safingol and serine

safingol has been researched along with serine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19904 (19.05)18.7374
1990's9 (42.86)18.2507
2000's5 (23.81)29.6817
2010's3 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lev, M; Milford, AF1
Birk, R; Brenner-Weiss, G; Sandhoff, K; Schmidt, RR; van Echten, G1
Merrill, AH; Messmer, TO; Stevens, VL; Wang, E1
Merrill, AH; Wang, E1
Medlock, KA; Merrill, AH1
Merrill, AH; Smith, ER1
Ridgway, ND1
Merriam, DL; Ridgway, ND1
Hamanoue, M; Inokuchi, J; Kohsaka, S; Usuki, S1
Badiani, K; Byers, DM; Cook, HW; Ridgway, ND1
Gillard, BK; Harrell, RG; Marcus, DM1
Bär, T; Heinemann, T; Raths, A; Sandhoff, K; Schmidt, RR; van Echten-Deckert, G; Zschoche, A1
Futerman, AH; Giannis, A; Sandhoff, K; Schwarz, A; van Echten-Deckert, G1
Bodennec, J; Brichon, G; Koul, O; Portoukalian, J; Zwingelstein, G1
Hara-Nishimura, I; Imai, H; Mitsuhashi, N; Tamura, K1
Guerrera, RL; Howell, AR; Izmirian, DP; Ndonye, R; Richardson, SK; So, RC1
Cowart, LA; Hannun, YA1
Ernst, D; Hornemann, T; Kivrak-Pfiffner, F; Penno, A; Rohrer, L; Rütti, MF; von Eckardstein, A1
Jang, Y; Jiang, Q; Rao, X1
Allikmets, R; Badur, MG; Bahlo, M; Baldini, M; Bernstein, PS; Bonelli, R; Cai, C; Dorrell, MI; Eade, K; Egan, C; Eichler, F; Fallon, R; Friedlander, M; Fruttiger, M; Gantner, ML; Giles, S; Gillies, M; Guymer, R; Handzlik, MK; Harkins-Perry, S; Hart, BJ; Heeren, TFC; Ideguchi, Y; Kitano, M; Metallo, CM; Nagasaki, T; Okada, M; Sauer, L; Scheppke, L; Trombley, J; Wallace, M; Woods, SM1
Abegg, D; Adibekian, A; Gentina, S; Gomez, L; Guex, N; Hannich, JT; Haribowo, AG; Martinou, JC; Ovize, M; Paillard, M; Pillot, B; Riezman, H; Thibault, H; Zumbuehl, A1

Other Studies

21 other study(ies) available for safingol and serine

ArticleYear
Dihydrosphingosine growth inhibition and repression of 3-ketodihydrosphingosine synthetase activity in Bacteroides melaninogenicus.
    Biochemical and biophysical research communications, 1978, Jul-14, Volume: 83, Issue:1

    Topics: Bacteroides; Dose-Response Relationship, Drug; Enzyme Repression; Kinetics; Oxo-Acid-Lyases; Palmitoyl Coenzyme A; Serine; Sphingosine

1978
Modulation of sphingolipid biosynthesis in primary cultured neurons by long chain bases.
    The Journal of biological chemistry, 1990, Jun-05, Volume: 265, Issue:16

    Topics: Animals; Antigens, CD; Carbohydrate Sequence; Cell Survival; Cells, Cultured; Cerebellum; Galactose; Gangliosides; Glycosphingolipids; Lactosylceramides; Mice; Molecular Sequence Data; Neurons; Serine; Sphingolipids; Sphingosine

1990
Sphingolipid biosynthesis by rat liver cells: effects of serine, fatty acids and lipoproteins.
    The Journal of nutrition, 1989, Volume: 119, Issue:4

    Topics: Acyltransferases; Animals; Cells, Cultured; Fatty Acids; Lipoproteins; Liver; Male; Palmitic Acid; Palmitic Acids; Rats; Serine; Serine C-Palmitoyltransferase; Sphingolipids; Sphingosine

1989
Biosynthesis of long-chain (sphingoid) bases from serine by LM cells. Evidence for introduction of the 4-trans-double bond after de novo biosynthesis of N-acylsphinganine(s).
    The Journal of biological chemistry, 1986, Mar-15, Volume: 261, Issue:8

