saikosaponin d has been researched along with sapogenins in 97 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (39.18) | 18.7374 |
| 1990's | 47 (48.45) | 18.2507 |
| 2000's | 11 (11.34) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (1.03) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, FK; Guo, YZ; Kano, Y; Meng, XS | 1 |
| Du, X; Liu, M | 1 |
| Abe, H; Ushio, Y | 4 |
| Abe, H; Oda, Y; Ushio, Y | 1 |
| Chuang, CH; Lin, CC; Liu, SY; Yen, MH | 1 |
| Du, X; Jiang, C; Liu, M | 1 |
| Chang, WC; Hsu, FL | 1 |
| Hattori, T; Ito, M; Suzuki, Y | 1 |
| Hayashi, T; Horii, I; Nakayama, Y; Nishiyama, T; Ozawa, T | 1 |
| Kawakita, T; Kumazawa, Y; Nomoto, K; Takimoto, H | 1 |
| Kanazawa, H; Matsushima, Y; Nagata, Y; Takai, N; Tomoda, M | 1 |
| Amagaya, S; Nose, M; Ogihara, Y | 2 |
| Dong, YY; Luo, SQ | 1 |
| Jia, Q; Zhang, RY | 1 |
| Kawakita, T; Kumazawa, Y; Nishimura, C; Nomoto, K; Takimoto, H | 1 |
| Abe, H; Arichi, S; Konishi, H; Odashima, S; Orita, M | 2 |
| Arichi, S; Hashimoto, M; Inada, K; Kimura, Y; Ohminami, H; Okuda, H | 1 |
| Zhang, J | 1 |
| Zhang, WX | 1 |
| Jyumonji, N; Kohno, H; Odashima, S; Yamaguchi, N; Yamazaki, M | 1 |
| Jin, RL; Kuang, Y; Shi, L | 1 |
| Hiai, S; Yokoyama, H | 2 |
| Amagaya, S; Iwama, H; Ogihara, Y | 1 |
| Motomura, H; Sakuma, S | 1 |
| Fujiwara, K; Ogihara, Y | 1 |
| Abe, H; Kohno, H; Odashima, S; Tawara, M; Yamaguchi, N | 1 |
| Ohuchi, K; Ozeki, T; Tsurufuji, S; Watanabe, M | 1 |
| Ito, K; Kimata, H; Matsufuji, N; Morita, T; Sumida, N; Tanaka, O; Yata, N | 1 |
| Amagaya, S; Ogihara, Y; Shimizu, K | 2 |
| Liu, AJ; Wang, BZ; Wang, GZ | 1 |
| Li, XZ | 1 |
| Chang, XL | 1 |
| Ma, JL; Wang, GZ; Zhou, ZC | 1 |
| Arichi, S; Hayashi, T; Kimura, Y; Ohminami, H; Okuda, H; Tani, T | 1 |
| Hiraoka, E; Hirotani, Y; Kishi, H; Maeda, Y; Oishi, M; Yamaji, A; Yoneda, K | 1 |
| Han, DW; Li, CM; Ma, XH; Yin, L; Zhao, MQ; Zhao, YC | 1 |
| Hiai, S; Oura, H; Yokoyama, H | 2 |
| Abe, H; Arichi, S; Odashima, S; Sakaguchi, M | 1 |
| Abe, H; Arichi, S; Sakaguchi, M | 1 |
| Abe, H; Arichi, S; Odashima, S; Sakaguchi, M; Yamada, M | 1 |
| Abe, H; Anno, M; Arichi, S; Sakaguchi, M | 1 |
| Hiai, S; Nagasawa, T; Oura, H; Yokoyama, H | 1 |
| Abe, H; Arichi, S; Komiya, H; Konishi, H | 1 |
| Hata, T; Itoh, E; Kita, T; Yoneda, R | 1 |
| Lin, CC; Liu, SY; Son, LM; Wang, JY; Wu, WK; Yen, MH | 1 |
| Hattori, T; Isobe, K; Kato, M; Nakashima, I; Pu, MY; Yanagita, N | 1 |
| Li, Q; Murakamio, T; Okita, K; Takahashi, M | 1 |
| Giner, RM; Hostettmann, K; Just, MJ; Mañez, S; Recio, MC; Rios, JL | 1 |
| Kimura, Y; Murakami, T; Okita, K; Qian, L; Takahashi, M | 1 |
| Hattori, T; Isobe, K; Iwamoto, T; Kato, M; Lwin, T; Nagase, F; Nakashima, I; Pu, MY; Yanagita, N; Zhang, YH | 1 |
| Chang, TY; Hung, CR; Wu, TS | 1 |
| Chen, XK; Jiang, TY; Wang, B; Zhang, RY; Zhang, ZL | 1 |
| Maeda, T; Miyase, T; Ueno, A; Yamamoto, A | 1 |
| Ishihara, K; Ito, K; Kosuge, E; Kuriyama, M; Nakamura, T | 1 |
| Ashida, K; Hasegawa, C; Minami, M; Ohe, C; Sugino, M; Yomo, T | 1 |
| Dobashi, I; Horiba, N; Sakai, K; Sakai, Y; Suda, T; Tozawa, F | 1 |
| Fujikawa-Yamamoto, K; Odashima, S; Tanino, M; Teraoka, K; Yamagishi, H; Zong, Z | 1 |
| Fukuda, K; Kojiro, M; Ohtsuka, M; Yano, H | 1 |
| Kawachi, H; Li, P; Morioka, T; Oite, T; Orikasa, M; Shi, ZS; Shimizu, F | 1 |
