salicylates has been researched along with 4-phenylbenzoic-acid* in 2 studies
2 other study(ies) available for salicylates and 4-phenylbenzoic-acid
Article | Year |
---|---|
Biologic testing of leachable aromatic compounds from denture base materials.
The aromatic compounds phenyl benzoate (PB), phenyl salicylate (PS), and biphenyl (BP), which have previously been found to leach from poly(methyl methacrylate) denture base materials, were tested for cytotoxicity and biologic effects by L929 cells in culture. The octanol-water partition coefficient (log P(ow), a descriptor for the lipophilicity, was determined for the compounds. Cytotoxicity was evaluated by total cell growth and the plating efficiency test, and biologic effects by the total fatty acid composition of L929 cells. The commonly used tests, total cell growth and plating efficiency, did not show any significant changes of the cells due to the compounds. On the other hand, BP and PS, in particular, induced changes in the total fatty acid composition of L929 cells. The problem of bioavailability of aromatic compounds in cell culture assays and the relation to lipophilicity was addressed. Topics: Animals; Biocompatible Materials; Biological Availability; Biphenyl Compounds; Cell Division; Cells, Cultured; Denture Bases; Fatty Acids; Fibroblasts; Lipids; Materials Testing; Methylmethacrylates; Mice; Salicylates | 1995 |
Leaching of additives and degradation products from cold-cured orthodontic resins.
Unstimulated saliva was collected from orthodontic patients and subjected to combined gas-chromatography and gas-chromatography/mass-spectrometry analyses. Saliva was collected before insertion of removable orthodontic appliances made of cold-cured resins. Saliva was then collected 1-2 months after insertion of the appliances and 1 week after they had been removed. Phenyl benzoate (PB) and phenyl salicylate (PS) were identified in pooled saliva samples from patients wearing the appliances. Biphenyl and 2-methoxy-4-hydroxy-benzophenone in addition to PB and PS were identified in a study with in vitro specimens made of orthodontic resin. The leaching of compounds from these test specimens processed by a powdering technique and a pre-mix technique was compared. Topics: Biphenyl Compounds; Child; Chromatography, Gas; Chromatography, High Pressure Liquid; Diffusion; Ethanol; Female; Gas Chromatography-Mass Spectrometry; Humans; Isotonic Solutions; Male; Microscopy, Electron, Scanning; Orthodontic Appliances; Resins, Synthetic; Ringer's Solution; Salicylates; Saliva; Surface Properties; Time Factors | 1994 |