem, F; Rhyner, K; Smith, M1
Bevitt, RN; Mather, JR; Sharman, DC1
Hoogmartens, J; Roets, E; Thomis, R1
Chen, P; Epstein, P; Fogel, J1
Pendleton, RG; Stavorski, JM1
Dahl, ML; Uotila, P1
Bergren, DR; Kincaid, RJ1
Cassell, S; Dromgoole, SH; Furst, DE; Paulus, HE1
Brooks, PM; Roberts, MS; Rumble, RH; Thomas, D; Wanwimolruk, S1
Bakar, SK; Niazi, S2
Amon, I; Amon, K; Zschiesche, A1
Coceani, F; Olley, PM; Salama, RB; Thiessen, JJ2
Bianchine, JR; Goldlust, MB; Harrison, LI; Kehe, CR; Kvam, DC1
Crean, GP; Hearns, J; Mitchell, KG1
Galante, RN; Grim, WM; Visalli, AJ1
Ashorobi, RB; Laniyonu, AA; Oyekan, AO1
Maedge, S; Sewing, KF; Weissenborn, U1
Breddin, HK; Lischke, V; Missalla, A; Schwidtal, P; Simrock, R1
Cerletti, C; de Castellarnau, C; de Gaetano, G; Dejana, E; Galletti, F; Latini, R; Livio, M1
Hansen, DG; Kauffman, GL; Ligumsky, M1
Kitamura, K; Majima, R1
Reidl, U1
Proost, JH; Van Imhoff, GW; Wesseling, H1
Innis, JD; Wenzel, DG1
Braithwaite, RA; Chand, S; Crome, P; Dawling, S1
Barcza, G; Lõrincz, M; Tátrai, E; Ungváry, G1
Guidi, G; Olzer, D; Schiavon, R; Zatti, M1
Mason, WD; Winer, N1
Anderson, WH; Czajka, PA; Mowry, JB; Sketris, IS; Stafford, DT1
Bochner, F; Byrne, G; Cham, BE; Gunsberg, M; Imhoff, DM1
Grossman, MI; Kauffman, GL; Ligumsky, M1
Rawlins, MD; Seymour, RA1
Alpsten, M; Bogentoft, C; Ekenved, G; Sölvell, L1
Pankey, JW; Pfeiffer, CD1
Brantmark, B; Melander, A; Wåhlin-Boll, E1
Bruno, R; Curto, M; Ponzetto, C; Rinaudo, MT1
Itami, T; Kanoh, S1
Flinn, PE; Jefferson, E; Kirchhoefer, RD1
Lücker, PW; Procaccini, R; Tilling, W; Vance, J; Wetzelsberger, N1
Geday, E; Husted, SE; Pedersen, AK; Petersen, T1
Schenk, GH; Street, KW1
Robert, A1
Carmichael, GR; Parrott, EL; Shah, SA1
Eppler, J; Fraga, C; Giesbrecht, E; Ito, S; Johnson, D; Rais, A; Verjee, Z; Wiggins, T1
Bacolod, M; Dawson, C; Gonzales, C; Kishore, V; Lopez-Anaya, A1
Azaroual, N; Imbenotte, M; Leclerc, F; Lhermitte, M; Maschke, S; Vermeersch, G1
Buckley, CE; Corder, EH1
Bttner, T; Gerlach, M; Kuhn, W; Müller, T1
Eppler, J; Johnson, D; Klein, J; Lee, S1
Ogawa, N; Ohdo, S; Song, JG1
Coudray, C; Fatôme, M; Favier, A; Martin, S; Talla, M1
Marangos, MN; Nicolau, DP; Nightingale, CH; Onyeji, CO1
Blondino, FE; Byron, PR1
Damiani, P; Ibáñez, G; Olivieri, AC1
Abdel-Rahman, MS; Rizk, M1
Berthon, G; Brumas, B; Brumas, V1
Castañeda-Hernández, G; Castillo-Méndez, MS; Flores-Murrieta, FJ; Granados-Soto, V; López-Muñoz, FJ1
Chey, WY; Levine, RA; Li, P; Zhou, L1
Hollman, PC; Janssen, PL; Katan, MB; Venema, DP1
Gazy, AA; Hassan, EM; Wahbi, AA1
Beving, H; Eksborg, S; Malmgren, RS; Nordlander, R; Olsson, P; Rydén, L1
Bartos, A; Gołkiewicz, W1
Cadórniga, R; Torrado, S1
Damme, B; Pankow, D; Schrör, K1
Casadevall, G; Franch, MA; Moreno, JJ; Queralt, J1
Baker, PV; Dickinson, RG; King, AR1
Ando, F; Arakawa, M; Kambara, K; Kano, A; Ohno, M; Segawa, T1
Amico, MC; Morrone, LA; Romanelli, L; Valeri, P1
Aihie, AP; Crome, P; Halpern, SM; Streete, PJ1
Li, YF; Moody, FG; Myers, SI; Russell, DH; Weisbrodt, NW1
Anderson, P; Andersson, R; Boréus, LO; Dahlén, B; Zetterström, O1
Amon, I; Franke, G; Siegmund, W; Zschiesche, M1
Bill, RL; Bowers, LD; Caywood, DD; Cipolle, RJ; Waters, DJ1
Binder, M; Zeiller, P1
Roberts, MS; Seddon, RJ; Shen, J; Wanwimolruk, S; Wilson, PD1
Fitzgerald, DJ; Keimowitz, RM; Mayo, G; Pulvermacher, G1
Goto, S; Matsumoto, Y; Ohsako, M1
Gwoździński, K; Watała, C1
Alemany, M; Bastida, E; Bozzo, J; Buchanan, MR; Hernández, R; Ordinas, A1
Becker, JA; Cochran, EB; Phillips, KR; Wideman, SD1
Chiao, SF; Chu, KM; Ho, ST; Ho, W; Hu, OY; Liu, HS1
Hjertén, S; Lundahl, P; Zhang, R; Zhang, Y1
Golovko, AI; Kliuntina, TV; Sofronov, GA1
Lorén, JG; Palomar, J; Puig, M; Viñas, M1
Daston, GP; Davis, DP; Kraus, AL; Odio, MR; York, RG1
Brecher, P; Chobanian, AV; Farivar, RS1
Chalasani, N; Jurado, RL; Roman, J1
Kreysel, HW; Reeh, PW; Steen, KH2
Freeman, DA; Hanlon, DW; Parton, K; Whittem, T1
Benedek, IH; Joshi, AS; King, SY; Kornhauser, DM; Pieniaszek, HJ1
Bias-Imhoff, U; Riechers, AM; Schulz, HU; Schurer, M; Schwantes, U1
Mellick, GD; Roberts, MS1
Grobecker, H; Jehnich, D; Kees, F1
Arroyo, MT; Cornudella, R; Esteva, F; Hirschowitz, BI; Lanas, AI; Sáinz, R1
Dzúrik, R; Krivosíková, Z; Spustová, V1
Benedito, MA1
Boland, CR; Brenner, DE; Crowell, J; Kelloff, G; Krishnan, K; Normolle, D; Peters-Golden, M; Rock, CL; Ruffin, MT; Vaerten, MA1
Dierickx, PJ; Janssen, L; Noble, E1
Foltínová, P; Grones, J1
Bolton, CH; Dwight, J; Hartog, M; Hopton, MI; Steer, K1
Mann, CK; Vickers, TJ; Wang, C1
Kelly, MT; McMahon, GP1
Bareggi, SR; De Benedittis, G; Pirola, R2
Ghahramani, P; Jackson, PR; Ramsay, LE; Rowland-Yeo, K; Yeo, WW1
Duffy, SJ; Esler, MD; Harper, RW; Meredith, IT; New, G; Tran, BT; Tudball, RN1
Fitzgerald, DJ; Kelly, MT; le Roy, S; McMahon, GP; O'Connor, SJ1
Barragán, M; Bellosillo, B; Castaño, E; Colomer, D; Gil, J; Montserrat, E; Piqué, M; Pons, G; Villamor, N1
Campanella, L; Crescentini, G; Sammartino, MP; Su, Y; Tomassetti, M1
Aubin, N; Carter, C; Curet, O; Deffois, A1
Bjørnsdottir, I; Hansen, SH; Jensen, ME1
Burda, K; Kokot, Z1
Andrieu, S; Berdeaux, A; Bévérelli, F; Giudicelli, JF; Lebret, M; Maclouf, J1
Al-Nasser, IA1
Makino, T; Tomida, Y1
Ishii, S; Ogawa, K; Sasaki, T; Senda, M1
Gmeiner, B; Held, I; Hermann, M; Hofbauer, R; Kapiotis, S; Seelos, C1
Castañeda-Hernández, G; Cruz, L; Navarrete, A1
Kinouchi, T; Onouchi, T; Shimizu, N1
Asea, A; Calderwood, SK; Coleman, CN; Stevenson, MA; Zhao, MJ1
Benfeldt, E1
Furuta, A; Imanishi, S; Kojima, H; Muramoto, N; Nakakita, M; Nakamura, K; Utsuno, K; Yamashita, K1
Exner, M; Gmeiner, BM; Held, I; Hermann, M; Hofbauer, R; Kapiotis, S; Seelos, C; Speiser, W1
Karabulut, AK; Pratten, MK; Ulger, H1
Fujita, A; Takeuchi, K; Tashima, K; Umeda, M1
Dietz, AB; Matasic, R; Vuk-Pavlovic, S1
Coudray, C; Favier, A1
Balakin, AA; Dodonov, AF; Novikova, LI; Talrose, VL1
Mrestani, Y; Neubert, RH1
Burg, MB; Ferguson, DR; Kirby, M; Michea, LF; Peters, EM; Rocha, GM; Xu, Y1
Blacklock, CJ; Gibson, IH; Kelly, CJ; Lawrence, JR; Malcolm, EA; Paterson, JR; Wiles, D1
Lawrence, JR; Paterson, JR2
An, D; Fan, G; Feng, M; Lin, M; Zhang, Z1
Jusko, WJ; Ramakrishnan, R1
Goździalska, A; Pajdak, W1
Fischer, B; Helm, H; Plochocka, P; Uhd Jepsen, P; Walther, M1
Barrett, J; Dorr, A; Liu, B; Oo, C; Ward, P1
Bazzi, MD1
Kato, S; Komoike, Y; Takeeda, M; Takeuchi, K; Tanaka, A1
Bernert, S; Leonhardt, A; Schmitz-Ziegler, G; Seyberth, HW; Watzer, B1
An, D; Li, YS; Wang, Y; Zhang, Z1
Dong, Y; Zhang, YN; Zhao, YZ1
Cronstein, BN; Montesinos, MC; Pillinger, M; Weissmann, G1
Hori, Y; Iwasaki, Y; Komiyayama, Y; Kuroki, Y; Yashiki, M1
Birkel, M; Hey, B; Loose, I; Lücker, PW; Schaefer, A2
De La Cruz, JP; González-Correa, JA; Guerrero, A; Márquez, E; Martos, F; Sánchez De La Cuesta, F1
Mo, JY; Wei, SL1
Chen, XS; Tian, J; Wang, RD1
HIGUCHI, T; ZUCK, DA1
SMITH, MJ1
McBAY, AJ; TINKER, RB1
HIGUCHI, T; LACH, JL1
SECRETAN, P1
EDWARDS, LJ; GORE, DN; RAPSON, HD; TAYLOR, MP1
CRONE, C; LASSEN, UV1
HABERLAND, GL; KOSTER, L; MEDENWALD, H1
FLECK, R1
CHRISTIAN, JE; CRABTREE, RE; DATA, JB1
PELLET, AC1
BORNKESSEL, S; RICHTER, J1
DELPHAUT, J; LANZA, M1
GAENSHIRT, H1
GREILING, H; SCHULER, B1
DIXON, AS; WOOD, PH1
CABIBBO, S; CANNATA, D; MANGIOLA, S; VALORA, N1
STEVENS, HM1
DOCZI, J; HILLYARD, IW; KIERNAN, PB1
KLENSHOJ, NC; LOCKIE, LM; WINTER, JA1
RUBIN, HS1
CHARLIER, H; COTTART, A; LAROCHE, MJ; SACQUET, E1
BRAUN, C; GUZMAN, F; LIM, RK; POTTER, GD; RODGERS, DW1
STOCKINGER, L1
BOSTROEM, H; LARSSON, KS1
KOSHY, KT1
BLAUG, SM; RICH, AG1
BEDFORD, C; CUMMINGS, AJ; MARTIN, BK1
DAVENPORT, HW1
Kumar, V; Sawyer, M1
Wu, KK1
Arrebola, MM; De La Cruz, JP; González-Correa, JA; Guerrero, A; Sánchez de la Cuesta, F1
Carbajal Rodríguez, L; Flores Pérez, J; Juárez Olguín, H; Lares Asseff, I; Loredo Abdalá, A1
He, L; Jiang, X; Li, S; Lin, S; Yang, J; Zhou, J1
MARCHE, J1
CLAPPISON, JW; HUMMEL, JP; PAUL, WD; ROUTH, JI1
Arrebola, MM; de la Cruz, JP; González-Correa, JA; Guerrero, A; Muñoz-Marín, J; Sánchez de la Cuesta, F1
Ishiwata, T; Ishizawa, F; Kimura, K; Kirihara, M; Namera, A; Nishida, M; Yashiki, M1
Abrantes, N; Gonçalves, F; Marques, CR1
NEWFIELD, H; PARIS, L1
Grove, A; Wilkinson, SP1
Nulton-Persson, AC; Sadek, HA; Szweda, LI1
Horiuchi, T; Kinouchi, T; Onouchi, T1
Berta, GN; Cesano, L; Corvetti, G; Di Carlo, F; Ghezzo, F; Mognetti, B; Pesce, E; Pirro, E; Zingaro, B1
Fuchs, D; Schennach, H; Schroecksnadel, K; Winkler, C; Wirleitner, B1
Hwang, B; Jeong, GT; Kim, D; Kim, SW; Park, DH; Ryu, HW; Woo, JC1
Bigler, J; Kuehl, GE; Lampe, JW; Potter, JD1
Baxter, G; Duthie, G; Lawrence, J; Paterson, J1
Bowen, ID; Mahdi, AJ; Mahdi, JG1
Cena, C; Fruttero, R; Gasco, A; Megson, IL; Rossi, AG; Turnbull, CM1
Parthasarathy, S; Santanam, N1
Ek, R; Heidarian, M; Mihranyan, A; Strømme, M1
Arthur, HM; Borthwick, GM; Burn, J; Johnson, AS; Partington, M; Wilson, R1
Ishimatsu, T; Nakashima, K; Ohwaki, Y; Wada, M; Yamane, T1
Asai, T; Esumi, K; Fujisawa, Y; Fujita, TD; Fujita, TK; Fujiwara, T; Hashimoto, Y; Hatoyama, T; Hino, F; Hishigaki, H; Horimoto, S; Ikeda, M; Imagawa, K; Katsumata, T; Kono, M; Maeda, T; Miyajima, N; Ogawa, T; Sasaki, S; Sesoko, S; Shimada, M; Sugawara, T; Suzuki, E; Suzuki, M; Tokushige, H; Tsuzuki, Y; Yamamoto, T; Zaima, H1
Assi, SA; El-Yazbi, FA; Hammud, HH1
Pierpoint, WS1
Král, V; Sessler, JL; Shishkanova, TV; Sýkora, D1
del Valle, C; Ferrit, M; Martínez, F1
Djurić, Z; Ibrić, S; Jovanović, M; Lucić, B; Parojcić, J; Solomun, L1
Cerletti, C; Crescente, M; de Gaetano, G1
Dehghani, Z; Hemmateenejad, B; Khabnadideh, S; Rezaei, Z1
Bigler, J; Chen, Y; Kuehl, GE; Lampe, JW; Rimorin, CF; Schwarz, Y; Shen, DD1
De La Cruz, JP; González-Correa, JA; Guerrero, A; López-Villodres, JA; Muñoz-Marín, J; Navas, MD; Torres, JA1
Ageda, S; Fuke, C; Ihama, Y; Miyazaki, T1
Lafont, O1
Bae, SK; Jung, EJ; Kim, HS; Liu, KH; Park, KM; Seo, KA; Shin, JG; Shon, JH; Yeo, CW1
Grischkowsky, D; Harsha, SS; Laman, N1
Boskovic, M; Injac, R; Karljikovic-Rajic, K; Prijatelj, M; Srdjenovic, B; Strukelj, B1
Rao, GH1
Choi, CI; Gao, L; Joseph, S; Kopelovich, L; Patlolla, JM; Rao, CV; Rigas, B; Steele, VE1
Furtado, CM; Sola-Penna, M; Spitz, GA; Zancan, P1
Baxter, G; Dreyer, JS; Flynn, R; Halket, JM; Lawrence, JR; Paterson, JR1
James Kallail, K; Kramer, KM; Kumar, G; Maalouf, R; Mosley, M1
Bark, N; Blombäck, M; He, S; Svensson, J; Wang, H1
Pesola, GR1
Barthélémy, C; Jansen, JB; Janssen, MJ; Joiris, E; Laheij, RJ; Odou, P; Peters, WH; Smits, P; van Oijen, MG1
Beyenhof, J; Boulet, J; Grover, G; Koetzner, L; Maselli, H; Xu, X1
Dhanapal, LP; Morse, AN1
Alkarrawi, MA; Bowen, ID; Mahdi, AJ; Mahdi, JG; Pepper, CJ1
Kock, JL; Kriel, WM; Leeuw, NJ; Ncango, DM; Pohl, CH; Swart, CW; van Wyk, PW1
Chaudhary, A; Prabhu, S; Wang, J1
Bica, K; Nieuwenhuyzen, M; Rijksen, C; Rogers, RD1
Enache, TA; Fatibello-Filho, O; Oliveira-Brett, AM1
Ikegaya, H; Kato, H; Yoshimoto, K1
Boutaud, O; Oates, JA1
Chen, DM; Huang, LL; Ihsan, A; Wang, X; Yuan, ZH1
Elend, D; Pieles, U; Shahgaldian, P1
Chrubasik, S; Magora, F; Vlachojannis, J1
Bathaie, SZ; Kazemi, SH; Mousavi, MF; Yousef Elahi, M1
Gualandi, I; Scavetta, E; Tonelli, D; Zappoli, S1
Cena, C; Fruttero, R; Gasco, A; Lazzarato, L; Lupino, E; Marini, E; Piccinini, M; Ramondetti, C; Tosco, P1
Al-Haza'a, A; Bowen, ID; Brennan, P; Buggins, AG; Fegan, C; Hewamana, S; Lin, TT; Mahdi, AJ; Mahdi, E; Mahdi, JG; Morgan, L; Pearce, L; Pepper, C; Walsby, E1
Abedi, G; Hatambeygi, N; Talebi, M1
Ajjala, D; Kandikere, V; Mudigonda, K; Nirogi, R; Suraneni, R; Thoddi, P1
Barbarulo, A; Felli, MP; Frati, L; Gaudio, C; Gazzaniga, P; Guerriero, R; Lotti, LV; Mattiello, T; Pucci, B; Pulcinelli, FM; Trifirò, E1
Alizadeh, N; Ameli, A1
Hammer, M; Voelker, M1
Shaw, LH; Tsai, TH1
Ayyadevera, S; Ding, Z; Goyal, T; Hearnsberger, E; Khaidakov, M; Mehta, JL; Mitra, S; Wang, X1
He, H; Hong, M; Meng, J; Tang, X; Yan, X; Zhang, C1
Fung, KP; Lau, BS; Leung, PC; Wang, S; Zhang, Z; Zhou, L; Zuo, Z1
Hoshina, K; Manita, S; Matsuzawa, S; Miyata, Y; Ooie, T; Sasahara, T; Sueyoshi, S; Yasue, T1
Hotha, KK; Kolagatla, PR; Venkateswarlu, V; Vijaya Bharathi, D1
Ebner, J; Hobl, EL; Jilma, B; Schmid, RW1
Aluganti Narasimhulu, C; Kamble, P; Nandave, M; Parthasarathy, S; Selvarajan, K1
Friebe, M; Kietzmann, M; Schumacher, S; Stahl, J1
Czlonkowski, A; Filipiak, KJ; Grygorowicz, T; Janicki, PK; Kaplon-Cieslicka, A; Opolski, G; Postula, M; Przybylkowski, A; Rosiak, M; Trzepla, E1
Gan, Z; Hung, I; Kong, X; Shan, M; Terskikh, V; Wu, G1
Belmar, J; Gallardo, MJ; Jemiola-Rzeminska, M; Strzalka, K; Suwalsky, M; Villena, F1
Chistyachenko, YS; Dushkin, AV; Khvostov, MV; Lyakhov, NZ; Polyakov, NE; Tolstikov, GA; Tolstikova, TG1
Alañón Molina, A; Martínez Ferreras, F; Murillo Pulgarín, JA1
Castillo, S; Giménez, MJ; Guillén, F; Martínez-Romero, D; Serrano, M; Valero, D; Valverde, JM2
Erastov, AA; Kostanyan, AE; Shishilov, ON1
Auroux, A; Krmar, M; Otman, O; Rac, V; Rakić, V1
Abe, T; Komatsu, M; Nakajima, K; Oriyama, T; Suzuki, H; Uchino, T; Yanagihara, Y1
Chollet, JF; Dédaldéchamp, F; Fleurat-Lessard, P; Roblin, G; Rocher, F; Saeedi, S1
Aluganti Narasimhulu, C; Jiang, X; Kamble, P; Litvinov, D; Parthasarathy, S1
Zhang, J1
Bojić, M; Guengerich, FP; Nagy, LD; Sedgeman, CA1
Huang, X; Liu, C; Wu, Y; Zhao, L1
Bermejo, M; Casabó, VG; Cuesta-Gragera, A; García-Arieta, A; González-Álvarez, I; Mangas-Sanjuan, V; Navarro-Fontestad, C; Trocóniz, IF1
Acharya, S; Daniel, A; Gyadangi, B; Ramsamy, S1
Banti, CN; Gkaniatsou, EI; Hadjikakou, SK; Kourkoumelis, N; Manoli, M; Skoulika, S; Tasiopoulos, AJ1
Koner, AL; Mallick, S; Pal, K1
Bianchi, ME; Carbone, M; De Marchis, F; Flores, EG; Gaudino, G; Giorgi, C; Jennings, CJ; Jube, S; Kanodia, S; Larson, D; Napolitano, A; Pagano, I; Pass, HI; Pastorino, S; Pellegrini, L; Pinton, P; Powers, A; Preti, A; Tanji, M; Yang, H1
Agresti, A; Antonyak, M; Bianchi, ME; Cerione, RA; Choi, HW; De Marchis, F; Gentile, DR; Gorzanelli, A; Hamilton, K; Klessig, DF; Manohar, M; Micikas, RJ; Montelione, GT; Moreau, M; Park, SW; Preti, A; Schroeder, FC; Song, F; Swapna, GV; Tian, M; Venereau, E; Wang, H1
Eguchi, S; Hasegawa, S; Nakano, E; Okada, K; Sunagawa, A; Tanaka, M; Yamamoto, F; Yamamoto, R; Yokota, H1
Hu, T; Huang, J; Huang, X; Li, J; Li, L; Pappoe, F; Shen, C; Tang, H; Zhang, P; Zhang, W1
Choi, HW; Harraz, MM; Klessig, DF; Manohar, M; Park, SW; Schroeder, FC; Snyder, SH; Tian, M1
Chen, L; Han, WJ; Hu, SJ; Liu, XZ; Luo, C; Sun, XL; Wang, HB1
Ai, G; Bhat, GJ; Dachineni, R; Kumar, DR; Sadhu, SS; Tummala, H1
Aresta, A; Zambonin, C1
Klessig, DF1
Gaudriault, P; Jégou, B; Kristensen, DM; Lesné, L; Main, KM; Mazaud-Guittot, S; Serrano, T1
Abdelkawy, M; El-Ragehy, NA; Hassan, NY; Tantawy, MA1
Akdogan, Y; Cakan-Akdogan, G; Emrullahoglu, M; Tatlidil, D; Ucuncu, M1
Baxter, GJ; Lawrence, JR; Paterson, JR1
Chi, YC; Chiang, CP; Lai, CL; Lee, SL; Lee, SP; Lee, YP; Yin, SJ1
Bortolin, RH; Bravo, M; Brion, M; Carracedo, A; Concheiro, M; Cruz, A; Germano, JF; Hirata, MH; Hirata, RD; Iñiguez, A; López-Rivadulla, M; Luchessi, AD; Quintela, O; Silbiger, VN; Sousa, AG1
Du, S; Guo, S; Lu, Y; Pang, H; Tian, Z; Wang, M; Wu, H; Zhang, L; Zhang, Q1
Dial, EJ; Edler, S; Fang, D; Li-Geng, T; Lichtenberger, LM; Phan, T; Philip, J1
Duan, JA; Guo, JM; Li, JP; Liu, Y; Shang, EX; Tang, ZS; Zhao, BC; Zhao, J; Zhu, ZH1
Malakar, S1
Dempsey, DA; Klessig, DF1
Jin, J; Luo, X; Qian, C; Yang, M; Zuo, Z1
Bhat, GJ; Callegari, E; Dachineni, R; Kesharwani, SS; Kumar, DR; Sankaranarayanan, R; Seefeldt, T; Tummala, H1
Alemanno, L; Angiolillo, DJ; Frati, L; Guarino, ML; Klaus, V; Maltese, T; Massimi, I; Pulcinelli, FM1
Lu, Y; Tan, L; Tan, N; Xue, YT; Yu, GY1
Curtis, N; Zimmermann, P1
Amin, OA; El-Kimary, EI; El-Yazbi, FA; Khamis, EF; Younis, SE1
Gangopadhyay, D; Mishra, H; Mishra, PC; Singh, R; Singh, RK; Srivastava, A; Tiwari, MK1
Abd El-Aty, AM; Bekhit, AE; Choi, JM; Hacımüftüoğlu, A; Kang, YS; Kim, SK; Park, DH; Shim, JH; Shin, HC; Wang, J; Yoo, KH; Zhang, H; Zheng, W1
Berggren, M; Blomgran, R; Pushpamithran, G; Seitanidou, M; Simon, DT1
Alvarez, AM; Cadavid J, AP; Gil-Villa, AM; Rojas-López, M; Velásquez-Berrío, M1
Awad, N; Griffiths, G; Vega-Estévez, S1
Darabedian, N; Forster, ER; Hang, HC; Kim, AT; Pratt, MR; Shen, A; Yang, X1
Eisen, DP; Hansen, R; McEwen, P; Pandey, S; Roberts, JA; Wallis, SC1
Blackburn, KL; Carr, G; Rose, JL; Selman, BG1
García-Pastor, ME; Giménez, MJ; Guillén, F; Serrano, M; Valero, D; Valverde, JM; Zapata, PJ1
Abdelaleem, EA; Abdelhamid, NS; Abou El Ella, DA; Mahmoud, AM1
Abou-Kheir, W; Ausina, P; Branco, JR; Demaria, TM; Esteves, AM; Leandro, JGB; Mendonça, APM; Ochioni, AC; Oliveira, MF; Palhano, FL; Sola-Penna, M; Zancan, P1
Badrawy, M; El-Mammli, MY; Elmasry, MS; Hassan, WS; Serag, A1
Albanes, D; Alwers, E; Amitay, E; Baron, JA; Bermejo, JL; Berndt, SI; Bishop, DT; Brenner, H; Buchanan, DD; Butterworth, A; Campbell, PT; Casey, G; Castellví-Bel, S; Chan, AT; Chang-Claude, J; Drew, DA; Figueiredo, JC; Gallinger, S; Giles, GG; Gruber, SB; Gsur, A; Gunter, MJ; Hampel, H; Harrison, TA; Hoffmeister, M; Hopper, JL; Keku, TO; Kim, HR; Kweon, SS; Li, CI; Li, L; Lin, Y; Lindblom, A; Lindor, NM; Marchand, LL; Moreno, V; Newcomb, PA; Nounu, A; Peters, U; Pharoah, PDP; Platz, EA; Relton, CL; Rennert, G; Richmond, RC; Sakoda, LC; Schafmayer, C; Scherer, D; Schoen, RE; Slattery, ML; Stadler, ZK; Stewart, ID; Surendran, P; Ulrich, CM; van Dujinhoven, FJB; Van Guelpen, B; Vodicka, P; Vodickova, L; Wareham, NJ; Weinstein, SJ; White, E; Williams, AC; Wolk, A; Woods, MO; Wu, AH; Zheng, W1
Abdulwahab, S; Eissa, MS; Elsonbaty, A; Hassan, WS1
Cheng, S; Han, Y; Jiang, Y; Jin, T; Jin, Y; Kong, X; Li, M; Li, XL; Min, JZ; Mo, L; Xu, X1
Aono, Y; Horinaka, M; Iizumi, Y; Imai, A; Ishikawa, H; Mutoh, M; Nishimoto, E; Ono, H; Sakai, T; Takakura, H; Taniguchi, K; Yasuda, S1
Coetzee, JF; Curtis, AK; Fritz, BR; Kleinhenz, MD; Magnin, G; Martin, MS; Montgomery, SR; Weeder, M1
Chen, Z; Ding, Y; Fan, B; Zhu, C1
Chong, DP; Prince, KC; Richter, R; Sa'adeh, H; Vasilyev, V; Wang, F1
El Far, M; Etchegaray, JP; Krishnamoorthy, K; Rameshwar, P; Romagano, MP; Sherman, LS; Williams, SF1
Du, Y; Li, L; Li, X; Lv, Y; Tan, J; Zhai, X1
Guo, BY; Hao, J; Liu, JM; Ren, JL; Sun, YQ; Wang, CC; Yang, XL; Zhang, XR; Zhao, JJ; Zhao, Q1
Mohammad AmayrehDepartment Of Chemistry Faculty Of Science Al-Balqa Applied University Al-Salt Jordan, -1
Fan, Z; Qiu, Z; Wang, Y; Xie, Z; Yang, W; Ye, Y; Zhang, J; Zhou, H1
Dalessio, DJ1
Di Iorio, G; Sampaolo, S; Sanges, G1
Fiumara, A; Greco, F; Pavone, L; Sorge, G1
Barrett, TL; Doherty, SD; Joseph, AK1