| Matsushima, Y; Miyase, T | 1 |
| Horikoshi, C; Kusano, G; Melek, FR; Miyasaka, S; Miyase, T; Yabe, S | 1 |
| Akao, T; Hattori, M; Kida, H; Meselhy, MR | 2 |
| Kashimoto, T; Kudo, K; Tachikawa, E; Takahashi, E | 1 |
| Ebizuka, Y; Jung, DW; Shibuya, M; Shimomura, K; Sung, CK; Yoshimatsu, K | 1 |
| Abad Martínez, MJ; Bermejo Benito, P; Díaz Lanza, AM; Fernández Matellano, L; Sánchez Contreras, S; Sanz Gómez, A; Silván Sen, AM | 1 |
| Hiai, S; Nagasawa, T; Zhang, ZQ; Zhou, QL | 1 |
| Jiang, Y; Jing, H; Luo, S | 1 |
| Fujikawa-Yamamoto, K; Guan, X; Li, A; Murakami, M; Odashima, S; Ota, T; Tanino, M; Yamaguchi, N; Zong, Z | 1 |
| Jung, DW; Sung, CK | 1 |
| Cai, S; Tan, L; Tu, G; Wang, B; Zhang, R; Zhao, Y | 1 |
| Kodama, Y; Kubo, M; Kyo, R; Nakahata, N; Nakai, Y; Ohizumi, Y | 1 |
| Kang, EM; Kim, N; Park, IS | 1 |
| Cheng, JS; Hsu, MJ; Huang, HC | 1 |
| Liang, H; Liu, QX; Wang, B; Yang, WX; Yu, Y; Zhao, YY | 1 |
| Hsu, HY; Wu, WS | 1 |
| Cui, R; Liang, Y | 1 |
| Kim, N; Park, IS | 1 |
| Nomura, T; Wang, Y; Xing, S; Yano, Y | 1 |
| Bu, S; Sun, J; Xu, J | 2 |
| Aoyagi, H; Kobayashi, Y; Kusakari, K; Tanaka, H; Yamada, K; Yokoyama, M | 1 |
| Abad, MJ; Bermejo, P; Carrasco, L; De Santos, J; Díaz, AM; Fernández, L; Irurzun, A; Sanchez, S; Villaescusa, L | 1 |
| Chen, IL; Horng, LY; Tsai, YJ; Wu, RT | 1 |
| Huang, J; Liang, H; Qiu, H; Zhang, R; Zhao, Y | 1 |
| Bai, Y; Liang, H; Tu, G; Zhang, R; Zhao, Y | 1 |
| Dong, ZY; Liu, BH; Wang, H; Yang, WX; Yu, Y; Zhang, WZ | 1 |
| Koh, D; Lim, Y; Park, J; Park, KH | 1 |
| Im, WT; Kim, JH; Lee, JE; Siddiqi, MZ; Song, BK | 1 |
97 other study(ies) available for saikosaponin d and sapogenins
| Article | Year |
|---|---|
[The identification and determination of marker substances in xiaoyao wan by three dimensional HPLC].
Topics: Benzoates; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Glucosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Monoterpenes; Oleanolic Acid; Sapogenins; Saponins | 1992 |
[A histochemical study of saikosaponins].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drugs, Chinese Herbal; Histocytochemistry; Immunosuppressive Agents; Oleanolic Acid; Sapogenins; Saponins | 1992 |
Inactivation of measles virus and herpes simplex virus by saikosaponin d.
Topics: Animals; Antiviral Agents; Carbohydrate Sequence; Cell Division; Measles virus; Molecular Sequence Data; Oleanolic Acid; Sapogenins; Saponins; Vero Cells; Virus Replication | 1992 |
Effects of saikosaponin-d on the functions and morphology of macrophages.
Topics: Animals; Cell Movement; Cytoskeleton; Injections, Intramuscular; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Microscopy, Phase-Contrast; Morphogenesis; Oleanolic Acid; Peritoneal Lavage; Phagocytosis; Sapogenins; Saponins | 1991 |
Effect of saikosaponin on the immune responses in mice.
Topics: Animals; Cell Division; Hemolytic Plaque Technique; Immunity; Injections, Intramuscular; Interleukin-1; Lymphocyte Activation; Lysosomes; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred BALB C; Oleanolic Acid; Peritoneal Lavage; Phagocytosis; Sapogenins; Saponins; Spleen | 1991 |
Evaluation of root quality of Bupleurum species by TLC scanner and the liver protective effects of "xiao-chai-hu-tang" prepared using three different Bupleurum species.
