salicylates and azobenzene

Controlling physicochemical properties of light-unresponsive drugs, by light, prima facie, a paradox approach. We expanded light control by ion pairing light-unresponsive salicylate or ibuprofen to photoswitchable azobenzene counterions, thereby reversibly controlling supramolecular structures, hence the drugs' physicochemical and kinetic properties. The resulting ion pairs photoliquefied into room-temperature ionic liquids under ultraviolet light. Aqueous solutions showed

Topics: Azo Compounds; Chemistry, Pharmaceutical; Ibuprofen; Ionic Liquids; Molecular Structure; Permeability; Salicylates; Ultraviolet Rays; Water