safinamide has been researched along with tyramine in 2 studies
| Studies (safinamide) | Trials (safinamide) | Recent Studies (post-2010) (safinamide) | Studies (tyramine) | Trials (tyramine) | Recent Studies (post-2010) (tyramine) |
|---|---|---|---|---|---|
| 199 | 29 | 159 | 5,823 | 164 | 762 |
| Protein | Taxonomy | safinamide (IC50) | tyramine (IC50) |
|---|---|---|---|
| trace amine-associated receptor 1 | Homo sapiens (human) | 0.8818 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Di Stefano, AF; Rusca, A | 1 |
| Astruc, B; Johne, A; Kovar, A; Krösser, S; Kupas, K; Marquet, A; Patat, A | 1 |
2 trial(s) available for safinamide and tyramine
| Article | Year |
|---|---|
Pressor response to oral tyramine during co-administration with safinamide in healthy volunteers.
Topics: Administration, Oral; Adrenergic Uptake Inhibitors; Alanine; Benzylamines; Blood Pressure; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Humans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Tyramine | 2011 |
The effect of safinamide, a novel drug for Parkinson's disease, on pressor response to oral tyramine: a randomized, double-blind, clinical trial.
Topics: Administration, Oral; Adult; Aged; Alanine; Benzylamines; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Parkinson Disease; Treatment Outcome; Tyramine; Young Adult | 2012 |