Reviews

20 review(s) available for salicylic acid and aspirin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
Synthesis, properties and prodrug potential of 2-methyl-2-oxy- and 2-methyl-2-thio-4H-1,3-benzodioxin-4-ones.
    Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1989, Volume: 43, Issue:3

    Topics: Animals; Aspirin; Benzyl Alcohols; Dioxins; Hydrolysis; Models, Molecular; Molecular Structure; Prodrugs; Salicylates; Salicylic Acid

1989
Drug interactions involving aspirin (acetylsalicylic acid) and salicylic acid.
    Clinical pharmacokinetics, 1989, Volume: 17, Issue:5

    Topics: Antacids; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Aspirin; Charcoal; Contraceptive Agents; Drug Interactions; Glucocorticoids; Histamine H2 Antagonists; Humans; Salicylates; Salicylic Acid

1989
Pharmacology of platelet inhibition in humans: implications of the salicylate-aspirin interaction.
    Circulation, 1985, Volume: 72, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Blood Platelets; Blood Vessels; Cyclooxygenase Inhibitors; Drug Interactions; Female; Humans; Kinetics; Leukocytes; Male; Platelet Aggregation; Salicylates; Salicylic Acid; Superoxides; Thrombosis

1985
Gastroduodenal mucosal defence mechanisms and the action of non-steroidal anti-inflammatory agents.
    Scandinavian journal of gastroenterology. Supplement, 1987, Volume: 127

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bicarbonates; Duodenum; Gastric Mucosa; Intestinal Mucosa; Salicylates; Salicylic Acid

1987
Aspirin: plasma concentration and effects.
    Thrombosis research. Supplement, 1983, Volume: 4

    Topics: Animals; Aspirin; Fibrinolytic Agents; Half-Life; Humans; Salicylates; Salicylic Acid

1983
Mechanisms of action: aspirin.
    Thrombosis research. Supplement, 1983, Volume: 4

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Endothelium; Humans; Ibuprofen; In Vitro Techniques; Indomethacin; Salicylates; Salicylic Acid; Thromboxanes

1983
[Antiphlogistic effect of salicylic acid and its derivatives].
    Fortschritte der Medizin, 1993, Nov-30, Volume: 111, Issue:33

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Humans; Inflammation; Salicylates; Salicylic Acid

1993
[Salicylic acid, aspirin].
    Nihon rinsho. Japanese journal of clinical medicine, 1999, Volume: 57 Suppl

    Topics: Aspirin; Drug Monitoring; Humans; Salicylic Acid

1999
Salicylic acid: a link between aspirin, diet and the prevention of colorectal cancer.
    QJM : monthly journal of the Association of Physicians, 2001, Volume: 94, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Diet; Fruit; Humans; Salicylic Acid; Vegetables

2001
[Aspirin esterase: biochemical and clinical aspects of aspirin catabolism].
    Przeglad lekarski, 2001, Volume: 58, Issue:6

    Topics: Aspirin; Carboxylic Ester Hydrolases; Humans; Salicylic Acid

2001
[Practical analysis of toxic substances useful for clinical toxicology. 5--Salicylate salts].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2003, Volume: 16, Issue:1

    Topics: Adolescent; Aspirin; Chromatography, High Pressure Liquid; Colorimetry; Female; Humans; Salicylic Acid; Spectrophotometry, Ultraviolet; Suicide, Attempted

2003
Control of COX-2 and iNOS gene expressions by aspirin and salicylate.
    Thrombosis research, 2003, Jun-15, Volume: 110, Issue:5-6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; CCAAT-Enhancer-Binding Protein-beta; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Membrane Proteins; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prostaglandin-Endoperoxide Synthases; Salicylic Acid; Transcriptional Activation

2003
[Salicylic acid, aspirin].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Aspirin; Biomarkers; Chromatography, High Pressure Liquid; Drug Interactions; Drug Monitoring; Food-Drug Interactions; Humans; Salicylic Acid; Specimen Handling

2004
Is there a role for dietary salicylates in health?
    The Proceedings of the Nutrition Society, 2006, Volume: 65, Issue:1

    Topics: Anticarcinogenic Agents; Aspirin; Colonic Neoplasms; Fruit; Humans; Salicylic Acid; Vegetables

2006
The historical analysis of aspirin discovery, its relation to the willow tree and antiproliferative and anticancer potential.
    Cell proliferation, 2006, Volume: 39, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Aspirin; Benzyl Alcohols; Glucosides; History, 18th Century; History, 19th Century; History, 20th Century; History, 21st Century; History, Ancient; History, Medieval; Humans; Salicylic Acid; Salix

2006
Analgesic use - prevalence, biomonitoring and endocrine and reproductive effects.
    Nature reviews. Endocrinology, 2016, Volume: 12, Issue:7

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Commerce; Congenital Abnormalities; Drug Monitoring; Endocrine Disruptors; Environmental Exposure; Female; Humans; Ibuprofen; Meconium; Milk, Human; Molar; Pain; Pain Management; Pregnancy; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Salicylic Acid; Tooth, Deciduous; Urogenital Abnormalities

2016
Bioactive food chemicals and gastrointestinal symptoms: a focus of salicylates.
    Journal of gastroenterology and hepatology, 2017, Volume: 32 Suppl 1

    Topics: Aspirin; Basophils; Food Analysis; Food Hypersensitivity; Gastrointestinal Diseases; Humans; Immunologic Tests; Irritable Bowel Syndrome; Salicylic Acid

2017
The effect of aspirin on antibiotic susceptibility.
    Expert opinion on therapeutic targets, 2018, Volume: 22, Issue:11

    Topics: Anti-Bacterial Agents; Aspirin; Bacteria; Drug Interactions; Drug Resistance, Bacterial; Humans; Platelet Aggregation Inhibitors; Salicylic Acid

2018
Shared and Related Molecular Targets and Actions of Salicylic Acid in Plants and Humans.
    Cells, 2023, 01-04, Volume: 12, Issue:2

    Topics: Aspirin; Humans; Plants; Salicylic Acid

2023

Trials

33 trial(s) available for salicylic acid and aspirin

ArticleYear
Multiple-dose charcoal and whole-bowel irrigation do not increase clearance of absorbed salicylate.
    Archives of internal medicine, 1992, Volume: 152, Issue:2

    Topics: Administration, Oral; Adult; Aspirin; Charcoal; Female; Humans; Intestinal Absorption; Intestines; Male; Poisoning; Salicylates; Salicylic Acid; Therapeutic Irrigation

1992
Central analgesic effects of acetylsalicylic acid in healthy men.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:11

    Topics: Adult; Analgesics; Arousal; Aspirin; Double-Blind Method; Electric Stimulation; Electrodes; Electroencephalography; Evoked Potentials, Auditory; Humans; Male; Reaction Time; Salicylates; Salicylic Acid

1991
Large surface area activated charcoal and the inhibition of aspirin absorption.
    Annals of emergency medicine, 1989, Volume: 18, Issue:5

    Topics: Absorption; Adult; Aspirin; Charcoal; Double-Blind Method; Gastric Mucosa; Humans; Intestinal Absorption; Male; Random Allocation; Salicylates; Salicylic Acid; Surface Properties

1989
Measurement of the analgesic effects of aspirin with a new experimental algesimetric procedure.
    Pain, 1988, Volume: 32, Issue:2

    Topics: Analgesia; Analysis of Variance; Aspirin; Clinical Trials as Topic; Double-Blind Method; Humans; Male; Pain; Pain Measurement; Salicylates; Salicylic Acid

1988
Comparative efficacy study of chewable aspirin and acetaminophen in the antipyresis of children.
    Journal of clinical pharmacology, 1986, Volume: 26, Issue:2

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Body Temperature; Child; Child, Preschool; Chromatography, High Pressure Liquid; Humans; Salicylates; Salicylic Acid; Time Factors

1986
Comparative bioavailability of aspirin from buffered, enteric-coated and plain preparations.
    International journal of clinical pharmacology, therapy, and toxicology, 1986, Volume: 24, Issue:6

    Topics: Administration, Oral; Adult; Aspirin; Biological Availability; Buffers; Humans; Kinetics; Male; Random Allocation; Salicylates; Salicylic Acid; Tablets; Tablets, Enteric-Coated

1986
Evaluation of a potential drug interaction between sucralfate and aspirin.
    Clinical pharmacology and therapeutics, 1986, Volume: 39, Issue:2

    Topics: Adsorption; Adult; Aluminum; Aspirin; Drug Combinations; Drug Interactions; Gastric Mucosa; Hippurates; Humans; Kinetics; Male; Random Allocation; Salicylates; Salicylic Acid; Sucralfate

1986
Protection against aspirin-induced antral and duodenal damage with enprostil. A double-blind endoscopic study.
    Gastroenterology, 1985, Volume: 88, Issue:1 Pt 2

    Topics: Adolescent; Adult; Aspirin; Drug Evaluation; Duodenum; Enprostil; Female; Gastric Fundus; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Prostaglandins E, Synthetic; Pyloric Antrum; Random Allocation; Salicylates; Salicylic Acid

1985
The effect of antacid and aspirin on the bioavailability of isofezolac in man.
    International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:9

    Topics: Adult; Aluminum Compounds; Antacids; Anti-Inflammatory Agents; Aspirin; Biological Availability; Blood Proteins; Drug Interactions; Female; Humans; Kinetics; Phosphates; Protein Binding; Pyrazoles; Salicylates; Salicylic Acid

1984
Effect of gastric pH on antidotal efficacy of activated charcoal in man.
    International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:10

    Topics: Absorption; Adult; Antidotes; Aspirin; Charcoal; Disopyramide; Female; Gastric Acid; Gastric Acidity Determination; Humans; Magnesium Hydroxide; Male; Middle Aged; ortho-Aminobenzoates; Salicylates; Salicylic Acid

1984
Saline catharsis: effect on aspirin bioavailability in combination with activated charcoal.
    Journal of clinical pharmacology, 1982, Volume: 22, Issue:1

    Topics: Adult; Aspirin; Biological Availability; Cathartics; Charcoal; Feces; Female; Humans; Intestinal Absorption; Kinetics; Male; Salicylates; Salicylic Acid; Sodium; Sulfates

1982
Efficacy and pharmacokinetics of aspirin in post-operative dental pain.
    British journal of clinical pharmacology, 1982, Volume: 13, Issue:6

    Topics: Adult; Aspirin; Female; Half-Life; Humans; Kinetics; Male; Pain, Postoperative; Salicylates; Salicylic Acid; Tooth Extraction

1982
Inter-individual variations of the effect of low dose aspirin regime on platelet cyclooxygenase activity.
    Thrombosis research, 1994, Apr-01, Volume: 74, Issue:1

    Topics: Adult; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Humans; Male; Middle Aged; Prostaglandin-Endoperoxide Synthases; Reference Values; Salicylates; Salicylic Acid

1994
Effects of nocloprost clathrate on absorption of acetylsalicylic acid.
    International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:1

    Topics: Acetylation; Administration, Oral; Adult; Aspirin; beta-Cyclodextrins; Chromatography, High Pressure Liquid; Cyclodextrins; Drug Interactions; Hippurates; Humans; Intestinal Absorption; Male; Prostaglandins F, Synthetic; Salicylates; Salicylic Acid; Single-Blind Method; Vasodilator Agents

1994
Topical acetylsalicylic, salicylic acid and indomethacin suppress pain from experimental tissue acidosis in human skin.
    Pain, 1995, Volume: 62, Issue:3

    Topics: Acidosis; Administration, Topical; Adult; Aspirin; Cross-Over Studies; Double-Blind Method; Female; Humans; Indomethacin; Injections, Intradermal; Isotonic Solutions; Male; Middle Aged; Palliative Care; Pressure; Salicylates; Salicylic Acid; Skin Diseases

1995
Variability in the pharmacokinetics and pharmacodynamics of low dose aspirin in healthy male volunteers.
    Journal of clinical pharmacology, 1995, Volume: 35, Issue:12

    Topics: Adult; Aspirin; Humans; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Salicylates; Salicylic Acid

1995
Lack of influence of glycine on the single dose pharmacokinetics of acetylsalicylic acid in man.
    International journal of clinical pharmacology and therapeutics, 1996, Volume: 34, Issue:7

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Aspirin; Cross-Over Studies; Double-Blind Method; Glycine; Half-Life; Humans; Male; Salicylates; Salicylic Acid; Therapeutic Equivalency

1996
Dose-dependent competitive block by topical acetylsalicylic and salicylic acid of low pH-induced cutaneous pain.
    Pain, 1996, Volume: 64, Issue:1

    Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Pain; Palliative Care; Salicylates; Salicylic Acid; Skin

1996
Simultaneous determination of acetylsalicylic acid and salicylic acid in human plasma by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical applications, 1996, Feb-23, Volume: 677, Issue:1

    Topics: Analgesics, Non-Narcotic; Aspirin; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Quality Control; Reproducibility of Results; Salicylates; Salicylic Acid; Specimen Handling; Therapeutic Equivalency

1996
Suppression of human colorectal mucosal prostaglandins: determining the lowest effective aspirin dose.
    Journal of the National Cancer Institute, 1997, Aug-06, Volume: 89, Issue:15

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colon; Colorectal Neoplasms; Drug Administration Schedule; Female; Humans; Intestinal Mucosa; Male; Middle Aged; Prostaglandins; Rectum; Salicylates; Salicylic Acid; Time Factors

1997
Skin and plasma levels of acetylsalicylic acid: a comparison between topical aspirin/diethyl ether mixture and oral aspirin in acute herpes zoster and postherpetic neuralgia.
    European journal of clinical pharmacology, 1998, Volume: 54, Issue:3

    Topics: Acute Disease; Administration, Oral; Administration, Topical; Aged; Analgesics; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cross-Over Studies; Double-Blind Method; Ether; Female; Herpes Zoster; Herpesviridae Infections; Humans; Male; Middle Aged; Neuralgia; Pain; Pain Measurement; Salicylates; Salicylic Acid; Skin; Solvents; Treatment Outcome

1998
In vivo microdialysis for the investigation of drug levels in the dermis and the effect of barrier perturbation on cutaneous drug penetration. Studies in hairless rats and human subjects.
    Acta dermato-venereologica. Supplementum, 1999, Volume: 206

    Topics: Administration, Cutaneous; Administration, Oral; Adult; Animals; Area Under Curve; Aspirin; Female; Forearm; Humans; Keratolytic Agents; Male; Microdialysis; Middle Aged; Rats; Rats, Sprague-Dawley; Reference Values; Salicylic Acid; Skin; Skin Absorption; Time Factors

1999
Interactions of aspirin and salicylic acid with prednisolone for inhibition of lymphocyte proliferation.
    International immunopharmacology, 2001, Volume: 1, Issue:11

    Topics: Adult; Algorithms; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Lymphocyte Activation; Lymphocytes; Male; Models, Biological; NF-kappa B; Prednisolone; Salicylic Acid

2001
Lack of pharmacokinetic interaction between the oral anti-influenza prodrug oseltamivir and aspirin.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:6

    Topics: Acetamides; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Aspirin; Cross-Over Studies; Drug Interactions; Female; Hippurates; Humans; Male; Oseltamivir; Prodrugs; Salicylic Acid

2002
Low-dose aspirin in pregnancy: maternal and neonatal aspirin concentrations and neonatal prostanoid formation.
    Pediatrics, 2003, Volume: 111, Issue:1

    Topics: Aspirin; Blood Platelets; Dinoprostone; Epoprostenol; Female; Fetal Blood; Humans; Infant, Newborn; Pre-Eclampsia; Pregnancy; Prostaglandins; Salicylic Acid

2003
Pharmacokinetic interaction study of a fixed combination of 500 mg acetylsalicylic acid/30 mg pseudoephedrine versus each of the single active ingredients in healthy male volunteers.
    Arzneimittel-Forschung, 2003, Volume: 53, Issue:4

    Topics: Adrenergic alpha-Agonists; Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Aspirin; Drug Combinations; Drug Interactions; Ephedrine; Humans; Male; Salicylic Acid

2003
Differences in the effects of extended-release aspirin and plain-formulated aspirin on prostanoids and nitric oxide in healthy volunteers.
    Fundamental & clinical pharmacology, 2003, Volume: 17, Issue:3

    Topics: Adult; Aspirin; Cross-Over Studies; Delayed-Action Preparations; Dinoprost; Double-Blind Method; Epoprostenol; Female; Humans; Male; Nitric Oxide; Platelet Aggregation Inhibitors; Salicylic Acid; Thromboxane B2

2003
Relative bioavailability and bioequivalence of a newly developed fixed combination sachet of acetylsalicylic acid and pseudoephedrine compared with a preliminary combination.
    Methods and findings in experimental and clinical pharmacology, 2003, Volume: 25, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Aspirin; Biological Availability; Chemistry, Pharmaceutical; Creatine Kinase; Dizziness; Drug Administration Schedule; Drug Combinations; Ephedrine; Half-Life; Humans; Male; Middle Aged; Nausea; Powders; Salicylic Acid; Therapeutic Equivalency

2003
Exploratory aspirin resistance trial in healthy Japanese volunteers (J-ART) using platelet aggregation as a measure of thrombogenicity.
    The pharmacogenomics journal, 2007, Volume: 7, Issue:6

    Topics: Adult; Asian People; Aspirin; Drug Resistance; Gene Frequency; Genotype; Humans; Japan; Male; Membrane Glycoproteins; Membrane Proteins; Phenotype; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIb-IX Complex; Polymorphism, Single Nucleotide; Receptors, Thromboxane A2, Prostaglandin H2; Reference Values; Salicylic Acid; Thromboxane B2

2007
UGT1A6 polymorphism and salicylic acid glucuronidation following aspirin.
    Pharmacogenetics and genomics, 2007, Volume: 17, Issue:8

    Topics: Adult; Aspirin; Genotype; Glucuronides; Glucuronosyltransferase; Humans; Middle Aged; Pharmacogenetics; Polymorphism, Genetic; Salicylic Acid; Saliva

2007
Analytical determination and pharmacokinetics of major metabolites of carbasalate calcium in broilers following oral administration.
    Journal of veterinary pharmacology and therapeutics, 2011, Volume: 34, Issue:4

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chickens; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Administration Schedule; Female; Gentisates; Male; Salicylic Acid; Tandem Mass Spectrometry; Urea

2011
Simultaneous extraction of acetylsalicylic acid and salicylic acid from human plasma and simultaneous estimation by liquid chromatography and atmospheric pressure chemical ionization/tandem mass spectrometry detection. Application to a pharmacokinetic stu
    Arzneimittel-Forschung, 2011, Volume: 61, Issue:5

    Topics: Area Under Curve; Aspirin; Calibration; Chromatography, High Pressure Liquid; Cross-Over Studies; Drug Stability; Half-Life; Humans; Indicators and Reagents; Reference Standards; Reproducibility of Results; Salicylic Acid; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2011
Dissolution and pharmacokinetics of a novel micronized aspirin formulation.
    Inflammopharmacology, 2012, Volume: 20, Issue:4

    Topics: Adult; Aspirin; Chemistry, Pharmaceutical; Cross-Over Studies; Female; Humans; Male; Salicylic Acid; Solubility; Tablets

2012

Other Studies

450 other study(ies) available for salicylic acid and aspirin

ArticleYear
Novel analgesic-antiinflammatory salicylates.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Dogs; Rats; Salicylates; Structure-Activity Relationship

1978
Synthesis and analgesic-antiinflammatory activity of some 4- and 5-substituted heteroarylsalicylic acids.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry, Physical; Dogs; Edema; Gastrointestinal Hemorrhage; Rats; Salicylates

1978
Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes.
    Journal of medicinal chemistry, 1998, Mar-26, Volume: 41, Issue:7

    Topics: Absorption; Adsorption; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Permeability; Pharmacokinetics; Spectrophotometry, Ultraviolet

1998
Identification of multispecific organic anion transporter 2 expressed predominantly in the liver.
    FEBS letters, 1998, Jun-12, Volume: 429, Issue:2

    Topics: Animals; Blotting, Northern; Carrier Proteins; Ion Transport; Liver; Membrane Proteins; Organic Anion Transporters, Sodium-Independent; Rats; Salicylates; Salicylic Acid; Substrate Specificity; Xenopus laevis

1998
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes.
    Molecular pharmacology, 1999, Volume: 55, Issue:5

    Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis

1999
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Specific antioxidant activity of caffeoyl derivatives and other natural phenolic compounds: LDL protection against oxidation and decrease in the proinflammatory lysophosphatidylcholine production.
    Journal of natural products, 2001, Volume: 64, Issue:4

    Topics: Antioxidants; Caffeic Acids; Humans; Inflammation Mediators; Lipoproteins, LDL; Lysophosphatidylcholines; Oxidation-Reduction; Phenols

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
    International journal of pharmaceutics, 2003, Sep-16, Volume: 263, Issue:1-2

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport

2003
Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.
    The Journal of biological chemistry, 2007, Aug-17, Volume: 282, Issue:33

    Topics: Binding Sites; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Structure; Organic Anion Transport Protein 1; Organic Anion Transporters; Static Electricity; Substrate Specificity

2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Searching for new NO-donor aspirin-like molecules: a new class of nitrooxy-acyl derivatives of salicylic acid.
    Journal of medicinal chemistry, 2008, Mar-27, Volume: 51, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Aspirin; Carrageenan; Drug Evaluation, Preclinical; Edema; Humans; Hydrolysis; Male; Molecular Structure; Nitric Oxide Donors; Nitro Compounds; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Salicylic Acid; Solutions; Stereoisomerism; Vasodilator Agents; Water

2008
In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II.
    Bioorganic & medicinal chemistry, 2008, Oct-15, Volume: 16, Issue:20

    Topics: Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Cytosol; Humans; Inhibitory Concentration 50; Molecular Structure; Salicylic Acid; Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Synthesis and biological evaluation of nitrogen-containing chalcones as possible anti-inflammatory and antioxidant agents.
    Bioorganic & medicinal chemistry letters, 2010, Jan-15, Volume: 20, Issue:2

    Topics: Anti-Inflammatory Agents; Antioxidants; Chalcones; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Glucuronidase; Nitrogen; Trypsin; Trypsin Inhibitors

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney

2011
Searching for new NO-donor aspirin-like molecules: Furoxanylacyl derivatives of salicylic acid and related furazans.
    Bioorganic & medicinal chemistry, 2011, Oct-01, Volume: 19, Issue:19

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Collagen; Cyclooxygenase 1; Cyclooxygenase 2; Disease Models, Animal; Drug Stability; Edema; Humans; Hydrogen-Ion Concentration; Nitric Oxide Donors; Oxadiazoles; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Salicylic Acid; Vasodilator Agents

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
Structure-activity relationship of salicylic acid derivatives on inhibition of TNF-α dependent NFκB activity: Implication on anti-inflammatory effect of N-(5-chlorosalicyloyl)phenethylamine against experimental colitis.
    European journal of medicinal chemistry, 2012, Volume: 48

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Chemokine CXCL2; Colitis; HCT116 Cells; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Molecular Structure; NF-kappa B; Rats; Salicylates; Spectrophotometry, Infrared; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2012
Peroxisome proliferator-activated receptor-γ mediates the anti-inflammatory effect of 3-hydroxy-4-pyridinecarboxylic acid derivatives: synthesis and biological evaluation.
    European journal of medicinal chemistry, 2013, Volume: 62

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Dose-Response Relationship, Drug; Humans; Isonicotinic Acids; Lipopolysaccharides; Macrophages; Molecular Structure; PPAR gamma; RNA, Messenger; Structure-Activity Relationship; Transcription, Genetic

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Novel Resveratrol-Based Aspirin Prodrugs: Synthesis, Metabolism, and Anticancer Activity.
    Journal of medicinal chemistry, 2015, Aug-27, Volume: 58, Issue:16

    Topics: Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Aspirin; Caspase 3; Cell Cycle; Cell Line, Tumor; Cyclins; Enzyme Activation; Female; Humans; Intestinal Absorption; Mice; Mice, Inbred C57BL; Prodrugs; Resveratrol; Stilbenes

2015
Discovery of (2-aminophenyl)methanol as a new molecular chaperone that rescues the localization of P123S mutant pendrin stably expressed in HEK293 cells.
    Bioorganic & medicinal chemistry, 2017, 05-01, Volume: 25, Issue:9

    Topics: Amino Acid Substitution; Benzyl Alcohols; Cell Membrane; Goiter, Nodular; Hearing Loss, Sensorineural; HEK293 Cells; Humans; Membrane Transport Proteins; Microscopy, Fluorescence; Salicylates; Sulfate Transporters

2017
Discovery of the first Mycobacterium tuberculosis MabA (FabG1) inhibitors through a fragment-based screening.
    European journal of medicinal chemistry, 2020, Aug-15, Volume: 200

    Topics: Bacterial Proteins; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fatty Acid Synthases; Molecular Structure; Mycobacterium tuberculosis; ortho-Aminobenzoates; Structure-Activity Relationship

2020
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Modulation of leukocyte adhesion in rat mesenteric venules by aspirin and salicylate.
    Gastroenterology, 1992, Volume: 103, Issue:1

