saclofen has been researched along with phentolamine in 2 studies
| Studies (saclofen) | Trials (saclofen) | Recent Studies (post-2010) (saclofen) | Studies (phentolamine) | Trials (phentolamine) | Recent Studies (post-2010) (phentolamine) |
|---|---|---|---|---|---|
| 107 | 0 | 20 | 9,141 | 270 | 265 |
| Protein | Taxonomy | saclofen (IC50) | phentolamine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.396 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.006 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 10 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0316 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.018 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.11 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0492 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0492 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0492 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0316 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.0173 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.359 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.396 | |
| Alpha-1A adrenergic receptor | Homo sapiens (human) | 0.0011 | |
| Alpha-1B adrenergic receptor | Homo sapiens (human) | 0.0108 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 3.807 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0316 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.5495 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boudah, A; Granato, A; Jasmin, L; Ohara, PT; Rabkin, SD | 1 |
| Barchini, J; Jabbur, SJ; Linderoth, B; Meyerson, BA; Saadé, NE; Shamaa, F; Song, Z; Tchachaghian, S | 1 |
2 other study(ies) available for saclofen and phentolamine
| Article | Year |
|---|---|
Analgesia and hyperalgesia from GABA-mediated modulation of the cerebral cortex.
Topics: Animals; Baclofen; Bupivacaine; Cerebral Cortex; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Male; Models, Neurological; Neurons; Pain Threshold; Phentolamine; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Vigabatrin | 2003 |
Spinal segmental and supraspinal mechanisms underlying the pain-relieving effects of spinal cord stimulation: an experimental study in a rat model of neuropathy.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Baclofen; Bicuculline; Disease Models, Animal; Dopamine Antagonists; Electrodes; Female; GABA Antagonists; Hyperalgesia; Ketanserin; Methysergide; Neuralgia; Pain Measurement; Pain Threshold; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Spinal Cord; Sulpiride; Time Factors; Transcutaneous Electric Nerve Stimulation | 2012 |