saclofen has been researched along with baclofen in 100 studies
| Studies (saclofen) | Trials (saclofen) | Recent Studies (post-2010) (saclofen) | Studies (baclofen) | Trials (baclofen) | Recent Studies (post-2010) (baclofen) |
|---|---|---|---|---|---|
| 107 | 0 | 20 | 6,017 | 372 | 1,535 |
| Protein | Taxonomy | saclofen (IC50) | baclofen (IC50) |
|---|---|---|---|
| Gamma-aminobutyric acid type B receptor subunit 2 | Homo sapiens (human) | 0.05 | |
| Gamma-aminobutyric acid type B receptor subunit 2 | Rattus norvegicus (Norway rat) | 0.2762 | |
| Gamma-aminobutyric acid type B receptor subunit 1 | Homo sapiens (human) | 0.05 | |
| Gamma-aminobutyric acid type B receptor subunit 1 | Rattus norvegicus (Norway rat) | 0.2762 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 30 (30.00) | 18.2507 |
| 2000's | 50 (50.00) | 29.6817 |
| 2010's | 18 (18.00) | 24.3611 |
| 2020's | 2 (2.00) | 2.80 |
| Authors | Studies |
|---|---|
| Slaughter, MM; Tian, N | 1 |
| Bijak, M; Jarolimek, W; Misgeld, U | 1 |
| Olausson, B; Shyu, BC; Xu, ZQ | 1 |
| Scharfman, HE | 1 |
| Hei, DL; Mitsushima, D; Terasawa, E | 1 |
| Denavit-Saubié, M; Foutz, AS; Pierrefiche, O | 1 |
| Andersson, KE; Igawa, Y; Mattiasson, A | 1 |
| Billard, JM; Deisz, RA; Zieglgänsberger, W | 1 |
| Hoebel, BG; Mark, GP; Rada, PV | 1 |
| Kang, Y | 1 |
| Aoki, M; Kohama, I; Nakazono, Y; Sato, Y | 1 |
| Chapman, C; Herbison, AE; Poulain, DA; Voisin, DL | 1 |
| Bousquet, P; Feldman, J; Monassier, L; Roegel, JC; Tibiriça, E | 1 |
| Berthelot, P; Debaert, M; Flouquet, N; Kerr, DI; Ong, J; Vaccher, C; Vaccher, MP | 1 |
| Kombian, SB; Pittman, QJ; Zidichouski, JA | 1 |
| Kunos, G; Lovas, G; Palkovits, M; Varga, K | 1 |
| Fischer, Y; Parnas, I | 1 |
| El Manira, A; Grillner, S; Tegnér, J | 1 |
| Celada, P; Paladini, CA; Tepper, JM | 2 |
| Chen, H; Gustafsson, B; Pananceau, M | 1 |
| Funahashi, M; Stewart, M | 1 |
| DiMicco, JA; Monroe, AJ | 1 |
| Moises, HC; Rusin, KI | 1 |
| Fukuoka, M; Kubo, H; Muraki, M; Nakajima, S; Ohkawa, K; Tohda, Y | 1 |
| Higashi, H; Maeda, H; Shoji, Y; Tanaka, E; Yamamoto, S | 1 |
| Ibrahim, N; Kabashima, N; Setiadji, VS; Shibuya, I; Ueta, Y; Yamashita, H | 1 |
| Burrello, N; Calogero, AE; D'Agata, R; Ferrara, E; Fishel, S; Hall, J | 1 |
| Ajima, A; Kim, DS; Matsuda, Y; Ohki, K; Tanaka, S | 1 |
| Ezure, K; Miyazaki, M; Tanaka, I | 1 |
| Bargas, J; Barral, J; Galarraga, E; Toro, S | 1 |
| Chen, P; Chen, S; Lin, X | 1 |
| Delaleu, JC; Duchamp, A; Duchamp-Viret, P | 1 |
| Killackey, HP; Lane, RD; Rhoades, RW; Stojic, AS | 1 |
| Dixon, AK; Freeman, TC; Lee, K; Preston, Z; Richardson, PJ; Widdowson, L | 1 |
| Ishida, Y; Ishizuka, Y; Jin, QH; Kannan, H; Mitsuyama, Y | 1 |
| Park, HJ; Park, HS | 1 |
| Barker, JL; Behar, TN; Greene, CL; Schaffner, AE; Scott, CA | 1 |
| Elshourbagy, NA; Gager, TL; Hirst, WD; Jenkins, O; Minton, J; Murkitt, KL; Pangalos, M; Price, GW; Punia, PK; Rice, SQ; Shabon, U; Stammers, M; Taylor, SJ; Testa, T; Wood, MD | 1 |
| Koyama, T; Nishi, N; Odagaki, Y | 1 |
| Kato, K; Mikoshiba, K; Shin, RM | 1 |
| Bodnar, RJ; Christian, G; Echo, JA; Lamonte, N; Ragnauth, A; Znamensky, V | 1 |
| Asahi, Y; Yonehara, N | 1 |
| Hattori, T; Hida, W; Kikuchi, Y; Kurosawa, H; Ogawa, H; Okabe, S; Shirato, K; Tabata, M; Tun, Y | 1 |
| Hayakawa, K; Kamata, K; Kimura, M | 1 |
| Duchamp, A; Duchamp-Viret, P; Hardy, AB; Palouzier-Paulignan, B | 1 |
| Ang-Lee, MK; Aung, HH; Dey, L; Mehendale, S; Wang, A; Xie, JT; Yuan, CS | 1 |
| Gómez-Villafuertes, R; Gualix, J; Miras-Portugal, MT; Pintor, J | 2 |
| Connell, BJ; Saleh, TM | 1 |
| Greenfield, SA; Mann, EO | 1 |
| Ackerman, TF; Bodnar, RJ; Lamonte, N | 1 |
| Boudah, A; Granato, A; Jasmin, L; Ohara, PT; Rabkin, SD | 1 |
| Kaba, H; Okutani, F; Otsuka, T; Yagi, F; Zhang, JJ | 1 |
| Fernández-Pascual, S; Martín Del Río, R; Mukala-Nsengu-Tshibangu, A; Tamarit-Rodríguez, J | 1 |
| Allen, CN; Gompf, HS | 1 |
| Baber, SR; Fields, AM; Hoover, JM; Ibrahim, IN; Kaye, AD | 1 |
| Burrello, N; Calogero, AE; D'Agata, R; D'Amico, L; Satta, A; Vicari, E | 1 |
| Ovsepian, SV; Vesselkin, NP | 1 |
| Fields, AM; Hoover, JM; Ibrahim, IN; Kaye, AD; Richards, TA | 2 |
