Compounds > saccharopine
Page last updated: 2024-09-04

saccharopine and 2-aminoadipic acid

saccharopine has been researched along with 2-aminoadipic acid in 12 studies

Compound Research Comparison

Studies
(saccharopine)		Trials
(saccharopine)		Recent Studies (post-2010)
(saccharopine)		Studies
(2-aminoadipic acid)		Trials
(2-aminoadipic acid)		Recent Studies (post-2010) (2-aminoadipic acid)
440215464121

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's3 (25.00)18.2507
2000's2 (16.67)29.6817
2010's5 (41.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Divry, P; Mathieu, M; Vianey-Liaud, C1
Chang, YF1
Alvarez, E; Esmahan, C; Martin, JF; Montenegro, E1
Perry, D; Sim, KL1
Johansson, E; Lindqvist, Y; Schneider, G; Steffens, JJ1
Campoy, S; Casqueiro, J; Martín, JF; Naranjo, L; Valmaseda, EM1
Almasi, JN; Bushnell, EA; Gauld, JW1
Fujimura, S; Kadowaki, M; Kobayashi, H; Kubota, M; Shibata, M; Watanabe, G1
Biffoni, M; Cappellari, M; De Maria, R; Grande, S; Guidoni, L; Luciani, AM; Pallini, R; Palma, A; Ricci-Vitiani, L; Rosi, A; Runci, D; Viti, V1
Arruda, P; Eberlin, MN; Laranjeira, ÂB; MacKenzie, A; Marques, LA; Pena, IA; Yunes, JA1
Crowther, LM; Mathis, D; Plecko, B; Poms, M1
Matthews, DE1

Reviews

2 review(s) available for saccharopine and 2-aminoadipic acid

ArticleYear
[Inborn errors of lysine metabolism].
    Annales de biologie clinique, 1991, Volume: 49, Issue:1

    Topics: 2-Aminoadipic Acid; Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Female; Glutarates; Humans; Infant; Infant, Newborn; Lysine; Male; Pipecolic Acids

1991
Review of Lysine Metabolism with a Focus on Humans.
    The Journal of nutrition, 2020, 10-01, Volume: 150, Issue:Suppl 1

    Topics: 2-Aminoadipic Acid; Acetyl Coenzyme A; Ammonia; Animals; Bacteria; Body Weight; Deficiency Diseases; Diet; Gastrointestinal Microbiome; Humans; Lysine; Nitrogen; Nutritional Requirements; Nutritional Status; Proteins; Urea

2020

Other Studies

10 other study(ies) available for saccharopine and 2-aminoadipic acid

ArticleYear
Lysine metabolism in the human and the monkey: demonstration of pipecolic acid formation in the brain and other organs.
    Neurochemical research, 1982, Volume: 7, Issue:5

    Topics: 2-Aminoadipic Acid; Adult; Animals; Brain; Female; Humans; Kidney; Liver; Lysine; Macaca mulatta; Pipecolic Acids; Spinal Cord

1982
Catabolism of lysine in Penicillium chrysogenum leads to formation of 2-aminoadipic acid, a precursor of penicillin biosynthesis.
    Applied and environmental microbiology, 1994, Volume: 60, Issue:6

    Topics: 2-Aminoadipic Acid; Lysine; Penicillins; Penicillium chrysogenum; Pipecolic Acids

1994
Analysis of swainsonine and its early metabolic precursors in cultures of Metarhizium anisopliae.
    Glycoconjugate journal, 1997, Volume: 14, Issue:5

    Topics: 2-Aminoadipic Acid; Chromatography, High Pressure Liquid; Lysine; Mitosporic Fungi; Pipecolic Acids; Swainsonine

1997
Crystal structure of saccharopine reductase from Magnaporthe grisea, an enzyme of the alpha-aminoadipate pathway of lysine biosynthesis.
    Structure (London, England : 1993), 2000, Oct-15, Volume: 8, Issue:10

    Topics: 2-Aminoadipic Acid; Amino Acid Sequence; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Fungal Proteins; Hydrogen Bonding; Ligands; Lysine; Magnaporthe; Models, Molecular; Molecular Sequence Data; NADP; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Saccharopine Dehydrogenases

2000
Lysine is catabolized to 2-aminoadipic acid in Penicillium chrysogenum by an omega-aminotransferase and to saccharopine by a lysine 2-ketoglutarate reductase. Characterization of the omega-aminotransferase.
    Molecular genetics and genomics : MGG, 2005, Volume: 274, Issue:3

    Topics: 2-Aminoadipic Acid; Amino Acid Sequence; Base Sequence; Chromatography, High Pressure Liquid; Lysine; Molecular Sequence Data; Penicillins; Penicillium chrysogenum; Saccharopine Dehydrogenases; Sequence Analysis, DNA; Transaminases

2005
A QM/MM-based computational investigation on the catalytic mechanism of saccharopine reductase.
    Molecules (Basel, Switzerland), 2011, Oct-12, Volume: 16, Issue:10

    Topics: 2-Aminoadipic Acid; Catalysis; Glutamic Acid; Lysine; Magnaporthe; NADP; Saccharopine Dehydrogenases

2011
Regulation of free glutamate content in meat by dietary lysine in broilers.
    Animal science journal = Nihon chikusan Gakkaiho, 2015, Volume: 86, Issue:4

    Topics: 2-Aminoadipic Acid; Animal Feed; Animals; Chickens; Dietary Supplements; Female; Food Quality; Glutamic Acid; Liver; Lysine; Meat; Muscles; Pipecolic Acids; RNA, Messenger; Saccharopine Dehydrogenases

2015
(1) H NMR spectroscopy of glioblastoma stem-like cells identifies alpha-aminoadipate as a marker of tumor aggressiveness.
    NMR in biomedicine, 2015, Volume: 28, Issue:3

    Topics: 2-Aminoadipic Acid; Adult; Aged; Biomarkers, Tumor; Brain Neoplasms; Cell Survival; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Lysine; Male; Metabolic Networks and Pathways; Mitochondria; Multivariate Analysis; Neoplasm Invasiveness; Neoplastic Stem Cells; Proton Magnetic Resonance Spectroscopy; Signal Processing, Computer-Assisted

2015
Mouse lysine catabolism to aminoadipate occurs primarily through the saccharopine pathway; implications for pyridoxine dependent epilepsy (PDE).
    Biochimica et biophysica acta. Molecular basis of disease, 2017, Volume: 1863, Issue:1

    Topics: 2-Aminoadipic Acid; Animals; Epilepsy; Female; Lysine; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Picolinic Acids; Pyridoxal Phosphate

2017
New insights into human lysine degradation pathways with relevance to pyridoxine-dependent epilepsy due to antiquitin deficiency.
    Journal of inherited metabolic disease, 2019, Volume: 42, Issue:4

    Topics: 2-Aminoadipic Acid; Aldehyde Dehydrogenase; Epilepsy; Humans; Lysine; Metabolic Networks and Pathways; Pipecolic Acids; Vitamin B 6

2019