saccharin has been researched along with phenobarbital in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (75.00) | 18.7374 |
| 1990's | 5 (20.83) | 18.2507 |
| 2000's | 1 (4.17) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Marx, JL | 1 |
| Jolicoeur, FB; Rondeau, DB; Wayner, MJ | 1 |
| Debiec-Rychter, M; Wang, CY | 1 |
| Cooper, BR; Ervin, GN | 1 |
| Ito, N | 1 |
| Imaida, K; Wang, CY | 1 |
| Ito, N; Kawazoe, Y; Kohda, K; Mera, Y; Tatematsu, M | 1 |
| Cefalo, RC; Isenhower, WD; Korach, KS; McLachlan, JA; Newbold, RR | 1 |
| Byard, JL; Goldberg, L | 1 |
| Furukawa, F; Hayashi, Y; Kokubo, T; Kurokawa, Y; Takahashi, M | 1 |
| Kamiya, T; Ninomiya, Y; Sakamoto, M; Yanagi, S | 1 |
| Fukushima, S; Hirose, M; Ito, N; Ogiso, T; Shirai, T; Tsuda, H | 1 |
| Fukushima, S; Imaida, K; Ito, N; Kurata, Y; Tsuda, H | 1 |
| Fukushima, S; Ito, N; Nakanishi, K; Shirai, T | 1 |
| Fukushima, S; Hagiwara, A; Ito, N; Nakanishi, K; Tamano, S | 1 |
| Ito, N; Nakanishi, K; Tatematsu, M; Tsuda, H | 1 |
| Currens, M; Iype, PT; Ray-Chaudhuri, R | 1 |
| Barone, FC; Singer, G; Wayner, EA; Wayner, MJ | 1 |
| Boynton, AL; Whitfield, JF | 1 |
| Dusinská, M; Gábelová, A; Slamenová, D | 1 |
| Whysner, J; Williams, GM | 1 |
| Morimoto, S | 1 |
| Baldwin, LA; Calabrese, EJ | 1 |
2 review(s) available for saccharin and phenobarbital
| Article | Year |
|---|---|
Organ-specific modifying effects of phenobarbital, saccharin and antioxidants on 2-stage chemical carcinogenesis.
Topics: Animals; Antioxidants; Ascorbic Acid; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Carcinogens; Colonic Neoplasms; Ethoxyquin; Glutathione Transferase; Mammary Neoplasms, Experimental; Methylnitronitrosoguanidine; Neoplasms, Experimental; Phenobarbital; Propyl Gallate; Rats; Rats, Inbred F344; Saccharin; Stomach Neoplasms; Substrate Specificity; Urinary Bladder Neoplasms | 1986 |
Epigenetic carcinogens: evaluation and risk assessment.
Topics: Animals; Butylated Hydroxyanisole; Carcinogens; Cyclohexenes; DNA; Humans; Limonene; Neoplasms, Experimental; Phenobarbital; Risk Assessment; Saccharin; Terpenes | 1996 |
22 other study(ies) available for saccharin and phenobarbital
| Article | Year |
|---|---|
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Tumor promoters: carcinogenesis gets more complicated.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Dietary Fats; Epidermal Growth Factor; Humans; Neoplasms; Ornithine Decarboxylase; Phenobarbital; Plasminogen Activators; Receptors, Drug; Saccharin; Smoking; Tetradecanoylphorbol Acetate | 1978 |
Effects of phenobarbital on saccharin and citric acid intake in fluid deprived rats.
Topics: Animals; Citrates; Drinking Behavior; Male; Phenobarbital; Rats; Saccharin; Stimulation, Chemical; Time Factors; Water Deprivation | 1976 |
Induction of DNA synthesis by sodium phenobarbital, uracil, and sodium saccharin in urinary bladder of the F344 rat.
Topics: Animals; Bromodeoxyuridine; Carcinogens; Cell Division; DNA; DNA Replication; Male; Phenobarbital; Rats; Rats, Inbred F344; Reference Values; Saccharin; Uracil; Urinary Bladder | 1990 |
Use of conditioned taste aversion as a conflict model: effects of anxiolytic drugs.
Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Avoidance Learning; Chlordiazepoxide; Conditioning, Operant; Isoproterenol; Male; Phenobarbital; Rats; Saccharin; Saline Solution, Hypertonic; Taste | 1988 |
Effect of sodium phenobarbital and sodium saccharin in AIN-76A diet on carcinogenesis initiated with N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide and N,N-dibutylnitrosamine in male F344 rats.
Topics: Animals; Esophageal Neoplasms; FANFT; Hydrogen-Ion Concentration; Liver Neoplasms, Experimental; Male; Neoplasms, Experimental; Nitrosamines; Phenobarbital; Rats; Rats, Inbred F344; Saccharin; Stomach Neoplasms; Thiazoles; Thyroid Neoplasms; Urinary Bladder Neoplasms | 1986 |
Ornithine decarboxylase activity and DNA synthesis in rats after long term treatment with butylated hydroxyanisole, sodium saccharin or phenobarbital.
Topics: Animals; Butylated Hydroxyanisole; DNA; Enzyme Induction; Liver; Male; Ornithine Decarboxylase; Phenobarbital; Rats; Rats, Inbred F344; Saccharin; Stomach; Urinary Bladder | 1986 |
Absence of estrogenic activity in some drugs commonly used during pregnancy.
Topics: Acetaminophen; Animals; Diethylstilbestrol; Dose-Response Relationship, Drug; Estrogens; Female; In Vitro Techniques; Mice; Mice, Inbred Strains; Organ Size; Phenobarbital; Pregnancy; Pregnancy, Animal; Receptors, Estrogen; Saccharin; Uterus | 1986 |
The metabolism of saccharin in laboratory animals.