| Chen, G; Ebner, TJ; Gao, W; Hendrix, CM; Popa, LS; Reinert, KC; Ross, ME | 1 |
| Khodayar, MJ; Naderi, N; Shafaghi, B; Zarindast, MR | 1 |
| Bonte, JP; Foulon, C; Goossens, JF; Lipka, E; Vaccher, C; Vaccher, MP | 1 |
| Chai, CY; Cheng, YW; Ho, CM; Ku, MC; Su, CK | 1 |
| Akada, Y; Kato, Y; Mochizuki, H; Mori, R; Yamasaki, F | 1 |
| Höglund, AU; Kommalage, M | 1 |
| Ivenshitz, M; Segal, M | 1 |
| Bernal, SY; Bodnar, RJ; Dostova, I; Israel, Y; Kandov, Y; Kasselman, L; Kest, A; Verasammy, J | 1 |
| Duarte, ID; Reis, GM | 1 |
| Boehm, S; Dorostkar, MM | 1 |
| Ghijsen, WE; Lopes da Silva, FH; Zuiderwijk, M | 1 |
| Archer, DP; Nguyen, KQ; Roth, SH; Samanani, N | 1 |
| Beitz, AJ; Han, HJ; Kim, HW; Kwon, YB; Lee, JH; Roh, DH; Seo, HS; Yoon, SY | 1 |
| Aceves, J; Erlij, D; Florán, B; Nava-Asbell, C; Paz-Bermudez, F | 1 |
| Chancellor, MB; de Groat, WC; Hiragata, S; Miyazato, M; Sasatomi, K; Sugaya, K; Yoshimura, N | 1 |
| Calver, AR; McClellan, KM; Tobet, SA | 1 |
| Bossert, JM; Hope, BT; Koya, E; Shaham, Y; Uejima, JL; Wihbey, KA | 1 |
| Heinmiller, A; Ting-A-Kee, R; van der Kooy, D; Vargas-Perez, H; Yeh, A | 1 |
| Balon, N; Deschaseaux, F; Maddens, S; Tiberghien, P; Versaux-Botteri, C; Zangiacomi, V | 1 |
| Choi, JI; Huang, LJ; Kim, WM; Kim, YO; Lee, HG; Yoon, MH | 1 |
| Risso, JJ; Rostain, JC; Vallee, N | 1 |
| Faraji, F; Ghasemi, A; Motamedi, F; Zahediasl, S | 1 |
| Borges, AC; Faria, MS; Ganzer, L; Januário, AC; Kochenborger, L; Lopes, AP; Marino-Neto, J; Paschoalini, MA | 1 |
| Barchini, J; Jabbur, SJ; Linderoth, B; Meyerson, BA; Saadé, NE; Shamaa, F; Song, Z; Tchachaghian, S | 1 |
| Hsieh, KC; Lai, YY; Nguyen, D; Siegel, JM | 1 |
| Edeline, JM; Gaucher, Q; Gourévitch, B; Huetz, C | 1 |
| Ikeda, M; Kanazawa, T; Matsumoto, S; Nasu, M; Takahashi, M; Takeda, M | 1 |
| Cai, ZL; Li, CH; Liu, QY; Liu, WX; Wang, CY; Xiao, P; Xu, ST | 1 |
| Glinka, Y; Hasilo, C; Paraskevas, S; Prud'homme, GJ; Udovyk, O; Wang, Q | 1 |
| Kanazawa, T; Nasu, M; Shimazu, Y; Takeda, M | 1 |
| Duffy, AM; Harte-Hargrove, LC; Milner, TA; Scharfman, HE; Varga-Wesson, A | 1 |
| Borisova, T; Dudarenko, M; Pozdnyakova, N | 1 |
| Abdel-Galil, AG; El-Gowilly, SM; El-Mas, MM; Sallam, MY | 1 |
| Jiang, H; Jin, Q; Li, G; Li, Y; Lv, J; Wan, P; Wang, J | 1 |
| Chang, CH | 1 |
| Boulanger, JJ; Messier, C | 1 |
| Chang, CH; Grace, AA | 1 |
| Alavi, MS; Ghorbani, A; Hosseini, A; Negah, SS; Sadeghnia, HR | 1 |
| Cibulkova, L; Kotmanova, Z; Martvon, L; Poliacek, I; Simera, M; Veternik, M | 1 |
100 other study(ies) available for saclofen and baclofen
| Article | Year |
|---|---|
Pharmacology of the GABAB receptor in amphibian retina.
Topics: Ambystoma; Animals; Baclofen; Butylamines; Evoked Potentials; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; In Vitro Techniques; Membrane Potentials; Necturus; Organophosphorus Compounds; Propylamines; Receptors, GABA-B; Retina; Retinal Ganglion Cells; Stereoisomerism; Structure-Activity Relationship | 1994 |
Differences in the Cs block of baclofen and 4-aminopyridine induced potassium currents of guinea pig CA3 neurons in vitro.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Baclofen; GABA-B Receptor Antagonists; Guinea Pigs; Hippocampus; Organophosphorus Compounds; Potassium Channels; Receptors, GABA-B | 1994 |
Dorsal column inhibition of nociceptive thalamic cells mediated by gamma-aminobutyric acid mechanisms in the cat.
Topics: Afferent Pathways; Animals; Baclofen; Cats; Dental Pulp; Electric Stimulation; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Homocysteine; Pain; Picrotoxin; Spinal Cord; Thalamus | 1994 |
Paradoxical enhancement by bicuculline of dentate granule cell IPSPs evoked by fimbria stimulation in rat hippocampal slices.
Topics: Animals; Baclofen; Bicuculline; Electric Stimulation; Evoked Potentials; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Neurons; Rats; Receptors, GABA-A; Synapses; Synaptic Transmission; Time Factors | 1994 |
gamma-Aminobutyric acid is an inhibitory neurotransmitter restricting the release of luteinizing hormone-releasing hormone before the onset of puberty.
