saicar has been researched along with adenosine monophosphate in 11 studies
| Studies (saicar) | Trials (saicar) | Recent Studies (post-2010) (saicar) | Studies (adenosine monophosphate) | Trials (adenosine monophosphate) | Recent Studies (post-2010) (adenosine monophosphate) |
|---|---|---|---|---|---|
| 36 | 0 | 10 | 11,432 | 257 | 2,798 |
| Protein | Taxonomy | saicar (IC50) | adenosine monophosphate (IC50) |
|---|---|---|---|
| Fructose-1,6-bisphosphatase 1 | Sus scrofa (pig) | 1.3 | |
| Fructose-1,6-bisphosphatase 1 | Homo sapiens (human) | 2.6436 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 2.6 | |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | 0.1 | |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | 0.44 | |
| Histamine H3 receptor | Rattus norvegicus (Norway rat) | 0.8 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 5 (45.45) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jaeken, J; Van den Bergh, F; Van den Berghe, G; Vincent, MF | 4 |
| Van den Berghe, G; Vincent, MF | 1 |
| Borne, F; Daignan-Fornier, B; Desmoucelles, C; Pinson, B; Rébora, K | 1 |
| Marie, S; Race, V; Van den Berghe, G; Vincent, MF | 1 |
| Colman, RF; Palenchar, JB | 1 |
| Daignan-Fornier, B; Laloo, B; Rébora, K | 1 |
| Balaram, H; Bopanna, MP; Bulusu, V; Srinivasan, B | 1 |
| Calkins, LA; Capodagli, GC; Deaton, MK; Ghosh, K; Patterson, D; Pegan, SD; Ray, SP; Sawle, L | 1 |
11 other study(ies) available for saicar and adenosine monophosphate
| Article | Year |
|---|---|
Adenylosuccinase activity and succinylpurine production in fibroblasts of adenylosuccinase-deficient children.
Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Cells, Cultured; Child; Fibroblasts; Humans; Kinetics; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Ribonucleotides | 1991 |
Radiochemical assay of adenylosuccinase: demonstration of parallel loss of activity toward both adenylosuccinate and succinylaminoimidazole carboxamide ribotide in liver of patients with the enzyme defect.
Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Cold Temperature; Enzyme Stability; Fumarates; Humans; Liver; Male; Muscles; Rats; Rats, Inbred Strains; Ribonucleotides; Saccharomyces cerevisiae; Substrate Specificity | 1991 |
Influence of succinylpurines on the binding of adenosine to a particulate fraction of rat cerebral cortex.
Topics: Adenosine; Adenosine Monophosphate; Aminoimidazole Carboxamide; Animals; Cell Membrane; Cerebral Cortex; Imidazoles; Rats; Receptors, Purinergic; Ribonucleotides | 1989 |
Residual adenylosuccinase activities in fibroblasts of adenylosuccinase-deficient children: parallel deficiency with adenylosuccinate and succinyl-AICAR in profoundly retarded patients and non-parallel deficiency in a mildly retarded girl.
Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Binding, Competitive; Cells, Cultured; Child; Chromatography, Ion Exchange; Female; Fibroblasts; Humans; Hydrogen-Ion Concentration; Intellectual Disability; Kinetics; Nucleotides; Potassium Chloride; Ribonucleotides; Substrate Specificity | 1993 |
Functional studies in fibroblasts of adenylosuccinase-deficient children.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Cells, Cultured; Child; Fibroblasts; Formates; Humans; Hypoxanthine; Hypoxanthines; Intellectual Disability; Ribonucleotides | 1993 |
Yeast AMP pathway genes respond to adenine through regulated synthesis of a metabolic intermediate.
Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Alleles; Amidophosphoribosyltransferase; Aminoimidazole Carboxamide; Epistasis, Genetic; Feedback, Physiological; Fungal Proteins; Genes, Dominant; Homeodomain Proteins; Mutation; Protein Binding; Ribonucleotides; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Trans-Activators; Two-Hybrid System Techniques | 2001 |
Adenylosuccinate lyase deficiency: from the clinics to molecular biology.
Topics: Adenosine; Adenosine Monophosphate; Adenylosuccinate Lyase; Aminoimidazole Carboxamide; Enzyme Stability; Gene Expression; Heating; Humans; Recombinant Fusion Proteins; Ribonucleotides | 2000 |
Characterization of a mutant Bacillus subtilis adenylosuccinate lyase equivalent to a mutant enzyme found in human adenylosuccinate lyase deficiency: asparagine 276 plays an important structural role.
Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Amino Acid Sequence; Aminoimidazole Carboxamide; Arginine; Asparagine; Bacillus subtilis; Bacterial Proteins; Circular Dichroism; Enzyme Activation; Humans; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Point Mutation; Protein Structure, Secondary; Recombinant Proteins; Ribonucleotides; Substrate Specificity; Threonine | 2003 |
Revisiting purine-histidine cross-pathway regulation in Saccharomyces cerevisiae: a central role for a small molecule.
Topics: Adenosine Monophosphate; Aminoimidazole Carboxamide; Folic Acid; Gene Expression Regulation, Fungal; Histidine; Inosine Monophosphate; Purines; Ribonucleotides; Saccharomyces cerevisiae | 2005 |
Elucidation of the substrate specificity, kinetic and catalytic mechanism of adenylosuccinate lyase from Plasmodium falciparum.
Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Amino Acid Sequence; Aminoimidazole Carboxamide; Animals; Biocatalysis; Cyclic AMP; Escherichia coli; Humans; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Plasmodium falciparum; Protozoan Proteins; Recombinant Proteins; Ribonucleotides; Sequence Alignment; Substrate Specificity; Thermodynamics | 2009 |
Structural and biochemical characterization of human adenylosuccinate lyase (ADSL) and the R303C ADSL deficiency-associated mutation.
Topics: Adenosine Monophosphate; Adenylosuccinate Lyase; Amino Acid Sequence; Aminoimidazole Carboxamide; Autistic Disorder; Humans; Mutation, Missense; Purine-Pyrimidine Metabolism, Inborn Errors; Ribonucleotides; Sequence Alignment | 2012 |