    Topics: Animals; Aspirin; Cell Adhesion; Cell Movement; Leukocytes; Leukotriene B4; Male; Platelet Activating Factor; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Splanchnic Circulation; Venules

1992
Effects of aspirin on pathways of ion permeation in Necturus antrum: role of nutrient HCO3.
    Gastroenterology, 1992, Volume: 103, Issue:5

    Topics: Acetates; Acetic Acid; Animals; Aspirin; Bicarbonates; Biological Transport; Cell Membrane; Gastric Mucosa; Hydrogen-Ion Concentration; In Vitro Techniques; Membrane Potentials; Microscopy, Electron; Necturus; Pyloric Antrum; Salicylates; Salicylic Acid; Water-Electrolyte Balance

1992
Aspirin, acetaminophen and proton transport through phospholipid bilayers and mitochondrial membranes.
    Molecular and cellular biochemistry, 1992, Sep-08, Volume: 114, Issue:1-2

    Topics: Acetaminophen; Animals; Anions; Aspirin; Biological Transport; Humans; Hydrogen-Ion Concentration; Intracellular Membranes; Lipid Bilayers; Mitochondria; Oxidative Phosphorylation; Permeability; Phospholipids; Protons; Reye Syndrome; Salicylates; Salicylic Acid; Uncoupling Agents

1992
Determination of salicylic acid by HPLC in plasma and saliva from children with juvenile chronic arthritis.
    The Tokai journal of experimental and clinical medicine, 1992, Volume: 17, Issue:5-6

    Topics: Adolescent; Arthritis, Juvenile; Aspirin; Child; Chromatography, High Pressure Liquid; Female; Humans; Male; Salicylates; Salicylic Acid; Saliva

1992
The presence of specific IgE to salicyloyl and O-methylsalicyloyl in aspirin-sensitive patients.
    Asian Pacific journal of allergy and immunology, 1992, Volume: 10, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aspirin; Drug Hypersensitivity; Female; Humans; Immunoglobulin E; Male; Middle Aged; Radioallergosorbent Test; Salicylates; Salicylic Acid

1992
The effect of antacid on aspirin pharmacokinetics in healthy Thai volunteers.
    Drug metabolism and drug interactions, 1992, Volume: 10, Issue:3

    Topics: Adult; Aluminum Hydroxide; Aspirin; Biological Availability; Chromatography, High Pressure Liquid; Drug Interactions; Female; Hippurates; Humans; Magnesium Hydroxide; Male; Salicylates; Salicylic Acid; Thailand

1992
Simultaneous spectrophotometric determination in solid phase of aspirin and its impurity salicylic acid in pharmaceutical formulations.
    Journal of pharmaceutical sciences, 1992, Volume: 81, Issue:9

    Topics: Aspirin; Drug Contamination; Salicylates; Salicylic Acid; Spectrophotometry

1992
Bioavailability of two formulations of acetylsalicylic acid gums.
    Die Pharmazie, 1992, Volume: 47, Issue:8

    Topics: Adult; Aspirin; Biological Availability; Chewing Gum; Humans; Male; Salicylates; Salicylic Acid

1992
Simultaneous high-performance liquid chromatographic determination of salicylates in whole blood, plasma and isolated erythrocytes.
    Journal of chromatography, 1992, Dec-23, Volume: 584, Issue:2

    Topics: Animals; Aspirin; Cells, Cultured; Chromatography, High Pressure Liquid; Erythrocytes; Gentisates; Hippurates; Hydroxybenzoates; Rabbits; Reproducibility of Results; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet

1992
Evaluation of 2-(2-thiophenecarboxy)benzoic acid and related active metabolites in biological samples.
    Journal of chromatography, 1992, Jan-03, Volume: 573, Issue:1

    Topics: Animals; Aspirin; Benzoates; Chromatography, Liquid; Female; Hydrogen-Ion Concentration; Male; Naproxen; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet; Thiophenes; Tissue Distribution

1992
Intrathecal injection of acetylsalicylic acid, salicylic acid and indomethacin depresses C fibre-evoked activity in the rat thalamus and spinal cord.
    Pain, 1992, Volume: 49, Issue:2

    Topics: Afferent Pathways; Animals; Aspirin; Axons; Behavior, Animal; Female; Indomethacin; Injections, Spinal; Male; Nerve Fibers; Neurons; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Spinal Cord; Thalamus

1992
Disposition of single-dose intravenous and oral aspirin in children.
    Developmental pharmacology and therapeutics, 1991, Volume: 17, Issue:3-4

    Topics: Absorption; Administration, Oral; Aspirin; Biological Availability; Buffers; Child, Preschool; Drug Administration Schedule; Half-Life; Humans; Infusions, Intravenous; Mucocutaneous Lymph Node Syndrome; Salicylates; Salicylic Acid

1991
Simultaneous determination of acetylsalicylic and salicylic acids in human serum and aspirin formulations by second-derivative synchronous fluorescence spectrometry.
    The Analyst, 1991, Volume: 116, Issue:4

    Topics: Aspirin; Humans; Salicylates; Salicylic Acid; Spectrometry, Fluorescence

1991
Misoprostol does not protect articular cartilage from salicylate-induced suppression of proteoglycan synthesis.
    Journal of clinical pharmacology, 1991, Volume: 31, Issue:7

    Topics: Alprostadil; Animals; Aspirin; Cartilage, Articular; Cells, Cultured; Culture Media; Dogs; Glycosaminoglycans; Humerus; Misoprostol; Salicylates; Salicylic Acid; Sodium Salicylate

1991
[Pharmacokinetics of acetylsalicylic acid for the prophylaxis of cardiovascular pathology].
    Medicina clinica, 1991, May-11, Volume: 96, Issue:18

    Topics: Adult; Aspirin; Cardiovascular Diseases; Delayed-Action Preparations; Female; Humans; Male; Salicylates; Salicylic Acid; Tablets, Enteric-Coated

1991
Topical irritation of the gastrointestinal tract.
    Pharmaceutical research, 1990, Volume: 7, Issue:12

    Topics: Animals; Aspirin; Colon; Rabbits; Salicylates; Salicylic Acid

1990
Do salicylates and ascorbate increase the outer membrane permeability to hydrophobic antibiotics in Pseudomonas aeruginosa?
    Drugs under experimental and clinical research, 1990, Volume: 16, Issue:11

    Topics: Ascorbic Acid; Aspirin; Cell Membrane Permeability; Deoxycholic Acid; Fusidic Acid; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Rifampin; Salicylates; Salicylic Acid

1990
Effects of non-steroidal anti-inflammatory drugs on human neutrophil NADPH oxidase in both whole cell and cell-free systems.
    Biochemical pharmacology, 1990, Aug-01, Volume: 40, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell-Free System; Enzyme Activation; Humans; Indomethacin; Kinetics; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Salicylates; Salicylic Acid; Superoxides; Tetradecanoylphorbol Acetate

1990
Aspirin potentiates prestimulated acid secretion and mobilizes intracellular calcium in rabbit parietal cells.
    The Journal of clinical investigation, 1990, Volume: 86, Issue:2

    Topics: Adenosine Triphosphatases; Aminopyrine; Animals; Aspirin; Biological Transport; Calcium; Cyclic AMP; Dinoprostone; Gastric Juice; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Inositol Phosphates; Rabbits; Receptors, Cell Surface; Salicylates; Salicylic Acid; Signal Transduction

1990
Comparative metabolism of high doses of aspirin in man and rat.
    Xenobiotica; the fate of foreign compounds in biological systems, 1990, Volume: 20, Issue:8

    Topics: Adolescent; Adult; Animals; Aspirin; Female; Gentisates; Glucuronates; Hippurates; Humans; Kinetics; Male; Middle Aged; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid

1990
Determination of salicilic acid in saliva by high-performance liquid chromatography.
    Farmaco (Societa chimica italiana : 1989), 1990, Volume: 45, Issue:6

    Topics: Aspirin; Biological Availability; Chromatography, High Pressure Liquid; Humans; Salicylates; Salicylic Acid; Saliva

1990
Depletion of plasma glycine and effect of glycine by mouth on salicylate metabolism during aspirin overdose.
    Human & experimental toxicology, 1990, Volume: 9, Issue:6

    Topics: Administration, Oral; Adult; Aged; Aspirin; Drug Overdose; Female; Glycine; Glycylglycine; Hippurates; Humans; Male; Middle Aged; Salicylates; Salicylic Acid

1990
Repeated oral administration of activated charcoal for treating aspirin overdose in young children.
    Pediatrics, 1990, Volume: 85, Issue:4

    Topics: Administration, Oral; Aspirin; Charcoal; Dialysis; Half-Life; Humans; Infant; Magnesium Sulfate; Male; Salicylates; Salicylic Acid

1990
Metabolism of aspirin after therapeutic and toxic doses.
    Human & experimental toxicology, 1990, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Aspirin; Child; Dose-Response Relationship, Drug; Female; Hippurates; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Salicylates; Salicylic Acid

1990
Nondestructive near-infrared analysis of intact tablets for determination of degradation products.
    Journal of pharmaceutical sciences, 1990, Volume: 79, Issue:7

    Topics: Aspirin; Chromatography, High Pressure Liquid; Mathematics; Salicylates; Salicylic Acid; Spectrophotometry, Infrared; Tablets

1990
Time-course of aspirin and salicylate in ocular tissues of rabbits.
    Lens and eye toxicity research, 1989, Volume: 6, Issue:3

    Topics: Animals; Aqueous Humor; Aspirin; Ciliary Body; Cornea; Eye; Half-Life; Injections, Intravenous; Iris; Lens, Crystalline; Male; Rabbits; Retina; Salicylates; Salicylic Acid; Tissue Distribution; Vitreous Body

1989
Renal handling of aspirin in the rat.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:1

    Topics: Animals; Aspirin; In Vitro Techniques; Kidney; Male; Perfusion; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid

1989
Pharmacokinetics of salicylic acid following administration of aspirin tablets and three different forms of soluble aspirin in normal subjects.
    International journal of clinical pharmacology research, 1989, Volume: 9, Issue:6

    Topics: Adult; Aspirin; Buffers; Humans; Lysine; Salicylates; Salicylic Acid; Solubility; Tablets

1989
Prevention of aspirin-induced gastric mucosal injury by histamine H2 receptor antagonists: a crossover endoscopic and intragastric pH study in the dog.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:3

    Topics: Animals; Aspirin; Dogs; Female; Gastric Acid; Gastric Acidity Determination; Gastric Mucosa; Gastroscopy; Histamine H2 Antagonists; Male; Salicylates; Salicylic Acid

1987
Effects of aspirin, indomethacin, and sodium salicylate on human erythrocyte membranes as detected with electron spin resonance spectroscopy.
    Thrombosis research, 1985, Dec-15, Volume: 40, Issue:6

    Topics: Aspirin; Blood Coagulation; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Female; Humans; Indomethacin; Kinetics; Male; Membrane Fluidity; Salicylates; Salicylic Acid; Sex Factors; Thermodynamics

1985
Effect of triflusal and other salicylic acid derivatives on cyclic AMP levels in rat platelets.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 284, Issue:1

    Topics: Alprostadil; Animals; Aspirin; Blood Platelets; Cyclic AMP; Dipyridamole; Drug Interactions; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid

1986
Oxidation of salicylates by stimulated granulocytes: evidence that these drugs act as free radical scavengers in biological systems.
    Journal of immunology (Baltimore, Md. : 1950), 1987, Apr-01, Volume: 138, Issue:7

    Topics: Aspirin; Benzoates; Benzoic Acid; Chloramines; Free Radicals; Granulocytes; Hydrogen Peroxide; Hydroxides; Hypochlorous Acid; Oxidation-Reduction; Salicylates; Salicylic Acid; Superoxides; Thiourea; Xanthine Oxidase; Xanthines

1987
Role of lipoxygenase metabolism in platelet function: effect of aspirin and salicylate.
    Prostaglandins, leukotrienes, and medicine, 1986, Volume: 21, Issue:2

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Aspirin; Blood Platelets; Collagen; Humans; Hydroxyeicosatetraenoic Acids; Lipoxygenase; Platelet Adhesiveness; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Salicylates; Salicylic Acid; Thromboxane B2

1986
Two modes of analgesic action of aspirin, and the site of analgesic action of salicylic acid.
    International journal of tissue reactions, 1986, Volume: 8, Issue:4

    Topics: Analgesia; Animals; Aspirin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Inflammation; Male; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid

1986
Heterogeneity of changes on the disposition of aspirin in rats with CCl4-induced chronic liver damage.
    Biochemical pharmacology, 1987, Sep-15, Volume: 36, Issue:18

    Topics: Aniline Hydroxylase; Animals; Aspirin; Carbon Tetrachloride; Carboxylic Ester Hydrolases; Colchicine; Gentisates; Glucuronates; Glucuronosyltransferase; Hydroxybenzoates; Kinetics; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid

1987
Platelets, eicosanoids, and coronary vasospasm.
    Progress in clinical and biological research, 1987, Volume: 242

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cattle; Coronary Vasospasm; Coronary Vessels; Eicosanoic Acids; Humans; In Vitro Techniques; Methysergide; Muscle, Smooth, Vascular; Prostaglandin Endoperoxides, Synthetic; Salicylates; Salicylic Acid; Vasoconstriction

1987
Effects and interaction studies of triflusal and other salicylic derivatives on cyclooxygenase in rats.
    Prostaglandins, leukotrienes, and essential fatty acids, 1988, Volume: 31, Issue:2

    Topics: Alprostadil; Animals; Aorta, Thoracic; Aspirin; Blood Platelets; Drug Interactions; In Vitro Techniques; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Vasodilator Agents

1988
Selectivity of oral aspirin as an inhibitor of platelet vs. vascular cyclooxygenase activity is reduced by portacaval shunt in rats.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Animals; Aspirin; Blood Platelets; Blood Vessels; Cyclooxygenase Inhibitors; Gastric Mucosa; Liver; Male; Portacaval Shunt, Surgical; Rats; Salicylates; Salicylic Acid; Thromboxane B2; Time Factors

1988
Effects of salicylate vs. aspirin on renal prostaglandins and function in normal and sodium-depleted dogs.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:1

    Topics: Animals; Aspirin; Blood Pressure; Diet, Sodium-Restricted; Dogs; Female; Glomerular Filtration Rate; Kidney; Male; Meclofenamic Acid; Potassium; Prostaglandins; Renal Circulation; Salicylates; Salicylic Acid

1988
Pharmacokinetics of low-dose oral modified release, soluble and intravenous aspirin in man, and effects on platelet function.
    European journal of clinical pharmacology, 1988, Volume: 35, Issue:3

    Topics: Administration, Oral; Adult; Aspirin; Female; Humans; Injections, Intravenous; Kinetics; Male; Middle Aged; Platelet Aggregation; Salicylates; Salicylic Acid; Thromboxane A2

1988
The effect of concurrent aspirin upon plasma concentrations of tenoxicam.
    British journal of clinical pharmacology, 1988, Volume: 26, Issue:4

    Topics: Adult; Aspirin; Drug Interactions; Female; Humans; Male; Piroxicam; Protein Binding; Salicylates; Salicylic Acid

1988
Effect of intragastric pH on mucosal protective action of sucralfate.
    Gut, 1988, Volume: 29, Issue:10

    Topics: Animals; Aspirin; Bile Acids and Salts; Gastric Mucosa; Hydrogen-Ion Concentration; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Sucralfate

1988
Pharmacokinetics of enteric-coated aspirin and inhibition of platelet thromboxane A2 and vascular prostacyclin generation in humans.
    Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:2

    Topics: Adult; Aspirin; Blood Platelets; Epoprostenol; Female; Humans; Kinetics; Salicylates; Salicylic Acid; Saphenous Vein; Tablets, Enteric-Coated; Thromboxane A2; Thromboxane B2

1987
[Which of the various acetylsalicylic acid preparations is the most appropriate in each indication? A pharmacokinetic study].
    Medicina clinica, 1988, Feb-20, Volume: 90, Issue:7

    Topics: Adult; Aspirin; Chromatography, High Pressure Liquid; Drug Evaluation; Female; Humans; Male; Salicylates; Salicylic Acid; Time Factors

1988
Molecular integrity of aspirin in relation to Reye's syndrome.
    The West Virginia medical journal, 1988, Volume: 84, Issue:5

    Topics: Adolescent; Aspirin; Child; Child, Preschool; Humans; Hydrogen-Ion Concentration; Hydrolysis; Infant; Research; Reye Syndrome; Salicylates; Salicylic Acid; Spectrophotometry

1988
Nonlinear pharmacokinetics of aspirin in rats.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:3

    Topics: Animals; Aspirin; Biological Availability; Dose-Response Relationship, Drug; Liver; Male; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid

1988
Effects of administration route on pharmacokinetics of aspirin in the rabbit.
    Methods and findings in experimental and clinical pharmacology, 1988, Volume: 10, Issue:3

    Topics: Animals; Aspirin; Infusions, Parenteral; Injections, Intravenous; Male; Rabbits; Salicylates; Salicylic Acid

1988
The absorption of acetylsalicylic acid from an enteric-coated formulation and the inhibition of thromboxane formation.
    International journal of clinical pharmacology, therapy, and toxicology, 1988, Volume: 26, Issue:2

    Topics: Adult; Aspirin; Depression, Chemical; Female; Half-Life; Humans; Intestinal Absorption; Male; Salicylates; Salicylic Acid; Tablets; Tablets, Enteric-Coated; Thromboxane B2; Thromboxanes

1988
Effect of triflusal and acetylsalicylic acid on platelet aggregation in human whole blood: influence of red blood cells and leukocytes.
    Methods and findings in experimental and clinical pharmacology, 1988, Volume: 10, Issue:6

    Topics: Adult; Aspirin; Erythrocytes; Humans; In Vitro Techniques; Leukocytes; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Salicylates; Salicylic Acid

1988
Inhibition by salicylates of urea synthesis by isolated rat hepatocytes and citrulline synthesis by isolated rat mitochondria: an effect independent of uncoupling.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1988, Volume: 20, Issue:6

    Topics: Animals; Aspirin; Citrulline; Liver; Male; Mitochondria, Liver; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Urea

1988
Prostaglandin E2 binding sites in porcine oxyntic mucosa: effects of salicylates.
    Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:5

    Topics: Animals; Aspirin; Binding Sites; Dinoprostone; Female; Gastric Mucosa; Parietal Cells, Gastric; Prostaglandins E; Salicylates; Salicylic Acid; Swine; Tritium

1986
An in situ experimental model in rabbits for the study of rectal absorption.
    Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:2

    Topics: Animals; Aspirin; Indomethacin; Insulin; Intestinal Absorption; Kinetics; Male; Rabbits; Rectum; Salicylates; Salicylic Acid; Suppositories; Time Factors

1986
Lowering of plasma isoxicam concentrations with acetylsalicylic acid.
    The Journal of rheumatology, 1986, Volume: 13, Issue:6

    Topics: Administration, Oral; Adult; Aged; Aspirin; Binding, Competitive; Drug Interactions; Humans; Kinetics; Male; Middle Aged; Piroxicam; Protein Binding; Salicylates; Salicylic Acid

1986
Effect of clofibrate on lipid peroxidation in rats treated with aspirin and 4-pentenoic acid.
    Journal of biochemistry, 1987, Volume: 101, Issue:1

    Topics: Animals; Aspirin; Clofibrate; Cytosol; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Lipid Metabolism; Lipid Peroxides; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Proteins; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Sulfhydryl Compounds

1987
Salicyl phenolic glucuronide pharmacokinetics in patients with rheumatoid arthritis.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:2

    Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Female; Glucuronates; Humans; Kinetics; Male; Middle Aged; Salicylates; Salicylic Acid

1987
The evolution of non-steroidal anti-inflammatory drugs and their mechanisms of action.
    Drugs, 1987, Volume: 33 Suppl 1

    Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Humans; Inflammation; Salicylates; Salicylic Acid

1987
Determination of aspirin and salicylic acid in uremic patients' plasma using reversed-phase high-performance liquid chromatography.
    Therapeutic drug monitoring, 1987, Volume: 9, Issue:2

    Topics: Aspirin; Chromatography, High Pressure Liquid; Humans; Salicylates; Salicylic Acid; Uremia

1987
Comparison of the effect of acetylsalicylic acid on platelet function in male and female patients with ischemic stroke.
    Thrombosis research, 1987, Aug-01, Volume: 47, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Aged; Aspirin; Blood Platelets; Brain Ischemia; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Aggregation; Salicylates; Salicylic Acid; Sex Factors; Thromboxane B2

1987
Serum salicylate levels in a breast fed infant.
    Annals of the rheumatic diseases, 1987, Volume: 46, Issue:8

    Topics: Adult; Arthritis, Juvenile; Aspirin; Breast Feeding; Female; Humans; Infant; Milk, Human; Pregnancy; Salicylates; Salicylic Acid

1987
Inhibition of platelet 5-HT secretion and of 5-HT induced vasoconstriction by paracetamol.
    Progress in clinical and biological research, 1987, Volume: 242

    Topics: Acetaminophen; Adenosine Diphosphate; Aspirin; Blood Platelets; Humans; In Vitro Techniques; Platelet Aggregation; Salicylates; Salicylic Acid; Serotonin; Thromboxane A2; Vasoconstriction

1987
Disposition of aspirin and its metabolites in the semen of man.
    Journal of clinical pharmacology, 1987, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Aspirin; Hippurates; Humans; Male; Salicylates; Salicylic Acid; Semen

1987
Determination of plasma aspirin and salicylic acid concentrations after low aspirin doses by high-performance liquid chromatography with post-column hydrolysis and fluorescence detection.
    Journal of chromatography, 1987, Sep-25, Volume: 420, Issue:2

    Topics: Aspirin; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Humans; Hydrogen-Ion Concentration; Hydrolysis; Salicylates; Salicylic Acid; Spectrometry, Fluorescence

1987
Studies of platelet hyperactivity in patients with ischemic cerebrovascular diseases: IV. Determination of the optimal dosage of aspirin by measuring plasma salicylate level.
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1987, Volume: 86, Issue:9

    Topics: Aged; Aspirin; Blood Platelets; Brain Ischemia; Female; Humans; Male; Middle Aged; Salicylates; Salicylic Acid; Thromboxane B2

1987
The metabolism of aspirin in man: a population study.
    Xenobiotica; the fate of foreign compounds in biological systems, 1986, Volume: 16, Issue:3

    Topics: Adult; Aspirin; Biotransformation; Female; Glucuronates; Glycine; Hippurates; Humans; Hydrogen-Ion Concentration; Male; Salicylates; Salicylic Acid; Sex Factors

1986
Mechanisms of cell association of chloroquine to leucocytes.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:1

    Topics: Aspirin; Cell Survival; Chloroquine; Humans; Hydrogen-Ion Concentration; Indomethacin; Leukocytes; Mathematics; Neutrophils; Salicylates; Salicylic Acid; Temperature; Time Factors

1986
Application of a radiotelemetric system to evaluate the performance of enteric coated and plain aspirin tablets.
    Journal of pharmaceutical sciences, 1986, Volume: 75, Issue:5

    Topics: Animals; Aspirin; Biological Availability; Blood Specimen Collection; Dogs; Injections, Intravenous; Kinetics; Male; Salicylates; Salicylic Acid; Tablets; Tablets, Enteric-Coated; Telemetry

1986
Influence of age, gender, and obesity on salicylate kinetics following single doses of aspirin.
    Arthritis and rheumatism, 1986, Volume: 29, Issue:8

    Topics: Administration, Oral; Adult; Age Factors; Aged; Aspirin; Body Weight; Female; Humans; Infusions, Parenteral; Kinetics; Male; Obesity; Salicylates; Salicylic Acid; Sex Factors

1986
Influence of gender and oral contraceptive steroids on the metabolism of salicylic acid and acetylsalicylic acid.
    British journal of clinical pharmacology, 1986, Volume: 22, Issue:2

    Topics: Adult; Aspirin; Blood Proteins; Contraceptives, Oral, Hormonal; Female; Humans; Kinetics; Male; Protein Binding; Salicylates; Salicylic Acid; Sex Factors

1986
Toxic interaction between acetazolamide and salicylate: case reports and a pharmacokinetic explanation.
    Clinical pharmacology and therapeutics, 1986, Volume: 40, Issue:5

    Topics: Acetazolamide; Aged; Aged, 80 and over; Aspirin; Blood Proteins; Drug Interactions; Female; Humans; Kinetics; Male; Metabolic Clearance Rate; Protein Binding; Salicylates; Salicylic Acid

1986
Salicylates and 12-lipoxygenase activity in human washed platelets.
    Pharmacological research communications, 1986, Volume: 18, Issue:11

    Topics: Adult; Arachidonate 12-Lipoxygenase; Arachidonate Lipoxygenases; Aspirin; Blood Platelets; Chromatography, High Pressure Liquid; Gentisates; Humans; Hydroxybenzoates; In Vitro Techniques; Lipoxygenase Inhibitors; Salicylamides; Salicylates; Salicylic Acid

1986
Effect of food on the absorption of enteric-coated aspirin: correlation with gastric residence time.
    Clinical pharmacology and therapeutics, 1987, Volume: 41, Issue:1

    Topics: Absorption; Adult; Aspirin; Eating; Fasting; Female; Gastric Emptying; Hippurates; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Salicylates; Salicylic Acid; Tablets, Enteric-Coated

1987
Differential salicylate-aspirin interaction on vascular prostacyclin and platelet thromboxane synthesis in patients undergoing saphenectomy.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 180, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aspirin; Blood Platelets; Drug Interactions; Female; Humans; Middle Aged; Salicylates; Salicylic Acid; Thromboxane B2; Varicose Veins; Veins

1985
Salicylate antagonizes the antiinflammatory action of aspirin in the rat.
    Prostaglandins, leukotrienes, and medicine, 1985, Volume: 20, Issue:1

    Topics: Animals; Aspirin; Carrageenan; Drug Antagonism; Edema; Kinetics; Male; Rats; Salicylates; Salicylic Acid

1985
Differences in the haemorrhagic toxicity of aspirin between rats and mice.
    Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:1

    Topics: Animals; Aspirin; Dose-Response Relationship, Drug; Gastrointestinal Hemorrhage; Gentisates; Hydroxybenzoates; Kaolin; Liver; Male; Mice; Mice, Inbred ICR; Organ Size; Partial Thromboplastin Time; Prothrombin Time; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Species Specificity; Time Factors

1985
Acute effects of acetylsalicylic acid on renal and hepatic function in normal humans.
    International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Alanine Transaminase; Albuminuria; Aspartate Aminotransferases; Aspirin; beta 2-Microglobulin; Female; Humans; Kidney; Liver; Male; Middle Aged; Proteinuria; Prothrombin Time; Salicylates; Salicylic Acid

1985
Indomethacin and salicylate modulate effect of insulin on glucose kinetics in dogs.
    The American journal of physiology, 1985, Volume: 248, Issue:6 Pt 1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Glucose; Dogs; Drug Interactions; Female; Gluconeogenesis; Glucose; Indomethacin; Insulin; Kinetics; Liver; Prostaglandin Antagonists; Prostaglandins; Salicylates; Salicylic Acid; Time Factors

1985
Cyclooxygenase inhibitors affect Met-enkephalin- and acetylcholine-stimulated motility of the isolated rat colon.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:3

    Topics: Acetylcholine; Animals; Aspirin; Colon; Cyclooxygenase Inhibitors; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Dose-Response Relationship, Drug; Enkephalin, Methionine; Gastrointestinal Motility; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid

1985
Endothelial cells produce a lipoxygenase derived chemo-repellent which influences platelet/endothelial cell interactions--effect of aspirin and salicylate.
    Thrombosis and haemostasis, 1985, Jun-24, Volume: 53, Issue:3