Topics: Animals; Baclofen; Behavior, Animal; Bicuculline; Female; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Macaca mulatta; Ovariectomy; Secretory Rate; Sexual Maturation; Statistics as Topic | 1994 |
Effects of GABAB receptor agonists and antagonists on the bulbar respiratory network in cat.
Topics: Animals; Baclofen; Cats; Decerebrate State; Dizocilpine Maleate; Evoked Potentials; Extracellular Space; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Medulla Oblongata; Nerve Net; Organophosphorus Compounds; Plethysmography; Receptors, GABA-A; Respiration | 1993 |
Effects of GABA-receptor stimulation and blockade on micturition in normal rats and rats with bladder outflow obstruction.
Topics: Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Female; GABA-A Receptor Antagonists; Hypertrophy; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Urinary Bladder; Urinary Bladder Neck Obstruction; Urination; Urodynamics | 1993 |
Pre- and postsynaptic GABAB receptors of rat neocortical neurons differ in their pharmacological properties.
Topics: Animals; Baclofen; Cerebral Cortex; Electric Stimulation; Feedback; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Neurons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synapses | 1993 |
In vivo modulation of acetylcholine in the nucleus accumbens of freely moving rats: II. Inhibition by gamma-aminobutyric acid.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Choline; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Infusions, Parenteral; Kinetics; Male; Muscimol; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Time Factors | 1993 |
Differential paired pulse depression of non-NMDA and NMDA currents in pyramidal cells of the rat frontal cortex.
Topics: Animals; Baclofen; Electric Stimulation; Electrophysiology; Frontal Lobe; GABA Antagonists; Muscarine; N-Methylaspartate; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Time Factors | 1995 |
Effects of GABA receptor antagonists on the raphe magnus-induced inhibition of bulbar and spinal respiratory neural activities in the cat.
Topics: Animals; Baclofen; Bicuculline; Cats; Female; GABA Antagonists; Male; Medulla Oblongata; Neurons; Picrotoxin; Receptors, GABA; Respiration; Spinal Cord | 1995 |
Effects of central GABAB receptor modulation upon the milk ejection reflex in the rat.
Topics: Animals; Baclofen; Electric Stimulation; Electroencephalography; Female; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Injections; Injections, Intraventricular; Microdialysis; Milk Ejection; Oxytocin; Rats; Rats, Wistar; Receptors, GABA-A; Supraoptic Nucleus | 1996 |
Evidence for a spinal origin of the effect of baclofen on the myocardial oxygen demand indexes.
Topics: Animals; Baclofen; Electric Stimulation; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; Hemodynamics; Male; Myocardium; Oxygen; Paraventricular Hypothalamic Nucleus; Rabbits; Spinal Cord | 1995 |
GABAB receptor antagonism by resolved (R)-saclofen in the guinea-pig ileum.
Topics: Animals; Baclofen; Chromatography, High Pressure Liquid; GABA Antagonists; GABA-B Receptor Antagonists; Guinea Pigs; Ileum; In Vitro Techniques; Stereoisomerism | 1996 |
GABAB receptors presynaptically modulate excitatory synaptic transmission in the rat supraoptic nucleus in vitro.
Topics: Animals; Baclofen; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; In Vitro Techniques; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Glutamate; Supraoptic Nucleus; Synaptic Transmission | 1996 |
Ethanol inhibition of stress-related tachycardia involves medullary NMDA receptors.
Topics: Animals; Baclofen; Bicuculline; Ethanol; GABA Agonists; GABA Antagonists; Male; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Stress, Physiological; Tachycardia | 1996 |
Differential activation of two distinct mechanisms for presynaptic inhibition by a single inhibitory axon.
Topics: Action Potentials; Animals; Astacoidea; Axons; Baclofen; Electric Stimulation; GABA Antagonists; Neural Inhibition; Neuromuscular Junction; Neurotransmitter Agents; Picrotoxin; Presynaptic Terminals; Receptors, GABA-A; Receptors, GABA-B | 1996 |
Locomotor-related presynaptic modulation of primary afferents in the lamprey.
Topics: Afferent Pathways; Animals; Axons; Baclofen; Bicuculline; Functional Laterality; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; In Vitro Techniques; Lampreys; Locomotion; Membrane Potentials; Motor Activity; N-Methylaspartate; Neurons, Afferent; Receptors, GABA-A; Receptors, GABA-B; Skin; Spinal Cord; Synapses | 1997 |
GABAergic control of the firing pattern of substantia nigra dopaminergic neurons.
Topics: Animals; Baclofen; Bicuculline; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Kinetics; Muscimol; Neurons; Rats; Receptors, GABA-A; Receptors, GABA-B; Substantia Nigra | 1998 |
Short-term facilitation evoked during brief afferent tetani is not altered by long-term potentiation in the guinea-pig hippocampal CA1 region.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Animals; Baclofen; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Membrane Potentials; Neurons, Afferent; Patch-Clamp Techniques; Picrotoxin; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes | 1998 |
GABA receptor-mediated post-synaptic potentials in the retrohippocampal cortices: regional, laminar and cellular comparisons.
Topics: Animals; Baclofen; Electric Stimulation; Entorhinal Cortex; Evoked Potentials; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA | 1998 |
GABAB receptors in the dorsomedial hypothalamus and heart rate in anesthetized rats.