Topics: Animals; Calibration; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chromatography, Thin Layer; Drugs, Chinese Herbal; Liver; Liver Diseases; Male; Oleanolic Acid; Plant Extracts; Rats; Rats, Inbred Strains; Sapogenins; Saponins | 1991 |
[Dynamic variation of saikosaponin contents].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Immunosuppressive Agents; Oleanolic Acid; Plants, Medicinal; Sapogenins; Saponins; Spectrophotometry, Ultraviolet; Time Factors | 1991 |
The effects of saikosaponin on macrophage functions and lymphocyte proliferation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Cells, Cultured; Chemotaxis, Leukocyte; Immunosuppressive Agents; Lymphocytes; Macrophages; Male; Mice; Mice, Inbred ICR; Oleanolic Acid; Phagocytosis; Plants; Sapogenins; Saponins | 1991 |
The effects of saikosaponin-d on yeast phagocytosis and degradation in peritoneal macrophages: related increase in Fc receptor expression and altered cytoplasmic organization.
Topics: Acid Phosphatase; Animals; Cytoplasm; Macrophages; Male; Mice; Mice, Inbred BALB C; Microscopy, Electron; Oleanolic Acid; Peritoneal Cavity; Phagocytosis; Receptors, Fc; Sapogenins; Saponins; Yeasts | 1991 |
Inhibition of platelet activation and endothelial cell injury by flavan-3-ol and saikosaponin compounds.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Cattle; Cells, Cultured; Endothelium, Vascular; Flavonoids; Humans; Hydrogen Peroxide; Oleanolic Acid; Platelet Aggregation; Platelet Aggregation Inhibitors; Sapogenins; Saponins; Thromboxane B2 | 1991 |
[Studies on antinephritic effects of plant components in rats (1). Effects of saikosaponins original-type anti-GBM nephritis in rats and its mechanisms].
Topics: Animals; Cholesterol; Corticosterone; Free Radical Scavengers; Glomerulonephritis; Glutathione Peroxidase; Kidney; Male; Oleanolic Acid; Platelet Aggregation; Platelet Aggregation Inhibitors; Proteinuria; Rats; Rats, Inbred Strains; Sapogenins; Saponins; Superoxide Dismutase | 1991 |
A distinct characteristic of the quiescent state of human dermal fibroblasts in contracted collagen gel as revealed by no response to epidermal growth factor alone, but a positive growth response to a combination of the growth factor and saikosaponin b1.
Topics: Adult; Cell Division; Cells, Cultured; Collagen; Contact Inhibition; Drug Synergism; Epidermal Growth Factor; ErbB Receptors; Female; Fibroblasts; Gels; Humans; Infant, Newborn; Male; Molecular Structure; Oleanolic Acid; Sapogenins; Saponins; Signal Transduction; Skin | 1990 |
Protective effect of saikosaponin A, saikosaponin D and saikogenin D against Pseudomonas aeruginosa infection in mice.
Topics: Animals; Injections, Intraperitoneal; Listeriosis; Mice; Oleanolic Acid; Pseudomonas Infections; Sapogenins; Saponins | 1990 |
Simultaneous determination of ginsenosides and saikosaponins by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Ginsenosides; Glycyrrhiza; Immunosuppressive Agents; Oleanolic Acid; Panax; Plants; Plants, Medicinal; Sapogenins; Saponins | 1990 |
Corticosterone secretion-inducing activity of saikosaponin metabolites formed in the alimentary tract.
Topics: Animals; Biotransformation; Corticosterone; Digestive System; Male; Mice; Oleanolic Acid; Sapogenins; Saponins; Stimulation, Chemical | 1989 |
[Determination of saikosaponins in radix Bupleuri using HPLC].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Oleanolic Acid; Sapogenins; Saponins; Species Specificity | 1989 |
Effects of saikosaponin metabolites on the hemolysis of red blood cells and their adsorbability on the cell membrane.
Topics: Adsorption; Erythrocyte Membrane; Hemolysis; Humans; In Vitro Techniques; Oleanolic Acid; Sapogenins; Saponins | 1989 |
[Advances in research on the chemistry of saponins in Bupleurum].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Chemistry; Immunosuppressive Agents; Molecular Conformation; Oleanolic Acid; Sapogenins; Saponins | 1989 |
Activation of murine peritoneal macrophages by saikosaponin a, saikosaponin d and saikogenin d.
Topics: Animals; Female; Histocompatibility Antigens Class II; Injections, Intraperitoneal; Lysosomes; Macrophage Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Molecular Structure; Oleanolic Acid; Sapogenins; Saponins | 1989 |
Effects of saikosaponin-d on enhanced CCl4-hepatotoxicity by phenobarbitone.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Carbon Tetrachloride Poisoning; Drug Synergism; Enzyme Induction; Lipid Peroxides; Liver; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oleanolic Acid; Phenobarbital; Rats; Rats, Inbred Strains; Sapogenins; Saponins; Time Factors | 1985 |
Effects of saikosaponins on liver tyrosine aminotransferase activity induced by cortisone in adrenalectomized rats.
Topics: Adrenalectomy; Animals; Cortisone; Enzyme Induction; Liver; Male; Oleanolic Acid; Rats; Rats, Inbred Strains; Sapogenins; Saponins; Tyrosine Transaminase | 1985 |
[Comparison on saikosaponin levels in the root of Bupleurum chinense of various sizes].