Topics: Animals; Bile; Carbon Isotopes; Chromatography, Thin Layer; Feces; Female; Haplorhini; Male; Phenobarbital; Rats; Saccharin; Time Factors | 1973 |
Effects of sodium chloride, saccharin, phenobarbital and aspirin on gastric carcinogenesis in rats after initiation with N-methyl-N'-nitro-N-nitrosoguanidine.
Topics: Adenocarcinoma; Animals; Aspirin; Carcinogens; Male; Methylnitronitrosoguanidine; Phenobarbital; Rats; Saccharin; Sodium Chloride; Stomach Neoplasms | 1984 |
Decrease in L-type pyruvate kinase activity in rat liver by some promoters of hepatocarcinogenesis.
Topics: Animals; Carbon Tetrachloride Poisoning; Carcinogens; Diethylnitrosamine; Isoenzymes; Isomerism; Liver; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Phenobarbital; Phenytoin; Pyruvate Kinase; Rats; Rats, Inbred Strains; Saccharin | 1984 |
Effect of phenobarbital, polychlorinated biphenyl and sodium saccharin on hepatic and renal carcinogenesis in unilaterally nephrectomized rats given N-ethyl-N-hydroxyethylnitrosamine orally.
Topics: Animals; Carcinogens; Diethylnitrosamine; Kidney Neoplasms; Liver Neoplasms; Male; Neoplasms, Experimental; Nephrectomy; Nitrosamines; Phenobarbital; Polychlorinated Biphenyls; Rats; Rats, Inbred F344; Saccharin | 1981 |
Organ-specific promoting effect of phenobarbital and saccharin in induction of thyroid, liver, and urinary bladder tumors in rats after initiation with N-nitrosomethylurea.
Topics: Adenocarcinoma, Papillary; Animals; Cocarcinogenesis; Liver Neoplasms; Male; Methylnitrosourea; Nitrosourea Compounds; Organ Specificity; Papilloma; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred F344; Saccharin; Thyroid Neoplasms; Urinary Bladder Neoplasms | 1983 |
Effects of promoters on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in the rat.
Topics: 2-Acetylaminofluorene; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Dose-Response Relationship, Drug; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Membrane Potentials; Neoplasms, Experimental; Nitrosamines; Phenobarbital; Precancerous Conditions; Rats; Saccharin; Urinary Bladder Neoplasms | 1983 |
Organ-specific promoting effects of phenobarbital sodium and sodium saccharin in the induction of liver and urinary bladder tumors in male F344 rats.
Topics: 2-Acetylaminofluorene; Animals; Butylhydroxybutylnitrosamine; Cocarcinogenesis; Hyperplasia; Liver Neoplasms, Experimental; Male; Neoplasms, Experimental; Organ Specificity; Phenobarbital; Rats; Rats, Inbred F344; Saccharin; Urinary Bladder; Urinary Bladder Neoplasms | 1982 |
Analysis of the effects of promoting agents on liver and urinary bladder carcinogenesis in rats.
Topics: Animals; Carcinogens; Cocarcinogenesis; Dose-Response Relationship, Drug; Hyperplasia; Liver Neoplasms; Male; Neoplasms, Experimental; Phenobarbital; Rats; Rats, Inbred F344; Saccharin; Urinary Bladder; Urinary Bladder Neoplasms | 1982 |
Enhancement of sister-chromatid exchanges by tumour promoters.
Topics: Animals; Cell Cycle; Cell Line; Crossing Over, Genetic; Deoxyglucose; Dose-Response Relationship, Drug; Neoplasms, Experimental; Phenobarbital; Phorbols; Saccharin; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate | 1982 |
The taste aversion induction properties of two long duration barbiturates.
Topics: Animals; Avoidance Learning; Barbital; Barbiturates; Drinking Behavior; Male; Phenobarbital; Rats; Saccharin; Taste | 1980 |
Stimulation of DNA synthesis in calcium-deprived T51B liver cells by the tumor promoters phenobarbital, saccharin, and 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Calcium; Cell Cycle; Cells, Cultured; Cocarcinogenesis; DNA; Liver; Phenobarbital; Phorbol Esters; Phorbols; Rats; Saccharin; Stimulation, Chemical; Tetradecanoylphorbol Acetate | 1980 |
Role of cytoplasmic membrane in the screening of potential tumour promoters.
Topics: Animals; Carcinogens; Cell Line; Cell Membrane; Cell Membrane Permeability; Cell Survival; Cricetinae; Drug Evaluation, Preclinical; Glucose-6-Phosphate; Glucosephosphates; In Vitro Techniques; Phenobarbital; Saccharin; Tetradecanoylphorbol Acetate; Theophylline | 1995 |
Alteration of intercellular communication in a human urothelial carcinoma cell-line by tumor-promoting agents.
Topics: Adult; Anticonvulsants; Antioxidants; Butylated Hydroxyanisole; Carcinogens; Carcinoma, Transitional Cell; Cell Communication; Clone Cells; Cyclamates; DDT; Dose-Response Relationship, Drug; Humans; Male; Phenobarbital; Saccharin; Tryptophan; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Urothelium | 1996 |
Can the concept of hormesis Be generalized to carcinogenesis?
Topics: Animals; Caffeic Acids; Carcinogenicity Tests; Carcinogens; Cell Division; Dioxins; DNA Ligases; Dose-Response Relationship, Drug; Environmental Pollutants; Female; Humans; Hyperplasia; Keratinocytes; Kidney; Liver; Lung Neoplasms; Male; Mercury; Methylnitronitrosoguanidine; Neoplasms, Radiation-Induced; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley; Risk Assessment; Saccharin; Stomach; Testicular Neoplasms; Urinary Bladder; Urinary Bladder Neoplasms | 1998 |