    Topics: Adenine; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cell Adhesion; Cells, Cultured; Endothelium; Female; Humans; Kinetics; Lipoxygenase; Phospholipids; Platelet Adhesiveness; Pregnancy; Prostaglandin-Endoperoxide Synthases; Salicylates; Salicylic Acid; Umbilical Veins

1985
Gastric ulcer formation and cyclo-oxygenase inhibition in cat antrum follows parenteral administration of aspirin but not salicylate.
    European journal of pharmacology, 1985, Oct-08, Volume: 116, Issue:1-2

    Topics: Animals; Aspirin; Cats; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Female; Histamine; Infusions, Parenteral; Male; Prostaglandins E; Salicylates; Salicylic Acid; Stomach Ulcer

1985
Interaction of non-steroidal anti-inflammatory drugs on platelet cyclo-oxygenase and lipoxygenase activity.
    International journal of tissue reactions, 1985, Volume: 7, Issue:4

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Humans; Indomethacin; Kinetics; Lipoxygenase; Models, Biological; Prostaglandin-Endoperoxide Synthases; Salicylates; Salicylic Acid; Sulfinpyrazone

1985
Bioavailability of sustained-release aspirin preparations.
    Clinical pharmacy, 1986, Volume: 5, Issue:3

    Topics: Adult; Aspirin; Biological Availability; Delayed-Action Preparations; Humans; Male; Salicylates; Salicylic Acid; Time Factors

1986
Plasma and synovial fluid concentrations of salicylic acid and its metabolites in patients with joint effusions.
    The Journal of rheumatology, 1985, Volume: 12, Issue:1

    Topics: Adult; Aged; Arthritis; Aspirin; Female; Gentisates; Hippurates; Humans; Hydroxybenzoates; Male; Middle Aged; Salicylates; Salicylic Acid; Synovial Fluid

1985
Confirmation of serum salicylate levels in Reye's syndrome: a comparison between the Natelson colorimetric method and high performance liquid chromatography.
    Clinica chimica acta; international journal of clinical chemistry, 1985, Feb-15, Volume: 145, Issue:3

    Topics: Ammonia; Aspirin; Child; Chromatography, High Pressure Liquid; Colorimetry; Humans; Reye Syndrome; Salicylates; Salicylic Acid

1985
Plasma salicylate levels and platelet function after acute and chronic administration of slow-release acetylsalicylic acid (Monobeltin).
    European journal of clinical pharmacology, 1985, Volume: 27, Issue:6

    Topics: Adult; Aspirin; Blood Platelets; Delayed-Action Preparations; Hippurates; Humans; Male; Platelet Aggregation; Salicylates; Salicylic Acid; Time Factors

1985
Inhibition of human platelet thromboxane generation by aspirin in the absence of measurable drug levels in peripheral blood.
    Biochemical pharmacology, 1985, May-15, Volume: 34, Issue:10

    Topics: Adult; Aspirin; Blood Platelets; Depression, Chemical; Humans; Male; Salicylates; Salicylic Acid; Thromboxanes

1985
The effects of age and sex on the disposition of acetylsalicylic acid and its metabolites.
    British journal of clinical pharmacology, 1985, Volume: 19, Issue:5

    Topics: Adult; Age Factors; Aged; Aspirin; Biotransformation; Female; Hippurates; Humans; Male; Models, Biological; Salicylates; Salicylic Acid; Sex Factors

1985
High-pressure liquid chromatographic analysis of paracetamol, caffeine and acetylsalicylic acid in tablets. Salicylic acid quantitation.
    Il Farmaco; edizione pratica, 1985, Volume: 40, Issue:4

    Topics: Acetaminophen; Aspirin; Caffeine; Chromatography, High Pressure Liquid; Salicylates; Salicylic Acid; Tablets

1985
Determination of paracetamol, salicylic acid and acetyl salicylic acid in serum by high-performance liquid chromatography.
    Journal of chromatography, 1985, Jul-05, Volume: 329, Issue:1

    Topics: Acetaminophen; Aspirin; Chromatography, High Pressure Liquid; Humans; Salicylates; Salicylic Acid

1985
A sensitive liquid chromatographic assay for plasma aspirin and salicylate concentrations after low doses of aspirin.
    Therapeutic drug monitoring, 1985, Volume: 7, Issue:2

    Topics: Adult; Aspirin; Chromatography, Liquid; Female; Humans; Kinetics; Male; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet

1985
[The bioavailability of combination preparations of acetylsalicylic acid and codeine phosphate].
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:6

    Topics: Administration, Oral; Adult; Aspirin; Biological Availability; Codeine; Drug Combinations; Hippurates; Humans; Injections, Intravenous; Kinetics; Salicylates; Salicylic Acid; Suppositories

1985
Decomposition of aspirin in the solid state in the presence of limited amounts of moisture.
    Journal of pharmaceutical sciences, 1985, Volume: 74, Issue:7

    Topics: Acetates; Aspirin; Drug Stability; Humidity; Kinetics; Salicylates; Salicylic Acid; Solubility; Temperature; Time Factors; Water

1985
Aspirin dosing using 15 grain enteric coated tablets.
    The Journal of rheumatology, 1985, Volume: 12, Issue:2

    Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Osteoarthritis; Salicylates; Salicylic Acid; Tablets, Enteric-Coated; Tinnitus

1985
[Reaction kinetics of the dissolution of acetylsalicylic acid and salicylic acid in aqueous solution. I. pH and temperature dependence of salicylic acid decomposition].
    Acta pharmaceutica Hungarica, 1985, Volume: 55, Issue:3

    Topics: Aspirin; Chemical Phenomena; Chemistry; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Salicylates; Salicylic Acid; Solubility; Thermodynamics

1985
Aspirin kinetics and inhibition of platelet thromboxane generation-relevance for a solution of the "aspirin dilemma".
    Thrombosis and haemostasis, 1985, Jun-24, Volume: 53, Issue:3

    Topics: Adult; Aspirin; Blood Platelets; Capsules; Humans; Kinetics; Male; Salicylates; Salicylic Acid; Tablets; Thromboxane B2

1985
Effect of antacids on salicylate kinetics.
    International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:9

    Topics: Adult; Aluminum Hydroxide; Antacids; Aspirin; Drug Combinations; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Kinetics; Magnesium Hydroxide; Male; Salicylates; Salicylic Acid; Silicic Acid

1985
The effect of ionization on partition coefficients and topical delivery.
    Acta pharmaceutica Suecica, 1985, Volume: 22, Issue:4

    Topics: Administration, Topical; Animals; Aspirin; Male; Mice; Mice, Hairless; Salicylates; Salicylic Acid; Solubility

1985
Attenuation of aspirin analgesia by calcium loading in healthy subjects.
    Journal of pharmacobio-dynamics, 1985, Volume: 8, Issue:7

    Topics: Adult; Analgesics; Aspirin; Calcium; Humans; Magnesium; Male; Phosphates; Salicylates; Salicylic Acid

1985
Clinical-pharmacokinetic investigations of acetylsalicylic acid in cases of imminent premature delivery.
    Journal of clinical and hospital pharmacy, 1985, Volume: 10, Issue:4

    Topics: Amniotic Fluid; Aspirin; Female; Fetal Blood; Humans; Infant, Newborn; Kinetics; Obstetric Labor, Premature; Placenta; Pregnancy; Salicylates; Salicylic Acid; Time Factors

1985
Salicylate inhibition of antiplatelet effect of aspirin.
    Lancet (London, England), 1981, Dec-12, Volume: 2, Issue:8259

    Topics: Aspirin; Diflunisal; Humans; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Salicylates; Salicylic Acid

1981
Bioavailability of magnesium salicylate.
    The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:12

    Topics: Absorption; Animals; Aspirin; Biological Availability; Dogs; Female; Salicylates; Salicylic Acid

1981
Determination of salicylic acid in acetylsalicylic acid by second derivative u.v.-spectrophotometry.
    The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:7

    Topics: Aspirin; Dioxanes; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet

1982
Absorption of acetylsalicylic acid from enteric-coated tablets in relation to gastric emptying and in-vivo disintegration.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:5

    Topics: Aspirin; Gastric Emptying; Humans; Intestinal Absorption; Salicylates; Salicylic Acid; Solubility; Tablets, Enteric-Coated

1984
Theophylline, dyphylline, caffeine, acetaminophen, salicylate, acetylsalicylate, procainamide, and N-acetylprocainamide determined in serum with a single liquid-chromatographic assay.
    Clinical chemistry, 1982, Volume: 28, Issue:10

    Topics: Acecainide; Acetaminophen; Aspirin; Caffeine; Chromatography, High Pressure Liquid; Dyphylline; Humans; Pharmaceutical Preparations; Procainamide; Salicylates; Salicylic Acid; Theophylline

1982
Failure of salicylate to reduce inhibition of human venous prostacyclin in synthesis by conventional dose aspirin.
    Thrombosis and haemostasis, 1983, Feb-28, Volume: 49, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Aspirin; Epoprostenol; Humans; Kinetics; Prostaglandins; Salicylates; Salicylic Acid; Veins

1983
Selective mitochondrial activity distinguishes aspirin from salicylate and benzoate in yeast cells.
    Biochemical pharmacology, 1983, Jul-01, Volume: 32, Issue:13

    Topics: Aspirin; Benzoates; Benzoic Acid; Mitochondria; Mutation; Oxygen Consumption; Saccharomyces cerevisiae; Salicylates; Salicylic Acid

1983
Effect of salicylates on intestinal secretion in calves given (intestinal loops) Escherichia coli heat-stable enterotoxin.
    American journal of veterinary research, 1983, Volume: 44, Issue:12

    Topics: Animals; Aspirin; Cattle; Cattle Diseases; Diarrhea; Enterotoxins; Escherichia coli; Intestinal Secretions; Male; Mice; Osmolar Concentration; Salicylates; Salicylic Acid

1983
Salicylate fails to prevent the inhibitory effect of 5,8,11,14-eicosatetraynoic acid on human platelet cyclo-oxygenase and lipoxygenase activities.
    Biochimica et biophysica acta, 1983, Aug-23, Volume: 759, Issue:1-2

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Aspirin; Blood Platelets; Fatty Acids, Unsaturated; Humans; Indomethacin; Lipoxygenase; Prostaglandin-Endoperoxide Synthases; Salicylates; Salicylic Acid

1983
Correlations between changes in indicators of gastric mucosal barrier integrity at time of exposure to "barrier breakers" and extent of hemorrhagic erosions one hour later.
    Digestive diseases and sciences, 1984, Volume: 29, Issue:1

    Topics: Animals; Aspirin; Ethanol; Female; Gastric Mucosa; Gastrointestinal Hemorrhage; Mannitol; Prognosis; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Stomach Ulcer; Taurocholic Acid

1984
The effect of acetylsalicylic acid on renal function in the Pekin duck.
    British journal of pharmacology, 1984, Volume: 82, Issue:2

    Topics: Animals; Arginine Vasopressin; Aspirin; Cyclooxygenase Inhibitors; Diuresis; Ducks; Exocrine Glands; Female; Glomerular Filtration Rate; Kidney; Male; Osmolar Concentration; Renal Circulation; Salicylates; Salicylic Acid

1984
Salicylate:aspirin ratios: relevance to aspirin's antithrombotic action.
    Prostaglandins, leukotrienes, and medicine, 1984, Volume: 14, Issue:2

    Topics: Animals; Aspirin; Binding, Competitive; Cyclooxygenase Inhibitors; Fibrinolytic Agents; Kinetics; Rats; Salicylates; Salicylic Acid

1984
[Divergence between the pharmacologic and clinical effects of inhibitors of prostaglandin synthesis].
    Deutsche medizinische Wochenschrift (1946), 1984, Aug-03, Volume: 109, Issue:31-32

    Topics: Aspirin; Blood Platelets; Dipyridamole; Drug Interactions; Epoprostenol; Humans; Platelet Aggregation; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Salicylates; Salicylic Acid; Sulfinpyrazone; Thrombosis; Thromboxanes

1984
[Comparison of the pharmacokinetic behavior of Turivital, Acesal and Micristin].
    Die Pharmazie, 1984, Volume: 39, Issue:6

    Topics: Adult; Ascorbic Acid; Aspirin; Biological Availability; Caffeine; Carbon Dioxide; Drug Combinations; Drug Interactions; Female; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Kinetics; Male; Salicylates; Salicylic Acid

1984
Inhibition of platelet function by a controlled release acetylsalicylic acid formulation--single and chronic dosing studies.
    European journal of clinical pharmacology, 1984, Volume: 27, Issue:1

    Topics: Adult; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Delayed-Action Preparations; Female; Humans; Male; Malondialdehyde; Platelet Aggregation; Platelet Function Tests; Salicylates; Salicylic Acid; Time Factors

1984
A simple fluorometric method for the determination of salicylic acid in aluminium acetylsalicylate.
    Pharmaceutisch weekblad. Scientific edition, 1984, Jun-22, Volume: 6, Issue:3

    Topics: Aspirin; Hydrogen-Ion Concentration; Salicylates; Salicylic Acid; Spectrometry, Fluorescence; Tablets

1984
Determination of aspirin and salicylic acid in aspirin tablets by second derivative ultraviolet spectrometry.
    Chemical & pharmaceutical bulletin, 1984, Volume: 32, Issue:4

    Topics: Aspirin; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet; Tablets

1984
Comparative aspirin absorption kinetics after administration of sodium- and potassium-containing buffered solutions.
    Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:7

    Topics: Adult; Aspirin; Buffers; Female; Hippurates; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Kinetics; Male; Potassium; Salicylates; Salicylic Acid; Sodium; Solutions

1984
Reye's syndrome: salicylates and mitochondrial functions.
    Biochemical pharmacology, 1984, Sep-15, Volume: 33, Issue:18

    Topics: Animals; Aspirin; Calcium; Humans; Hydroxybutyrates; Mitochondria; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxygen Consumption; Phosphates; Rats; Reye Syndrome; Salicylates; Salicylic Acid; Structure-Activity Relationship; Succinates; Succinic Acid

1984
Actions and interactions of acetylsalicylic acid, salicylic acid and diflunisal on platelet aggregation.
    European journal of clinical pharmacology, 1984, Volume: 27, Issue:2

    Topics: Adult; Aspirin; Diflunisal; Drug Interactions; Female; Humans; Male; Middle Aged; Platelet Aggregation; Salicylates; Salicylic Acid

1984
Difficulty in achieving therapeutic serum concentrations of salicylate in Kawasaki disease.
    The Journal of pediatrics, 1984, Volume: 105, Issue:6

    Topics: Aspirin; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infant; Male; Mucocutaneous Lymph Node Syndrome; Prospective Studies; Retrospective Studies; Salicylates; Salicylic Acid

1984
Rapid and sensitive determination of acetylsalicylic acid and its metabolites using reversed-phase high-performance liquid chromatography.
    Journal of chromatography, 1984, Oct-12, Volume: 310, Issue:2

    Topics: Animals; Aspirin; Biotransformation; Chromatography, High Pressure Liquid; Gentisates; Hippurates; Humans; Hydrogen-Ion Concentration; Rats; Salicylates; Salicylic Acid; Species Specificity

1984
Aspirin metabolites causing misinterpretation of paracetamol results.
    Annals of clinical biochemistry, 1984, Volume: 21 ( Pt 6)

    Topics: Acetaminophen; Aspirin; Biotransformation; Chromatography, High Pressure Liquid; Gentisates; Humans; Hydroxybenzoates; Infant; Male; Salicylates; Salicylic Acid

1984
Improved method for the determination of aspirin and its metabolites in biological fluids by high-performance liquid chromatography: applications to human and animal studies.
    Journal of chromatography, 1984, Nov-28, Volume: 311, Issue:2

    Topics: Animals; Aspirin; Biological Availability; Chromatography, High Pressure Liquid; Gentisates; Hippurates; Humans; Hydroxybenzoates; Kinetics; Rabbits; Rats; Salicylates; Salicylic Acid; Species Specificity

1984
Salicylate prophylaxis in migraine.
    Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie, 1984, Volume: 135, Issue:2

    Topics: Adolescent; Adult; Aged; Aspirin; Female; Humans; Male; Middle Aged; Migraine Disorders; Platelet Aggregation; Salicylates; Salicylic Acid; Vascular Headaches

1984
Minimization of salicylic acid formation during preparation of aspirin products for analysis by high-performance liquid chromatography.
    The Analyst, 1984, Volume: 109, Issue:10

    Topics: Aspirin; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Salicylates; Salicylic Acid

1984
Analysis of tablets containing aspirin, acetaminophen, and ascorbic acid by high-performance liquid chromatography.
    Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:12

    Topics: Acetaminophen; Ascorbic Acid; Aspirin; Chromatography, High Pressure Liquid; Drug Stability; Humidity; Hydrogen-Ion Concentration; Salicylates; Salicylic Acid; Tablets; Temperature; Time Factors

1984
Simultaneous high-performance liquid chromatography assay of acetylsalicylic acid and salicylic acid in film-coated aspirin tablets.
    Journal of chromatography, 1984, Dec-28, Volume: 317

    Topics: Aspirin; Chromatography, High Pressure Liquid; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet; Tablets, Enteric-Coated

1984
Effects of indomethacin, aspirin and related compounds on the transgastric potential difference in cats.
    Archives internationales de pharmacodynamie et de therapie, 1983, Volume: 263, Issue:1

    Topics: Animals; Aspirin; Cats; Dinoprostone; Female; Gastric Mucosa; Indomethacin; Infusions, Parenteral; Intubation, Gastrointestinal; Male; Membrane Potentials; Prostaglandins E; Salicylates; Salicylic Acid; Time Factors

1983
Relevance to redesigning aspirin therapeutic regimens.
    Thrombosis research. Supplement, 1983, Volume: 4

    Topics: Aspirin; Drug Administration Schedule; Humans; Kinetics; Models, Biological; Salicylates; Salicylic Acid

1983
Salicylate does not interfere with aspirin in human blood in vivo.
    Prostaglandins, leukotrienes, and medicine, 1984, Volume: 13, Issue:2

    Topics: Adult; Aspirin; Blood Coagulation; Blood Platelets; Humans; Male; Salicylates; Salicylic Acid; Thromboxane B2; Thromboxanes

1984
Rapidly-adapting receptor activity and intratracheal pressure in guinea pigs. II. Action of aspirin and salicylic acid in antagonizing mediators of allergic asthma.
    Prostaglandins, leukotrienes, and medicine, 1984, Volume: 16, Issue:2

    Topics: Animals; Aspirin; Asthma; Bradykinin; Dinoprost; Guinea Pigs; Histamine; Mechanoreceptors; Muscle, Smooth; Pressure; Prostaglandins F; Pulmonary Stretch Receptors; Salicylates; Salicylic Acid; SRS-A; Trachea

1984
Availability of salicylate from salsalate and aspirin.
    Clinical pharmacology and therapeutics, 1983, Volume: 34, Issue:4

    Topics: Arthritis, Rheumatoid; Aspirin; Biological Availability; Chromatography, High Pressure Liquid; Double-Blind Method; Drug Evaluation; Female; Gentisates; Humans; Hydroxybenzoates; Male; Salicylates; Salicylic Acid

1983
Pharmacokinetics of aspirin and salicylate in elderly subjects and in patients with alcoholic liver disease.
    European journal of clinical pharmacology, 1983, Volume: 25, Issue:2

    Topics: Adult; Aged; Aging; Aspirin; Blood Proteins; Humans; Kinetics; Liver Diseases, Alcoholic; Male; Middle Aged; Models, Biological; Protein Binding; Salicylates; Salicylic Acid

1983
High-performance liquid chromatographic determination of aspirin and its metabolites in plasma and urine.
    Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:9

    Topics: Animals; Aspirin; Biotransformation; Chromatography, High Pressure Liquid; Gentisates; Hippurates; Humans; Rats; Salicylates; Salicylic Acid

1983
Effect of water deprivation on aspirin disposition kinetics.
    Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:9

    Topics: Animals; Aspirin; Biotransformation; Heparin; Injections, Intravenous; Kinetics; Male; Rats; Salicylates; Salicylic Acid; Water Deprivation

1983
[Distribution of salicylic acid and hydrolysis of acetylsalicylic acid in the human fetus in early pregnancy].
    Biomedica biochimica acta, 1983, Volume: 42, Issue:7-8

    Topics: Aspirin; Female; Fetus; Humans; Hydrolysis; Maternal-Fetal Exchange; Pregnancy; Pregnancy Trimester, First; Salicylates; Salicylic Acid; Tissue Distribution

1983
Placental transfer of acetylsalicylic acid (ASA) and salicylic acid (SA) in near-term ewes.
    Progress in clinical and biological research, 1983, Volume: 135

    Topics: Animals; Aspirin; Female; Fetus; Gestational Age; Kinetics; Maternal-Fetal Exchange; Models, Biological; Pregnancy; Salicylates; Salicylic Acid; Sheep

1983
Salicylic acid plasma levels following multiple doses of Norgesic Forte and aspirin.
    Therapeutic drug monitoring, 1983, Volume: 5, Issue:4

    Topics: Adult; Aspirin; Caffeine; Double-Blind Method; Drug Combinations; Female; Humans; Kinetics; Male; Orphenadrine; Salicylates; Salicylic Acid

1983
The effect of the non-steroidal anti-inflammatory drug choline magnesium trisalicylate on gastric mucosal cell exfoliation.
    British journal of clinical pharmacology, 1984, Volume: 17, Issue:1

    Topics: Adult; Aspirin; Choline; Female; Gastric Mucosa; Humans; Male; Random Allocation; Salicylates; Salicylic Acid

1984
Stabilized normal-phase high-performance liquid chromatographic analysis of aspirin and salicylic acid in solid pharmaceutical dosage forms.
    Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:2

    Topics: Antacids; Aspirin; Buffers; Chromatography, High Pressure Liquid; Drug Stability; Salicylates; Salicylic Acid; Tablets

1984
Interaction between frusemide and aspirin.
    General pharmacology, 1984, Volume: 15, Issue:2

    Topics: Adult; Aspirin; Diuresis; Female; Furosemide; Humans; Male; Natriuresis; Potassium; Salicylates; Salicylic Acid

1984
Effect of oral 16,16-dimethyl prostaglandin E2 on gastric mucosal salicylate concentration in the rat.
    Pharmacology, 1984, Volume: 28, Issue:5

    Topics: Administration, Oral; Animals; Aspirin; Chromatography, High Pressure Liquid; Female; Gastric Mucosa; Injections, Intravenous; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid; Stomach Ulcer

1984
Placental drug transfer in near-term ewes: acetylsalicylic and salicylic acid.
    Canadian journal of physiology and pharmacology, 1984, Volume: 62, Issue:4

    Topics: Animals; Aspirin; Computers; Female; Isotope Labeling; Kinetics; Maternal-Fetal Exchange; Models, Biological; Pregnancy; Salicylates; Salicylic Acid; Sheep

1984
Effects of acetylsalicylic acid on human platelet function in vivo at salicylate steady state.
    Thrombosis and haemostasis, 1984, Apr-30, Volume: 51, Issue:2

    Topics: Adult; Aspirin; Collagen; Humans; Male; Platelet Aggregation; Platelet Function Tests; Salicylates; Salicylic Acid

1984
Salicylate-aspirin interaction in the rat. Evidence that salicylate accumulating during aspirin administration may protect vascular prostacyclin from aspirin-induced inhibition.
    The Journal of clinical investigation, 1981, Volume: 68, Issue:4

    Topics: Animals; Aspirin; Biotransformation; Blood Platelets; Cyclooxygenase Inhibitors; Epoprostenol; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Salicylates; Salicylic Acid

1981
Salicylic acid blocks indomethacin- and aspirin-induced cyclo-oxygenase inhibition in rat gastric mucosa.
    Gastroenterology, 1982, Volume: 83, Issue:5

    Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Dinoprost; Drug Interactions; Gastric Mucosa; Indomethacin; Male; Prostaglandin Antagonists; Prostaglandins F; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid

1982
Determination of salicylic acid in aspirin powder by second derivative ultraviolet spectrometry.
    Analytical chemistry, 1983, Volume: 55, Issue:1

    Topics: Aspirin; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet

1983
Determination of acetylsalicylic acid and metabolites in biological fluids by high-performance liquid chromatography.
    Journal of chromatography, 1983, Feb-11, Volume: 272, Issue:2

    Topics: Animals; Aspirin; Chromatography, High Pressure Liquid; Gentisates; Hippurates; Humans; Kinetics; Male; Rabbits; Salicylates; Salicylic Acid; Specimen Handling

1983
Plasma levels of acetylsalicylic acid and salicylic acid after oral ingestion of plain and buffered acetylsalicylic acid in relation to bleeding time and thrombocyte function.
    Pharmaceutisch weekblad. Scientific edition, 1983, Feb-25, Volume: 5, Issue:1

    Topics: Adult; Aspirin; Bleeding Time; Blood Coagulation; Blood Platelets; Buffers; Humans; Kinetics; Male; Platelet Aggregation; Platelet Function Tests; Salicylates; Salicylic Acid

1983
Protection from arrhythmias of cultured heart cells by nonsteroidal antiinflammatory drugs.
    Pharmacological research communications, 1983, Volume: 15, Issue:2

    Topics: Animals; Animals, Newborn; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Aspirin; Cells, Cultured; Indomethacin; Rats; Salicylates; Salicylic Acid; Sulfinpyrazone; Time Factors

1983
In vitro and in vivo evaluation of two preparations of activated charcoal as adsorbents of aspirin.
    Human toxicology, 1983, Volume: 2, Issue:2

    Topics: Adsorption; Adult; Aspirin; Biological Availability; Charcoal; Female; Humans; Male; Salicylates; Salicylic Acid; Time Factors

1983
Combined embryotoxic action of toluene, a widely used industrial chemical, and acetylsalicylic acid (aspirin).
    Teratology, 1983, Volume: 27, Issue:2

    Topics: Abnormalities, Drug-Induced; Amniotic Fluid; Animals; Aspirin; Drug Interactions; Embryo, Mammalian; Female; Gestational Age; Glycine; Pregnancy; Rats; Salicylates; Salicylic Acid; Teratogens; Toluene

1983
Sensitive salicylate assay in plasma with a 'reversed' Berthelot's reaction.
    Clinica chimica acta; international journal of clinical chemistry, 1983, Jul-15, Volume: 131, Issue:3

    Topics: Aspirin; Chemical Phenomena; Chemistry; Chloramines; Colorimetry; Humans; Pyruvates; Pyruvic Acid; Salicylates; Salicylic Acid; Time Factors

1983
Influence of food on aspirin absorption from tablets and buffered solutions.
    Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:7

    Topics: Adult; Aspirin; Buffers; Food; Humans; Intestinal Absorption; Male; Salicylates; Salicylic Acid; Solutions; Tablets

1983
In vivo and in vitro studies on the binding of salicylate to human plasma proteins: evidence for one type of binding site.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 220, Issue:3

    Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Binding Sites; Blood Proteins; Female; Humans; In Vitro Techniques; Kinetics; Male; Middle Aged; Protein Binding; Salicylates; Salicylic Acid

1982
Endogenous gastric mucosal prostaglandins: their role in mucosal integrity.
    The American journal of physiology, 1982, Volume: 242, Issue:4

    Topics: Animals; Aspirin; Biological Transport, Active; Dogs; Gastric Mucosa; Prostaglandins; Salicylates; Salicylic Acid; Sodium

1982
Gastric emptying and absorption of acetylsalicylic acid administered as enteric-coated micro-granules.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:1