Topics: Medicine, Chinese Traditional; Medicine, East Asian Traditional; Oleanolic Acid; Plants, Medicinal; Sapogenins; Saponins; Time Factors | 1985 |
[Variation of saponins for Bupleurm scorzonerifolium and B. chinese in the extraction process and their effect on hemolysis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Hemolysis; Hot Temperature; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Oleanolic Acid; Plants, Medicinal; Sapogenins; Saponins | 1985 |
An investigation of the immune suppression induced by some saikosaponin derivatives.
Topics: Animals; Antibodies, Monoclonal; Antilymphocyte Serum; Drugs, Chinese Herbal; Female; Immunization, Passive; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Oleanolic Acid; Sapogenins; Saponins; Spleen; T-Lymphocytes, Regulatory | 1988 |
[Comparative studies on the roots of wild and cultured Bupleurum chinense DC].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drugs, Chinese Herbal; Oleanolic Acid; Plants, Medicinal; Sapogenins; Saponins | 1988 |
Effect of chronic treatment with saikosaponin d and dexamethasone on responsiveness of pituitary and adrenal cortex and adrenal weight in rats.
Topics: Adrenal Cortex; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Male; Oleanolic Acid; Organ Size; Pituitary Gland; Rats; Rats, Inbred Strains; Sapogenins; Saponins | 1987 |
Studies of the combined use of steroid and Shosaikoto, one of the Kampohozai (Chinese traditional medicine), on pituitary adrenocortical axis function and immune responses.
Topics: Adrenal Glands; Animals; Body Weight; Corticosterone; Drugs, Chinese Herbal; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hemagglutinins; Hemolytic Plaque Technique; Immunity; Male; Mice; Mice, Inbred ICR; Oleanolic Acid; Organ Size; Pituitary-Adrenal System; Plant Extracts; Plants, Medicinal; Prednisolone; Rats; Rats, Inbred Strains; Rosette Formation; Sapogenins; Saponins; Spleen | 1986 |
Purification of saikosaponins a, c and d. Application of large-scale reversed high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Japan; Oleanolic Acid; Plants, Medicinal; Sapogenins; Saponins | 1987 |
Chronic effect of saikosaponin on adrenal and thymus growth in normal and dexamethasone-treated rats.
Topics: Adrenal Glands; Animals; Body Weight; Dexamethasone; Male; Oleanolic Acid; Organ Size; Rats; Rats, Inbred Strains; Sapogenins; Saponins; Thymus Gland | 1986 |
Pharmacological effects of oral saikosaponin a may differ depending on conditions of the gastrointestinal tract.
Topics: Animals; Intestinal Absorption; Liver; Male; Oleanolic Acid; Protein Biosynthesis; Rats; Sapogenins; Saponins | 1986 |
Effect of saikosaponin derivatives upon the immune response against T-dependent and T-independent antigens in mice.
Topics: Animals; Antibody-Producing Cells; Antigens, T-Independent; Erythrocytes; Female; Hemolytic Plaque Technique; Immunity; Immunosuppressive Agents; Male; Mice; Mice, Inbred BALB C; Oleanolic Acid; Sapogenins; Saponins; Sheep; T-Lymphocytes | 1985 |
Pharmacological influence of saikosaponins on prostaglandin E2 production by peritoneal macrophages.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; In Vitro Techniques; Macrophages; Male; Mice; Muscle Contraction; Muscle, Smooth; Oleanolic Acid; Prostaglandins E; Rats; Rats, Inbred Strains; Sapogenins; Saponins | 1985 |
Effects of saikosaponin-d on aminonucleoside nephrosis in rats.
Topics: Animals; Blood Proteins; Cholesterol; Female; Kidney; Microscopy, Electron, Scanning; Nephrosis; Oleanolic Acid; Proteinuria; Puromycin; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Sapogenins; Saponins | 1986 |
Interaction of saponin of bupleuri radix with ginseng saponin: solubilization of saikosaponin-a with chikusetsusaponin V (= ginsenoside-Ro).
Topics: Animals; Chemical Phenomena; Chemistry; Ginsenosides; Hemolysis; In Vitro Techniques; Oleanolic Acid; Panax; Plants, Medicinal; Sapogenins; Saponins; Sheep | 1985 |
Structural transformation of saikosaponins by gastric juice and intestinal flora.
Topics: Animals; Bacteria; Biotransformation; Chromatography, High Pressure Liquid; Fasting; Feces; Gastric Acid; In Vitro Techniques; Intestines; Kinetics; Mice; Oleanolic Acid; Rats; Sapogenins; Saponins | 1985 |
[Anti-inflammatory effect of saikosaponins (author's transl)].
Topics: Animals; Anti-Inflammatory Agents; Cell Migration Inhibition; Edema; Granuloma; Histamine Release; Oleanolic Acid; Rats; Sapogenins; Saponins | 1981 |
[Research on the pharmacology of Bupleurum chinensis].
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Mice; Oleanolic Acid; Plants, Medicinal; Rats; Sapogenins; Saponins | 1983 |
[Comparison of the quality of cultivated and wild Bupleurum chinensis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Sapogenins; Saponins | 1983 |
The anti-allergic inflammation action of Saikosaponins.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthus Reaction; Female; Hypersensitivity; Hypersensitivity, Delayed; Male; Mice; Oleanolic Acid; Passive Cutaneous Anaphylaxis; Rats; Sapogenins; Saponins | 1983 |
Effects of saikosaponins on the metabolic actions of adrenaline, ACTH and insulin on the fat cells.
