salicylates has been researched along with malic-acid* in 2 studies
2 other study(ies) available for salicylates and malic-acid
| Article | Year |
|---|---|
A bienzyme electrode for L-malate based on a novel and general design.
The coimmobilization of a NAD(P) + -dependent dehydrogenase with salicylate hydroxylase (SHL, EC 1.14.13.1) in front of a Clark-electrode yields a flexible new design for dehydrogenase based biosensors. The feasibility of the approach has been tested with malic enzyme (MDH, EC 1.1.1.40) as the dehydrogenase, resulting in a novel L-malate sensor. It had substantial advantages over the biosensor approaches reported earlier: effective re-oxidation of NADPH by SHL yielded an extended linear range from 0.01 to 1.2 mmol 1(-1) L-malate and strongly reduced NADP+ -requirement (<0.025 mmol 1(-1)), while the working stability was increased to more than 30 days. The results obtained from six real samples showed a close correlation with the standard enzymatic method. The presented scheme with SHL and the Clark-electrode can be employed together with any NAD(P)+ -dependent dehydrogenase. Topics: Biosensing Techniques; Biotechnology; Evaluation Studies as Topic; Food Analysis; Malate Dehydrogenase; Malates; Mixed Function Oxygenases; NADP; Salicylates; Salicylic Acid | 1998 |
Salicylic acid stimulation of palmitic acid oxidation by rat skeletal muscle mitochondria.
The effects of salicylic acid on palmitic acid oxidation were studied using rat skeletal muscle mitochondria. Salicylic acid, in concentrations that exerted no effect on mitochondrial coupling (0.1 mM), significantly stimulated mitochondrial palmitic acid oxidation, with maximal stimulation occurring at subsaturating concentrations of substrate. In the same preparation, salicylate had no effect on the oxidation of palmitoylcarnitine or palmitoyl-CoA. Salicylate appears to augment the initial step of palmitic acid oxidation by lowering the apparent Michaelis constant (Km) of long chain fatty acid: CoASH ligase (AMP) (EC 6.2.1.3) for palmitic acid. Topics: Animals; Coenzyme A Ligases; Malates; Male; Mitochondria, Muscle; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Palmitoyl Coenzyme A; Palmitoylcarnitine; Pyruvates; Pyruvic Acid; Rats; Repressor Proteins; Saccharomyces cerevisiae Proteins; Salicylates; Salicylic Acid | 1981 |