Page last updated: 2024-09-03

saintopin and camptothecin

saintopin has been researched along with camptothecin in 3 studies

Compound Research Comparison

Studies
(saintopin)
Trials
(saintopin)
Recent Studies (post-2010)
(saintopin)
Studies
(camptothecin)
Trials
(camptothecin)
Recent Studies (post-2010) (camptothecin)
70013,0022,2295,391

Protein Interaction Comparison

ProteinTaxonomysaintopin (IC50)camptothecin (IC50)
Histone deacetylase 3Homo sapiens (human)0.05
Multidrug resistance-associated protein 4Homo sapiens (human)7.4
DNA topoisomerase 1Homo sapiens (human)1.9799
Somatostatin receptor type 1Homo sapiens (human)0.0022
Somatostatin receptor type 2Homo sapiens (human)0.0022
Somatostatin receptor type 4Homo sapiens (human)0.0022
Somatostatin receptor type 3Homo sapiens (human)0.0022
Somatostatin receptor type 5Homo sapiens (human)0.0022
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.97
Histone deacetylase 4Homo sapiens (human)0.05
Histone deacetylase 1Homo sapiens (human)0.05
Histone deacetylase 7Homo sapiens (human)0.05
Histone deacetylase 2Homo sapiens (human)0.05
Polyamine deacetylase HDAC10Homo sapiens (human)0.05
Histone deacetylase 11 Homo sapiens (human)0.05
Histone deacetylase 8Homo sapiens (human)0.05
Histone deacetylase 6Homo sapiens (human)0.05
Histone deacetylase 9Homo sapiens (human)0.05
Histone deacetylase 5Homo sapiens (human)0.05

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fujii, N; Kawada, S; Nakano, H; Yamashita, Y1
Kanematsu, T; Kawanami, K; Kohno, K; Kuwano, M; Taniguchi, K; Wada, M1
Futamata, K; Futamata, M; Ishiyama, D; Kamo, S; Kanazawa, S; Kasuya, O; Yamashita, F1

Other Studies

3 other study(ies) available for saintopin and camptothecin

ArticleYear
Induction of mammalian DNA topoisomerase I and II mediated DNA cleavage by saintopin, a new antitumor agent from fungus.
    Biochemistry, 1991, Jun-18, Volume: 30, Issue:24

    Topics: Amsacrine; Animals; Antibiotics, Antineoplastic; Benz(a)Anthracenes; Camptothecin; Cattle; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Bacterial; Doxorubicin; Escherichia coli; Kinetics; Plasmids; Thymus Gland

1991
Drug-induced down-regulation of topoisomerase I in human epidermoid cancer cells resistant to saintopin and camptothecins.
    Cancer research, 1996, May-15, Volume: 56, Issue:10

    Topics: Antibiotics, Antineoplastic; Benz(a)Anthracenes; Camptothecin; Carcinoma, Squamous Cell; Dactinomycin; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Enzyme Induction; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; KB Cells; Neoplasm Proteins; RNA, Messenger; RNA, Neoplasm; Topoisomerase I Inhibitors; Tumor Cells, Cultured

1996
Novel selective inhibitors for human topoisomerase I, BM2419-1 and -2 derived from saintopin.
    The Journal of antibiotics, 1998, Volume: 51, Issue:12

    Topics: Animals; Anthracyclines; Antibiotics, Antineoplastic; Benz(a)Anthracenes; Camptothecin; Chemical Phenomena; Chemistry, Physical; DNA Topoisomerases, Type I; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Molecular Structure; Paecilomyces; Recombinant Proteins; Saccharomyces cerevisiae; Topoisomerase I Inhibitors; Tumor Cells, Cultured

1998