salicylates has been researched along with ethyl-cellulose* in 2 studies
2 other study(ies) available for salicylates and ethyl-cellulose
| Article | Year |
|---|---|
In vitro release of salicylic acid from lanolin alcohols-ethylcellulose films.
Lanolin alcohols-ethylcellulose films were investigated as a potential drug delivery system for the controlled release of salicylic acid. The effects of changes in film composition, drug concentration, drug solubility, and stirrer speed on the in vitro release of salicylic acid have been examined. The drug release has been found to obey a diffusion-controlled matrix model and square root of time release profile both in the suspension and solution cases. Topics: Alcohols; Cellulose; Chemistry, Pharmaceutical; Lanolin; Plasticizers; Propylene Glycol; Propylene Glycols; Salicylates; Salicylic Acid; Solubility; Solvents | 1984 |
Influence of drug partition coefficient and pH value of sink solution on permeation from porous thick-walled ethyl cellulose microcapsules.
The permeation of barbitone sodium, benzoic acid, and salicylic acid from microcapsules into aqueous medium has been examined at different pH values. The apparent diffusion coefficients of drugs were linearly proportional to the ethyl cellulose/water partition coefficient of drugs, and the straight line parameters were dependent upon volume fractions of water-filled pores (i.e. capsule size), testifying to a previously proposed mechanism of drug permeation. The rate of drug permeation was also a function of the pH-value of the surrounding sink solution; the period of zero order release was longer at low pH because of the change of drug partition or solubility or both. Topics: Barbital; Benzoates; Benzoic Acid; Capsules; Cellulose; Diffusion; Half-Life; Hydrogen-Ion Concentration; Permeability; Pharmaceutical Preparations; Salicylates; Salicylic Acid; Solubility | 1983 |