Page last updated: 2024-08-16

saccharin and naloxone

saccharin has been researched along with naloxone in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199014 (37.84)18.7374
1990's10 (27.03)18.2507
2000's6 (16.22)29.6817
2010's7 (18.92)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Campillo, NE; Guerra, A; Páez, JA1
Pilcher, CW; Stolerman, IP1
Touzani, K; Velley, L1
Pournaghash, S; Riley, AL; Stevenson, GW1
Geter, B; Kautz, MA; Riley, AL; Smurthwaite, ST1
Akarid, K; Touzani, K; Velley, L1
Burns, G; Lynch, WC1
Belknap, JK1
Gosnell, BA; Majchrzak, MJ1
Lynch, WC1
Leavitt, B; Mucha, RF; Walker, MJ1
Jacquet, YF1
Amit, Z; Ng Cheong Ton, JM1
Devos, M; Le Magnen, J; Marfaing-Jallat, P; Miceli, D1
Duncan, HJ; Riley, AL; Zellner, DA1
De Witte, P1
Libby, L; Lynch, WC1
Reid, LD; Siviy, SM1
Cooper, SJ1
Gibbs, GL; Mickley, GA; Stevens, KE; White, GA1
Cooper, SJ; Turkish, S1
Barber, DJ; Cooper, SJ1
Beczkowska, IW; Bodnar, RJ; Bostock, ME; Koch, JE; Leibowitz, SF1
Ramirez, I1
Clifton, PG; Yeomans, MR1
Abdollahi, M; Habibi, L; Nikfar, S1
Cichelli, MJ; Lewis, MJ1
Bespalov, A; Danysz, W; Kashkin, V; Malyshkin, A; Neznanova, O; Sukhotina, I; Zakharova, E1
Andrade, L; De Castro e Silva, E; Fregoneze, J; Luz, PA; Miranda, N; Pereira, V1
Cañadas, F; Davis, CM; Rice, KC; Riley, AL; Stevenson, GW; Ullrich, T1
Acquas, E; Fois, GR; Muggironi, G; Peana, AT; Vinci, S; Zinellu, M1
Cobuzzi, JL; Desko, AG; Riley, AL1
Grigson, PS; Nyland, JE1
Kozlov, AP; Kramskaya, TA; Nizhnikov, ME; Spear, NE; Varlinskaya, EI1
Carroll, ME; Harris, AC; Holtz, NA; Radke, AK; Zlebnik, NE1
Alexander, DN; Grigson, PS; Nyland, JE1

Reviews

1 review(s) available for saccharin and naloxone

ArticleYear
The role of endorphins in animal learning and behavior.
    Neuroscience and biobehavioral reviews, 1980,Spring, Volume: 4, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Avoidance Learning; Behavior, Animal; Conditioning, Classical; Cues; Electroshock; Emotions; Endorphins; Learning; Lithium; Naloxone; Pain; Rats; Receptors, Opioid; Saccharin; Sensory Thresholds; Stress, Physiological; Taste; Toxins, Biological

1980

Other Studies

36 other study(ies) available for saccharin and naloxone

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Conditioned flavor aversions for assessing precipitated morphine abstinence in rats.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 4, Issue:2

    Topics: Animals; Male; Morphine; Naloxone; Rats; Saccharin; Taste

1976
Ibotenic acid lesion of the hypothalamic paraventricular nucleus produces weight gain but modifies neither preference nor aversion for saccharin.
    Physiology & behavior, 1992, Volume: 52, Issue:4

    Topics: Animals; Avoidance Learning; Brain Mapping; Conditioning, Classical; Dose-Response Relationship, Drug; Drinking; Ibotenic Acid; Male; Morphine; Naloxone; Neurons; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Saccharin; Sensory Thresholds; Taste; Water Deprivation; Weight Gain

1992
Antagonism of drug discrimination learning within the conditioned taste aversion procedure.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:1