Topics: Adipose Tissue; Adrenocorticotropic Hormone; Animals; Epinephrine; In Vitro Techniques; Insulin; Male; Oleanolic Acid; Rats; Sapogenins; Saponins | 1980 |
[Determination of saikosaponins in Chinese medicinal extracts containing Bupleuri radix].
Topics: Anti-Inflammatory Agents; Chromatography, High Pressure Liquid; Medicine, Chinese Traditional; Medicine, East Asian Traditional; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Sapogenins; Saponins | 1984 |
[Preventive and therapeutic actions of glycyrrhizin, glycyrrhetic acid and crude saikosides on experimental liver cirrhosis in rats].
Topics: Animals; Collagen; Fatty Liver; Female; Glycyrrhetinic Acid; Glycyrrhizic Acid; Hepatitis; Liver Cirrhosis; Male; Oleanolic Acid; Rats; Sapogenins; Saponins | 1983 |
Quantitative analysis of the metabolites of saikosaponin a using high-performance liquid chromatography.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Chromatography, High Pressure Liquid; Male; Mice; Oleanolic Acid; Sapogenins; Saponins; Time Factors | 1984 |
Effect of saikosaponins on dexamethasone suppression of the pituitary-adrenocortical system.
Topics: Animals; Corticosterone; Dexamethasone; Male; Oleanolic Acid; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Sapogenins; Saponins | 1984 |
Protective effect of saikosaponin-d isolated from Bupleurum falcatum L. on CCl4-induced liver injury in the rat.
Topics: Animals; Body Weight; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Lipid Peroxides; Male; Microsomes, Liver; Necrosis; Oleanolic Acid; Organ Size; Plants, Medicinal; Rats; Rats, Inbred Strains; Sapogenins; Saponins | 1982 |
[Pharmacological studies on a prescription containing Bupleuri Radix (IV). Effects of saikosaponin on the anti-inflammatory action of glucocorticoid].
Topics: Animals; Body Weight; Dexamethasone; Drug Combinations; Drug Therapy, Combination; Granuloma; Injections, Intramuscular; Lipids; Male; Oleanolic Acid; Organ Size; Plants, Medicinal; Rats; Rats, Inbred Strains; Sapogenins; Saponins | 1982 |
Pharmacological actions of saikosaponins isolated from Bupleurum falcatum. 1. Effects of saikosaponins on liver function.
Topics: Animals; In Vitro Techniques; Liver; Male; Microsomes, Liver; Oleanolic Acid; Plants, Medicinal; Rats; Sapogenins; Saponins | 1980 |
Erythrocyte membrane stabilization by plant saponins and sapogenins.
Topics: Animals; Erythrocyte Membrane; Erythrocytes; Hemolysis; Hot Temperature; In Vitro Techniques; Male; Oleanolic Acid; Osmolar Concentration; Rats; Sapogenins; Saponins; Structure-Activity Relationship | 1981 |
Stimulation of the pituitary-adrenocortical axis by saikosaponin of Bupleuri radix.
Topics: Animals; Male; Oleanolic Acid; Pituitary-Adrenal System; Plants, Medicinal; Rats; Sapogenins; Saponins; Stimulation, Chemical | 1981 |
Chemical structures and corticosterone secretion-inducing activities of saikosaponins.
Topics: Animals; Chemical Phenomena; Chemistry; Corticosterone; Male; Oleanolic Acid; Rats; Sapogenins; Saponins; Stimulation, Chemical | 1981 |
Effects of saikosaponins on biological membranes. 3. Ultrastructural studies on effects of saikosaponins on the cell surface.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Membrane; Cells, Cultured; Mice; Oleanolic Acid; Sapogenins; Saponins; Surface Properties | 1981 |
Analgesic and other pharmacologic actions of saiko-saponin in repeated cold stressed (SART stressed) animals.
Topics: Acetylcholine; Analgesics; Animals; Behavior, Animal; Body Weight; Cold Temperature; Galvanic Skin Response; Male; Mice; Muscle Contraction; Oleanolic Acid; Rats; Sapogenins; Saponins; Sleep; Stress, Physiological | 1980 |
Studies on the agronomic characteristics, yield, and saikosaponin content of two Bupleurum species in Taiwan.
Topics: Bupleurum; Drugs, Chinese Herbal; Germination; Immunosuppressive Agents; Oleanolic Acid; Plant Extracts; Plant Roots; Sapogenins; Saponins; Seeds; Time Factors | 1995 |
Cell type-oriented differential modulatory actions of saikosaponin-d on growth responses and DNA fragmentation of lymphocytes triggered by receptor-mediated and receptor-bypassed pathways.
Topics: Animals; Antibodies, Monoclonal; Calcimycin; Cell Division; Cells, Cultured; DNA Damage; Down-Regulation; Interleukin-2; Interleukin-4; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Oleanolic Acid; Receptors, Immunologic; Sapogenins; Saponins; Signal Transduction; Spleen; T-Lymphocytes; Thymus Gland; Up-Regulation | 1995 |
Anti-growth effects with components of Sho-saiko-to (TJ-9) on cultured human hepatoma cells.