    Topics: Adult; Aspirin; Capsules; Delayed-Action Preparations; Gastric Emptying; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Male; Salicylates; Salicylic Acid

1982
Determination of related compounds in aspirin by liquid chromatography.
    Journal of pharmaceutical sciences, 1982, Volume: 71, Issue:5

    Topics: Aspirin; Chromatography, Liquid; Salicylates; Salicylic Acid; Tablets

1982
Bioavailability of acetylsalicylic acid and salicylic acid from rapid-and slow-release formulations, and in combination with dipyridamol.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:4

    Topics: Adult; Aspirin; Biological Availability; Delayed-Action Preparations; Dipyridamole; Female; Humans; Kinetics; Male; Salicylates; Salicylic Acid

1982
Inhibition of anaerobic glycolysis in bovine retina extracts by salicylate and acetylsalicylate.
    The International journal of biochemistry, 1982, Volume: 14, Issue:9

    Topics: Animals; Aspirin; Cattle; Glucose; Glycolysis; In Vitro Techniques; Lactates; Lactic Acid; Oxygen; Retina; Salicylates; Salicylic Acid

1982
[Studies on the pharmacological bases of fetal toxicity of drugs. (I). Relation of fetal toxicity and tissue concentration of acetylsalicylic acid with pyrogen in pregnant rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 79, Issue:5

    Topics: Abnormalities, Drug-Induced; Adenosine Triphosphate; Animals; Aspirin; Body Weight; Drug Synergism; Female; Fetus; Humans; Infant, Newborn; Lipopolysaccharides; Male; Maternal-Fetal Exchange; Pregnancy; Pyrogens; Rats; Salicylates; Salicylic Acid; Tissue Distribution

1982
Aspirin--a national survey V: Determination of aspirin and impurities in enteric coated tablets and suppository formulations and in vitro dissolution of enteric coated tablets.
    Journal of pharmaceutical sciences, 1982, Volume: 71, Issue:9

    Topics: Aspirin; Chromatography, Thin Layer; Drug Contamination; Salicylates; Salicylic Acid; Solubility; Suppositories; Tablets, Enteric-Coated; United States

1982
The transmural gastric potential difference in combination with pharmacokinetic profiles. A new approach to combine kinetic and dynamic properties of compounds.
    Methods and findings in experimental and clinical pharmacology, 1982, Volume: 4, Issue:7

    Topics: Adolescent; Adult; Aspirin; Buffers; Double-Blind Method; Drug Combinations; Female; Gastric Mucosa; Humans; Kinetics; Male; Membrane Potentials; Models, Biological; Salicylates; Salicylic Acid

1982
Systemic availability of acetylsalicylic acid in human subjects after oral ingestion of three different formulations.
    Acta pharmacologica et toxicologica, 1982, Volume: 51, Issue:4

    Topics: Administration, Oral; Aspirin; Biological Availability; Biotransformation; Delayed-Action Preparations; Humans; Kinetics; Salicylates; Salicylic Acid

1982
Spectrofluorometric determination of acetylsalicylic acid, salicylamide, and salicyclic acid as an impurity in pharmaceutical preparations.
    Journal of pharmaceutical sciences, 1981, Volume: 70, Issue:6

    Topics: Acetaminophen; Aspirin; Buffers; Caffeine; Drug Combinations; Drug Contamination; Salicylamides; Salicylates; Salicylic Acid; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet

1981
Gastric cytoprotection by sodium salicylate.
    Prostaglandins, 1981, Volume: 21 Suppl

    Topics: Animals; Aspirin; Ethanol; Gastric Mucosa; Indomethacin; Male; Rats; Salicylates; Salicylic Acid; Stomach Ulcer; Structure-Activity Relationship

1981
General model for dissolution rates of n-component, nondisintegrating spheres.
    Journal of pharmaceutical sciences, 1981, Volume: 70, Issue:12

    Topics: Aspirin; Caffeine; Chemical Phenomena; Chemistry, Physical; Drug Combinations; Kinetics; Models, Chemical; Phenacetin; Salicylates; Salicylic Acid; Solubility

1981
Effect of multiple-dose activated charcoal on the clearance of high-dose intravenous aspirin in a porcine model.
    Annals of emergency medicine, 1995, Volume: 26, Issue:5

    Topics: Animals; Antidotes; Aspirin; Charcoal; Cross-Over Studies; Disease Models, Animal; Drug Evaluation, Preclinical; Metabolic Clearance Rate; Poisoning; Salicylates; Salicylic Acid; Swine; Time Factors

1995
Pharmacokinetics and pharmacodynamics in copper deficiency. I. Antiinflammatory activity of aspirin.
    Biological trace element research, 1994, Volume: 40, Issue:2

    Topics: Analysis of Variance; Animals; Aspirin; Carboxylic Ester Hydrolases; Chromatography, High Pressure Liquid; Copper; Diet; Edema; Male; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid

1994
Salicylate poisoning: two-dimensional J-resolved NMR urinalysis.
    NMR in biomedicine, 1995, Volume: 8, Issue:1

    Topics: Adolescent; Aspirin; Female; Gentisates; Hippurates; Humans; Hydroxybenzoates; Magnetic Resonance Spectroscopy; Poisoning; Salicylates; Salicylic Acid

1995
Aspirin, salicylate, sulfite and tartrazine induced bronchoconstriction. Safe doses and case definition in epidemiological studies.
    Journal of clinical epidemiology, 1995, Volume: 48, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Bronchoconstriction; Drug Hypersensitivity; Environmental Exposure; Epidemiologic Methods; False Positive Reactions; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Salicylates; Salicylic Acid; Sulfites; Tartrazine

1995
Aspirin as a free radical scavenger: consequences for therapy of cerebrovascular ischemia.
    Stroke, 1995, Volume: 26, Issue:10

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Cerebrovascular Disorders; Cyclooxygenase Inhibitors; Female; Free Radical Scavengers; Gentisates; Humans; Hydroxybenzoates; Male; Neuroprotective Agents; Platelet Aggregation Inhibitors; Salicylates; Salicylic Acid

1995
Protein binding of acetylsalicylic acid and salicylic acid in porcine and human serum.
    Veterinary and human toxicology, 1995, Volume: 37, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Proteins; Drug Overdose; Esterases; Humans; In Vitro Techniques; Isotope Labeling; Pilot Projects; Protein Binding; Salicylates; Salicylic Acid; Serum Albumin; Swine; Ultrafiltration

1995
Chronopharmacological study of acetylsalicylic acid in mice.
    European journal of pharmacology, 1995, Jul-01, Volume: 293, Issue:2

    Topics: Analgesics; Animals; Aspirin; Body Temperature; Circadian Rhythm; Male; Mice; Mice, Inbred ICR; Pain Measurement; Salicylates; Salicylic Acid

1995
High-performance liquid chromatography-electrochemical determination of salicylate hydroxylation products as an in vivo marker of oxidative stress.
    Analytical biochemistry, 1995, May-01, Volume: 227, Issue:1

    Topics: Adult; Aspirin; Calibration; Chromatography, High Pressure Liquid; Female; Free Radical Scavengers; Gentisates; Humans; Hydroxybenzoates; Hydroxyl Radical; Male; Oxidative Stress; Reproducibility of Results; Salicylates; Salicylic Acid; Thiobarbituric Acid Reactive Substances

1995
Disposition kinetics of aspirin in female New Zealand white rabbits.
    Laboratory animal science, 1995, Volume: 45, Issue:1

    Topics: Animals; Aspirin; Body Weight; Chromatography, High Pressure Liquid; Female; Kinetics; Rabbits; Salicylates; Salicylic Acid

1995
The quantitative determination of aspirin and its degradation products in a model solution aerosol.
    Journal of pharmaceutical and biomedical analysis, 1995, Volume: 13, Issue:2

    Topics: Administration, Inhalation; Aerosols; Aspirin; Chemistry, Pharmaceutical; Chromatography; Reference Standards; Salicylates; Salicylic Acid; Solutions

1995
Zero-crossing first and second derivative synchronous fluorescence spectroscopic determination of aspirin metabolites in urine.
    Journal of pharmaceutical and biomedical analysis, 1994, Volume: 12, Issue:10

    Topics: Aspirin; Hippurates; Humans; Indicators and Reagents; Salicylates; Salicylic Acid; Spectrometry, Fluorescence

1994
Salicylamide reverses the aspirin-antagonistic effect of salicylic acid on rat platelet cyclooxygenase.
    Prostaglandins, leukotrienes, and essential fatty acids, 1994, Volume: 51, Issue:5

    Topics: Animals; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Male; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Salicylamides; Salicylates; Salicylic Acid; Thromboxane B2

1994
Copper(II) interactions with nonsteroidal antiinflammatory agents. I. Salicylic acid and acetylsalicylic acid.
    Journal of inorganic biochemistry, 1995, Feb-15, Volume: 57, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cations, Divalent; Copper; Gastric Juice; Hydrogen-Ion Concentration; In Vitro Techniques; Models, Biological; Salicylates; Salicylic Acid

1995
Potentiation by caffeine of the analgesic effect of aspirin in the pain-induced functional impairment model in the rat.
    Canadian journal of physiology and pharmacology, 1994, Volume: 72, Issue:10

    Topics: Animals; Aspirin; Caffeine; Drug Synergism; Female; Gentisates; Hindlimb; Hydroxybenzoates; Pain; Rats; Rats, Wistar; Salicylates; Salicylic Acid

1994
Aspirin inhibits secretagogue-stimulated and postprandial pancreatic exocrine secretion in conscious rats.
    Pancreas, 1995, Volume: 10, Issue:1

    Topics: Animals; Aspirin; Cholecystokinin; Dinoprostone; Food; Indomethacin; Male; Pancreas; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Secretin; Stimulation, Chemical

1995
No aspirin in red wine.
    Lancet (London, England), 1994, Sep-10, Volume: 344, Issue:8924

    Topics: Aspirin; Cardiovascular Diseases; Free Radical Scavengers; Humans; Salicylates; Salicylic Acid; Wine

1994
Spectrofluorimetry at zero angle: determination of salicylic acid in an acetylsalicylic acid pharmaceutical formulation.
    The Analyst, 1994, Volume: 119, Issue:7

    Topics: Aspirin; Chromatography, High Pressure Liquid; Drug Storage; Salicylates; Salicylic Acid; Spectrometry, Fluorescence

1994
Use of isosbestic points of derivative absorption curves: the dissolution rate determination of aspirin.
    Journal of pharmaceutical and biomedical analysis, 1994, Volume: 12, Issue:7

    Topics: Adsorption; Aspirin; Hydrolysis; Kinetics; Salicylates; Salicylic Acid; Solubility; Spectrophotometry, Ultraviolet

1994
[Determination of trace amounts of salicylic acid and acetylsalicylic acid in polopirin and other drugs containing acetylsalicylic acid].
    Acta poloniae pharmaceutica, 1993, Volume: 50, Issue:2-3

    Topics: Aspirin; Chromatography, Liquid; Salicylates; Salicylic Acid

1993
Comparison of assay methods by second-derivative spectroscopy, colorimetry and fluorescence spectroscopy of salicylic acid in aspirin preparations with a high-performance liquid chromatographic method.
    Journal of pharmaceutical and biomedical analysis, 1994, Volume: 12, Issue:3

    Topics: Aspirin; Chromatography, High Pressure Liquid; Colorimetry; Reproducibility of Results; Salicylates; Salicylic Acid; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tablets

1994
Acetylsalicylic acid--inducer of cytochrome P-450 2E1?
    Archives of toxicology, 1994, Volume: 68, Issue:4

    Topics: Animals; Aspirin; Carboxyhemoglobin; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Methylene Chloride; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Rats; Rats, Wistar; Salicylates; Salicylic Acid

1994
N-acetyl-beta-D-glucosaminidase (NAG) and alanine aminopeptidase (AAP) excretion after acute administration of acetaminophen, salsalate and aspirin in rats.
    Research communications in chemical pathology and pharmacology, 1993, Volume: 81, Issue:1

    Topics: Acetaminophen; Acetylglucosaminidase; Administration, Oral; Aminopeptidases; Animals; Aspirin; CD13 Antigens; Diuresis; Female; Kidney; Potassium; Rats; Rats, Wistar; Salicylates; Salicylic Acid; Sodium; Spectrophotometry, Atomic

1993
Studies on the reactivity of acyl glucuronides--VII. Salicyl acyl glucuronide reactivity in vitro and covalent binding of salicylic acid to plasma protein of humans taking aspirin.
    Biochemical pharmacology, 1994, Feb-09, Volume: 47, Issue:3

    Topics: Animals; Aspirin; Buffers; Glucuronates; Half-Life; Humans; Hydrogen-Ion Concentration; Rats; Salicylates; Salicylic Acid; Serum Albumin

1994
Effects of acetylsalicylic acid on pulmonary vascular tone and membrane permeability in blood-perfused dog lung.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 75, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Airway Resistance; Animals; Aspirin; Blood Pressure; Capillary Permeability; Dogs; Extravascular Lung Water; Female; Leukotrienes; Male; Muscle, Smooth, Vascular; Organ Size; Perfusion; Pulmonary Circulation; Salicylates; Salicylic Acid; Thromboxane B2; Vascular Resistance

1993
Aspirin-like drugs inhibit neuronally evoked responses in isolated guinea-pig ileum.
    Annali dell'Istituto superiore di sanita, 1993, Volume: 29, Issue:3

    Topics: Acetylcholine; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzydamine; Cyclooxygenase Inhibitors; Guinea Pigs; Ileum; Indomethacin; Isotonic Contraction; Male; Muscle, Smooth; Naloxone; Parasympathetic Nervous System; Receptors, Opioid; Salicylates; Salicylic Acid; Sincalide

1993
Slow release aspirin in the elderly.
    Journal of the Royal Society of Medicine, 1994, Volume: 87, Issue:3

    Topics: Aged; Aged, 80 and over; Aspirin; Delayed-Action Preparations; Female; Humans; Male; Salicylates; Salicylic Acid; Vascular Diseases

1994
Gallbladder contractility in aspirin- and cholesterol-fed prairie dogs.
    Gastroenterology, 1994, Volume: 106, Issue:6

    Topics: Animals; Aspirin; Cholesterol; Crystallization; Diet; Dose-Response Relationship, Drug; Gallbladder; Male; Muscle Contraction; Muscle, Smooth; Prostaglandins; Salicylates; Salicylic Acid; Sciuridae; Sincalide

1994
Plasma acetylsalicylic acid and salicylic acid levels during aspirin provocation in aspirin-sensitive subjects.
    Allergy, 1994, Volume: 49, Issue:1

    Topics: Administration, Oral; Adult; Airway Obstruction; Aspirin; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; Free Radical Scavengers; Humans; Male; Middle Aged; Salicylates; Salicylic Acid; Sodium Salicylate

1994
Plasma salicylate concentrations in immature dogs following aspirin administration: comparison with adult dogs.
    Journal of veterinary pharmacology and therapeutics, 1993, Volume: 16, Issue:3

    Topics: Administration, Oral; Aging; Animals; Aspirin; Dogs; Female; Fluorescence Polarization Immunoassay; Half-Life; Injections, Intravenous; Male; Salicylates; Salicylic Acid

1993
A clinical trial of a slow-release formulation of acetylsalicylic acid in patients at risk for preeclampsia.
    British journal of clinical pharmacology, 1993, Volume: 35, Issue:6

    Topics: Adult; Aspirin; Delayed-Action Preparations; Female; Fetal Blood; Humans; Indicators and Reagents; Infant, Newborn; Maternal-Fetal Exchange; Pre-Eclampsia; Pregnancy; Risk; Salicylates; Salicylic Acid; Thromboxane A2

1993
Transdermal modification of platelet function. A dermal aspirin preparation selectively inhibits platelet cyclooxygenase and preserves prostacyclin biosynthesis.
    Circulation, 1993, Volume: 88, Issue:2

    Topics: Administration, Cutaneous; Adult; Aspirin; Blood Platelets; Bradykinin; Cyclooxygenase Inhibitors; Epoprostenol; Female; Humans; Male; Middle Aged; Salicylates; Salicylic Acid; Thromboxane B2

1993
Transport of aspirin and its metabolites through human erythrocyte membrane.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:2

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Aspirin; Chemical Phenomena; Chemistry, Physical; Culture Media; Cytosol; Erythrocyte Membrane; Gentisates; Hippurates; Humans; Hydrolysis; Hydroxybenzoates; In Vitro Techniques; Salicylates; Salicylic Acid

1993
Effect of aspirin on conformation and dynamics of membrane proteins in platelets and erythrocytes.
    Biochemical pharmacology, 1993, Mar-24, Volume: 45, Issue:6

    Topics: Anilino Naphthalenesulfonates; Aspirin; Blood Platelets; Cell Membrane; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Humans; Membrane Proteins; Protein Conformation; Salicylates; Salicylic Acid; Spin Labels; Tryptophan

1993
Platelet adhesivity to subendothelium is influenced by polymorphonuclear leukocytes: studies with aspirin and salicylate.
    Haemostasis, 1993, Volume: 23, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Alprostadil; Animals; Aspirin; Blood Platelets; Cell Communication; Cyclooxygenase Inhibitors; Endothelium, Vascular; Humans; Lipoxygenase Inhibitors; Neutrophils; Platelet Adhesiveness; Rabbits; Salicylates; Salicylic Acid; Thromboxane B2

1993
Griseofulvin significantly decreases serum salicylate concentrations.
    The Pediatric infectious disease journal, 1993, Volume: 12, Issue:4

    Topics: Aspirin; Child; Griseofulvin; Humans; Male; Rheumatic Heart Disease; Salicylates; Salicylic Acid; Tinea Capitis

1993
Reinduction of the hypnotic effects of thiopental with NSAIDs by decreasing thiopental plasma protein binding in humans.
    Acta anaesthesiologica Scandinavica, 1993, Volume: 37, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Proteins; Female; Humans; Hypnotics and Sedatives; Ibuprofen; In Vitro Techniques; Longitudinal Studies; Middle Aged; Naproxen; Protein Binding; Salicylates; Salicylic Acid; Sleep; Temperature; Thiopental

1993
Liposome capillary electrophoresis for analysis of interactions between lipid bilayers and solutes.
    Electrophoresis, 1995, Volume: 16, Issue:8

    Topics: Amino Acid Sequence; Aspirin; Electrophoresis, Capillary; Lipid Bilayers; Liposomes; Molecular Sequence Data; Molecular Structure; Peptides; Pharmaceutical Preparations; Salicylates; Salicylic Acid; Sulfasalazine; Thermodynamics; Warfarin

1995
[The effect of salicylates on the toxicity of GABAlytics for mice].
    Biulleten' eksperimental'noi biologii i meditsiny, 1995, Volume: 119, Issue:6

    Topics: Animals; Aspirin; Bicuculline; Drug Interactions; GABA Antagonists; Male; Mice; Picrotoxin; Protein Synthesis Inhibitors; Receptors, GABA-A; Salicylates; Salicylic Acid; Serum Albumin

1995
Modification by analgesics of the susceptibility to antibiotics in Serratia marcescens.
    The new microbiologica, 1995, Volume: 18, Issue:4

    Topics: Acetaminophen; Analgesics; Anti-Bacterial Agents; Aspirin; Bacterial Outer Membrane Proteins; beta-Lactamases; Cell Membrane Permeability; Drug Interactions; Drug Resistance, Microbial; Humans; In Vitro Techniques; Salicylates; Salicylic Acid; Serratia marcescens

1995
Maternal reproductive effects of oral salicylic acid in Sprague-Dawley rats.
    Toxicology letters, 1996, Volume: 84, Issue:3

    Topics: Administration, Oral; Animals; Aspirin; Dose-Response Relationship, Drug; Embryonic and Fetal Development; Female; Fetus; Labor, Obstetric; Male; No-Observed-Adverse-Effect Level; Pregnancy; Pregnancy, Animal; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Structure-Activity Relationship

1996
Salicylate or aspirin inhibits the induction of the inducible nitric oxide synthase in rat cardiac fibroblasts.
    Circulation research, 1996, Volume: 78, Issue:5

    Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Enzyme Induction; Fibroblasts; Interleukin-1; Myocardium; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; RNA, Messenger; Salicylates; Salicylic Acid; Tumor Necrosis Factor-alpha

1996
Systemic inflammatory response syndrome caused by chronic salicylate intoxication.
    Southern medical journal, 1996, Volume: 89, Issue:5

    Topics: Acid-Base Imbalance; Adult; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chronic Disease; Disseminated Intravascular Coagulation; Female; Fever; Humans; Hypotension; Male; Middle Aged; Pulmonary Edema; Salicylates; Salicylic Acid; Systemic Inflammatory Response Syndrome

1996
The pharmacokinetics of salicylate in dairy cattle are not altered by simultaneous intravenous ceftiofur sodium and DL-lysine-acetyl salicylate (aspirin).
    Journal of veterinary pharmacology and therapeutics, 1996, Volume: 19, Issue:2

    Topics: Animals; Aspirin; Cattle; Cephalosporins; Chromatography, High Pressure Liquid; Cross-Over Studies; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Half-Life; Injections, Intravenous; Reference Standards; Salicylates; Salicylic Acid

1996
The disposition of aspirin and salicylic acid in the isolated perfused rat liver: the effect of normal and retrograde flow on availability and mean transit time.
    The Journal of pharmacy and pharmacology, 1996, Volume: 48, Issue:7

    Topics: Animals; Aspirin; Female; In Vitro Techniques; Liver; Perfusion; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Sucrose

1996
Aspirin related gastrointestinal bleeders have an exaggerated bleeding time response due to aspirin use.
    Gut, 1996, Volume: 39, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Blood Coagulation; Factor VIII; Female; Gastrointestinal Hemorrhage; Hematocrit; Humans; Male; Middle Aged; Regression Analysis; Risk Factors; Salicylates; Salicylic Acid; Smoking; von Willebrand Factor

1996
A highly sensitive HPLC method for the simultaneous determination of acetylsalicylic, salicylic and salicyluric acids in biologic fluids: pharmacokinetic, metabolic and monitoring implications.
    Methods and findings in experimental and clinical pharmacology, 1996, Volume: 18, Issue:8

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromatography, High Pressure Liquid; Female; Hippurates; Humans; Male; Salicylates; Salicylic Acid

1996
Fluorimetric determination of tissue distribution and differences between the activity of aspirin esterases I and II in mice and rats.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:3

    Topics: Adrenal Glands; Animals; Aspirin; Brain; Carboxylic Ester Hydrolases; In Vitro Techniques; Isoenzymes; Kidney; Liver; Male; Mice; Organ Specificity; Rats; Rats, Wistar; Salicylates; Salicylic Acid; Species Specificity; Spectrometry, Fluorescence

1997
Comparative cytotoxicity of 5-aminosalicylic acid (mesalazine) and related compounds in different cell lines.
    Cell biology and toxicology, 1997, Volume: 13, Issue:6

    Topics: Aminosalicylic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Dogs; Glutathione; Humans; Kidney Tubules; Mesalamine; Neutral Red; Rats; Salicylates; Salicylic Acid; Structure-Activity Relationship; Swine; Tumor Cells, Cultured

1997
Euglena gracilis as an eukaryotic test organism for detecting mutagens and antimutagens.
    Mutation research, 1997, Sep-18, Volume: 393, Issue:1-2

    Topics: 4-Aminobenzoic Acid; Aminosalicylic Acid; Animals; Antimutagenic Agents; Aspirin; Chloroplasts; Euglena gracilis; Eukaryotic Cells; Methylnitronitrosoguanidine; Methylnitrosourea; Mutagenicity Tests; Mutagens; Mutation; ortho-Aminobenzoates; Pigmentation; Salicylates; Salicylic Acid; Sodium Salicylate

1997
Effect of aspirin and salicylate on LDL oxidation in vitro.
    Biochemical Society transactions, 1997, Volume: 25, Issue:3

    Topics: Aspirin; Humans; Kinetics; Lipoproteins, LDL; Salicylates; Salicylic Acid; Ultraviolet Rays

1997
Direct assay and shelf-life monitoring of aspirin tablets using Raman spectroscopy.
    Journal of pharmaceutical and biomedical analysis, 1997, Volume: 16, Issue:1

    Topics: Anti-Inflammatory Agents; Aspirin; Chromatography, High Pressure Liquid; Drug Storage; Reproducibility of Results; Salicylates; Salicylic Acid; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Tablets

1997
Determination of aspirin and salicylic acid in human plasma by column-switching liquid chromatography using on-line solid-phase extraction.
    Analytical chemistry, 1998, Jan-15, Volume: 70, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Specimen Collection; Chromatography, High Pressure Liquid; Humans; Salicylates; Salicylic Acid

1998
Determination of acetylsalicylic acid and salicylic acid in skin and plasma by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 1998, Feb-13, Volume: 705, Issue:2

    Topics: Administration, Oral; Administration, Topical; Area Under Curve; Aspirin; Chromatography, High Pressure Liquid; Epidermis; Humans; Reference Values; Reproducibility of Results; Salicylates; Salicylic Acid; Sensitivity and Specificity; Skin

1998
Protein binding of aspirin and salicylate measured by in vivo ultrafiltration.
    Clinical pharmacology and therapeutics, 1998, Volume: 63, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Blood Proteins; Female; Half-Life; Humans; Male; Middle Aged; Protein Binding; Reference Values; Salicylates; Salicylic Acid; Ultrafiltration

1998
Continuous release of vasodilator prostanoids contributes to regulation of resting forearm blood flow in humans.
    The American journal of physiology, 1998, Volume: 274, Issue:4

    Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Adult; Aspirin; Dose-Response Relationship, Drug; Female; Forearm; Humans; Male; Nitroprusside; Norepinephrine; Oxygen Consumption; Prostaglandins; Regional Blood Flow; Rest; Salicylates; Salicylic Acid; Time Factors; Vasodilation

1998
Determination of aspirin and salicylic acid in transdermal perfusates.
    Journal of chromatography. B, Biomedical sciences and applications, 1998, Apr-10, Volume: 707, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calibration; Chromatography, High Pressure Liquid; Indicators and Reagents; Mice; Reference Standards; Reproducibility of Results; Salicylates; Salicylic Acid; Skin

1998
Aspirin and salicylate induce apoptosis and activation of caspases in B-cell chronic lymphocytic leukemia cells.
    Blood, 1998, Aug-15, Volume: 92, Issue:4

    Topics: Aged; Amino Acid Chloromethyl Ketones; Annexins; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; B-Lymphocytes; Cell Survival; Cyclooxygenase Inhibitors; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Activation; Female; Humans; Indomethacin; Ketorolac; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Neoplasm Proteins; Nitrobenzenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteins; Salicylates; Salicylic Acid; Sulfonamides; Tolmetin; Tumor Cells, Cultured

1998
A new salicylate ISFET for the determination of salicylic and acetylsalicylic acid in drugs.
    Journal of pharmaceutical and biomedical analysis, 1995, Volume: 13, Issue:4-5

    Topics: Aspirin; Ion-Selective Electrodes; Membranes, Artificial; Ointments; Polyvinyl Chloride; Potentiometry; Salicylates; Salicylic Acid; Tablets; Transistors, Electronic

1995
Aspirin and salicylate protect against MPTP-induced dopamine depletion in mice.
    Journal of neurochemistry, 1998, Volume: 71, Issue:4

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Aspirin; Body Temperature; Corpus Striatum; Cyclooxygenase Inhibitors; Dexamethasone; Dopamine; Hydroxybenzoates; Hydroxyl Radical; Lysine; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; MPTP Poisoning; Salicylates; Salicylic Acid; Serotonin; Synaptosomes