    Topics: Animals; Avoidance Learning; Conditioning, Operant; Discrimination Learning; Female; Morphine; Naloxone; Rats; Saccharin; Taste

1992
Naloxone as a stimulus in drug discrimination learning: generalization to other opiate antagonists.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 41, Issue:1

    Topics: Animals; Cues; Diprenorphine; Discrimination Learning; Female; Generalization, Psychological; Nalorphine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Saccharin

1992
Modulation of saccharin preference by morphine and naloxone: inversion of drug effects as a function of saccharin concentration.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:1

    Topics: Animals; Choice Behavior; Dose-Response Relationship, Drug; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Saccharin; Water Deprivation

1991
Opioid effects on intake of sweet solutions depend both on prior drug experience and on prior ingestive experience.
    Appetite, 1990, Volume: 15, Issue:1

    Topics: Albinism; Animals; Drug Administration Schedule; Drug Interactions; Eating; Male; Naloxone; Narcotics; Rats; Rats, Inbred Strains; Saccharin; Sucrose

1990
Physical dependence induced by the voluntary consumption of morphine in inbred mice.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:2

    Topics: Animals; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Morphine Dependence; Naloxone; Reinforcement, Psychology; Saccharin; Self Administration; Species Specificity

1990
Centrally administered opioid peptides stimulate saccharin intake in nondeprived rats.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:4

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Dose-Response Relationship, Drug; Drinking Behavior; Eating; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Food Preferences; Male; Naloxone; Oligopeptides; Pyrrolidines; Rats; Rats, Inbred Strains; Saccharin; Time Factors

1989
Opiate blockade inhibits saccharin intake and blocks normal preference acquisition.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:4

    Topics: Animals; Avoidance Learning; Drinking Behavior; Endorphins; Food Preferences; Male; Naloxone; Rats; Receptors, Opioid; Saccharin; Taste

1986
Saccharin exposure increases the potency and aversive property of naloxone in drug-naive rats.
    Life sciences, 1988, Volume: 43, Issue:16

    Topics: Animals; Avoidance Learning; Body Temperature; Drug Synergism; Male; Naloxone; Rats; Rats, Inbred Strains; Saccharin

1988
Conditioned aversion during morphine maintenance in mice and rats.
    Physiology & behavior, 1973, Volume: 11, Issue:4

    Topics: Animals; Avoidance Learning; Body Weight; Conditioning, Classical; Dose-Response Relationship, Drug; Drinking; Drug Tolerance; Humans; Male; Mice; Morphine; Morphine Dependence; Naloxone; Rats; Saccharin; Substance Withdrawal Syndrome; Water

1973
Attenuation of ethanol-induced conditioned taste aversion by naloxazone: behavioral evidence for an opiate receptor-mediated morphine-ethanol interaction.
    Neuroscience letters, 1984, Jul-27, Volume: 48, Issue:2

    Topics: Animals; Avoidance Learning; Conditioning, Classical; Ethanol; Morphine; Naloxone; Rats; Receptors, Opioid; Saccharin; Taste

1984
Pain modulating and reward systems: a single brain mechanism?
    Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:5

    Topics: Animals; Brain; Glucose; Naloxone; Pain; Quinine; Rats; Receptors, Opioid; Reward; Saccharin; Taste

1980
Naloxone reduces alcohol intake in a free-choice procedure even when both drinking bottles contain saccharin sodium or quinine substances.
    Neuropsychobiology, 1984, Volume: 12, Issue:2-3

    Topics: Alcohol Drinking; Animals; Drinking Behavior; Endorphins; Male; Naloxone; Quinine; Rats; Reward; Saccharin; Satiety Response; Taste

1984
Naloxone suppresses intake of highly preferred saccharin solutions in food deprived and sated rats.
    Life sciences, 1983, Nov-07, Volume: 33, Issue:19