Topics: Anesthetics; Animals; Baclofen; Bicuculline; Blood Pressure; GABA Agonists; GABA Antagonists; Heart Rate; Hypothalamus, Middle; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 1998 |
Mu-opioid and GABA(B) receptors modulate different types of Ca2+ currents in rat nodose ganglion neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesics, Opioid; Animals; Baclofen; Cadmium; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, N-Type; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA Agonists; GABA Antagonists; Naloxone; Narcotic Antagonists; Nerve Tissue Proteins; Neurons; Nifedipine; Nodose Ganglion; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Patch-Clamp Techniques; Peptides; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Opioid, mu; Spider Venoms | 1998 |
Role of GABA receptors in the bronchial response: studies in sensitized guinea-pigs.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Bronchi; Electric Stimulation; GABA Agonists; gamma-Aminobutyric Acid; Guinea Pigs; Male; Muscimol; Muscle Contraction; Muscle, Smooth; Ovalbumin; Trachea | 1998 |
Mechanisms underlying the enhancement of excitatory synaptic transmission in basolateral amygdala neurons of the kindling rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Baclofen; Bicuculline; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin | 1998 |
GABAB receptor-mediated inhibition of spontaneous action potential discharge in rat supraoptic neurons in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclofen; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; GABA Agonists; GABA Antagonists; In Vitro Techniques; Male; Neural Inhibition; Picrotoxin; Rats; Rats, Wistar; Receptors, GABA-B; Supraoptic Nucleus | 1998 |
Striatal, pallidal, and pars reticulata evoked inhibition of nigrostriatal dopaminergic neurons is mediated by GABA(A) receptors in vivo.
Topics: Afferent Pathways; Animals; Baclofen; Bicuculline; Corpus Striatum; Dopamine; Electric Stimulation; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Globus Pallidus; Male; Nerve Degeneration; Neurons; Phosphinic Acids; Picrotoxin; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Substantia Nigra | 1999 |
Gamma-aminobutyric acid (GABA) A and B receptors mediate the stimulatory effects of GABA on the human sperm acrosome reaction: interaction with progesterone.
Topics: Acrosome; Analysis of Variance; Baclofen; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Male; Muscimol; Picrotoxin; Progesterone; Prospective Studies; Receptors, GABA-A; Receptors, GABA-B | 1999 |
GABA-mediated representation of temporal information in rat barrel cortex.
Topics: Animals; Baclofen; Bicuculline; Brain Chemistry; Evoked Potentials, Somatosensory; GABA Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Rats; Rats, Long-Evans; Somatosensory Cortex; Time Perception; Vibrissae | 1999 |
Excitatory and inhibitory synaptic inputs shape the discharge pattern of pump neurons of the nucleus tractus solitarii in the rat.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclofen; Bicuculline; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Neural Inhibition; Neurons; Rats; Rats, Wistar; Reaction Time; Receptors, N-Methyl-D-Aspartate; Solitary Nucleus; Strychnine; Synapses | 1999 |
GABAergic presynaptic inhibition of rat neostriatal afferents is mediated by Q-type Ca(2+) channels.
Topics: Animals; Baclofen; Calcium Channel Blockers; Calcium Channels, Q-Type; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Neostriatum; Neural Inhibition; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-B | 2000 |
Activation of metabotropic GABAB receptors inhibited glutamate responses in spiral ganglion neurons of mice.
Topics: Age Factors; Animals; Animals, Newborn; Auditory Pathways; Baclofen; Bicuculline; Cells, Cultured; Cochlea; Dose-Response Relationship, Drug; Embryo, Mammalian; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hair Cells, Auditory; Mice; Neurons; Polymerase Chain Reaction; Receptors, GABA-B; Spiral Ganglion | 2000 |
GABA(B)-mediated action in the frog olfactory bulb makes odor responses more salient.
Topics: Animals; Baclofen; GABA Antagonists; Membrane Potentials; Odorants; Olfactory Bulb; Olfactory Pathways; Olfactory Receptor Neurons; Rana ridibunda; Reaction Time; Receptors, GABA-B | 2000 |
Suppression of hindlimb inputs to S-I forelimb-stump representation of rats with neonatal forelimb removal: GABA receptor blockade and single-cell responses.
Topics: Amputation Stumps; Animals; Animals, Newborn; Baclofen; Bicuculline; Cytoplasmic Granules; Forelimb; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Hindlimb; Motor Cortex; Neurons; Rats | 2000 |
Adenosine receptor expression and function in rat striatal cholinergic interneurons.
Topics: Acetylcholine; Adenosine; Adenosine Deaminase; Animals; Baclofen; Bicuculline; Caffeine; Cholinergic Fibers; Corpus Striatum; Dose-Response Relationship, Drug; GABA Antagonists; Gene Expression; Male; Membrane Potentials; Naloxone; Narcotic Antagonists; Neurons; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA, Messenger; Tritium; Xanthines | 2000 |
GABA(A) and GABA(B) receptors modulating basal and footshock-induced nitric oxide releases in rat prefrontal cortex.
Topics: Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Electroshock; Extracellular Space; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Microdialysis; Muscimol; Nitrates; Nitric Oxide; Nitrites; Perfusion; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B | 2000 |
Effects of GABA on pancreatic exocrine secretion of rats.
Topics: Amylases; Animals; Baclofen; Bicuculline; Cholecystokinin; Dose-Response Relationship, Drug; Electric Stimulation; GABA Antagonists; gamma-Aminobutyric Acid; Gastrin-Releasing Peptide; Hormones; In Vitro Techniques; Pancreas; Rats; Receptors, GABA-A; Secretin; Somatostatin; Tetrodotoxin | 2000 |
GABA receptor antagonists modulate postmitotic cell migration in slice cultures of embryonic rat cortex.
Topics: Animals; Baclofen; Bicuculline; Bromodeoxyuridine; Cell Movement; Cellular Senescence; Cerebral Cortex; Chemotaxis; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Intermediate Filament Proteins; Mitosis; Nerve Tissue Proteins; Nestin; Neuroglia; Neurons; Organ Culture Techniques; Picrotoxin; Pregnancy; Rats; Receptors, GABA-A | 2000 |
The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen.
Topics: Animals; Baclofen; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Receptors, GABA; Receptors, GABA-B | 2000 |
Functional coupling of GABA(B) receptors with G proteins that are sensitive to N-ethylmaleimide treatment, suramin, and benzalkonium chloride in rat cerebral cortical membranes.
Topics: Adenylate Cyclase Toxin; Animals; Baclofen; Benzalkonium Compounds; Cell Membrane; Cerebral Cortex; Dose-Response Relationship, Drug; Ethylmaleimide; GABA Antagonists; GTP Phosphohydrolases; GTP-Binding Proteins; Male; Neurons; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Subcellular Fractions; Suramin; Virulence Factors, Bordetella | 2000 |
Polysynaptic excitatory pathways induce heterosynaptic depression in the rat auditory cortex.