Topics: alpha-Fetoproteins; Antineoplastic Agents; Astringents; Carcinoma, Hepatocellular; Cell Cycle; Cell Death; Cell Division; DNA, Neoplasm; Drugs, Chinese Herbal; Flavanones; Flavonoids; Ginsenosides; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Liver Neoplasms; Oleanolic Acid; Panax; Plants, Medicinal; Sapogenins; Saponins; Tumor Cells, Cultured | 1993 |
Anti-inflammatory activity of saikosaponins from Heteromorpha trifoliata.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbohydrate Sequence; Female; Malawi; Mice; Molecular Sequence Data; Oleanolic Acid; Plants, Medicinal; Sapogenins; Saponins | 1995 |
Saikosaponin A-induced cell death of a human hepatoma cell line (HuH-7): the significance of the 'sub-G1 peak' in a DNA histogram.
Topics: Apoptosis; Carcinoma, Hepatocellular; Cell Death; Cell Nucleus; DNA, Neoplasm; Electrophoresis, Agar Gel; Flow Cytometry; Humans; Liver Neoplasms; Mitochondrial Swelling; Necrosis; Oleanolic Acid; Sapogenins; Saponins; Tumor Cells, Cultured | 1995 |
Characterization of the immunoregulatory action of saikosaponin-d.
Topics: Adjuvants, Immunologic; Animals; Blotting, Northern; Cell Division; Fluorescent Antibody Technique; Genes, fos; Glycyrrhetinic Acid; Glycyrrhizic Acid; Immunosuppressive Agents; Interleukin-2; Mice; Mice, Inbred C57BL; Oleanolic Acid; Phosphorylation; Receptors, Interleukin-2; Sapogenins; Saponins; Signal Transduction; Spleen; T-Lymphocytes; Tyrosine; Up-Regulation | 1994 |
Comparison between the effects of crude saikosaponin and 16, 16-dimethyl prostaglandin E2 on tannic acid-induced gastric mucosal damage in rats.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Diffusion; Electrolytes; Gastric Acid; Gastric Mucosa; Hydrolyzable Tannins; Male; Oleanolic Acid; Permeability; Rats; Rats, Sprague-Dawley; Sapogenins; Saponins; Stomach Ulcer; Vagotomy | 1993 |
[Isolation and identification of two new saponins from Bupleurum smithii Wolff].
Topics: Drugs, Chinese Herbal; Molecular Structure; Oleanolic Acid; Sapogenins; Saponins | 1993 |
Scrophulasaponins II-IV, new saikosaponin homologs from Scrophularia kakudensis FRANCH.
Topics: Carbohydrate Sequence; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Oleanolic Acid; Plants; Sapogenins; Saponins | 1993 |
Effects of saiboku-to (TJ-96) on the production of platelet-activating factor in human neutrophils.
Topics: Drugs, Chinese Herbal; Glycyrrhetinic Acid; Glycyrrhizic Acid; Humans; Immunosuppressive Agents; Medicine, Kampo; Neutrophils; Oleanolic Acid; Platelet Activating Factor; Sapogenins; Saponins | 1993 |
[Production of medicinal plants by soilless culture system. I. Studies of morphological characteristics and saikosaponins content in Bupleurum falcatum cultivated by Ebb & Flood system].
Topics: Botany; Oleanolic Acid; Plant Roots; Plants, Medicinal; Sapogenins; Saponins | 1995 |
Central administration of saikosaponin-d increases corticotropin-releasing factor mRNA levels in the rat hypothalamus.
Topics: Adrenocorticotropic Hormone; Animals; Brain; Corticotropin-Releasing Hormone; Hypothalamus; Injections, Intraventricular; Male; Oleanolic Acid; Pituitary Gland, Anterior; Pro-Opiomelanocortin; Rats; Rats, Wistar; RNA, Messenger; Sapogenins; Saponins | 1995 |
Saikosaponin b2-induced apoptosis of cultured B16 melanoma cell line through down-regulation of PKC activity.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Division; Cell Line; Cell Nucleus; DNA, Neoplasm; Dose-Response Relationship, Drug; Flow Cytometry; G1 Phase; Kinetics; Melanoma, Experimental; Mice; Oleanolic Acid; Protein Kinase C; Sapogenins; Saponins; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1996 |
Effects of nine active ingredients in Chinese herbal medicine sho-saiko-to on 2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide mutagenicity.
Topics: Animals; Antimutagenic Agents; Biotransformation; DNA Repair; Drugs, Chinese Herbal; Flavanones; Flavonoids; Furylfuramide; Ginsenosides; Male; Molecular Structure; Mutagenicity Tests; Mutagens; Oleanolic Acid; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Sapogenins; Saponins | 1995 |
Suppressive effects of sairei-to on monoclonal antibody 1-22-3-induced glomerulonephritis: analysis of effective components.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Blood Chemical Analysis; Drugs, Chinese Herbal; Female; Glomerulonephritis; Kidney; Oleanolic Acid; Proteinuria; Rats; Rats, Wistar; Sapogenins; Saponins | 1997 |
Saikosaponin homologues from Clinopodium spp. The structures of clinoposaponins XII-XX.