    Topics: Animals; Dose-Response Relationship, Drug; Eating; Food Deprivation; Male; Morphine; Naloxone; Rats; Rats, Inbred Strains; Saccharin; Satiation; Solutions

1983
Endophinergic modulation of acceptability of putative reinforcers.
    Appetite, 1983, Volume: 4, Issue:4

    Topics: Animals; Endorphins; Male; Naloxone; Quinine; Rats; Rats, Inbred Strains; Saccharin; Taste; Water

1983
Effects of opiate agonists and antagonists on fluid intake and saccharin choice in the rat.
    Neuropharmacology, 1983, Volume: 22, Issue:3

    Topics: Animals; Choice Behavior; Drinking Behavior; Enkephalins; Male; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Saccharin

1983
Changes in morphine self-administration after exposure to ionizing radiation: evidence for the involvement of endorphins.
    Life sciences, 1983, Aug-22, Volume: 33, Issue:8

    Topics: Animals; Cobalt Radioisotopes; Drinking Behavior; Endorphins; Male; Mice; Mice, Inbred C57BL; Morphine; Naloxone; Saccharin; Solutions

1983
Effects of naloxone and its quaternary analogue on fluid consumption in water-deprived rats.
    Neuropharmacology, 1983, Volume: 22, Issue:6

    Topics: Animals; Drinking Behavior; Kinetics; Male; Naloxone; Rats; Saccharin; Sodium Chloride; Structure-Activity Relationship; Water; Water Deprivation

1983
Evidence for serotonergic involvement in saccharin preference in a two-choice test in rehydrating rats.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:3

    Topics: Animals; Choice Behavior; Conditioning, Operant; Dose-Response Relationship, Drug; Drinking; Fenfluramine; Fluid Therapy; Male; Naloxone; Rats; Saccharin; Serotonin; Serotonin Receptor Agonists; Stereoisomerism; Taste; Water Deprivation

1994
Central opioid receptor subtype antagonists differentially reduce intake of saccharin and maltose dextrin solutions in rats.
    Brain research, 1993, Aug-06, Volume: 618, Issue:2

    Topics: Animals; Drinking Behavior; Enkephalin, Leucine-2-Alanine; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Polysaccharides; Rats; Rats, Sprague-Dawley; Saccharin

1993
Intragastric carbohydrate exerts both intake-stimulating and intake-suppressing effects.
    Behavioral neuroscience, 1997, Volume: 111, Issue:3

    Topics: Animals; Appetite; Conditioning, Classical; Dietary Carbohydrates; Energy Intake; Female; Motivation; Naloxone; Narcotic Antagonists; Polysaccharides; Rats; Saccharin; Satiety Response; Taste

1997
Exposure to sweetened solutions enhances the anorectic effect of naloxone but not d-fenfluramine.
    Physiology & behavior, 1997, Volume: 62, Issue:2

    Topics: Analysis of Variance; Animals; Appetite Depressants; Eating; Fenfluramine; Male; Naloxone; Narcotic Antagonists; Quinine; Rats; Saccharin; Sucrose; Sweetening Agents; Taste; Weight Gain

1997
Saccharin effects on morphine-induced antinociception in the mouse formalin test.
    Pharmacological research, 2000, Volume: 42, Issue:3

    Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Formaldehyde; Male; Mice; Morphine; Naloxone; Saccharin; Sweetening Agents

2000
Naloxone nonselective suppression of drinking of ethanol, sucrose, saccharin, and water by rats.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 72, Issue:3

    Topics: Alcohol Drinking; Animals; Drinking; Ethanol; Male; Naloxone; Rats; Rats, Sprague-Dawley; Saccharin; Sucrose

2002
The NMDA receptor channel blocker memantine and opioid receptor antagonist naltrexone inhibit the saccharin deprivation effect in rats.
    Behavioural pharmacology, 2004, Volume: 15, Issue:4