    Topics: Acylation; Animals; Carbon Radioisotopes; Cells, Cultured; Mice; Serine; Sphingolipids; Sphingosine

1986
Inhibition of serine palmitoyltransferase in vitro and long-chain base biosynthesis in intact Chinese hamster ovary cells by beta-chloroalanine.
    Biochemistry, 1988, Sep-06, Volume: 27, Issue:18

    Topics: Acyltransferases; Alanine; Animals; beta-Alanine; Biological Transport, Active; Cells, Cultured; Cricetinae; Female; In Vitro Techniques; Lipids; Microsomes, Liver; Rats; Serine; Serine C-Palmitoyltransferase; Sphingolipids; Sphingosine

1988
Differential roles of de novo sphingolipid biosynthesis and turnover in the "burst" of free sphingosine and sphinganine, and their 1-phosphates and N-acyl-derivatives, that occurs upon changing the medium of cells in culture.
    The Journal of biological chemistry, 1995, Aug-11, Volume: 270, Issue:32

    Topics: Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Culture Media; Mice; Palmitic Acid; Palmitic Acids; Phosphatidylethanolamines; Serine; Sphingolipids; Sphingosine

1995
25-Hydroxycholesterol stimulates sphingomyelin synthesis in Chinese hamster ovary cells.
    Journal of lipid research, 1995, Volume: 36, Issue:6

    Topics: Animals; Ceramides; CHO Cells; Cholesterol Esters; Choline; Cricetinae; Culture Media; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Synthase; Palmitic Acid; Palmitic Acids; Receptors, LDL; RNA, Messenger; Serine; Sphingomyelins; Sphingosine; Transferases (Other Substituted Phosphate Groups); Tritium

1995
Metabolism of short-chain ceramide and dihydroceramide analogues in Chinese hamster ovary (CHO) cells.
    Biochimica et biophysica acta, 1995, Apr-28, Volume: 1256, Issue:1

    Topics: Animals; Cell Membrane; Ceramides; CHO Cells; Choline; Cricetinae; Glucosylceramides; Kinetics; Serine; Sphingomyelins; Sphingosine; Tritium

1995
Induction of ganglioside biosynthesis and neurite outgrowth of primary cultured neurons by L-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol.
    Journal of neurochemistry, 1996, Volume: 67, Issue:5

    Topics: Animals; Carbon Radioisotopes; Cells, Cultured; Ceramides; Embryo, Mammalian; Enzyme Inhibitors; Female; Galactose; Gangliosides; Glycosphingolipids; Humans; Kinetics; Morpholines; Neurites; Neurons; Pregnancy; Radioisotope Dilution Technique; Rats; Rats, Wistar; Serine; Sphingomyelins; Sphingosine; Stereoisomerism; Tritium

1996
Effect of fumonisin B1 on phosphatidylethanolamine biosynthesis in Chinese hamster ovary cells.
    Biochimica et biophysica acta, 1996, Dec-13, Volume: 1304, Issue:3

    Topics: Animals; Carboxy-Lyases; CHO Cells; Cricetinae; Ethanolamine; Ethanolamines; Fumonisins; Mycotoxins; Nitrogenous Group Transferases; Phosphatidylethanolamines; Phosphatidylserines; Serine; Sphingomyelins; Sphingosine; Transferases

1996
Pathways of glycosphingolipid biosynthesis in SW13 cells in the presence and absence of vimentin intermediate filaments.
    Glycobiology, 1996, Volume: 6, Issue:1

    Topics: Acylation; Adrenal Cortex Neoplasms; Animals; Carcinoma, Small Cell; Ceramides; Endosomes; G(M1) Ganglioside; Galactose; Glucosamine; Glycosphingolipids; Golgi Apparatus; Humans; Mice; Serine; Sphingosine; Tumor Cells, Cultured; Vimentin

1996
cis-4-Methylsphingosine decreases sphingolipid biosynthesis by specifically interfering with serine palmitoyltransferase activity in primary cultured neurons.
    The Journal of biological chemistry, 1997, Jun-20, Volume: 272, Issue:25

    Topics: Acyltransferases; Animals; Cells, Cultured; Mice; Neurons; Serine; Serine C-Palmitoyltransferase; Sphingolipids; Sphingosine

