safinamide has been researched along with galantamine in 3 studies
| Studies (safinamide) | Trials (safinamide) | Recent Studies (post-2010) (safinamide) | Studies (galantamine) | Trials (galantamine) | Recent Studies (post-2010) (galantamine) |
|---|---|---|---|---|---|
| 199 | 29 | 159 | 1,874 | 209 | 703 |
| Protein | Taxonomy | safinamide (IC50) | galantamine (IC50) |
|---|---|---|---|
| Chain A, ACETYLCHOLINESTERASE | Tetronarce californica (Pacific electric ray) | 0.652 | |
| Chain A, Acetylcholinesterase | Tetronarce californica (Pacific electric ray) | 0.36 | |
| Acetylcholinesterase | Electrophorus electricus (electric eel) | 2.0401 | |
| Acetylcholinesterase | Tetronarce californica (Pacific electric ray) | 0.488 | |
| Cholinesterase | Homo sapiens (human) | 5.4792 | |
| Vascular endothelial growth factor receptor 1 | Homo sapiens (human) | 0.59 | |
| Acetylcholinesterase | Mus musculus (house mouse) | 2.29 | |
| Acetylcholinesterase | Homo sapiens (human) | 1.8484 | |
| Acetylcholinesterase | Bos taurus (cattle) | 4.53 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 8.3973 | |
| Vascular endothelial growth factor receptor 3 | Homo sapiens (human) | 0.59 | |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | 0.59 | |
| Acetylcholinesterase | Rattus norvegicus (Norway rat) | 0.8006 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 3.2 | |
| Cholinesterase | Equus caballus (horse) | 7.2215 | |
| Carboxylic ester hydrolase | Equus caballus (horse) | 8.4178 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Antonov, L; Atanasov, AG; Balacheva, AA; Faraone, I; Gastreich, M; Georgieva, MG; Hristova, S; Milella, L; Russo, D; Stammler, HG; Tzvetkov, NT | 1 |
| Brandão, P; Burke, AJ; Fernández-Bolaños, JG; Leitzbach, L; López, Ó; Pineiro, M; Stark, H | 1 |
| Alcaro, S; Bagetta, D; Burke, AJ; Carreiro, EP; Fernández-Bolaños, JG; Hagenow, S; Leitzbach, L; López, Ó; Marques, C; Moutayakine, A; Stark, H | 1 |
3 other study(ies) available for safinamide and galantamine
| Article | Year |
|---|---|
Carboxamides vs. methanimines: Crystal structures, binding interactions, photophysical studies, and biological evaluation of (indazole-5-yl)methanimines as monoamine oxidase B and acetylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Amides; Cell Proliferation; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Imines; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship; Tumor Cells, Cultured | 2019 |
Ugi Reaction Synthesis of Oxindole-Lactam Hybrids as Selective Butyrylcholinesterase Inhibitors.
Topics: | 2021 |
Evaluation of chromane derivatives: Promising privileged scaffolds for lead discovery within Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Butyrylcholinesterase; Cholinesterase Inhibitors; Horses; Kinetics; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship | 2022 |