1998
Assay of acetylsalicylic acid and three of its metabolites in human plasma and urine using non-aqueous capillary electrophoresis with reversed electroosmotic flow.
    Journal of pharmaceutical and biomedical analysis, 1998, Sep-01, Volume: 17, Issue:6-7

    Topics: Acetonitriles; Aspirin; Electrophoresis, Capillary; Gentisates; Hexadimethrine Bromide; Hippurates; Humans; Hydrogen-Ion Concentration; Hydroxybenzoates; In Vitro Techniques; Methanol; Osmosis; Reproducibility of Results; Salicylic Acid; Temperature

1998
Simultaneous determination of salicylic acid and acetylsalicylic acid in aspirin delayed-release tablet formulations by second-derivative UV spectrophotometry.
    Journal of pharmaceutical and biomedical analysis, 1998, Volume: 18, Issue:4-5

    Topics: Aspirin; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Salicylic Acid; Spectrophotometry, Ultraviolet; Tablets

1998
Effects of antiaggregant and antiinflammatory doses of aspirin on coronary hemodynamics and myocardial reactive hyperemia in conscious dogs.
    Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Bradykinin; Coronary Disease; Coronary Vessels; Cyclooxygenase Inhibitors; Diclofenac; Dogs; Dose-Response Relationship, Drug; Hyperemia; Male; Myocardium; Nitric Oxide Synthase; Nitroarginine; Salicylic Acid; Thromboxane B2; Time Factors

1999
Salicylate-induced kidney mitochondrial permeability transition is prevented by cyclosporin A.
    Toxicology letters, 1999, Mar-08, Volume: 105, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calcium; Cyclosporine; Immunosuppressive Agents; In Vitro Techniques; Kidney; Male; Mitochondria; Mitochondrial Swelling; Permeability; Rats; Rats, Sprague-Dawley; Salicylic Acid

1999
Prevention of small black spots on sugar-coated tablets containing aluminum acetylsalicylic acid.
    Drug development and industrial pharmacy, 1999, Volume: 25, Issue:4

    Topics: Acetic Acid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carbohydrates; Chelating Agents; Drug Contamination; Drug Interactions; Ferric Compounds; Humidity; Hydrochloric Acid; Magnesium; Salicylic Acid; Tablets, Enteric-Coated; Talc

1999
Synthesis of [11C]salicylic acid and related compounds and their biodistribution in mice.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 1999, Volume: 50, Issue:5

    Topics: Acetylation; Animals; Anti-Infective Agents; Aspirin; Brain; Carbon Radioisotopes; Hydroxybenzoate Ethers; Isotope Labeling; Male; Mice; Radiopharmaceuticals; Salicylates; Salicylic Acid; Tissue Distribution

1999
Salicylate promotes myeloperoxidase-initiated LDL oxidation: antagonization by its metabolite gentisic acid.
    Free radical biology & medicine, 1999, Volume: 26, Issue:9-10

    Topics: Arteriosclerosis; Aspirin; Free Radical Scavengers; Free Radicals; Gentisates; Humans; Hydroxybenzoates; In Vitro Techniques; Lipid Peroxidation; Lipoproteins, LDL; Neutrophils; Oxidants; Oxidation-Reduction; Peroxidase; Phenols; Salicylic Acid; Tyrosine

1999
Ingestion of chilli pepper (Capsicum annuum) reduces salicylate bioavailability after oral asprin administration in the rat.
    Canadian journal of physiology and pharmacology, 1999, Volume: 77, Issue:6

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biological Availability; Capsicum; Male; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Salicylic Acid

1999
Salicylic acid and aspirin inhibit the activity of RSK2 kinase and repress RSK2-dependent transcription of cyclic AMP response element binding protein- and NF-kappa B-responsive genes.
    Journal of immunology (Baltimore, Md. : 1950), 1999, Nov-15, Volume: 163, Issue:10

    Topics: 3T3 Cells; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; Interphase; Lipopolysaccharides; Mice; Mitogens; Monocytes; NF-kappa B; Phosphoproteins; Phosphorylation; Promoter Regions, Genetic; Ribosomal Protein S6 Kinases; Salicylic Acid; Substrate Specificity; Transcription, Genetic

1999
Aspirin and salicylic acid do not inhibit methyl jasmonate-inducible expression of a gene for ornithine decarboxylase in tobacco BY-2 cells.
    Bioscience, biotechnology, and biochemistry, 2000, Volume: 64, Issue:1

    Topics: Acetates; Amino Acids; Aspirin; Bacterial Toxins; Cells, Cultured; Cloning, Molecular; Cyclopentanes; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Indenes; Molecular Sequence Data; Nicotiana; Ornithine Decarboxylase; Oxylipins; Plants, Toxic; Salicylic Acid

2000
The salicylate metabolite gentisic acid, but not the parent drug, inhibits glucose autoxidation-mediated atherogenic modification of low density lipoprotein.
    FEBS letters, 2000, Mar-17, Volume: 470, Issue:1

    Topics: Arteriosclerosis; Aspirin; Cells, Cultured; Diabetic Angiopathies; Endothelium, Vascular; Gentisates; Glucose; Humans; Hydroxybenzoates; Iron Chelating Agents; Lipoproteins, LDL; Male; Oxidation-Reduction; Prodrugs; Reactive Oxygen Species; Salicylic Acid; Thromboplastin

2000
Protection by free oxygen radical scavenging enzymes against salicylate-induced embryonic malformations in vitro.
    Toxicology in vitro : an international journal published in association with BIBRA, 2000, Volume: 14, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Drug Interactions; Embryonic and Fetal Development; Female; Free Radical Scavengers; Glutathione; Male; Organ Culture Techniques; Pregnancy; Rats; Rats, Wistar; Reactive Oxygen Species; Salicylic Acid; Sodium Salicylate; Superoxide Dismutase

2000
Lack of gastric toxicity of nitric oxide-releasing aspirin, NCX-4016, in the stomach of diabetic rats.
    Life sciences, 2000, Aug-18, Volume: 67, Issue:13

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Diabetes Mellitus, Experimental; Gastric Acid; Gastric Mucosa; Gastrointestinal Hemorrhage; Male; Nitric Oxide Donors; Nitro Compounds; Omeprazole; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Salicylic Acid; Stomach Diseases; Stomach Ulcer

2000
Cyclooxygenase-independent inhibition of dendritic cell maturation by aspirin.
    Immunology, 2000, Volume: 101, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Culture Techniques; Cell Differentiation; Cyclooxygenase Inhibitors; Dendritic Cells; Dinoprostone; Humans; Interleukin-12; Lymphocyte Activation; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Salicylic Acid; T-Lymphocytes

2000
Determination of salicylate hydroxylation products as an in vivo oxidative stress marker.
    Free radical biology & medicine, 2000, Volume: 29, Issue:11

    Topics: Adult; Aspirin; Biomarkers; Chromatography, High Pressure Liquid; Humans; Hydroxybenzoates; Hydroxyl Radical; Hydroxylation; Oxidative Stress; Salicylic Acid; Sensitivity and Specificity

2000
The solvent shells of cluster ions produced by direct electric field extraction from glycerol/water mixtures.
    Rapid communications in mass spectrometry : RCM, 2001, Volume: 15, Issue:7

    Topics: Algorithms; Amino Acids; Ascorbic Acid; Aspartic Acid; Aspirin; Glutamic Acid; Glycerol; Hydrocarbons, Halogenated; Ions; Membranes; Models, Theoretical; Molecular Structure; Niacin; Salicylic Acid; Spectrometry, Mass, Electrospray Ionization; Water

2001
Non-ionic micellar affinity capillary electrophoresis for analysis of interactions between micelles and drugs.
    Journal of pharmaceutical and biomedical analysis, 2001, Volume: 24, Issue:4

    Topics: Aspirin; Benzoic Acid; Chromatography, Micellar Electrokinetic Capillary; Hydroxybenzoates; Micelles; Picrates; Salicylic Acid

2001
Direct toxicity of nonsteroidal antiinflammatory drugs for renal medullary cells.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Apr-24, Volume: 98, Issue:9

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Aspirin; Caffeine; Cell Division; Cell Line; Cyclooxygenase Inhibitors; Drug Interactions; Flow Cytometry; Indomethacin; Kidney Tubules, Collecting; Mice; Microscopy, Electron; Salicylic Acid

2001
Salicylic acid in the serum of subjects not taking aspirin. Comparison of salicylic acid concentrations in the serum of vegetarians, non-vegetarians, and patients taking low dose aspirin.
    Journal of clinical pathology, 2001, Volume: 54, Issue:7

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromatography, High Pressure Liquid; Diet, Vegetarian; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Salicylic Acid

2001
[Research on the separation behavior of acidic drugs in capillary electrophoresis with reversed direction of electroosmotic flow].
    Se pu = Chinese journal of chromatography, 1998, Volume: 16, Issue:5

    Topics: Aspirin; Cetrimonium; Cetrimonium Compounds; Electrophoresis, Capillary; Salicylic Acid; Surface-Active Agents

1998
Collective vibrational modes in biological molecules investigated by terahertz time-domain spectroscopy.
    Biopolymers, 2002, Volume: 67, Issue:4-5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoic Acid; Hydroxybenzoates; Parabens; Protein Conformation; Salicylic Acid; Spectrophotometry; Temperature; Time Factors

2002
Zeta-crystallin displays strong selectivity for salicylic acid over aspirin.
    Biochemical and biophysical research communications, 2002, Apr-26, Volume: 293, Issue:1

    Topics: Animals; Aspirin; Camelus; Crystallins; Kinetics; NADP; Salicylic Acid; Spectrometry, Fluorescence

2002
Endogenous salicylates, aspirin, and inflammation.
    Archives of internal medicine, 2002, Jul-08, Volume: 162, Issue:13

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers; C-Reactive Protein; Humans; Inflammation; Salicylic Acid

2002
Prevention by parenteral aspirin of indomethacin-induced gastric lesions in rats: mediation by salicylic acid.
    Digestive diseases and sciences, 2002, Volume: 47, Issue:7

    Topics: Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastric Mucosa; Gastrointestinal Motility; Indomethacin; Injections, Subcutaneous; Male; Rats; Rats, Sprague-Dawley; Salicylic Acid

2002
Surface-enhanced Raman scattering of some water insoluble drugs in silver hydrosols.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2003, Volume: 59, Issue:3

    Topics: Acetaminophen; Aspirin; Pharmaceutical Preparations; Powders; Salicylic Acid; Silver; Solubility; Spectrum Analysis, Raman; Surface Properties; Tretinoin; Water

2003
[Determination of aspirin and free salicylic acid in lysinipirine injection by high performance liquid chromatography].
    Se pu = Chinese journal of chromatography, 2002, Volume: 20, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Calibration; Chromatography, High Pressure Liquid; Lysine; Salicylic Acid

2002
Non-prostaglandin effects of aspirin III and salicylate: inhibition of integrin-dependent human neutrophil aggregation and inflammation in COX 2- and NF kappa B (P105)-knockout mice.
    Advances in experimental medicine and biology, 2002, Volume: 507

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Aggregation; Cyclooxygenase 2; Humans; Integrins; Isoenzymes; Membrane Proteins; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Neutrophils; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Salicylic Acid

2002
[Separation of salicylic acid drugs by aqueous and nonaqueous capillary electrophoresis with conductance detector].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2003, Volume: 38, Issue:3

    Topics: Aspirin; Benzenesulfonates; Electrophoresis, Capillary; Ethanol; Salicylates; Salicylic Acid; Sensitivity and Specificity; Tablets; Water

2003
Determination of free salicylic acid in chewing aspirin tablets by HPLC.
    Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2003, Volume: 23, Issue:7

    Topics: Aspirin; Chromatography, High Pressure Liquid; Drug Stability; Mastication; Salicylic Acid; Tablets

2003
Investigation of some complexes formed in solution by caffeine. III. Interactions between caffeine and aspirin, p-hydroxybenzoic acid, m-hydroxybenzoic acid, salicylic acid, salicylate ion, and butyl paraben.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1953, Volume: 42, Issue:3

    Topics: Aspirin; Benzoates; Caffeine; Hydroxybenzoates; Parabens; Pharmaceutical Solutions; Salicylates; Salicylic Acid; Solutions

1953
Some recent advances in the pharmacology of salicylates.
    The Journal of pharmacy and pharmacology, 1953, Volume: 5, Issue:2

    Topics: Aspirin; Salicylates; Salicylic Acid

1953
Spectrophotometric determination of acetylsalicylic and salicylic acids.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1954, Volume: 43, Issue:5

    Topics: Aspirin; Salicylates; Salicylic Acid; Spectrophotometry

1954
Investigation of complexes formed in solution by caffeine. VI. Comparison of complexing behaviors of methylated xanthines with p-aminobenzoic acid, salicylic acid, acetylsalicylic acid, and p-hydroxybenzoic acid.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1954, Volume: 43, Issue:9

    Topics: 4-Aminobenzoic Acid; Aspirin; Benzoates; Caffeine; Hydroxybenzoates; Pharmaceutical Solutions; Salicylic Acid; Solutions; Theobromine; Theophylline; Xanthines

1954
[Gastrointestinal hemorrhage after salicylic acid therapy in peptic ulcer of long duration].
    Praxis, 1955, Sep-15, Volume: 44, Issue:37

    Topics: Aspirin; Gastrointestinal Hemorrhage; Humans; Melena; Peptic Ulcer; Salicylic Acid

1955
The hydrolysis of aspirin in pharmaceutical preparations; a limit test for free salicylic acid.
    The Journal of pharmacy and pharmacology, 1955, Volume: 7, Issue:11

    Topics: Aspirin; Humans; Hydrolysis; Salicylic Acid

1955
The effect of salicylic acid and acetylsalicylic acid on uric acid excretion and plasma uric acid concentration in the normal human subject.
    Acta pharmacologica et toxicologica, 1955, Volume: 11, Issue:4

    Topics: Aspirin; Blood; Body Fluids; Humans; Salicylic Acid; Uric Acid; Urine

1955
[Metabolic studies on drugs. II. Metabolic products of salicylic, acetylsalicylic, gentisic, and salicyluric acids in rat urine].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1957, Feb-05, Volume: 306, Issue:4-6

    Topics: Animals; Aspirin; Biochemical Phenomena; Gentisates; Hippurates; Rats; Salicylates; Salicylic Acid; Uric Acid

1957
[Contribution to the treatment of rheumatism diseases with a para-aminobenzoic acid-salicylic combination A 55].
    Deutsches medizinisches Journal, 1958, Volume: 9, Issue:4

    Topics: 4-Aminobenzoic Acid; Aspirin; Phenacetin; Rheumatic Diseases; Salicylamides; Salicylic Acid

1958
A study of the oxidative metabolism of acetylsalicylic, salicylic, and gentisic acid in fevered animals.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1958, Volume: 47, Issue:8

    Topics: Animals; Aspirin; Fever; Gentisates; Salicylates; Salicylic Acid

1958
[Cortico-salicylic therapy of chronic rheumatic diseases].
    Prensa medica argentina, 1958, Feb-14, Volume: 45, Issue:7

    Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Humans; Prednisone; Rheumatic Diseases; Salicylic Acid

1958
[Proposals for the DAB 7. 6. Acetanilid, acetylsalicylic acid, salicylic acid, sodium salicylate].
    Pharmazeutische Zentralhalle fur Deutschland, 1959, Volume: 98

    Topics: Acetanilides; Aspirin; Salicylates; Salicylic Acid; Sodium Salicylate

1959
[Comparative toxicity of salicylic acid in the white mouse].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1959, Volume: 153

    Topics: Animals; Aspirin; Mice; Salicylic Acid

1959
[Detection methods for the active constituents of antineuralgia and sleeping tablets separated by thinlayer chromatography].
    Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1963, Volume: 296/68

    Topics: Antipyrine; Aspirin; Benzoates; Chromatography, Thin Layer; Codeine; Hypnotics and Sedatives; Noscapine; Phenacetin; Salicylamides; Salicylic Acid; Sleep; Tablets

1963
[On the mechanism of action of salicylic acid, acetylsalicylic acid and salicylamide].
    Zeitschrift fur Rheumaforschung, 1963, Volume: 22

    Topics: Aspirin; Salicylamides; Salicylates; Salicylic Acid

1963
"Alka-seltzer" and haematemesis.
    British medical journal, 1963, Feb-02, Volume: 1, Issue:5326

    Topics: Aspirin; Citrates; Drug Combinations; Hematemesis; Humans; Salicylic Acid; Sodium Bicarbonate

1963
[Evaluation of the behavior of the erythrocyte sedimentation rate during salicylic therapy. II. The changes in sedimentometry during salicylic therapy or rneumatic disease].
    Bollettino della Societa italiana di cardiologia, 1962, Volume: 7

    Topics: Aspirin; Blood Sedimentation; Hematologic Tests; Humans; Rheumatic Heart Disease; Salicylic Acid; Sodium Salicylate

1962
"SALICYLURIA"--A RECAPITULATION.
    Medicine, science, and the law, 1964, Volume: 4

    Topics: Aspirin; Chemistry Techniques, Analytical; Chlorides; Fluorescence; Humans; Iron; Salicylic Acid; Toxicology; Ultraviolet Rays; Urine; X-Ray Diffraction

1964
ANTACID AND ANTIULCER PROPERTIES OF THE POLYSACCHARIDE CHITOSAN IN THE RAT.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 115

    Topics: Antacids; Anti-Ulcer Agents; Aspirin; Blood; Carrageenan; Chitosan; Colorimetry; Gastric Acidity Determination; Glycosaminoglycans; Magnesium; Peptic Ulcer; Pharmacology; Polysaccharides; Pylorus; Rats; Research; Salicylic Acid

1964
A CLINICAL APPRAISAL OF A NEW EFFECTIVE SUSTAINED RELEASE ASPIRIN TABLET.
    The American journal of orthopedics, 1964, Volume: 6

    Topics: Analgesia; Aspirin; Biomedical Research; Blood; Body Weight; Delayed-Action Preparations; Drug Therapy; Pain Management; Rheumatic Diseases; Salicylic Acid; Tablets; Toxicology

1964
SERUM SALICYLATE LEVELS IN OSTEOARTHRITIS FOLLOWING ORAL ADMINISTRATION OF A PREPARATION CONTAINING SALICYLSALICYLIC ACID.
    The American journal of the medical sciences, 1964, Volume: 248

    Topics: Administration, Oral; Aspirin; Blood; Blood Chemical Analysis; Drug Therapy; Geriatrics; Humans; Osteoarthritis; Salicylates; Salicylic Acid

1964
[ABSORPTION OF SOME CHEMICAL SUBSTANCES BY THE GASTROINTESTINAL TRACT OF GERM-FREE AND CONVENTIONAL RATS].
    Annales pharmaceutiques francaises, 1964, Volume: 22

    Topics: 4-Aminobenzoic Acid; Aminobenzoates; Aspirin; Fasting; Gastrointestinal Tract; Germ-Free Life; Intestinal Absorption; Intestine, Small; Intestines; Perfusion; Phenols; Rats; Research; Salicylic Acid; Xylose

1964
NARCOTIC AND NON-NARCOTIC ANALGESICS WHICH BLOCK VISCERAL PAIN EVOKED BY INTRA-ARTERIAL INJECTION OF BRADYKININ AND OTHER ALGESIC AGENTS.
    Archives internationales de pharmacodynamie et de therapie, 1964, Jun-01, Volume: 149

    Topics: Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Anilides; Antipyretics; Aspirin; Bradykinin; Dogs; Injections, Intra-Arterial; Levorphanol; Meperidine; Morphine; Nalorphine; Narcotics; Oxyphenbutazone; Pain; Pharmacology; Phenylbutazone; Research; Salicylic Acid; Toxicology; Visceral Pain

1964
[LIGHT AND ELECTRON MICROSCOPIC STUDIES ON THE LOCAL EFFECT OF SOME SALICYLATES ON THE GASTROINTESTINAL MUCOSA].
    Arzneimittel-Forschung, 1964, Volume: 14

    Topics: Aspirin; Electrons; Gastrointestinal Tract; Guinea Pigs; Microscopy; Microscopy, Electron; Mucous Membrane; Pharmacology; Rats; Research; Salicylamides; Salicylates; Salicylic Acid; Toxicology

1964
TERATOGENIC ACTION OF SALICYLATES RELATED TO THE INHIBITION OF MUCOPOLYSACCHARIDE SYNTHESIS.
    Acta paediatrica Scandinavica, 1965, Volume: 54

    Topics: Abnormalities, Drug-Induced; Aspirin; Blood Vessels; Carbohydrate Metabolism; Glycosaminoglycans; Mice; Pharmacology; Pregnancy; Pregnancy, Animal; Research; Ribs; Salicylates; Salicylic Acid; Spine; Teratogens; Toxicology

1965
CHROMATOGRAPHIC METHOD FOR THE SIMULTANEOUS DETERMINATION OF ASPIRIN, CAFFEINE, AND ACETAMINOPHEN.
    Journal of pharmaceutical sciences, 1964, Volume: 53

    Topics: Acetaminophen; Aspirin; Caffeine; Chemistry, Pharmaceutical; Chromatography; Pharmacy; Research; Salicylic Acid

1964
INTERACTION BETWEEN POLY-N-VINYL-5-METHYL-2-OXAZOLIDINONE AND CERTAIN PHARMACEUTICALS IN AQUEOUS SOLUTION.
    Journal of pharmaceutical sciences, 1965, Volume: 54

    Topics: Aspirin; Barbiturates; Benzoates; Chemistry, Pharmaceutical; Cimetidine; Diphenhydramine; Drug Combinations; Ibuprofen; Indoles; Ketanserin; Macromolecular Substances; Methylprednisolone; Oxazoles; Oxazolidinones; Polymers; Research; Salicylic Acid; Sulfonamides; Xanthines

1965
A KINETIC STUDY OF THE ELIMINATION OF SALICYLATE IN MAN.
    British journal of pharmacology and chemotherapy, 1965, Volume: 24

    Topics: Aspirin; Biological Transport; Body Fluids; Fluids and Secretions; Humans; Kinetics; Male; Metabolism; Research; Salicylates; Salicylic Acid; Urine

1965
DAMAGE TO THE GASTRIC MUCOSA: EFFECTS OF SALICYLATES AND STIMULATION.
    Gastroenterology, 1965, Volume: 49

    Topics: Absorption; Animals; Aspirin; Bethanechol Compounds; Denervation; Dogs; Gastric Mucosa; Gastrins; Gastrointestinal Hemorrhage; Hemorrhage; Histamine; Intestinal Absorption; Ion Exchange; Pharmacology; Research; Salicylates; Salicylic Acid; Sympathomimetics; Toxicology

1965
A rapid high-performance liquid chromatographic method for the simultaneous quantitation of aspirin, salicylic acid, and caffeine in effervescent tablets.
    Journal of chromatographic science, 2003, Volume: 41, Issue:8

    Topics: Aspirin; Caffeine; Chromatography, High Pressure Liquid; Reference Standards; Reproducibility of Results; Salicylic Acid; Sensitivity and Specificity; Tablets

2003
Antioxidant effect of acetylsalicylic and salicylic acid in rat brain slices subjected to hypoxia.
    Journal of neuroscience research, 2004, Jan-15, Volume: 75, Issue:2

    Topics: Animals; Aspirin; Cell Death; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Glutathione; Hypoxia, Brain; In Vitro Techniques; Lipid Peroxidation; Male; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Wistar; Salicylic Acid

2004
Comparative pharmacokinetics of acetyl salicylic acid and its metabolites in children suffering from autoimmune diseases.
    Biopharmaceutics & drug disposition, 2004, Volume: 25, Issue:1

    Topics: Administration, Oral; Adolescent; Area Under Curve; Arthritis, Juvenile; Aspirin; Autoimmune Diseases; Biological Availability; Child; Chromatography, High Pressure Liquid; Female; Gentisates; Half-Life; Hippurates; Humans; Male; Mexico; Prospective Studies; Rheumatic Fever; Salicylic Acid; Tablets

2004
[Study on relative bioavailability of aspirin in afenca tablet].
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2003, Volume: 20, Issue:4

    Topics: Administration, Oral; Adult; Area Under Curve; Aspirin; Cross-Over Studies; Humans; Male; Salicylic Acid; Tablets; Therapeutic Equivalency

2003
[Aspirin and salicylates; present view of their biological effect].
    Gazette medicale de France, 1951, Volume: 58, Issue:7

    Topics: Aspirin; Humans; Salicylates; Salicylic Acid

1951
The synthesis of acetyl-1-C14-salicylic acid.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1951, Volume: 40, Issue:10

    Topics: Aspirin; Radioisotopes; Salicylic Acid

1951
Antioxidant effects of a single dose of acetylsalicylic acid and salicylic acid in rat brain slices subjected to oxygen-glucose deprivation in relation with its antiplatelet effect.
    Neuroscience letters, 2004, Apr-01, Volume: 358, Issue:3

    Topics: Animals; Antioxidants; Aspirin; Cell Hypoxia; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Glucose; Glutathione; Hypoxia-Ischemia, Brain; In Vitro Techniques; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Oxidative Stress; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Salicylic Acid

2004
[Development of salicylic acid detector tube].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2004, Volume: 17, Issue:2

    Topics: Acute Disease; Aspirin; Biomarkers; Humans; Poisoning; Reagent Kits, Diagnostic; Salicylic Acid; Toxicology

2004
Life-history traits of standard and autochthonous cladocerans: II. Acute and chronic effects of acetylsalicylic acid metabolites.
    Environmental toxicology, 2004, Volume: 19, Issue:5

    Topics: Animals; Aspirin; Cladocera; Daphnia; Female; Fresh Water; Gentisates; Hippurates; Male; No-Observed-Adverse-Effect Level; Portugal; Reproduction; Salicylic Acid; Toxicity Tests, Acute; Toxicity Tests, Chronic; Water Pollutants, Chemical

2004
MORNING STIFFNESS IN ARTHRITIS.
    Clinical medicine (Northfield, Ill.), 1963, Volume: 70

    Topics: Arthritis; Arthritis, Rheumatoid; Aspirin; Humans; Joint Diseases; Nervous System Diseases; Placebos; Salicylic Acid

1963
HucR, a novel uric acid-responsive member of the MarR family of transcriptional regulators from Deinococcus radiodurans.
    The Journal of biological chemistry, 2004, Dec-03, Volume: 279, Issue:49

    Topics: Amino Acid Sequence; Aspirin; Binding Sites; Circular Dichroism; Cloning, Molecular; Deinococcus; Deoxyribonuclease I; DNA; DNA, Intergenic; Dose-Response Relationship, Drug; Edetic Acid; Escherichia coli Proteins; Gene Expression Regulation; Kinetics; Ligands; Models, Chemical; Models, Genetic; Molecular Sequence Data; Open Reading Frames; Oxidative Stress; Phenol; Promoter Regions, Genetic; Protein Binding; Reactive Oxygen Species; Repressor Proteins; RNA; RNA, Messenger; Salicylic Acid; Sequence Homology, Amino Acid; Temperature; Transcription Factors; Transcription, Genetic; Urate Oxidase; Uric Acid

2004
Inhibition of cardiac mitochondrial respiration by salicylic acid and acetylsalicylate.
    Journal of cardiovascular pharmacology, 2004, Volume: 44, Issue:5

    Topics: Animals; Aspirin; Cell Respiration; Citric Acid Cycle; Dinitrophenols; Drug Evaluation, Preclinical; Electron Transport; Ketoglutarate Dehydrogenase Complex; Mitochondria, Heart; NAD; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Salicylic Acid; Sarcolemma; Uncoupling Agents

2004
Salicylate inhibition of rat mammary carcinogenesis and angiogenesis in female rat compatible with misoprostol administration.
    International journal of oncology, 2005, Volume: 26, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Transformation, Neoplastic; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Animal; Misoprostol; Neovascularization, Pathologic; Oxytocics; Rats; Rats, Sprague-Dawley; Salicylic Acid