Topics: Carbohydrate Conformation; Magnetic Resonance Spectroscopy; Oleanolic Acid; Sapogenins; Saponins; Spectrometry, Mass, Fast Atom Bombardment | 1997 |
Saikosaponin homologues from Verbascum spp. The structures of mulleinsaponins I-VII.
Topics: Carbohydrate Sequence; Carbohydrates; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Oleanolic Acid; Plant Extracts; Sapogenins; Saponins; Terminology as Topic | 1997 |
Enzymes responsible for the metabolism of saikosaponins from Eubacterium sp. A-44, a human intestinal anaerobe.
Topics: alpha-L-Fucosidase; Anti-Inflammatory Agents, Non-Steroidal; Culture Media; Eubacterium; Feces; Glucosidases; Humans; Hydrogen-Ion Concentration; Intestines; Molecular Weight; Oleanolic Acid; Sapogenins; Saponins; Substrate Specificity | 1997 |
Properties of ginseng saponin inhibition of catecholamine secretion in bovine adrenal chromaffin cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Cardiac Glycosides; Catecholamines; Cattle; Central Nervous System Agents; Chromaffin Cells; Dose-Response Relationship, Drug; Ginsenosides; Glycyrrhizic Acid; Oleanolic Acid; Panax; Plants, Medicinal; Sapogenins; Saponins | 1998 |
Metabolism and pharmacokinetics of orally administered saikosaponin b1 in conventional, germ-free and Eubacterium sp. A-44-infected gnotobiote rats.
Topics: Animals; Anti-Allergic Agents; Antineoplastic Agents, Phytogenic; Eubacterium; Feces; Gastrointestinal Contents; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Oleanolic Acid; Permeability; Rats; Rats, Wistar; Sapogenins; Saponins | 1998 |
ELISA for the determination of saikosaponin a, an active component of Bupleuri Radix.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibody Specificity; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Oleanolic Acid; Ovalbumin; Plants, Medicinal; Rabbits; Sapogenins; Saponins | 1998 |
In vivo and in vitro antiinflammatory activity of saikosaponins.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Carbohydrate Sequence; Cell Survival; Cells, Cultured; Dinoprostone; Ear, External; Edema; Female; Humans; Leukotriene C4; Macrophages, Peritoneal; Male; Mice; Molecular Sequence Data; Oleanolic Acid; Plant Extracts; Plants, Medicinal; Sapogenins; Saponins; Tetradecanoylphorbol Acetate | 1998 |
[The structure activity relationship of saikosaponins and glycyrrhizin derivatives for Na+, K(+)-ATPase inhibiting action].
Topics: Cell-Free System; Glycyrrhizic Acid; Humans; Oleanolic Acid; Sapogenins; Saponins; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship | 1996 |
[Chemical constituents of the roots of Bupleurum longicaule Wall. ex DC. var. franchetii de Boiss and B. chaishoui Shan et Sheh].
Topics: Apiaceae; Drugs, Chinese Herbal; Oleanolic Acid; Plant Roots; Plants, Medicinal; Sapogenins; Saponins | 1996 |
Saikosaponin b2 induces differentiation without growth inhibition in cultured B16 melanoma cells.
Topics: Animals; Cell Cycle; Cell Differentiation; Cell Size; Fluorescent Antibody Technique; Melanins; Melanoma, Experimental; Mice; Monophenol Monooxygenase; Neoplasm Transplantation; Oleanolic Acid; Sapogenins; Saponins; Tumor Cells, Cultured | 1998 |
Production of antibody against saikosaponin a, an active component of bupleuri radix.
Topics: Animals; Antibodies; Carbohydrate Sequence; Cattle; Culture Media; Haptens; Immunosuppressive Agents; Molecular Sequence Data; Oleanolic Acid; Plants, Medicinal; Sapogenins; Saponins; Serum Albumin, Bovine | 1998 |
Saikosaponins from roots of Bupleurum scorzonerifolium.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Carbohydrate Conformation; Carbohydrate Sequence; China; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Oleanolic Acid; Plant Roots; Plants, Medicinal; Sapogenins; Saponins | 1999 |
Antagonism of saikosaponin-induced prostaglandin E2 release by baicalein in C6 rat glioma cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Drug Antagonism; Flavanones; Flavonoids; Glioma; Oleanolic Acid; Prostaglandin Antagonists; Rats; Sapogenins; Saponins; Tumor Cells, Cultured | 1999 |
High-performance liquid chromatographic analysis of saponin compounds in Bupleurum falcatum.
Topics: Chromatography, High Pressure Liquid; Magnoliopsida; Oleanolic Acid; Plant Roots; Quality Control; Reproducibility of Results; Sapogenins; Saponins | 2000 |
Effect of saikosaponin, a triterpene saponin, on apoptosis in lymphocytes: association with c-myc, p53, and bcl-2 mRNA.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase Inhibitors; Cell Survival; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Flow Cytometry; Gene Expression Regulation; Humans; In Situ Nick-End Labeling; Lymphocyte Count; Lymphocytes; Oleanolic Acid; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; RNA, Messenger; Sapogenins; Saponins; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2000 |
Saikosaponin v-1 from roots of Bupleurum chinense DC.
Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Bupleurum; China; Drugs, Chinese Herbal; Magnetic Resonance Spectroscopy; Molecular Structure; Oleanolic Acid; Plant Roots; Plants, Medicinal; Sapogenins; Saponins; Triterpenes | 2001 |
Involvement of p-15(INK4b) and p-16(INK4a) gene expression in saikosaponin a and TPA-induced growth inhibition of HepG2 cells.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Carrier Proteins; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent Kinase Inhibitor p16; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Liver Neoplasms; Oleanolic Acid; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sapogenins; Saponins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2001 |
[Advances in the study of anti-inflammatory and immunoregulatory effects of saikosaponins and their similar substances].
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Drugs, Chinese Herbal; Oleanolic Acid; Sapogenins; Saponins | 1998 |
Purification of saponin compounds in Bupleurum falcatum by solvent partitioning and preparative LC.
Topics: Bupleurum; Chromatography, Liquid; Molecular Structure; Oleanolic Acid; Sapogenins; Saponins; Solvents | 2001 |
[Saponins in Bupleurum smithii Wolff var. parvifolium Shan et Y. Li].
Topics: Bupleurum; Drugs, Chinese Herbal; Molecular Structure; Oleanolic Acid; Plants, Medicinal; Sapogenins; Saponins | 1998 |
[Saikosaponin-d up-regulates GR mRNA expression and induces apoptosis in HL-60 cells].
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; HL-60 Cells; Humans; Oleanolic Acid; Receptors, Glucocorticoid; RNA, Messenger; Sapogenins; Saponins; Up-Regulation | 1999 |
Efficient production of saikosaponins in Bupleurum falcatum root fragments combined with signal transducers.
Topics: Acetates; Calcium Chloride; Cyclopentanes; Oleanolic Acid; Oxylipins; Plants; Sapogenins; Saponins; Signal Transduction; Structure-Activity Relationship | 2001 |
[Effect of Saikosaponin-d on up-regulating GR mRNA expression and inhibiting cell growth in human leukemia cells].
Topics: Anti-Inflammatory Agents; Apoptosis; Cell Division; HL-60 Cells; Humans; Oleanolic Acid; Receptors, Glucocorticoid; RNA, Messenger; Sapogenins; Saponins; Up-Regulation | 2000 |
Antiviral activity of seven iridoids, three saikosaponins and one phenylpropanoid glycoside extracted from Bupleurum rigidum and Scrophularia scorodonia.
Topics: Animals; Antiviral Agents; Bupleurum; Carbohydrate Sequence; Cell Line; Chlorocebus aethiops; Cricetinae; Dose-Response Relationship, Drug; Glucosides; HeLa Cells; Herpesvirus 1, Human; Humans; Iridoids; Medicine, Traditional; Molecular Sequence Data; Oleanolic Acid; Phenols; Plant Extracts; Poliovirus; Pyrans; Sapogenins; Saponins; Scrophulariaceae; Vero Cells; Vesicular stomatitis Indiana virus | 2002 |
Induction of differentiation in rat C6 glioma cells with Saikosaponins.
Topics: 2',3'-Cyclic Nucleotide 3'-Phosphodiesterase; Animals; Antineoplastic Agents, Phytogenic; Bupleurum; Cell Differentiation; Cell Division; Dose-Response Relationship, Drug; Glioma; Glutamate-Ammonia Ligase; Medicine, Chinese Traditional; Oleanolic Acid; Phosphoric Diester Hydrolases; Plant Extracts; Plant Roots; Rats; Sapogenins; Saponins; Tumor Cells, Cultured | 2002 |
[A new saikosaponin from Bupleurum Chinese DC].
Topics: Bupleurum; Molecular Structure; Oleanolic Acid; Sapogenins; Saponins | 1998 |
[A new saikosaponin from Bupleurum chinense DC].
Topics: Bupleurum; Molecular Structure; Oleanolic Acid; Sapogenins; Saponins; Triterpenes | 1998 |
Characteristics and mechanism of enzyme secretion and increase in [Ca2+]i in Saikosaponin(I) stimulated rat pancreatic acinar cells.
Topics: Amylases; Animals; Calcium; Drugs, Chinese Herbal; In Vitro Techniques; Male; Oleanolic Acid; Pancreas; Rats; Rats, Wistar; Sapogenins; Saponins; Sincalide | 2002 |
Effect of saikosaponin-A, a triterpenoid glycoside, isolated from Bupleurum falcatum on experimental allergic asthma.
Topics: Animals; Anti-Allergic Agents; Asthma; Bronchoconstriction; Bupleurum; Dose-Response Relationship, Drug; Guinea Pigs; Histamine Antagonists; Histamine Release; In Vitro Techniques; Male; Molecular Structure; Muscle, Smooth; Oleanolic Acid; Ovalbumin; Passive Cutaneous Anaphylaxis; Rats; Rats, Wistar; Sapogenins; Saponins; Time Factors; Trachea | 2002 |
Production of Prosaikogenin F, Prosaikogenin G, Saikogenin F and Saikogenin G by the Recombinant Enzymatic Hydrolysis of Saikosaponin and their Anti-Cancer Effect.
Topics: Humans; Hydrolysis; Oleanolic Acid; Sapogenins; Saponins | 2022 |