salicylates and gluconic-acid

salicylates has been researched along with gluconic-acid* in 1 studies

Other Studies

1 other study(ies) available for salicylates and gluconic-acid

ArticleYear
Response of Staphylococcus aureus to salicylate challenge.
    Journal of bacteriology, 2007, Volume: 189, Issue:1

    Growth of Staphylococcus aureus with the nonsteroidal anti-inflammatory salicylate reduces susceptibility of the organism to multiple antimicrobials. Transcriptome analysis revealed that growth of S. aureus with salicylate leads to the induction of genes involved with gluconate and formate metabolism and represses genes required for gluconeogenesis and glycolysis. In addition, salicylate induction upregulates two antibiotic target genes and downregulates a multidrug efflux pump gene repressor (mgrA) and sarR, which represses a gene (sarA) important for intrinsic antimicrobial resistance. We hypothesize that these salicylate-induced alterations jointly represent a unique mechanism that allows S. aureus to resist antimicrobial stress and toxicity.

    Topics: Anti-Infective Agents; Bacterial Proteins; Drug Resistance, Multiple, Bacterial; Formates; Gene Expression Regulation, Bacterial; Gluconates; Gluconeogenesis; Glycolysis; Microarray Analysis; RNA, Bacterial; RNA, Messenger; Salicylates; Staphylococcus aureus

2007