2005
Aspirin down-regulates tryptophan degradation in stimulated human peripheral blood mononuclear cells in vitro.
    Clinical and experimental immunology, 2005, Volume: 140, Issue:1

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cells, Cultured; Concanavalin A; Down-Regulation; Humans; Kynurenine; Leukocytes, Mononuclear; Neopterin; Phytohemagglutinins; Protein Denaturation; Salicylic Acid; Tryptophan

2005
Production of antioxidant compounds by culture of Panax ginseng C.A. Meyer hairy roots: I. Enhanced production of secondary metabolite in hairy root cultures by elicitation.
    Applied biochemistry and biotechnology, 2005,Spring, Volume: 121-124

    Topics: Antioxidants; Aspirin; Cell Culture Techniques; Cell Proliferation; Dose-Response Relationship, Drug; Panax; Plant Roots; Rhizobium; Salicylates; Salicylic Acid; Saponins; Yeasts

2005
Glucuronidation of the aspirin metabolite salicylic acid by expressed UDP-glucuronosyltransferases and human liver microsomes.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Glucuronides; Glucuronosyltransferase; Humans; Microsomes, Liver; Salicylic Acid

2006
Mechanism of action of novel NO-releasing furoxan derivatives of aspirin in human platelets.
    British journal of pharmacology, 2006, Volume: 148, Issue:4

    Topics: Adult; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Humans; Middle Aged; Nitric Oxide; Nitric Oxide Donors; Oxadiazoles; Platelet Aggregation; Salicylic Acid

2006
Aspirin is a substrate for paraoxonase-like activity: implications in atherosclerosis.
    Atherosclerosis, 2007, Volume: 191, Issue:2

    Topics: Adult; Antioxidants; Aryldialkylphosphatase; Aspirin; Atherosclerosis; Binding, Competitive; Biotransformation; Humans; Hydrolysis; In Vitro Techniques; Nitrophenols; Paraoxon; Platelet Aggregation Inhibitors; Salicylic Acid

2007
Influence of water-cellulose binding energy on stability of acetylsalicylic acid.
    International journal of pharmaceutics, 2006, Oct-12, Volume: 323, Issue:1-2

    Topics: Aspirin; Calorimetry, Differential Scanning; Cellulose; Drug Stability; Excipients; Kinetics; Microscopy, Electron, Scanning; Salicylic Acid; Temperature; Thermodynamics; Water; X-Ray Diffraction

2006
Therapeutic levels of aspirin and salicylate directly inhibit a model of angiogenesis through a Cox-independent mechanism.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:12

    Topics: Antineoplastic Agents; Aspirin; Celecoxib; Cell Line; Cell Proliferation; Cell Survival; Cyclooxygenase Inhibitors; Endothelial Cells; Humans; Neovascularization, Physiologic; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Salicylic Acid; Sulfonamides

2006
Semi-micro column high-performance liquid chromatography with UV detection for quantification of aspirin and salicylic acid and its application to patients' sera administered with low-dose enteric-coated aspirin.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:3

    Topics: Aged; Aged, 80 and over; Aspirin; Chromatography, High Pressure Liquid; Female; Humans; Indicators and Reagents; Male; Middle Aged; Salicylic Acid; Solid Phase Extraction; Spectrophotometry, Ultraviolet; Tablets, Enteric-Coated

2007
Derivative-ratio spectrophotometric method for the determination of ternary mixture of aspirin, paracetamol and salicylic acid.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2007, Volume: 68, Issue:2

    Topics: Acetaminophen; Aspirin; Drug Combinations; Salicylic Acid; Spectrophotometry; Spectrophotometry, Ultraviolet

2007
Samuel James (c1763-1831) of Hoddesdon and the medicinal use of willow bark.
    Journal of medical biography, 2007, Volume: 15, Issue:1

    Topics: Aspirin; Chemistry, Analytic; England; History, 18th Century; History, 19th Century; Humans; Pain; Plant Bark; Plant Extracts; Salicylic Acid; Salix

2007
Potentiometric response and mechanism of anionic recognition of heterocalixarene-based ion selective electrodes.
    Analytica chimica acta, 2007, Mar-28, Volume: 587, Issue:2

    Topics: Anions; Aspirin; Binding Sites; Calixarenes; Chemistry Techniques, Analytical; Hydrogen Bonding; Hydrogen-Ion Concentration; Ion-Selective Electrodes; Ions; Models, Chemical; Polymers; Potentiometry; Salicylic Acid

2007
The study of the influence of surfactant charge on alkaline hydrolysis reactions of acetylsalicylic acid (ASA) and triflusal (TFL) using spectrophotometric methods.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2007, Volume: 31, Issue:3-4

    Topics: Algorithms; Alkalies; Aspirin; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Platelet Aggregation Inhibitors; Polyethylene Glycols; Quaternary Ammonium Compounds; Salicylates; Salicylic Acid; Sodium Dodecyl Sulfate; Sodium Hydroxide; Spectrophotometry, Ultraviolet; Static Electricity; Surface-Active Agents; Water

2007
Generalized regression neural networks in prediction of drug stability.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Compounding; Drug Design; Drug Stability; Drug Storage; Hardness; Neural Networks, Computer; Polymethacrylic Acids; Salicylic Acid; Tablets; Temperature

2007
Gallic acid, a dietary polyphenolic component, blunts the inhibition of platelet COX-1 by aspirin: preliminary in-vitro findings.
    Thrombosis and haemostasis, 2007, Volume: 97, Issue:6

    Topics: Aspirin; Blood Platelets; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Food-Drug Interactions; Gallic Acid; Humans; In Vitro Techniques; Platelet Aggregation; Salicylic Acid; Thromboxane B2

2007
In vitro enantioselective displacement of propranolol from protein binding sites by acetyl salicylic acid and salicylic acid.
    International journal of pharmaceutics, 2007, Sep-05, Volume: 342, Issue:1-2

    Topics: Adrenergic beta-Antagonists; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding, Competitive; Blood Proteins; Drug Interactions; Humans; Kinetics; Propranolol; Protein Binding; Salicylic Acid; Serum Albumin; Stereoisomerism

2007
Differences in the influence of the interaction between acetylsalicylic acid and salicylic acid on platelet function in whole blood and isolated platelets: influence of neutrophils.
    Pharmacological research, 2007, Volume: 56, Issue:2

    Topics: Adult; Aspirin; Blood Platelets; Dose-Response Relationship, Drug; Drug Interactions; Humans; In Vitro Techniques; Male; Neutrophils; Nitric Oxide; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Salicylic Acid; Thromboxane B2

2007
[Autopsy case of aspirin intoxication: distribution of salicylic acid and salicyluric acid in body fluid and organs].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2007, Volume: 20, Issue:4

    Topics: Aspirin; Autopsy; Body Fluids; Brain Chemistry; Chromatography, High Pressure Liquid; Female; Hippurates; Humans; Kidney; Liver; Lung; Middle Aged; Myocardium; Salicylic Acid; Tissue Distribution

2007
[From the willow to aspirin].
    Revue d'histoire de la pharmacie, 2007, Volume: 55, Issue:354

    Topics: Aspirin; Chemistry; History of Pharmacy; History, 18th Century; History, 19th Century; History, 20th Century; Humans; Molecular Structure; Salicylic Acid; Salix

2007
Determination of acetylsalicylic acid and its major metabolite, salicylic acid, in human plasma using liquid chromatography-tandem mass spectrometry: application to pharmacokinetic study of Astrix in Korean healthy volunteers.
    Biomedical chromatography : BMC, 2008, Volume: 22, Issue:6

    Topics: Aspirin; Humans; Korea; Reference Standards; Reference Values; Reproducibility of Results; Salicylic Acid; Sensitivity and Specificity; Tandem Mass Spectrometry

2008
Narrow-line waveguide terahertz time-domain spectroscopy of aspirin and aspirin precursors.
    Applied spectroscopy, 2008, Volume: 62, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzoic Acid; Hydroxybenzoates; Microwaves; Parabens; Radio Waves; Salicylic Acid; Spectrum Analysis

2008
Determination of caffeine and associated compounds in food, beverages, natural products, pharmaceuticals, and cosmetics by micellar electrokinetic capillary chromatography.
    Journal of chromatographic science, 2008, Volume: 46, Issue:2

    Topics: Acetaminophen; Antipyrine; Aspirin; Beverages; Biological Products; Caffeine; Chromatography, Micellar Electrokinetic Capillary; Codeine; Cosmetics; Food Analysis; Linear Models; Pharmaceutical Preparations; Salicylic Acid; Theobromine; Theophylline

2008
Aspirin: expectations and limitations.
    The Journal of the Association of Physicians of India, 2008, Volume: 56

    Topics: Asia, Western; Aspirin; Coronary Artery Disease; Cross-Sectional Studies; Cyclooxygenase Inhibitors; Developing Countries; Dose-Response Relationship, Drug; Drug Resistance; Ethnicity; Humans; India; Long-Term Care; Platelet Activation; Platelet Aggregation Inhibitors; Salicylic Acid; Tablets, Enteric-Coated; Treatment Outcome

2008
Pharmacokinetic and pharmacodynamic study of NO-donating aspirin in F344 rats.
    International journal of oncology, 2008, Volume: 33, Issue:4

    Topics: Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colon; Drug Evaluation, Preclinical; Eicosanoids; Male; Nitric Oxide; Rats; Rats, Inbred F344; Salicylic Acid; Thromboxane B2; Time Factors

2008
Acetylsalicylic acid and salicylic acid decrease tumor cell viability and glucose metabolism modulating 6-phosphofructo-1-kinase structure and activity.
    Biochemical pharmacology, 2009, Jan-01, Volume: 77, Issue:1

    Topics: Animals; Aspirin; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Glucose; Humans; Phosphofructokinase-1; Protein Structure, Quaternary; Rabbits; Salicylic Acid; Structure-Activity Relationship

2009
Salicylic acid sans aspirin in animals and man: persistence in fasting and biosynthesis from benzoic acid.
    Journal of agricultural and food chemistry, 2008, Dec-24, Volume: 56, Issue:24

    Topics: Adult; Animals; Aspirin; Benzoic Acid; Fasting; Female; Hippurates; Humans; Male; Middle Aged; Salicylic Acid

2008
A comparison of salicylic acid levels in normal subjects after rectal versus oral dosing.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009, Volume: 16, Issue:2

    Topics: Administration, Oral; Administration, Rectal; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Emergency Service, Hospital; Female; Humans; Male; Middle Aged; Prospective Studies; Salicylic Acid; Suppositories

2009
Effects of acetylsalicylic acid on increase of fibrin network porosity and the consequent upregulation of fibrinolysis.
    Journal of cardiovascular pharmacology, 2009, Volume: 53, Issue:1

    Topics: Aspirin; Blood Coagulation; Blood Coagulation Tests; Blood Platelets; Fibrin; Fibrinogen; Fibrinolysis; Gels; Humans; Permeability; Porosity; Salicylic Acid; Thrombin; Up-Regulation

2009
Emergent aspirin use in cardiovascular disease in the emergency department: oral dosing versus rectal suppositories.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2009, Volume: 16, Issue:2

    Topics: Administration, Oral; Administration, Rectal; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Emergency Service, Hospital; Humans; Mastication; Salicylic Acid; Suppositories

2009
Effect of genetic polymorphisms in UDP-glucuronosyltransferase 1A6 (UGT1A6) on acetylsalicylic acid metabolism in healthy female volunteers.
    Pharmacology, 2009, Volume: 83, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Female; Glucuronosyltransferase; Hippurates; Homozygote; Humans; Polymorphism, Genetic; Salicylic Acid; Young Adult

2009
Rapid and sensitive determination of acetylsalicylic acid and salicylic acid in plasma using liquid chromatography-tandem mass spectrometry: application to pharmacokinetic study.
    Biomedical chromatography : BMC, 2009, Volume: 23, Issue:9

    Topics: Animals; Aspirin; Calibration; Chromatography, Liquid; Dogs; Drug Stability; Linear Models; Male; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Salicylic Acid; Sensitivity and Specificity; Tandem Mass Spectrometry

2009
Effect of analgesics and their derivatives on antibiotic resistance of environmental microbes.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2009, Volume: 59, Issue:9

    Topics: Amino Acid Sequence; Analgesics; Anti-Bacterial Agents; Aspirin; Bacterial Proteins; Ciprofloxacin; Drug Resistance, Microbial; Escherichia coli; Escherichia coli Proteins; Lipoproteins; Membrane Transport Proteins; Microbial Sensitivity Tests; Molecular Sequence Data; Nalidixic Acid; Nitrosomonas europaea; Salicylic Acid; Salmonella enterica; Sequence Homology, Amino Acid

2009
Sub-millimolar concentration of the novel phenol-based compound, 2-hydroxy benzoate zinc, induces apoptosis in human HT-1080 fibrosarcoma cells.
    Cell proliferation, 2010, Volume: 43, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Aspirin; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Fibrosarcoma; Humans; Salicylic Acid; Tumor Suppressor Protein p53

2010
Anti-inflammatory drugs selectively target sporangium development in Mucor.
    Canadian journal of microbiology, 2009, Volume: 55, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Aspirin; Benzoic Acid; Ibuprofen; Indomethacin; Mitochondria; Mortierella; Mucor; Mucormycosis; Plant Diseases; Salicylic Acid

2009
Development and validation of a high-performance liquid chromatography method for the simultaneous determination of aspirin and folic acid from nano-particulate systems.
    Biomedical chromatography : BMC, 2010, Volume: 24, Issue:9

    Topics: Aspirin; Chromatography, High Pressure Liquid; Folic Acid; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Reproducibility of Results; Salicylic Acid

2010
In search of pure liquid salt forms of aspirin: ionic liquid approaches with acetylsalicylic acid and salicylic acid.
    Physical chemistry chemical physics : PCCP, 2010, Feb-28, Volume: 12, Issue:8

    Topics: Aspirin; Crystallography, X-Ray; Hydrogen Bonding; Hydrolysis; Ionic Liquids; Phase Transition; Salicylic Acid; Salts; Transition Temperature

2010
Electrochemical behavior of triflusal, aspirin and their metabolites at glassy carbon and boron doped diamond electrodes.
    Combinatorial chemistry & high throughput screening, 2010, Volume: 13, Issue:7

    Topics: Alkalies; Aspirin; Boron; Carbon; Diamond; Electrochemistry; Electrodes; Glass; High-Throughput Screening Assays; Hydrogen-Ion Concentration; Hydrolysis; Molecular Structure; Particle Size; Salicylates; Salicylic Acid; Surface Properties; Water

2010
Two cases of oral aspirin overdose.
    Journal of forensic and legal medicine, 2010, Volume: 17, Issue:5

    Topics: Administration, Oral; Adult; Aspirin; Chromatography, High Pressure Liquid; Diphenhydramine; Drug Overdose; Female; Forensic Pathology; Forensic Toxicology; Gastrointestinal Contents; Humans; Hypnotics and Sedatives; Japan; Male; Platelet Aggregation Inhibitors; Salicylic Acid; Suicide

2010
Study of inhibitors of the PGH synthases for which potency is regulated by the redox state of the enzymes.
    Methods in molecular biology (Clifton, N.J.), 2010, Volume: 644

    Topics: Acetaminophen; Animals; Arachidonic Acid; Aspirin; Blood Platelets; Cell Line, Tumor; Cyclooxygenase Inhibitors; Dinoprostone; Gas Chromatography-Mass Spectrometry; Humans; Hydrogen Peroxide; Mice; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Salicylic Acid; Thromboxane B2

2010
Para-carboxy modified amphiphilic calixarene, self-assembly and interactions with pharmaceutically-relevant molecules.
    Chimia, 2010, Volume: 64, Issue:1-2

    Topics: Acetaminophen; Aspirin; Calixarenes; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Molecular Structure; Nanoparticles; Particle Size; Salicylic Acid; Surface Properties; Surface-Active Agents; Unilamellar Liposomes

2010
Willow species and aspirin: different mechanism of actions.
    Phytotherapy research : PTR, 2011, Volume: 25, Issue:7

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Benzyl Alcohols; Flavonoids; Glucosides; Humans; Plant Bark; Polyphenols; Salicylic Acid; Salix; Species Specificity

2011
DNA immobilization on a polypyrrole nanofiber modified electrode and its interaction with salicylic acid/aspirin.
    Analytical biochemistry, 2011, Apr-15, Volume: 411, Issue:2

    Topics: Animals; Aspirin; Cattle; Dielectric Spectroscopy; DNA; Electrochemical Techniques; Electrodes; Guanine; Nanofibers; Oxidation-Reduction; Polymers; Pyrroles; Salicylic Acid

2011
Electrocatalytic oxidation of salicylic acid by a cobalt hydrotalcite-like compound modified Pt electrode.
    Biosensors & bioelectronics, 2011, Mar-15, Volume: 26, Issue:7

    Topics: Aluminum Hydroxide; Aspirin; Catalysis; Cobalt; Drug Contamination; Electrochemical Techniques; Electrodes; Magnesium Hydroxide; Oxidation-Reduction; Platinum; Salicylic Acid; Sensitivity and Specificity

2011
Nitrooxyacyl derivatives of salicylic acid: aspirin-like molecules that covalently inactivate cyclooxygenase-1.
    ChemMedChem, 2011, Mar-07, Volume: 6, Issue:3

    Topics: Anti-Inflammatory Agents; Aspirin; Catalytic Domain; Cell Line; Computer Simulation; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Humans; Platelet Aggregation Inhibitors; Recombinant Proteins; Salicylic Acid

2011
Two novel aspirin analogues show selective cytotoxicity in primary chronic lymphocytic leukaemia cells that is associated with dual inhibition of Rel A and COX-2.
    Cell proliferation, 2011, Volume: 44, Issue:4

    Topics: ADP-ribosyl Cyclase 1; Aged; Animals; Antineoplastic Agents; Apoptosis; Aspirin; Caspase 3; Caspase Inhibitors; CD40 Antigens; Coculture Techniques; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Membrane Glycoproteins; Mice; Oligopeptides; Parabens; Salicylic Acid; Transcription Factor RelA; Transcription, Genetic; Tumor Cells, Cultured; ZAP-70 Protein-Tyrosine Kinase

2011
Method development and validation for optimised separation of salicylic, acetyl salicylic and ascorbic acid in pharmaceutical formulations by hydrophilic interaction chromatography and response surface methodology.
    Journal of chromatography. A, 2011, Sep-02, Volume: 1218, Issue:35

    Topics: Acetates; Acetonitriles; Analysis of Variance; Ascorbic Acid; Aspirin; Chromatography, Liquid; Drug Contamination; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Least-Squares Analysis; Models, Chemical; Reproducibility of Results; Salicylic Acid; Sensitivity and Specificity; Tablets; Temperature

2011
Aspirin extrusion from human platelets through multidrug resistance protein-4-mediated transport: evidence of a reduced drug action in patients after coronary artery bypass grafting.
    Journal of the American College of Cardiology, 2011, Aug-09, Volume: 58, Issue:7

    Topics: Adult; Aspirin; Biological Transport; Blood Platelets; Cells, Cultured; Coronary Artery Bypass; Cyclic AMP; Cyclooxygenase 1; Dinoprostone; Drug Interactions; Drug Resistance; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Platelet Aggregation; Platelet Aggregation Inhibitors; Propionates; Prostaglandin-Endoperoxide Synthases; Quinolines; RNA, Small Interfering; Salicylic Acid; Thromboxane B2

2011
Nanostructured conducting molecularly imprinted polymer for selective extraction of salicylate from urine and serum samples by electrochemically controlled solid-phase micro-extraction.
    Analytica chimica acta, 2011, Nov-30, Volume: 707, Issue:1-2

    Topics: Administration, Oral; Animals; Aspirin; Cattle; Electrochemistry; Humans; Molecular Imprinting; Nanostructures; Salicylic Acid; Solid Phase Extraction

2011
Simultaneous determination and pharmacokinetics of protein unbound aspirin and salicylic acid in rat blood and brain by microdialysis: an application to herbal-drug interaction.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, May-01, Volume: 895-896

    Topics: Animals; Area Under Curve; Aspirin; Bleeding Time; Brain Chemistry; Drug Stability; Drugs, Chinese Herbal; Herb-Drug Interactions; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Salicylic Acid

2012
Aspirin downregulates angiotensin type 1 receptor transcription implications in capillary formation from endothelial cells.
    Journal of cardiovascular pharmacology, 2012, Volume: 60, Issue:2

    Topics: Angiogenesis Inhibitors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Aspirin; Capillaries; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Losartan; Mitogen-Activated Protein Kinases; NADPH Oxidases; Neovascularization, Physiologic; Receptor, Angiotensin, Type 1; RNA, Messenger; Salicylic Acid; Transcription, Genetic; Vascular Endothelial Growth Factor A

2012
Preparation of lipid aspirin sustained-release pellets by solvent-free extrusion/spheronization and an investigation of their stability.
    Drug development and industrial pharmacy, 2012, Volume: 38, Issue:10

    Topics: Aspirin; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Implants; Drug Stability; Lipids; Microscopy, Electron, Scanning; Salicylic Acid; Solubility; Solvents; Technology, Pharmaceutical; Transition Temperature; X-Ray Diffraction

2012
Pharmacokinetic and pharmacodynamic interaction of Danshen-Gegen extract with warfarin and aspirin.
    Journal of ethnopharmacology, 2012, Sep-28, Volume: 143, Issue:2

    Topics: Animals; Anticoagulants; Area Under Curve; Aspirin; Drugs, Chinese Herbal; Herb-Drug Interactions; Lactates; Male; Prothrombin Time; Rats; Rats, Sprague-Dawley; Salicylic Acid; Warfarin

2012
Ibudilast, a phosphodiesterase inhibitor, in combination with low-dose aspirin potently inhibits guinea pig carotid artery thrombosis without extending bleeding time and causing gastric mucosal injury.
    Arzneimittel-Forschung, 2012, Volume: 62, Issue:12

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Bleeding Time; Carotid Artery Thrombosis; Drug Therapy, Combination; Gastric Mucosa; Guinea Pigs; Immunoenzyme Techniques; Indicators and Reagents; Male; Mice; Phosphodiesterase Inhibitors; Photochemistry; Platelet Aggregation Inhibitors; Pyridines; Rolipram; Salicylic Acid; Stomach Diseases; Thromboxane B2

2012
Low dose aspirin estimation: an application to a human pharmacokinetic study.
    Biomedical chromatography : BMC, 2013, Volume: 27, Issue:5

    Topics: Administration, Oral; Aspirin; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Stability; Humans; Limit of Detection; Male; Reproducibility of Results; Salicylic Acid; Tandem Mass Spectrometry

2013
Simultaneous determination of acetylsalicylic acid and salicylic acid in human plasma by isocratic high-pressure liquid chromatography with post-column hydrolysis and fluorescence detection.
    Biomedical chromatography : BMC, 2013, Volume: 27, Issue:6

    Topics: Aspirin; Chromatography, High Pressure Liquid; Drug Stability; Humans; Hydrolysis; Limit of Detection; Reproducibility of Results; Salicylic Acid; Spectrometry, Fluorescence

2013
Aspirin may promote mitochondrial biogenesis via the production of hydrogen peroxide and the induction of Sirtuin1/PGC-1α genes.
    European journal of pharmacology, 2013, Jan-15, Volume: 699, Issue:1-3

    Topics: Animals; Aryldialkylphosphatase; Aspirin; Cells, Cultured; Gene Expression Regulation; Heat-Shock Proteins; Hep G2 Cells; Hepatocytes; Humans; Hydrogen Peroxide; Hydroxybenzoates; Mice; Mice, Inbred C57BL; Mitochondria, Liver; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Platelet Aggregation Inhibitors; Receptors, Aryl Hydrocarbon; Salicylic Acid; Sirtuin 1; Trans-Activators; Transcription Factors

2013
Synovial distribution of "systemically" administered acetylsalicylic acid in the isolated perfused equine distal limb.
    BMC veterinary research, 2013, Mar-26, Volume: 9

    Topics: Administration, Intravenous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromatography, High Pressure Liquid; Female; Hemoperfusion; Hindlimb; Horses; Male; Microdialysis; Salicylic Acid; Synovial Fluid

2013
Association of plasma concentrations of salicylic acid and high on ASA platelet reactivity in type 2 diabetes patients.
    Cardiology journal, 2013, Volume: 20, Issue:2

    Topics: Aged; Aspirin; Biomarkers; Blood Platelets; Chromatography, High Pressure Liquid; Coronary Artery Disease; Cyclooxygenase 1; Diabetes Mellitus, Type 2; Drug Resistance; Female; Humans; Logistic Models; Male; Middle Aged; Odds Ratio; Platelet Aggregation Inhibitors; Platelet Function Tests; Poland; Predictive Value of Tests; Prospective Studies; Risk Factors; Salicylic Acid; Thromboxane B2

2013
Solid-state 17O NMR of pharmaceutical compounds: salicylic acid and aspirin.
    The journal of physical chemistry. B, 2013, Aug-22, Volume: 117, Issue:33

    Topics: Aspirin; Dimerization; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Oxygen Isotopes; Salicylic Acid; Thermodynamics

2013
Acetylsalicylic acid (aspirin) and salicylic acid interaction with the human erythrocyte membrane bilayer induce in vitro changes in the morphology of erythrocytes.
    Archives of biochemistry and biophysics, 2013, Nov-01, Volume: 539, Issue:1

    Topics: Aspirin; Cell Shape; Dimyristoylphosphatidylcholine; Erythrocyte Membrane; Humans; Lipid Bilayers; Phosphatidylethanolamines; Salicylic Acid; Unilamellar Liposomes

2013
Polysaccharide arabinogalactan from larch Larix sibirica as carrier for molecules of salicylic and acetylsalicylic acid: preparation, physicochemical and pharmacological study.
    Drug delivery, 2015, Volume: 22, Issue:3

    Topics: Administration, Oral; Animals; Aspirin; Drug Carriers; Galactans; Larix; Male; Phase Transition; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats, Wistar; Salicylic Acid; Solubility; Solutions; Surface Properties

2015
Application of time-resolved fluorescence to the determination of metabolites.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, Jul-15, Volume: 128

    Topics: Aspirin; Gentisates; Humans; Salicylic Acid; Spectrometry, Fluorescence; Urine

2014
Quality and antioxidant properties on sweet cherries as affected by preharvest salicylic and acetylsalicylic acids treatments.
    Food chemistry, 2014, Oct-01, Volume: 160

    Topics: Anthocyanins; Antioxidants; Aspirin; Fruit; Plant Extracts; Prunus; Salicylic Acid

2014
Multiple dual mode counter-current chromatography with variable duration of alternating phase elution steps.
    Journal of chromatography. A, 2014, Jun-20, Volume: 1347

    Topics: Aspirin; Caffeine; Coumarins; Countercurrent Distribution; Models, Theoretical; Salicylic Acid

2014
The adsorption of pharmaceutically active compounds from aqueous solutions onto activated carbons.
    Journal of hazardous materials, 2015, Jan-23, Volume: 282

    Topics: Adsorption; Aspirin; Atenolol; Carbon; Diclofenac; Salicylic Acid; Solutions; Surface Properties; Water Pollutants, Chemical; Water Purification

2015
Evaluation of the pharmaceutical characteristics of various enteric-coated aspirin tablets under different storage conditions.
    Chemical & pharmaceutical bulletin, 2014, Volume: 62, Issue:7