Topics: 2-Amino-5-phosphonovalerate; Animals; Auditory Cortex; Baclofen; Bicuculline; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Male; Neural Inhibition; Neural Pathways; Neuronal Plasticity; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 2001 |
gamma-Aminobutyric acid receptor subtype antagonists differentially alter opioid-induced feeding in the shell region of the nucleus accumbens in rats.
Topics: Animals; Baclofen; Bicuculline; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Naltrexone; Narcotic Antagonists; Narcotics; Neurons; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Receptors, Opioid | 2001 |
Involvement of GABAergic systems in manifestation of pharmacological activity of desipramine.
Topics: Animals; Antidepressive Agents, Tricyclic; Baclofen; Desipramine; Freund's Adjuvant; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Muscimol; Picrotoxin; Rats; Rats, Sprague-Dawley; Reaction Time | 2001 |
Role of GABA within the nucleus tractus solitarii in the hypoxic ventilatory decline of awake rats.
Topics: Animals; Baclofen; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypoxia; Male; Microdialysis; Microinjections; Muscimol; Neurons; Organophosphorus Compounds; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Solitary Nucleus | 2001 |
Mechanism underlying gamma-aminobutyric acid-induced antihypertensive effect in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Baclofen; Blood Pressure; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscimol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Species Specificity; Systole; Time Factors; Vasoconstriction; Vasoconstrictor Agents | 2002 |
GABA(B) receptor-mediated inhibition of mitral/tufted cell activity in the rat olfactory bulb: a whole-cell patch-clamp study in vitro.
Topics: Animals; Baclofen; Electrophysiology; Female; GABA Agonists; GABA Antagonists; Male; Neural Inhibition; Olfactory Bulb; Olfactory Nerve; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA-B | 2002 |
Kavalactones and dihydrokavain modulate GABAergic activity in a rat gastric-brainstem preparation.
Topics: Animals; Baclofen; Drug Interactions; GABA Agents; GABA Agonists; GABA Antagonists; Kava; Lactones; Muscimol; Naloxone; Narcotic Antagonists; Plant Extracts; Pyrones; Rats; Rats, Sprague-Dawley; Solitary Nucleus; Stomach | 2002 |
GABAB receptor-mediated presynaptic potentiation of ATP ionotropic receptors in rat midbrain synaptosomes.
Topics: Adenosine Triphosphate; Animals; Baclofen; Calcium; Colforsin; Competitive Bidding; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Fura-2; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Immunohistochemistry; In Vitro Techniques; Mesencephalon; Muscimol; Nerve Tissue Proteins; Picrotoxin; Rats; Receptors, GABA-B; Receptors, Purinergic P2; Receptors, Purinergic P2X; Synaptosomes; Time Factors | 2003 |
Estrogen-induced autonomic effects are mediated by NMDA and GABAA receptors in the parabrachial nucleus.
Topics: Animals; Autonomic Nervous System; Baclofen; Baroreflex; Bicuculline; Blood Pressure; Cardiotonic Agents; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Estrogen Antagonists; Estrogens; Excitatory Amino Acid Antagonists; Fulvestrant; GABA Antagonists; Heart Rate; Male; Membrane Potentials; Phenylephrine; Piperazines; Pons; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Time Factors | 2003 |
Novel modulatory mechanisms revealed by the sustained application of nicotine in the guinea-pig hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; alpha7 Nicotinic Acetylcholine Receptor; Animals; Baclofen; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neuronal Plasticity; Nicotine; Nicotinic Agonists; Picrotoxin; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic | 2003 |
Lack of intersite GABA receptor subtype antagonist effects upon mu opioid receptor agonist-induced feeding elicited from either the ventral tegmental area or nucleus accumbens shell in rats.
Topics: Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Tegmentum Mesencephali | 2003 |
Analgesia and hyperalgesia from GABA-mediated modulation of the cerebral cortex.
Topics: Animals; Baclofen; Bupivacaine; Cerebral Cortex; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Male; Models, Neurological; Neurons; Pain Threshold; Phentolamine; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Vigabatrin | 2003 |
Modulation of olfactory learning in young rats through intrabulbar GABA(B) receptors.
Topics: Acyclic Monoterpenes; Animals; Animals, Newborn; Antioxidants; Avoidance Learning; Baclofen; Behavior, Animal; Benzaldehydes; Conditioning, Classical; GABA Agonists; GABA Antagonists; Monoterpenes; Odorants; Olfactory Bulb; Rats; Rats, Long-Evans; Receptors, GABA-A | 2003 |
GABA modulates presynaptic signalling mediated by dinucleotides on rat synaptic terminals.
Topics: Animals; Baclofen; Calcium; Calcium Signaling; Cyclic AMP-Dependent Protein Kinases; Dinucleoside Phosphates; GABA Agonists; gamma-Aminobutyric Acid; Mesencephalon; Nerve Endings; Presynaptic Terminals; Rats; Receptors, GABA-B | 2004 |
Conversion into GABA (gamma-aminobutyric acid) may reduce the capacity of L-glutamine as an insulin secretagogue.
Topics: 4-Aminobutyrate Transaminase; Adenosine Triphosphate; Allylglycine; Amination; Animals; Aspartic Acid; Baclofen; Bicuculline; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Insulin; Insulin Secretion; Islets of Langerhans; Ketoglutaric Acids; Leucine; Male; Oxidation-Reduction; Perfusion; Potassium Chloride; Rats; Rats, Wistar; Receptors, GABA | 2004 |
GABAergic synapses of the suprachiasmatic nucleus exhibit a diurnal rhythm of short-term synaptic plasticity.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Baclofen; Calcium; Circadian Rhythm; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethylmaleimide; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Male; Membrane Potentials; Models, Neurological; Neural Inhibition; Neuronal Plasticity; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Suprachiasmatic Nucleus; Synapses; Time Factors | 2004 |
Analysis of gamma-aminobutyric acid-mediated responses in the pulmonary vascular bed of the cat.
Topics: Animals; Baclofen; Blood Vessels; Cats; Dose-Response Relationship, Drug; Female; Glyburide; Lung; Male; Meclofenamic Acid; Organophosphorus Compounds; Receptors, GABA-A; Receptors, GABA-B | 2004 |
Human follicular fluid stimulates the sperm acrosome reaction by interacting with the gamma-aminobutyric acid receptors.