1997
1-Methylthiodihydroceramide, a novel analog of dihydroceramide, stimulates sphinganine degradation resulting in decreased de novo sphingolipid biosynthesis.
    The Journal of biological chemistry, 1998, Jan-09, Volume: 273, Issue:2

    Topics: Animals; Cells, Cultured; Ceramides; Hippocampus; Hydrolysis; Mice; Neurons; Serine; Sphingolipids; Sphingosine

1998
Differential labelling of sphingolipids by [3H]serine and ([3H]methyl)-methionine in fish leukocytes.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2000, Volume: 125, Issue:4

    Topics: Animals; Bass; Isotope Labeling; Leukocytes; Serine; Sphingolipids; Sphingomyelins; Sphingosine; Tritium; Vitamin U

2000
Characterization of an Arabidopsis cDNA encoding a subunit of serine palmitoyltransferase, the initial enzyme in sphingolipid biosynthesis.
    Plant & cell physiology, 2001, Volume: 42, Issue:11

    Topics: Acyltransferases; Amino Acid Sequence; Arabidopsis; DNA, Complementary; DNA, Plant; Endoplasmic Reticulum; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Mutagenesis; Nicotiana; Open Reading Frames; Palmitoyl Coenzyme A; Protein Conformation; Saccharomyces cerevisiae; Serine; Serine C-Palmitoyltransferase; Sphingolipids; Sphingosine

2001
Straightforward synthesis of sphinganines via a serine-derived Weinreb amide.
    The Journal of organic chemistry, 2004, Apr-30, Volume: 69, Issue:9

    Topics: Amides; Ketones; Organometallic Compounds; Serine; Sphingosine; Stereoisomerism

2004
Selective substrate supply in the regulation of yeast de novo sphingolipid synthesis.
    The Journal of biological chemistry, 2007, Apr-20, Volume: 282, Issue:16

    Topics: Adaptor Proteins, Signal Transducing; Carrier Proteins; Gene Deletion; Gene Expression Regulation; Gene Expression Regulation, Fungal; Hot Temperature; Hydrogen-Ion Concentration; Membrane Proteins; Models, Biological; Mutagenesis; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Sphingolipids; Sphingosine; Substrate Specificity; Time Factors

2007
The SPTLC3 subunit of serine palmitoyltransferase generates short chain sphingoid bases.
    The Journal of biological chemistry, 2009, Sep-25, Volume: 284, Issue:39

    Topics: Catalysis; Cell Line; Chromatography, High Pressure Liquid; Gene Expression; Humans; Kinetics; Mass Spectrometry; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Serine C-Palmitoyltransferase; Sphingolipids; Sphingosine

2009
Gamma-tocotrienol profoundly alters sphingolipids in cancer cells by inhibition of dihydroceramide desaturase and possibly activation of sphingolipid hydrolysis during prolonged treatment.
    The Journal of nutritional biochemistry, 2017, Volume: 46

    Topics: Antineoplastic Agents; Carbon Isotopes; Cell Death; Cell Line, Tumor; Ceramides; Chromans; Chromatography, Liquid; Fatty Acid Desaturases; HCT116 Cells; Humans; MCF-7 Cells; Nitrogen Isotopes; Oxidative Stress; Oxidoreductases; Serine; Sphingolipids; Sphingosine; Tandem Mass Spectrometry; Vitamin E

2017
Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy.
    The New England journal of medicine, 2019, 10-10, Volume: 381, Issue:15

    Topics: Adult; Aged; Animals; Disease Models, Animal; DNA Mutational Analysis; Exome; Female; Hereditary Sensory and Autonomic Neuropathies; Humans; Lipid Metabolism; Macula Lutea; Male; Mice; Middle Aged; Mutation; Pedigree; Retinal Telangiectasis; Risk Factors; Serine; Serine C-Palmitoyltransferase; Sphingolipids; Sphingosine; Young Adult

2019
1-Deoxydihydroceramide causes anoxic death by impairing chaperonin-mediated protein folding.
    Nature metabolism, 2019, Volume: 1, Issue:10

    Topics: Alanine; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Cell Division; Chaperonins; Feeding Behavior; Hypoxia; Ion Channels; Mice; Mice, Inbred C57BL; Mutation; Myocardial Reperfusion Injury; Protein Folding; Saccharomyces cerevisiae; Serine; Sphingosine

2019
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