    Topics: Aspirin; Chemistry, Pharmaceutical; Drug Stability; Microscopy, Electron, Scanning; Salicylic Acid; Spectrum Analysis, Raman; Surface Properties; Tablets, Enteric-Coated; Temperature; Time Factors

2014
Modifications of the chemical structure of phenolics differentially affect physiological activities in pulvinar cells of Mimosa pudica L. I. Multimode effect on early membrane events.
    Plant physiology and biochemistry : PPB, 2014, Volume: 84

    Topics: Aspirin; Cell Membrane; Mimosa; Phenols; Proton-Translocating ATPases; Pulvinar; Salicylic Acid

2014
Aspirin may influence cellular energy status.
    European journal of pharmacology, 2015, Feb-15, Volume: 749

    Topics: Apolipoprotein A-I; Aryldialkylphosphatase; Aspirin; DNA-Binding Proteins; Hep G2 Cells; Humans; Hydrogen Peroxide; Ion Channels; Mitochondrial Proteins; NF-E2-Related Factor 2; Nitric Oxide Synthase Type III; Salicylic Acid; Sirtuins; STAT3 Transcription Factor; Transcription Factors; Uncoupling Protein 1

2015
A Reaction of Aspirin with Ferrous Gluconate.
    AAPS PharmSciTech, 2015, Volume: 16, Issue:6

    Topics: Aspirin; Ferrous Compounds; Gluconates; Iron; Oxidation-Reduction; Salicylic Acid; Solutions; Spectrophotometry

2015
Aromatic hydroxylation of salicylic acid and aspirin by human cytochromes P450.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2015, Jun-20, Volume: 73

    Topics: Aspirin; Benzaldehydes; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Deferoxamine; Enzyme Inhibitors; Humans; Hydroxylation; Isoenzymes; Microsomes, Liver; NADP; Organophosphates; Oxidation-Reduction; Reactive Oxygen Species; Recombinant Proteins; Salicylic Acid

2015
Preparation of acetylsalicylic acid-acylated chitosan as a novel polymeric drug for drug controlled release.
    International journal of biological macromolecules, 2015, Volume: 78

    Topics: Acetylation; Aspirin; Chitosan; Delayed-Action Preparations; Drug Delivery Systems; Drug Liberation; Proton Magnetic Resonance Spectroscopy; Salicylic Acid; Spectroscopy, Fourier Transform Infrared

2015
Semi-physiologic model validation and bioequivalence trials simulation to select the best analyte for acetylsalicylic acid.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2015, Jul-10, Volume: 74

    Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Biomarkers, Pharmacological; Biotransformation; Chemistry, Pharmaceutical; Computer Simulation; Dose-Response Relationship, Drug; Drug Liberation; Hippurates; Humans; Models, Biological; Pharmacology, Clinical; Salicylic Acid; Software; Therapeutic Equivalency; Tissue Distribution

2015
Isolation, Characterization of a Potential Degradation Product of Aspirin and an HPLC Method for Quantitative Estimation of Its Impurities.
    Journal of chromatographic science, 2015, Volume: 53, Issue:9

    Topics: Aspirin; Chromatography, High Pressure Liquid; Drug Contamination; Hot Temperature; Linear Models; Nuclear Magnetic Resonance, Biomolecular; Reproducibility of Results; Salicylic Acid; Sensitivity and Specificity

2015
Novel mixed metal Ag(I)-Sb(III)-metallotherapeutics of the NSAIDs, aspirin and salicylic acid: Enhancement of their solubility and bioactivity by using the surfactant CTAB.
    Journal of inorganic biochemistry, 2015, Volume: 150

    Topics: Antimony; Antineoplastic Agents; Aspirin; Cetrimonium; Cetrimonium Compounds; Coordination Complexes; Glutathione; Humans; Kinetics; Linoleic Acid; Lipoxygenase; MCF-7 Cells; Micelles; Proton Magnetic Resonance Spectroscopy; Receptors, Estrogen; Salicylic Acid; Silver; Solubility; Spectrometry, X-Ray Emission; Surface-Active Agents

2015
Complexation induced fluorescence and acid-base properties of dapoxyl dye with γ-cyclodextrin: a drug-binding application using displacement assays.
    Physical chemistry chemical physics : PCCP, 2015, Jun-28, Volume: 17, Issue:24

    Topics: Acetaminophen; Ampicillin; Aspirin; beta-Cyclodextrins; Binding Sites; Chloramphenicol; Drug Delivery Systems; Fluorescence; Fluorescent Dyes; Fluorometry; Hydrogen-Ion Concentration; Ibuprofen; Kanamycin; Oxazines; Oxazoles; Piroxicam; Salicylates; Salicylic Acid; Sorbic Acid; Sulfonamides; Thiamphenicol; Xanthenes

2015
Aspirin delays mesothelioma growth by inhibiting HMGB1-mediated tumor progression.
    Cell death & disease, 2015, Jun-11, Volume: 6

    Topics: 3T3 Cells; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclooxygenase 2; Epithelial-Mesenchymal Transition; Female; HMGB1 Protein; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Mice; Mice, Knockout; Mice, SCID; Neoplasm Invasiveness; Salicylic Acid; Xenograft Model Antitumor Assays

2015
Aspirin's Active Metabolite Salicylic Acid Targets High Mobility Group Box 1 to Modulate Inflammatory Responses.
    Molecular medicine (Cambridge, Mass.), 2015, Jun-18, Volume: 21

    Topics: Aspirin; Cyclooxygenase 2; HMGB1 Protein; Humans; Inflammation; Mutation; Nuclear Magnetic Resonance, Biomolecular; Salicylic Acid

2015
Assessment of in vitro antiovulatory activities of nonsteroidal anti-inflammatory drugs and comparison with in vivo reproductive toxicities of medaka (Oryzias latipes).
    Environmental toxicology, 2016, Volume: 31, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diclofenac; Female; Humans; Ketoprofen; Mefenamic Acid; Oryzias; Ovary; Ovulation; Ovum; Reproduction; Salicylic Acid; Water Pollutants, Chemical

2016
Pharmacokinetic and pharmacodynamic interactions of aspirin with warfarin in beagle dogs.
    Xenobiotica; the fate of foreign compounds in biological systems, 2016, Volume: 46, Issue:6

    Topics: Animals; Aspirin; Dogs; Dose-Response Relationship, Drug; Drug Interactions; International Normalized Ratio; Male; Partial Thromboplastin Time; Platelet Aggregation Inhibitors; Prothrombin Time; Reference Standards; Salicylic Acid; Warfarin

2016
Human GAPDH Is a Target of Aspirin's Primary Metabolite Salicylic Acid and Its Derivatives.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Aspirin; Cell Death; Cell Line; Cell Nucleus; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Humans; Molecular Structure; Protein Binding; Protein Transport; Salicylic Acid

2015
A Novel Nitronyl Nitroxide with Salicylic Acid Framework Attenuates Pain Hypersensitivity and Ectopic Neuronal Discharges in Radicular Low Back Pain.
    Neural plasticity, 2015, Volume: 2015

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Aspirin; Behavior, Animal; Cyclic N-Oxides; Drug Synergism; Ganglia, Spinal; Hyperalgesia; Imidazoles; Low Back Pain; Male; Neurons; Radiculopathy; Rats; Rats, Sprague-Dawley; Salicylic Acid; Spin Labels; Spinal Cord Compression

2015
Cyclin A2 and CDK2 as Novel Targets of Aspirin and Salicylic Acid: A Potential Role in Cancer Prevention.
    Molecular cancer research : MCR, 2016, Volume: 14, Issue:3

    Topics: Aspirin; Cell Line, Tumor; Cell Proliferation; Cyclin A2; Cyclin-Dependent Kinase 2; Down-Regulation; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; MCF-7 Cells; Models, Molecular; Molecular Docking Simulation; Neoplasms; Protein Binding; Salicylic Acid

2016
Simultaneous determination of salicylic, 3-methyl salicylic, 4-methyl salicylic, acetylsalicylic and benzoic acids in fruit, vegetables and derived beverages by SPME-LC-UV/DAD.
    Journal of pharmaceutical and biomedical analysis, 2016, Mar-20, Volume: 121

    Topics: Aspirin; Benzoates; Benzoic Acid; Beverages; Chromatography, High Pressure Liquid; Dimethylpolysiloxanes; Fruit; Polyvinyls; Salicylic Acid; Solid Phase Microextraction; Ultraviolet Rays; Vegetables

2016
Newly Identified Targets of Aspirin and Its Primary Metabolite, Salicylic Acid.
    DNA and cell biology, 2016, Volume: 35, Issue:4

    Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Drug Repositioning; Glyceraldehyde-3-Phosphate Dehydrogenases; HMGB1 Protein; Humans; Salicylic Acid

2016
Preharvest salicylic acid and acetylsalicylic acid treatments preserve quality and enhance antioxidant systems during postharvest storage of sweet cherry cultivars.
    Journal of the science of food and agriculture, 2017, Volume: 97, Issue:4

    Topics: Agriculture; Anthocyanins; Antioxidants; Ascorbate Peroxidases; Ascorbic Acid; Aspirin; Catalase; Color; Food Handling; Food Preservation; Food Storage; Fruit; Hardness; Humans; Oxidation-Reduction; Peroxidase; Phenols; Prunus; Salicylic Acid; Superoxide Dismutase; Taste

2017
Simultaneous Determination of Aspirin, Dipyridamole and Two of Their Related Impurities in Capsules by Validated TLC-Densitometric and HPLC Methods.
    Journal of chromatographic science, 2016, Volume: 54, Issue:7

    Topics: Acetates; Aspirin; Capsules; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Densitometry; Dipyridamole; Hydrogen-Ion Concentration; Methanol; Reproducibility of Results; Salicylic Acid; Solvents; Tartrates; Toluene

2016
EPR studies of intermolecular interactions and competitive binding of drugs in a drug-BSA binding model.
    Physical chemistry chemical physics : PCCP, 2016, Aug-10, Volume: 18, Issue:32

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Binding Sites; Binding, Competitive; Electron Spin Resonance Spectroscopy; Ibuprofen; Pharmaceutical Preparations; Protein Binding; Salicylic Acid; Serum Albumin, Bovine; Spin Labels

2016
Aspirin for cancer is no mere antiplatelet prototype. There is potential in its ancient roots.
    Medical hypotheses, 2016, Volume: 94

    Topics: Animals; Aspirin; Blood Platelets; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Gastrointestinal Diseases; Humans; Neoplasms; Platelet Aggregation Inhibitors; Preventive Medicine; Risk; Salicylic Acid; Vascular Diseases

2016
Ethanol oxidation and the inhibition by drugs in human liver, stomach and small intestine: Quantitative assessment with numerical organ modeling of alcohol dehydrogenase isozymes.
    Chemico-biological interactions, 2016, Oct-25, Volume: 258

    Topics: Acetaminophen; Alcohol Dehydrogenase; Aspirin; Cimetidine; Ethanol; Gastric Mucosa; Genotype; Humans; Intestine, Small; Isoenzymes; Kinetics; Liver; Models, Biological; Oxidation-Reduction; Pharmaceutical Preparations; Salicylic Acid; Stomach; Substrate Specificity

2016
ABCC3 Polymorphisms and mRNA Expression Influence the Concentration of a Carboxylic Acid Metabolite in Patients on Clopidogrel and Aspirin Therapy.
    Basic & clinical pharmacology & toxicology, 2017, Volume: 120, Issue:5

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Carboxylic Acids; Chromatography, Liquid; Clopidogrel; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Genotype; Humans; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Polymorphism, Genetic; RNA, Messenger; Salicylic Acid; Tandem Mass Spectrometry; Ticlopidine; Up-Regulation

2017
Effect of Panax notoginseng saponins on the pharmacokinetics of aspirin in rats.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017, Jan-01, Volume: 1040

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cell Line; Chromatography, High Pressure Liquid; Dogs; Drug Interactions; Fibrinolytic Agents; Limit of Detection; Male; Panax notoginseng; Permeability; Rats; Rats, Sprague-Dawley; Salicylic Acid; Saponins; Tandem Mass Spectrometry

2017
Bioavailability of aspirin in rats comparing the drug's uptake into gastrointestinal tissue and vascular and lymphatic systems: implications on aspirin's chemopreventive action.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2016, Volume: 67, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Biological Availability; Drug Administration Routes; Intestinal Mucosa; Lymphatic System; Male; Rats; Rats, Sprague-Dawley; Salicylic Acid

2016
Quantitative determination of five metabolites of aspirin by UHPLC-MS/MS coupled with enzymatic reaction and its application to evaluate the effects of aspirin dosage on the metabolic profile.
    Journal of pharmaceutical and biomedical analysis, 2017, May-10, Volume: 138

    Topics: Animals; Aspirin; Chromatography, High Pressure Liquid; Glucuronates; Glucuronidase; Glucuronides; Hippurates; Male; Metabolome; Rats; Rats, Sprague-Dawley; Salicylates; Salicylic Acid; Tandem Mass Spectrometry

2017
How does the multifaceted plant hormone salicylic acid combat disease in plants and are similar mechanisms utilized in humans?
    BMC biology, 2017, 03-23, Volume: 15, Issue:1

    Topics: Agriculture; Aspirin; Cytosol; Disease Resistance; Humans; Plant Diseases; Plant Growth Regulators; Salicylic Acid; Signal Transduction

2017
Impaired liver cytochrome P450 2C11 activity after dual antiplatelet therapy with aspirin and clopidogrel in rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 2018, Volume: 48, Issue:9

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Aspirin; Chromatography, Liquid; Clopidogrel; Cytochrome P450 Family 2; Inactivation, Metabolic; Liver; Male; Platelet Aggregation Inhibitors; Rats, Sprague-Dawley; Salicylic Acid; Steroid 16-alpha-Hydroxylase; Tandem Mass Spectrometry; Ticlopidine

2018
Salicylic acid metabolites and derivatives inhibit CDK activity: Novel insights into aspirin's chemopreventive effects against colorectal cancer.
    International journal of oncology, 2017, Volume: 51, Issue:6

    Topics: Acetylation; Anticarcinogenic Agents; Aspirin; CDC2 Protein Kinase; Colorectal Neoplasms; Cyclin B1; HCT116 Cells; Humans; Hydroxybenzoates; Molecular Docking Simulation; Protein Kinase Inhibitors; Salicylic Acid

2017
Impact of Multidrug Resistance Protein-4 Inhibitors on Modulating Platelet Function and High on-Aspirin Treatment Platelet Reactivity.
    Thrombosis and haemostasis, 2018, Volume: 118, Issue:3

    Topics: Aged; Aspirin; Blood Platelets; Cilostazol; Cohort Studies; Cyclic AMP; Female; Humans; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prostaglandins H; Salicylic Acid; Thrombosis

2018
Effect of Red Ginseng Extract on the Pharmacokinetics of Aspirin Metabolite in Sprague Dawley Rats.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 2018, Jun-30, Volume: 33, Issue:2

    Topics: Animals; Aspirin; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Male; Panax; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Salicylic Acid

2018
Simultaneous determination of methocarbamol and aspirin in presence of their pharmacopeial-related substances in combined tablets using novel HPLC-DAD method.
    Drug development and industrial pharmacy, 2019, Volume: 45, Issue:2

    Topics: Acetic Acid; Acetonitriles; Aspirin; Calibration; Chromatography, High Pressure Liquid; Drug Combinations; Guaifenesin; Limit of Detection; Methocarbamol; Powders; Reference Standards; Reproducibility of Results; Salicylic Acid; Tablets

2019
Detection and monitoring of in vitro formation of salicylic acid from aspirin using fluorescence spectroscopic technique and DFT calculations.
    Journal of photochemistry and photobiology. B, Biology, 2018, Volume: 189

    Topics: Aspirin; Density Functional Theory; Humans; Hydrogen-Ion Concentration; Salicylic Acid; Spectrometry, Fluorescence

2018
Quantitative determination of carbasalate calcium derived metabolites, acetylsalicylic acid and salicylic acid, in six animal foods using liquid-liquid extraction method coupled with liquid chromatography-tandem mass spectrometry.
    Food chemistry, 2019, Apr-25, Volume: 278

    Topics: Acetonitriles; Animal Feed; Animals; Aspirin; Chromatography, Liquid; Food Analysis; Food Contamination; Limit of Detection; Liquid-Liquid Extraction; Milk; Red Meat; Salicylic Acid; Seafood; Swine; Tandem Mass Spectrometry; Urea

2019
Modulating Inflammation in Monocytes Using Capillary Fiber Organic Electronic Ion Pumps.
    Advanced healthcare materials, 2019, Volume: 8, Issue:19

    Topics: Aspirin; Cytokines; Drug Delivery Systems; Electrolytes; Electronics; Humans; Hydrogen-Ion Concentration; Inflammation; Interleukin-6; Ions; Lipopolysaccharides; Miniaturization; Monocytes; Organic Chemicals; Salicylic Acid; Tumor Necrosis Factor-alpha

2019
Role of aspirin-triggered lipoxin A4, aspirin, and salicylic acid in the modulation of the oxidative and inflammatory responses induced by plasma from women with pre-eclampsia.
    American journal of reproductive immunology (New York, N.Y. : 1989), 2020, Volume: 83, Issue:2

    Topics: Acetylation; Adolescent; Adult; Aspirin; Cell Adhesion; Cyclooxygenase 2; Female; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Lipoxins; Neutrophils; NF-kappa B; Oxidative Stress; Pre-Eclampsia; Pregnancy; Protein Processing, Post-Translational; Salicylic Acid; Thiobarbituric Acid Reactive Substances; Tyrosine; U937 Cells; Young Adult

2020
Salicylic acid and aspirin stimulate growth of Chlamydomonas and inhibit lipoxygenase and chloroplast desaturase pathways.
    Plant physiology and biochemistry : PPB, 2020, Volume: 149

    Topics: Aspirin; Chlamydomonas; Chloroplasts; Enzyme Activation; Enzyme Inhibitors; Fatty Acid Desaturases; Lipoxygenase; Salicylic Acid

2020
Translation of Microbiota Short-Chain Fatty Acid Mechanisms Affords Anti-infective Acyl-Salicylic Acid Derivatives.
    ACS chemical biology, 2020, 05-15, Volume: 15, Issue:5

    Topics: Acylation; Anti-Infective Agents; Aspirin; Clostridioides difficile; Drug Therapy, Combination; Esters; Fatty Acids, Volatile; Humans; Microbiota; Salicylic Acid; Salmonella typhimurium; Structure-Activity Relationship

2020
Low levels of salicylic acid and salicyluric acid are present in synovial fluid of patients taking aspirin at the time of knee arthroplasty surgery.
    Clinical and experimental pharmacology & physiology, 2020, Volume: 47, Issue:9

    Topics: Administration, Oral; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee; Aspirin; Drug Administration Schedule; Drug Monitoring; Female; Hippurates; Humans; Knee Prosthesis; Male; Prosthesis-Related Infections; Salicylic Acid; Synovial Fluid

2020
An interim internal Threshold of Toxicologic Concern (iTTC) for chemicals in consumer products, with support from an automated assessment of ToxCast™ dose response data.
    Regulatory toxicology and pharmacology : RTP, 2020, Volume: 114

    Topics: Acetic Acid; Animals; Aspirin; Automation; Dose-Response Relationship, Drug; Humans; Molecular Structure; No-Observed-Adverse-Effect Level; Receptors, Androgen; Risk Assessment; Salicylic Acid; Structure-Activity Relationship

2020
Preharvest application of methyl salicylate, acetyl salicylic acid and salicylic acid alleviated disease caused by Botrytis cinerea through stimulation of antioxidant system in table grapes.
    International journal of food microbiology, 2020, Dec-02, Volume: 334

    Topics: Antioxidants; Aspirin; Botrytis; Disease Resistance; Food Preservation; Phenols; Plant Diseases; Salicylates; Salicylic Acid; Vitis

2020
Green analysis of newly approved binary omeprazole/aspirin mixture in presence of aspirin impurity using ultra-high-performance liquid chromatography and thin-layer chromatography methods.
    Biomedical chromatography : BMC, 2021, Volume: 35, Issue:2

    Topics: Aspirin; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Drug Contamination; Green Chemistry Technology; Limit of Detection; Linear Models; Omeprazole; Reproducibility of Results; Salicylic Acid

2021
Acetylsalicylic acid and salicylic acid present anticancer properties against melanoma by promoting nitric oxide-dependent endoplasmic reticulum stress and apoptosis.
    Scientific reports, 2020, 11-12, Volume: 10, Issue:1

    Topics: AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Apoptosis; Aspirin; Cell Line, Tumor; Disease Models, Animal; Endoplasmic Reticulum Stress; Male; Melanoma; Mice, Inbred C57BL; Molecular Targeted Therapy; Nitric Oxide; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Salicylic Acid; Skin Neoplasms; TOR Serine-Threonine Kinases; Up-Regulation

2020
Spectrophotometric Determination of Aspirin and Omeprazole in the Presence of Salicylic Acid as a Degradation Product: A Comparative Evaluation of Different Univariate/Multivariate Post Processing Algorithms.
    Journal of AOAC International, 2022, Feb-04, Volume: 105, Issue:1

    Topics: Algorithms; Aspirin; Calibration; Humans; Least-Squares Analysis; Omeprazole; Salicylic Acid; Spectrophotometry

2022
Salicylic Acid and Risk of Colorectal Cancer: A Two-Sample Mendelian Randomization Study.
    Nutrients, 2021, 11-21, Volume: 13, Issue:11

    Topics: Aspirin; Case-Control Studies; Colorectal Neoplasms; Diet; Female; Genome-Wide Association Study; Genotyping Techniques; Humans; Male; Mendelian Randomization Analysis; Polymorphism, Single Nucleotide; Risk Factors; Salicylic Acid

2021
Micelle-Incorporated Liquid Chromatography in the Light of Green Chemistry: An Application for the Quality Control Analysis of Anti-Platelet Fixed-Dose Combinations.
    Journal of AOAC International, 2022, Sep-06, Volume: 105, Issue:5

    Topics: Aspirin; Chromatography, High Pressure Liquid; Chromatography, Liquid; Clopidogrel; Micelles; Quality Control; Reproducibility of Results; Salicylic Acid

2022
Monitoring of salicylic acid content in human saliva and its relationship with plasma concentrations.
    Journal of pharmaceutical and biomedical analysis, 2022, Sep-20, Volume: 219

    Topics: Aspirin; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Salicylic Acid; Saliva

2022
Salicylic acid directly binds to ribosomal protein S3 and suppresses CDK4 expression in colorectal cancer cells.
    Biochemical and biophysical research communications, 2022, 11-05, Volume: 628

    Topics: Aspirin; Colorectal Neoplasms; Cyclin-Dependent Kinase 4; Humans; Prospective Studies; Ribosomal Proteins; RNA, Small Interfering; Salicylic Acid; Sodium Salicylate

2022
Determination of milk concentrations and pharmacokinetics of salicylic acid following acetylsalicylic acid (aspirin) administration in postpartum dairy cows.
    Journal of dairy science, 2022, Volume: 105, Issue:12

    Topics: Animals; Aspirin; Cattle; Female; Lactation; Milk; Postpartum Period; Prostaglandins; Salicylic Acid

2022
A photoelectron spectroscopic investigation of aspirin, paracetamol and ibuprofen in the gas phase.
    Physical chemistry chemical physics : PCCP, 2023, Apr-12, Volume: 25, Issue:15

    Topics: Acetaminophen; Aspirin; Gases; Ibuprofen; Photoelectron Spectroscopy; Salicylic Acid

2023
Low dose acetyl salicylic acid (LDA) mediates epigenetic changes in preeclampsia placental mesenchymal stem cells similar to cells from healthy pregnancy.
    Placenta, 2023, Volume: 137

    Topics: Aspirin; Epigenesis, Genetic; Female; Humans; Mesenchymal Stem Cells; Placenta; Pre-Eclampsia; Pregnancy; Salicylic Acid

2023
A pharmacokinetics interaction study of antiplatelet agents aspirin and clopidogrel combined with dl-3-n-butylphthalide in rats by liquid chromatography-tandem mass spectrometry.
    Biomedical chromatography : BMC, 2023, Volume: 37, Issue:9

    Topics: Animals; Aspirin; Chromatography, High Pressure Liquid; Chromatography, Liquid; Clopidogrel; Platelet Aggregation Inhibitors; Rats; Salicylic Acid; Tandem Mass Spectrometry

2023
The Plasma Concentration of Ticagrelor and Aspirin as a Predictor of Bleeding Complications in Chinese Acute Coronary Syndrome Patients With Dual Antiplatelet Therapy: A Prospective Observational Study.
    Journal of cardiovascular pharmacology, 2023, 08-01, Volume: 82, Issue:2

    Topics: Acute Coronary Syndrome; Aspirin; East Asian People; Hemorrhage; Humans; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Salicylic Acid; ST Elevation Myocardial Infarction; Ticagrelor; Treatment Outcome

2023
Voltammetric quantification of acetylsalicylic acid in pharmaceutical formulations utilizing copper wire electrode.
    Pakistan journal of pharmaceutical sciences, 2023, Volume: 36, Issue:4

    Topics: Aspirin; Copper; Drug Compounding; Electrodes; Pharmaceutical Preparations; Salicylic Acid

2023
Association between 23 drugs and Parkinson's disease: A two-sample Mendelian randomization study.
    Brain and behavior, 2023, Volume: 13, Issue:11

    Topics: Aspirin; Fibrinolytic Agents; Genome-Wide Association Study; Humans; Mendelian Randomization Analysis; Parkinson Disease; Reproducibility of Results; Salicylic Acid

2023
A classification of headache.
    International ophthalmology clinics, 1970,Fall, Volume: 10, Issue:3

    Topics: Antidepressive Agents; Anxiety; Arteritis; Aspirin; Depression; Ergot Alkaloids; Facial Neuralgia; Headache; Histamine Release; Humans; Inflammation; Methysergide; Microcirculation; Migraine Disorders; Muscle Contraction; Myositis; Neck; Neuralgia; Osteoarthritis; Scalp; Serotonin Antagonists; Vascular Headaches; Vasoconstrictor Agents

1970
Craniofacial pain followed by scalp necrosis and stroke. An unusual presentation of the primary antiphospholipid syndrome.
    Journal of neurology, 1999, Volume: 246, Issue:2

    Topics: Aged; Antibodies, Antiphospholipid; Anticoagulants; Antiphospholipid Syndrome; Aspirin; Autoimmune Diseases; Blood Sedimentation; Brain Ischemia; Diagnosis, Differential; Facial Pain; Giant Cell Arteritis; Headache; Humans; Magnetic Resonance Imaging; Male; Necrosis; Scalp; Thrombophilia

1999
Subgaleal hematoma in a child with Sturge-Weber syndrome: to prevent stroke-like episodes, is treatment with aspirin advisable?
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2008, Volume: 24, Issue:12

    Topics: Aspirin; Child, Preschool; Craniocerebral Trauma; Hematoma; Humans; Male; Platelet Aggregation Inhibitors; Scalp; Stroke; Sturge-Weber Syndrome; Tomography Scanners, X-Ray Computed

2008
Brooke-Spiegler syndrome: report of a case of multiple cylindromas and trichoepitheliomas.
    Dermatology online journal, 2008, Jul-15, Volume: 14, Issue:7

    Topics: Administration, Topical; Aspirin; Biomarkers, Tumor; Biopsy, Needle; Carcinoma, Adenoid Cystic; Carcinoma, Skin Appendage; Combined Modality Therapy; Deubiquitinating Enzyme CYLD; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Lip; Male; Middle Aged; Mohs Surgery; Neoplasm Staging; Neoplastic Syndromes, Hereditary; Risk Assessment; Scalp; Skin Neoplasms; Treatment Outcome; Tumor Suppressor Proteins

2008