Topics: Acrosome Reaction; Analysis of Variance; Baclofen; Bicuculline; Female; Follicular Fluid; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Humans; Male; Osmolar Concentration; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Sperm Motility; Spermatozoa | 2004 |
Dual effect of GABA on descending monosynaptic excitatory postsynaptic potential in frog lumbar motoneurons.
Topics: Animals; Baclofen; Drug Interactions; Electric Stimulation; Evoked Potentials; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Lumbosacral Region; Motor Neurons; Rana ridibunda; Spinal Cord; Synapses; Synaptic Transmission | 2004 |
Analysis of responses to St. John's Wort in the feline pulmonary vascular bed.
Topics: Acetylcholine; Animals; Arachidonic Acid; Baclofen; Bicuculline; Bradykinin; Calcium Channel Agonists; Cats; Dose-Response Relationship, Drug; Female; GABA Antagonists; Hypericum; Male; Meclofenamic Acid; Muscimol; Nicardipine; Nitric Oxide Donors; Organophosphorus Compounds; Ornithine; Pinacidil; Plant Extracts; Prospective Studies; Pulmonary Artery; Pulmonary Circulation; Vasodilator Agents | 2004 |
Involvement of kv1 potassium channels in spreading acidification and depression in the cerebellar cortex.
Topics: Acetazolamide; Acids; Animals; Anticonvulsants; Baclofen; Bicuculline; Carbamazepine; Cerebral Cortex; Cortical Spreading Depression; Cyclin D2; Cyclins; Diagnostic Imaging; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Female; GABA Antagonists; Glutamic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neutral Red; Peptides; Potassium Channel Blockers; Potassium Channels; Reaction Time; Scorpion Venoms; Shaker Superfamily of Potassium Channels; Time Factors | 2005 |
Interaction between gamma-aminobutyric acid GABAB and cannabinoid CB1 receptors in spinal pain pathways in rat.
Topics: Analysis of Variance; Animals; Baclofen; Cyclohexanols; Dose-Response Relationship, Drug; Drug Interactions; Formaldehyde; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Injections, Spinal; Male; Pain; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, GABA-B; Rimonabant; Signal Transduction; Spinal Cord | 2005 |
Enantiomeric analysis of baclofen analogs by capillary zone electrophoresis, using highly sulfated cyclodextrins: Inclusion ionization constant pKa determination.
Topics: Baclofen; Buffers; Cyclodextrins; Electrophoresis, Capillary; GABA Agonists; GABA-B Receptor Agonists; Hydrogen-Ion Concentration; Stereoisomerism; Sulfonic Acids | 2005 |
GABAB-receptor-mediated suppression of sympathetic outflow from the spinal cord of neonatal rats.
Topics: Age Factors; Animals; Animals, Newborn; Baclofen; Cadmium; Calcium; Cesium; GABA Agonists; GABA Antagonists; Hypertension; Membrane Potentials; Neural Inhibition; Phosphinic Acids; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Spinal Cord; Splanchnic Nerves; Sympathetic Nervous System | 2005 |
Analgesic properties of the novel compound M43068 in rat models of acute and neuropathic pain.
Topics: Adrenergic alpha-Antagonists; Analgesics; Animals; Baclofen; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Formaldehyde; GABA Antagonists; GABA-B Receptor Antagonists; Hyperalgesia; Male; Neural Inhibition; Nociceptors; Pain; Pain Threshold; Prazosin; Propionates; Rats; Rats, Wistar; Sciatic Nerve; Sciatic Neuropathy; Sympathetic Nervous System; Time Factors; Touch | 2005 |
Involvement of spinal GABA receptors in the regulation of intraspinal acetylcholine release.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Microdialysis; Muscimol; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B | 2005 |
Simultaneous NMDA-dependent long-term potentiation of EPSCs and long-term depression of IPSCs in cultured rat hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Baclofen; Calcium; Cells, Cultured; Colforsin; Cyclic AMP; Evoked Potentials; Hippocampus; Long-Term Potentiation; Long-Term Synaptic Depression; Neuronal Plasticity; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Quinoxalines; Rats; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tetrodotoxin; Thionucleotides; Time Factors | 2006 |
GABA receptor subtype antagonists in the nucleus accumbens shell and ventral tegmental area differentially alter feeding responses induced by deprivation, glucoprivation and lipoprivation in rats.
Topics: Animals; Baclofen; Behavior, Animal; Bicuculline; Body Weight; Deoxyglucose; Dose-Response Relationship, Drug; Drug Interactions; Eating; Feeding Behavior; Food Deprivation; GABA Antagonists; Glucose; Lipids; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Thioglycolates; Time Factors; Ventral Tegmental Area | 2006 |
Analysis of responses to kava kava in the feline pulmonary vascular bed.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; Bradykinin; Calcium Channel Blockers; Calcium Channels; Cats; Cyclooxygenase Inhibitors; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; Kava; Lung; Meclofenamic Acid; Muscimol; Nicardipine; Nitric Oxide Synthase; Organophosphorus Compounds; Ornithine; Pinacidil; Plant Extracts; Receptors, GABA; Vasodilator Agents | 2006 |
Baclofen, an agonist at peripheral GABAB receptors, induces antinociception via activation of TEA-sensitive potassium channels.
Topics: Analgesics; Animals; Baclofen; Bicuculline; Cesium; Charybdotoxin; Dequalinium; GABA Agonists; GABA-B Receptor Agonists; Glyburide; Male; Potassium Channels; Rats; Rats, Wistar; Tetraethylammonium; Tolbutamide | 2006 |
Opposite effects of presynaptic 5-HT3 receptor activation on spontaneous and action potential-evoked GABA release at hippocampal synapses.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Animals, Newborn; Baclofen; Bicuculline; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Indoles; Inhibitory Postsynaptic Potentials; Neurons; Patch-Clamp Techniques; Potassium Chloride; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Tropisetron | 2007 |
Electrically evoked GABA release in rat hippocampus CA1 region and its changes during kindling epileptogenesis.