    Topics: Acamprosate; Animals; Choice Behavior; Ethanol; Male; Memantine; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Saccharin; Substance Withdrawal Syndrome; Sweetening Agents; Taurine

2004
Inhibition of water intake by the central administration of IL-1beta in rats: role of the central opioid system.
    Neuropeptides, 2006, Volume: 40, Issue:2

    Topics: Animals; Body Temperature; Dehydration; Dose-Response Relationship, Drug; Drinking; Humans; Hypernatremia; Hypovolemia; Injections, Intraventricular; Interleukin-1; Male; Motor Activity; Naloxone; Narcotic Antagonists; Rats; Rats, Wistar; Saccharin; Water Deprivation

2006
Discriminative stimulus properties of naloxone in Long-Evans rats: assessment with the conditioned taste aversion baseline of drug discrimination learning.
    Psychopharmacology, 2009, Volume: 203, Issue:2

    Topics: Animals; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Naloxone; Narcotic Antagonists; Rats; Rats, Long-Evans; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Saccharin; Taste

2009
Effect of opioid receptor blockade on acetaldehyde self-administration and ERK phosphorylation in the rat nucleus accumbens.
    Alcohol (Fayetteville, N.Y.), 2011, Volume: 45, Issue:8

    Topics: Acetaldehyde; Animals; Enzyme Activation; Ethanol; Extracellular Signal-Regulated MAP Kinases; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Phosphorylation; Rats; Rats, Wistar; Receptors, Opioid, mu; Reinforcement, Psychology; Saccharin; Self Administration

2011
Naloxone-induced taste aversions in opiate-naïve Lewis and Fischer 344 rat strains.
    Drug and alcohol dependence, 2012, Apr-01, Volume: 122, Issue:1-2

    Topics: Animals; Avoidance Learning; Conditioning, Psychological; Dose-Response Relationship, Drug; Male; Naloxone; Narcotic Antagonists; Rats; Rats, Inbred F344; Rats, Inbred Lew; Saccharin; Species Specificity; Taste

2012
A drug-paired taste cue elicits withdrawal and predicts cocaine self-administration.
    Behavioural brain research, 2013, Mar-01, Volume: 240

    Topics: Animals; Cocaine; Cocaine-Related Disorders; Conditioning, Psychological; Cues; Disease Models, Animal; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Recurrence; Reward; Saccharin; Substance Withdrawal Syndrome; Sweetening Agents; Taste

2013
Central effects of ethanol interact with endogenous mu-opioid activity to control isolation-induced analgesia in maternally separated infant rats.
    Behavioural brain research, 2014, Mar-01, Volume: 260

    Topics: Animals; Central Nervous System Depressants; Drinking Behavior; Drinking Water; Ethanol; Female; Grooming; Male; Maternal Deprivation; Motor Activity; Naloxone; Narcotic Antagonists; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Saccharin; Social Isolation; Somatostatin; Stress, Psychological

2014
Intracranial self-stimulation reward thresholds during morphine withdrawal in rats bred for high (HiS) and low (LoS) saccharin intake.
    Brain research, 2015, Mar-30, Volume: 1602

    Topics: Animals; Animals, Outbred Strains; Electric Stimulation; Food Preferences; Genetic Predisposition to Disease; Implantable Neurostimulators; Male; Morphine; Naloxone; Narcotics; Random Allocation; Rats, Sprague-Dawley; Reward; Saccharin; Self Stimulation; Species Specificity; Substance Withdrawal Syndrome

2015
Drug-motivated behavior in rats with lesions of the thalamic orosensory area.
    Behavioral neuroscience, 2016, Volume: 130, Issue:1

    Topics: Analysis of Variance; Anesthetics, Local; Animals; Body Weight; Cocaine; Conditioning, Psychological; Drug-Seeking Behavior; Male; Motivation; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reward; Saccharin; Statistics as Topic; Sweetening Agents; Taste; Taste Perception; Thalamus

2016