Topics: Animals; Anticonvulsants; Baclofen; Electric Stimulation; Epilepsy; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Male; Nipecotic Acids; Rats; Rats, Wistar | 2007 |
Pentobarbital enhances gamma-aminobutyric acid-mediated excitation without altering synaptic plasticity in rat hippocampus.
Topics: Adjuvants, Anesthesia; Animals; Baclofen; Bicarbonates; Bicuculline; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Neuronal Plasticity; Neurons; Pentobarbital; Rats; Receptors, GABA-A; Receptors, GABA-B; Synaptic Transmission; Time Factors | 2007 |
A spinal muscarinic M2 receptor-GABAergic disinhibition pathway that modulates peripheral inflammation in mice.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Anti-Inflammatory Agents; Autonomic Fibers, Preganglionic; Baclofen; Catecholamines; Cell Proliferation; Exudates and Transudates; GABA Antagonists; gamma-Aminobutyric Acid; Image Interpretation, Computer-Assisted; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred ICR; Neural Pathways; Neurons; Receptor, Muscarinic M2; Receptors, GABA-A; Receptors, GABA-B; Spinal Cord | 2007 |
GABA(B) receptor activation inhibits dopamine D1 receptor-mediated facilitation of [(3)H]GABA release in substantia nigra pars reticulata.
Topics: Animals; Baclofen; Benzazepines; Cyclic AMP-Dependent Protein Kinases; Data Interpretation, Statistical; Dopamine Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, GABA-B; Reserpine; Substantia Nigra | 2007 |
GABA receptor activation in the lumbosacral spinal cord decreases detrusor overactivity in spinal cord injured rats.
Topics: Animals; Baclofen; Bicuculline; Disease Models, Animal; Female; GABA Agonists; GABA Antagonists; Glutamate Decarboxylase; Injections, Spinal; Lumbar Vertebrae; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA; Sacrum; Spinal Cord; Spinal Cord Injuries; Urinary Bladder, Overactive; Urodynamics | 2008 |
GABAB receptors role in cell migration and positioning within the ventromedial nucleus of the hypothalamus.
Topics: Animals; Animals, Newborn; Baclofen; Cell Movement; Dose-Response Relationship, Drug; Embryo, Mammalian; Estrogen Receptor alpha; GABA Antagonists; In Vitro Techniques; Luminescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Protein Subunits; Receptors, GABA-A; Receptors, GABA-B; Ventromedial Hypothalamic Nucleus | 2008 |
Role of ventral medial prefrontal cortex in incubation of cocaine craving.
Topics: Animals; Baclofen; Behavior, Addictive; Behavior, Animal; Bicuculline; Cocaine; Conditioning, Operant; Cues; Dopamine Uptake Inhibitors; Extinction, Psychological; Extracellular Signal-Regulated MAP Kinases; GABA Agonists; GABA Antagonists; Male; Muscimol; Prefrontal Cortex; Rats; Rats, Long-Evans; Self Administration; Sucrose; Sweetening Agents; Time Factors | 2009 |
Tegmental pedunculopontine glutamate and GABA-B synapses mediate morphine reward.
Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Baclofen; Behavior, Animal; Bicuculline; Conditioning, Operant; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Male; Morphine; N-Methylaspartate; Narcotics; Pedunculopontine Tegmental Nucleus; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Glutamate; Reward | 2009 |
Human cord blood-derived hematopoietic and neural-like stem/progenitor cells are attracted by the neurotransmitter GABA.
Topics: AC133 Antigen; Antigens, CD; Baclofen; Bicuculline; Cell Differentiation; Cell Line; Cells, Cultured; Chemotaxis; Colony-Forming Units Assay; Fetal Blood; Flow Cytometry; Fluorescent Antibody Technique; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Gene Expression; Glycoproteins; Hematopoietic Stem Cells; Humans; Neurons; Peptides; Receptors, GABA-A; Receptors, GABA-B; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells | 2009 |
Effect of sildenafil on neuropathic pain and hemodynamics in rats.
Topics: Animals; Baclofen; Bicuculline; Blood Pressure; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Heart Rate; Hemodynamics; Male; Neuralgia; Pain Threshold; Phosphodiesterase Inhibitors; Piperazines; Purines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Sildenafil Citrate; Sulfones | 2010 |
A pressurized nitrogen counterbalance to cortical glutamatergic pathway stimulation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Asparagine; Aspartic Acid; Baclofen; Corpus Striatum; Dopamine; Glutamic Acid; Glutamine; Homovanillic Acid; Hyperbaric Oxygenation; Inert Gas Narcosis; Male; Nitrogen; Pressure; Rats; Rats, Sprague-Dawley | 2010 |
Time-dependent effect of GABA on glucose-stimulated insulin secretion from isolated islets in rat.
Topics: Animals; Baclofen; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Rats; Rats, Wistar; Time Factors | 2011 |
Effects of GABA ligands injected into the nucleus accumbens shell on fear/anxiety-like and feeding behaviours in food-deprived rats.
Topics: Animals; Anxiety; Baclofen; Behavior, Animal; Bicuculline; Eating; Fear; Feeding Behavior; Food Deprivation; GABA Agents; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Microinjections; Muscimol; Nucleus Accumbens; Rats; Rats, Wistar; Stereotaxic Techniques | 2012 |
Spinal segmental and supraspinal mechanisms underlying the pain-relieving effects of spinal cord stimulation: an experimental study in a rat model of neuropathy.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Baclofen; Bicuculline; Disease Models, Animal; Dopamine Antagonists; Electrodes; Female; GABA Antagonists; Hyperalgesia; Ketanserin; Methysergide; Neuralgia; Pain Measurement; Pain Threshold; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Spinal Cord; Sulpiride; Time Factors; Transcutaneous Electric Nerve Stimulation | 2012 |
New pathways and data on rapid eye movement sleep behaviour disorder in a rat model.
Topics: Animals; Baclofen; Brain Stem; Disease Models, Animal; Electroencephalography; Evoked Potentials, Auditory; GABA Antagonists; GABA-B Receptor Agonists; Inferior Colliculi; Male; Neural Pathways; Polysomnography; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; REM Sleep Behavior Disorder; Sleep, REM | 2013 |
Cortical inhibition reduces information redundancy at presentation of communication sounds in the primary auditory cortex.
Topics: Algorithms; Animal Communication; Animals; Auditory Cortex; Auditory Perception; Baclofen; Brain Mapping; Cerebral Cortex; Discrimination, Psychological; Electrophysiological Phenomena; Extracellular Space; Female; GABA Antagonists; Guinea Pigs; Male; Microinjections; Neurons; Patch-Clamp Techniques; Phosphinic Acids; Propanolamines; Pyridazines; Receptors, GABA-A; Receptors, GABA-B; Vocalization, Animal | 2013 |
Suppression of ATP-induced excitability in rat small-diameter trigeminal ganglion neurons by activation of GABAB receptor.
Topics: Action Potentials; Adenosine Triphosphate; Analysis of Variance; Animals; Animals, Newborn; Baclofen; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; Neurons; Patch-Clamp Techniques; Rats; Receptors, GABA-B; Receptors, Purinergic P2X3; Trigeminal Ganglion | 2013 |
Effects of intrahippocampal GABAB receptor antagonist treatment on the behavioral long-term potentiation and Y-maze learning performance.
Topics: Animals; Baclofen; Cognition; GABA-B Receptor Antagonists; Hippocampus; Long-Term Potentiation; Male; Maze Learning; Rats, Sprague-Dawley | 2014 |
GABA protects pancreatic beta cells against apoptosis by increasing SIRT1 expression and activity.
Topics: Animals; Apoptosis; Baclofen; Cell Line, Tumor; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gene Expression Regulation; Humans; Insulin-Secreting Cells; Muscimol; NAD; Picrotoxin; Primary Cell Culture; Rats; Receptors, GABA-A; Receptors, GABA-B; Signal Transduction; Sirtuin 1; Transcription Factor RelA | 2014 |
Activation of GABA(B) receptors potentiates inward rectifying potassium currents in satellite glial cells from rat trigeminal ganglia: in vivo patch-clamp analysis.
Topics: Animals; Baclofen; Barium; Dose-Response Relationship, Immunologic; GABA Antagonists; GABA-B Receptor Agonists; Immunohistochemistry; Male; Membrane Potentials; Microscopy, Fluorescence; Neuroglia; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Rats, Wistar; Receptors, GABA-B; Trigeminal Ganglion | 2015 |
Opioid receptor-dependent sex differences in synaptic plasticity in the hippocampal mossy fiber pathway of the adult rat.
Topics: Animals; Baclofen; Bicuculline; Dendritic Spines; Estrous Cycle; Female; GABA-A Receptor Antagonists; Hippocampus; Long-Term Potentiation; Male; Mossy Fibers, Hippocampal; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid; Sex Characteristics; Somatostatin; Synapses | 2015 |
New effects of GABAB receptor allosteric modulator rac-BHFF on ambient GABA, uptake/release, Em and synaptic vesicle acidification in nerve terminals.
Topics: Allosteric Regulation; Animals; Baclofen; Benzofurans; Cerebral Cortex; Dose-Response Relationship, Drug; Extracellular Space; GABA Agents; gamma-Aminobutyric Acid; Hippocampus; Male; Membrane Potentials; Protons; Rats, Wistar; Receptors, GABA-B; Synaptic Vesicles; Synaptosomes; Tritium | 2015 |
Central GABAA receptors are involved in inflammatory and cardiovascular consequences of endotoxemia in conscious rats.
Topics: Animals; Arterial Pressure; Baclofen; Bicuculline; Endotoxemia; GABA Agents; Heart Rate; Interleukin-6; Lipopolysaccharides; Male; Nipecotic Acids; Nitric Oxide; Rats, Wistar; Receptors, GABA-A; Tiagabine; Tumor Necrosis Factor-alpha; Vigabatrin | 2016 |
GABAB receptors in the hippocampal dentate gyrus are involved in spatial learning and memory impairment in a rat model of vascular dementia.
Topics: Animals; Baclofen; Dementia, Vascular; Dentate Gyrus; Disease Models, Animal; GABA Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Male; Memory Disorders; Myocardial Ischemia; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, GABA-B; Spatial Learning | 2016 |
Lateral Orbitofrontal Cortical Modulation on the Medial Prefrontal Cortex-Amygdala Pathway: Differential Regulation of Intra-Amygdala GABAA and GABAB Receptors.
Topics: Action Potentials; Amygdala; Animals; Baclofen; Bicuculline; Electric Stimulation; GABA Antagonists; Iontophoresis; Male; Neural Inhibition; Neural Pathways; Neurons; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, GABA-A; Receptors, GABA-B; Sensory Gating; Time Factors | 2017 |
Oligodendrocyte progenitor cells are paired with GABA neurons in the mouse dorsal cortex: Unbiased stereological analysis.
Topics: Animals; Baclofen; Cell Count; GABA Agents; GABAergic Neurons; Learning; Memory; Mice, Inbred C57BL; Mice, Transgenic; Neocortex; Neuronal Plasticity; Oligodendrocyte Precursor Cells; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B | 2017 |
Inhibitory Modulation of Orbitofrontal Cortex on Medial Prefrontal Cortex-Amygdala Information Flow.
Topics: Amygdala; Anesthesia; Animals; Baclofen; Bicuculline; Electric Stimulation; Emotions; Excitatory Amino Acid Agonists; Frontal Lobe; GABA Antagonists; gamma-Aminobutyric Acid; Male; Microelectrodes; N-Methylaspartate; Neural Inhibition; Neural Pathways; Neurons; Rats, Sprague-Dawley; Receptors, GABA | 2018 |
Levetiracetam promoted rat embryonic neurogenesis via NMDA receptor-mediated mechanism in vitro.
Topics: Animals; Baclofen; Biomarkers; Cell Differentiation; Cell Proliferation; Cell Survival; Dizocilpine Maleate; Doublecortin Protein; Embryo, Mammalian; Female; Levetiracetam; Male; Nerve Tissue Proteins; Neural Stem Cells; Neurogenesis; Neurons; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Spheroids, Cellular | 2021 |
Differential inhibition of cough by GABA
Topics: Animals; Baclofen; Bicuculline; Cats; Cough; GABA-B Receptor Antagonists; Microinjections; Solitary Nucleus | 2023 |